Research Topics
| David B AllenSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Growth hormone therapy for Prader-Willi syndrome: a critical appraisalDavid B Allen
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792 4108, USA
J Pediatr Endocrinol Metab 17:1297-306. 2004..Consequently, critical evaluation should continue of the long-term benefits, risks, and costs of GH therapy for patients with PWS...- Fitness is a stronger predictor of fasting insulin levels than fatness in overweight male middle-school childrenDavid B Allen
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison 53792, USA
J Pediatr 150:383-7. 2007..We studied the relationship between % body fat (%BF), cardiovascular fitness (CVF), and insulin resistance (IR) in overweight middle-school children... - Growth hormone therapy for short stature: is the benefit worth the burden?David B Allen
Department of Pediatrics, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, Wisconsin 53792 4108, USA
Pediatrics 118:343-8. 2006 
Clinical review: Lessons learned from the hGH eraDavid B Allen
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
J Clin Endocrinol Metab 96:3042-7. 2011....- Growth-attenuation therapy: principles for practiceDavid B Allen
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, WI 53792 4108, USA
Pediatrics 123:1556-61. 2009..Because of the publicity and debate surrounding the first reported case, ethics consultation is recommended... - Inhaled steroids for children: effects on growth, bone, and adrenal functionDavid B Allen
University of Wisconsin Children s Hospital, Madison, WI 53792, USA
Endocrinol Metab Clin North Am 34:555-64, viii. 2005..Recent studies confirm that benefits of inhaled corticosteroids outweigh potential adverse effects and the risks associated with poorly controlled asthma... - Effects of inhaled steroids on growth, bone metabolism, and adrenal functionDavid B Allen
University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
Adv Pediatr 53:101-10. 2006..ICS are highly effective and, because their benefits clearly exceed potential risks, can be used safely in children who have persistent asthma... - Effects of inhaled steroids on growth, bone metabolism and adrenal functionDavid B Allen
Professor of Pediatrics, Director of Pediatric Endocrinology and Pediatric Residency Training, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
Expert Rev Respir Med 1:65-74. 2007..Overall, however, recent studies confirm that benefits of inhaled corticosteroids, properly prescribed and used, clearly outweigh not only their potential adverse effects, but also the risks associated with poorly controlled asthma... - School-based exercise improves fitness, body composition, insulin sensitivity, and markers of inflammation in non-obese childrenAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792, USA
J Pediatr Endocrinol Metab 22:409-15. 2009..Whether such a program improves CVF, IR, and other health indicators in non-obese children is unresolved... - Measuring aerobic cycling power as an assessment of childhood fitnessAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin, USA
J Strength Cond Res 22:192-5. 2008..Thus, accurate assessment of childhood aerobic fitness may be achievable by measurement of power, possibly within the school environment, at substantially less cost and effort than laboratory-based measurements... 
Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasoneTheresa W Guilbert
Department of Pediatrics, University of Wisconsin Madison, Wis 53716, USA
J Allergy Clin Immunol 128:956-63.e1-7. 2011..The effect on linear growth of daily long-term inhaled corticosteroid therapy in preschool-aged children with recurrent wheezing is controversial...- Submaximal treadmill test predicts VO2max in overweight childrenBlaise A Nemeth
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
J Pediatr 154:677-81. 2009..To demonstrate the ability of a submaximal test to predict VO(2max) in overweight children... - Long-term growth hormone therapy changes the natural history of body composition and motor function in children with prader-willi syndromeAaron L Carrel
Department of Pediatrics, University of Wisconsin, American Family Children s Hospital, 600 Highland Avenue H4 436, Madison, Wisconsin 53792, USA
J Clin Endocrinol Metab 95:1131-6. 2010..The magnitude of these effects suggests that long-term hGH therapy favorably alters the natural history of PWS to an extent that exceeds risks and justifies consideration for initiation during infancy... - Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthmaLeonard B Bacharier
Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63017, USA
J Allergy Clin Immunol 123:1077-82, 1082.e1-5. 2009..However, determination of baseline features associated with ICS responsiveness may identify children most likely to benefit from ICS treatment... - Measuring aerobic cycling power as an assessment of childhood fitnessAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
J Strength Cond Res 21:685-8. 2007..Thus, accurate assessment of childhood aerobic fitness may be achievable by measurement of power, possibly within the school environment at substantially less cost and effort than laboratory-based measurements... - Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthmaNathan Rabinovitch
Department of Pediatrics, National Jewish Health and the University of Colorado Denver School of Medicine, Denver, Colo 80206, USA
J Allergy Clin Immunol 126:545-51.e1-4. 2010..A subset of children with asthma respond better to leukotriene receptor antagonists than to inhaled corticosteroids. Information is needed to identify children with these preferential responses... - Effect of conjugated linoleic acid on body fat accretion in overweight or obese childrenNatalie M Racine
Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI, USA
Am J Clin Nutr 91:1157-64. 2010..Conjugated linoleic acid (CLA) is a supplemental dietary fatty acid that decreases fat mass accretion in young animals... - Fitness level and body composition are associated with inflammation in non-obese childrenJennifer J F McVean
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 54650, USA
J Pediatr Endocrinol Metab 22:153-9. 2009..e., higher levels of CRP). This observation strengthens the importance of promoting both fitness and healthy body composition in all children... - Two years of growth hormone therapy in young children with Prader-Willi syndrome: physical and neurodevelopmental benefitsSusan E Myers
Department of Pediatrics, Saint Louis University, St Louis, Missouri 63104, USA
Am J Med Genet A 143:443-8. 2007..As greater benefits were seen in our study with early treatment, prompt referral to a pediatric endocrinologist for consideration of GH therapy is recommended for PWS at an early age... - Growth hormone improves mobility and body composition in infants and toddlers with Prader-Willi syndromeAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, USA
J Pediatr 145:744-9. 2004..To determine the effect of growth hormone (GH) on body composition and motor development in infants and toddlers with Prader-Willi syndrome (PWS)... - Improvement of fitness, body composition, and insulin sensitivity in overweight children in a school-based exercise program: a randomized, controlled studyAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
Arch Pediatr Adolesc Med 159:963-8. 2005..An effective strategy for prevention and treatment of childhood obesity likely includes a collaborative effort in the school setting... - Inhaled corticosteroids: past lessons and future issuesDavid B Allen
Division of Endocrinology, University of Wisconsin Children's Hospital, Madison 53792-4108, USA
J Allergy Clin Immunol 112:S1-40. 2003.... - School-based fitness changes are lost during the summer vacationAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, 600 Highland Ave, Room H4 436, Madison, WI 53792, USA
Arch Pediatr Adolesc Med 161:561-4. 2007..To determine the changes in percentage of body fat, cardiovascular fitness, and insulin levels during the 3-month summer break in overweight children enrolled in a school-based fitness program... - Benefits of long-term GH therapy in Prader-Willi syndrome: a 4-year studyAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
J Clin Endocrinol Metab 87:1581-5. 2002..Lower doses of GH, (0.3 mg/m(2).d) effective in improving body composition in GHD adults, do not appear to be effective in children with PWS at sustaining improvement in body composition... - Standardized childhood fitness percentiles derived from school-based testingAaron L Carrel
Department of Pediatrics, University of Wisconsin, Madison, WI 53792 4108, USA
J Pediatr 161:120-4. 2012..To develop a statewide school-based program of measuring and reporting cardiovascular fitness levels in children, and to create age- and sex-specific cardiovascular fitness percentile-based distribution curves... - Inhaled corticosteroid therapy for asthma in preschool children: growth issuesDavid B Allen
Department of Pediatrics, Division of Endocrinology, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
Pediatrics 109:373-80. 2002.... - Safety of inhaled corticosteroids in childrenDavid B Allen
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin, USA
Pediatr Pulmonol 33:208-20. 2002..Therefore, these agents should be added to, but should not replace, ICS therapy... - hGH for short stature: ethical issues raised by expanded accessDavid B Allen
Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin 53792-4108, USA
J Pediatr 144:648-52. 2004 - Decreased energy expenditure is caused by abnormal body composition in infants with Prader-Willi SyndromeM Tracy Bekx
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
J Pediatr 143:372-6. 2003..Infants with Prader-Willi syndrome (PWS) are hypotonic and underweight before the onset of childhood obesity. This study evaluates body composition in the PWS infant and its relationship to energy expenditure... - Safety of growth hormone treatment of children with idiopathic short stature: the US experienceDavid B Allen
University of Wisconsin School of Medicine and Public Health and UW American Family Children s Hospital, Madison, Wisc, USA
Horm Res Paediatr 76:45-7. 2011.... - Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezingKatherine Rivera-Spoljaric
Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110 1077, USA
J Pediatr 154:877-81.e4. 2009..To examine parent-reported signs and symptoms as antecedents of wheezing in preschool children with previous moderate to severe wheezing episodes, and to determine the predictive capacity of these symptom patterns for wheezing events... - Systemic effects of inhaled corticosteroids in childrenDavid B Allen
Department of Pediatrics, Pediatric Endocrinology and Pediatric Residency Training, University of Wisconsin Children's Hospital, Madison, Wisconsin 53792, USA
Curr Opin Pediatr 16:440-4. 2004..SUMMARY: Recent studies confirm that benefits of ICS, properly prescribed and used, clearly outweigh not only their potential adverse effects but also the risks associated with poorly controlled asthma... - Childhood obesity and medical neglectTodd Varness
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 4108, USA
