David B Allen

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Growth hormone therapy for Prader-Willi syndrome: a critical appraisal
    David B Allen
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792 4108, USA
    J Pediatr Endocrinol Metab 17:1297-306. 2004
  2. ncbi request reprint Inhaled steroids for children: effects on growth, bone, and adrenal function
    David B Allen
    University of Wisconsin Children s Hospital, Madison, WI 53792, USA
    Endocrinol Metab Clin North Am 34:555-64, viii. 2005
  3. ncbi request reprint Growth hormone therapy for short stature: is the benefit worth the burden?
    David B Allen
    Department of Pediatrics, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, Wisconsin 53792 4108, USA
    Pediatrics 118:343-8. 2006
  4. ncbi request reprint Effects of inhaled steroids on growth, bone metabolism, and adrenal function
    David B Allen
    University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
    Adv Pediatr 53:101-10. 2006
  5. doi request reprint Growth-attenuation therapy: principles for practice
    David B Allen
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, WI 53792 4108, USA
    Pediatrics 123:1556-61. 2009
  6. ncbi request reprint Effects of inhaled steroids on growth, bone metabolism and adrenal function
    David B Allen
    Professor of Pediatrics, Director of Pediatric Endocrinology and Pediatric Residency Training, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
    Expert Rev Respir Med 1:65-74. 2007
  7. ncbi request reprint Fitness is a stronger predictor of fasting insulin levels than fatness in overweight male middle-school children
    David B Allen
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison 53792, USA
    J Pediatr 150:383-7. 2007
  8. doi request reprint Clinical review: Lessons learned from the hGH era
    David B Allen
    University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    J Clin Endocrinol Metab 96:3042-7. 2011
  9. pmc Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone
    Theresa W Guilbert
    Department of Pediatrics, University of Wisconsin Madison, Wis 53716, USA
    J Allergy Clin Immunol 128:956-63.e1-7. 2011
  10. ncbi request reprint School-based exercise improves fitness, body composition, insulin sensitivity, and markers of inflammation in non-obese children
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792, USA
    J Pediatr Endocrinol Metab 22:409-15. 2009

Detail Information

Publications53

  1. ncbi request reprint Growth hormone therapy for Prader-Willi syndrome: a critical appraisal
    David B Allen
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792 4108, USA
    J Pediatr Endocrinol Metab 17:1297-306. 2004
    ..Consequently, critical evaluation should continue of the long-term benefits, risks, and costs of GH therapy for patients with PWS...
  2. ncbi request reprint Inhaled steroids for children: effects on growth, bone, and adrenal function
    David B Allen
    University of Wisconsin Children s Hospital, Madison, WI 53792, USA
    Endocrinol Metab Clin North Am 34:555-64, viii. 2005
    ..Recent studies confirm that benefits of inhaled corticosteroids outweigh potential adverse effects and the risks associated with poorly controlled asthma...
  3. ncbi request reprint Growth hormone therapy for short stature: is the benefit worth the burden?
    David B Allen
    Department of Pediatrics, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, Wisconsin 53792 4108, USA
    Pediatrics 118:343-8. 2006
  4. ncbi request reprint Effects of inhaled steroids on growth, bone metabolism, and adrenal function
    David B Allen
    University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
    Adv Pediatr 53:101-10. 2006
    ..ICS are highly effective and, because their benefits clearly exceed potential risks, can be used safely in children who have persistent asthma...
  5. doi request reprint Growth-attenuation therapy: principles for practice
    David B Allen
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 448 CSC Pediatrics, 600 Highland Ave, Madison, WI 53792 4108, USA
    Pediatrics 123:1556-61. 2009
    ..Because of the publicity and debate surrounding the first reported case, ethics consultation is recommended...
  6. ncbi request reprint Effects of inhaled steroids on growth, bone metabolism and adrenal function
    David B Allen
    Professor of Pediatrics, Director of Pediatric Endocrinology and Pediatric Residency Training, University of Wisconsin Children s Hospital, H4 448 CSC Pediatrics, 600 Highland Avenue, Madison, WI 53792, USA
    Expert Rev Respir Med 1:65-74. 2007
    ..Overall, however, recent studies confirm that benefits of inhaled corticosteroids, properly prescribed and used, clearly outweigh not only their potential adverse effects, but also the risks associated with poorly controlled asthma...
  7. ncbi request reprint Fitness is a stronger predictor of fasting insulin levels than fatness in overweight male middle-school children
    David B Allen
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison 53792, USA
    J Pediatr 150:383-7. 2007
    ..We studied the relationship between % body fat (%BF), cardiovascular fitness (CVF), and insulin resistance (IR) in overweight middle-school children...
  8. doi request reprint Clinical review: Lessons learned from the hGH era
    David B Allen
    University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    J Clin Endocrinol Metab 96:3042-7. 2011
    ....
  9. pmc Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone
    Theresa W Guilbert
    Department of Pediatrics, University of Wisconsin Madison, Wis 53716, USA
    J Allergy Clin Immunol 128:956-63.e1-7. 2011
    ..The effect on linear growth of daily long-term inhaled corticosteroid therapy in preschool-aged children with recurrent wheezing is controversial...
  10. ncbi request reprint School-based exercise improves fitness, body composition, insulin sensitivity, and markers of inflammation in non-obese children
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792, USA
    J Pediatr Endocrinol Metab 22:409-15. 2009
    ..Whether such a program improves CVF, IR, and other health indicators in non-obese children is unresolved...
  11. doi request reprint Measuring aerobic cycling power as an assessment of childhood fitness
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin, USA
    J Strength Cond Res 22:192-5. 2008
    ..Thus, accurate assessment of childhood aerobic fitness may be achievable by measurement of power, possibly within the school environment, at substantially less cost and effort than laboratory-based measurements...
  12. doi request reprint Submaximal treadmill test predicts VO2max in overweight children
    Blaise A Nemeth
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Pediatr 154:677-81. 2009
    ..To demonstrate the ability of a submaximal test to predict VO(2max) in overweight children...
  13. pmc Long-term growth hormone therapy changes the natural history of body composition and motor function in children with prader-willi syndrome
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin, American Family Children s Hospital, 600 Highland Avenue H4 436, Madison, Wisconsin 53792, USA
    J Clin Endocrinol Metab 95:1131-6. 2010
    ..The magnitude of these effects suggests that long-term hGH therapy favorably alters the natural history of PWS to an extent that exceeds risks and justifies consideration for initiation during infancy...
  14. ncbi request reprint Measuring aerobic cycling power as an assessment of childhood fitness
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
    J Strength Cond Res 21:685-8. 2007
    ..Thus, accurate assessment of childhood aerobic fitness may be achievable by measurement of power, possibly within the school