Pediatrics 123:399-406. 2009..In these limited cases, a trial of enforced treatment outside the home may be indicated, to protect the child from irreversible harm... - The influence of fitness on insulin resistance in obese childrenAaron L Carrel
Department of Pediatrics, American Family Children s Hospital, University of Wisconsin, Madison, WI 53792, USA
Rev Endocr Metab Disord 10:189-96. 2009..These serve as a strong stimulus for public health strategies to improve fitness in children and adolescents. Methods to assess IR, improve IR and understand complications are increasingly important in children... - Off the growth curve: the challenge of childhood obesityAaron L Carrel
Department of Pediatrics, University of Wisconsin Children s Hospital, 600 Highland Ave H4 436, Madison, WI 53792, USA
WMJ 104:32-7, 69. 2005..This review summarizes appropriate medical evaluation and common sequelae of childhood obesity, and presents a proactive multidiscipline approach to evaluate and treat childhood obesity... - Characteristics of adolescents presenting to a multidisciplinary clinic for polycystic ovarian syndromeM Tracy Bekx
Department of Pediatric Endocrinology, American Family Children s Hospital, Madison, Wisconsin, USA
J Pediatr Adolesc Gynecol 23:7-10. 2010..To characterize patients referred to the adolescent polycystic ovarian syndrome (PCOS) clinic at the American Family Children's Hospital, University of Wisconsin, Madison, Wisconsin... - No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one yearDavid B Allen
University of Wisconsin Children's Hospital, 600 Highland Ave, Madison, Wisconsin 53792, USA
Allergy Asthma Proc 23:407-13. 2002.... - Sex-related differences in immune development and the expression of atopy in early childhoodSara J Uekert
Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA
J Allergy Clin Immunol 118:1375-81. 2006..CLINICAL IMPLICATIONS: The differential expression of atopic diseases between boys and girls in early childhood is accompanied by sex-specific differences in immune response profiles... - Reliable prediction of insulin resistance by a school-based fitness test in middle-school childrenTodd Varness
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 4108, USA
Int J Pediatr Endocrinol 2009:487804. 2009..Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions... - Gender and race influence metabolic benefits of fitness in children: a cross-sectional studyVanessa A Curtis
Department of Pediatrics, University of Iowa Carver College of Medicine, 200 Hawkins Drive, 2859 JPP, Iowa City, IO 52242 1083, USA
Int J Pediatr Endocrinol 2012:4. 2012..abstract:.. - Newborn screening for congenital adrenal hyperplasia has reduced sensitivity in girlsTodd S Varness
Department of Pediatrics, University of Wisconsin Children's Hospital, Madison, Wisconsin 53792-4108, USA
J Pediatr 147:493-8. 2005.... - Respiratory Depression in Young Prader Willi Syndrome Patients following Clonidine Provocation for Growth Hormone Secretion TestingGREGORY A HOLLMAN
American Family Children s Hospital, Department of Pediatrics, University of Wisconsin, Madison, WI 53792, USA
Int J Pediatr Endocrinol 2010:103742. 2010..Conclusions. Clonidine doses to assess GH secretion often exceed doses used for sedation and result in significant respiratory depression in some children with PWS. There was no association between oxygen desaturation and BMI... - Oxandrolone Improves Height Velocity and BMI in Patients with Cystic FibrosisTodd Varness
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 4108, USA
Int J Pediatr Endocrinol 2009:826895. 2009..Larger studies are needed to determine if oxandrolone is an effective, safe, and affordable option to stimulate appetite, improve weight gain, and promote linear growth in patients with CF... - Evaluation of tests of hypothalamic-pituitary-adrenal axis function used to measure effects of inhaled corticosteroidsDavid I Bernstein
Department of Internal Medicine, Division of Immunology Allergy, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
Ann Allergy Asthma Immunol 98:118-27. 2007.... - Inhaled corticosteroids, growth, and complianceOle D Wolthers
N Engl J Med 347:1210-1. 2002 - Sense and sensitivity: assessing inhaled corticosteroid effects on the hypothalamic-pituitary-adrenal axisDavid B Allen
Ann Allergy Asthma Immunol 89:537-9. 2002 - Twenty years of recombinant human growth hormone in children: relevance to pediatric care providersDana S Hardin
Ohio State University and Columbus Children s Hospital, Columbus, OH 43205, USA
Clin Pediatr (Phila) 46:279-86. 2007.... - Long-term inhaled corticosteroids in preschool children at high risk for asthmaTheresa W Guilbert
Division of Pediatric Pulmonary Medicine, Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
N Engl J Med 354:1985-97. 2006..It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma... - Additional sensitivity data for newborn screening for congenital adrenal hyperplasia in WisconsinTodd S Varness
J Pediatr 149:427-8. 2006 - Clinical outcomes and adverse effect monitoring in allergic rhinitisElizabeth F Juniper
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
J Allergy Clin Immunol 115:S390-413. 2005..These considerations have even greater relevance if children are concurrently also receiving inhaled steroids for asthma, because the total steroid load will be greater... - Topical fluticasone propionate lotion does not cause HPA axis suppressionAdelaide A Hebert
Department of Dermatology, University of Texas-Houston Medical School, 6655 Travis Street, Houston, TX 77030, USA
J Pediatr 149:378-82. 2006..These results, together with others from studies using cream and ointment, provide further evidence of the safety of FP...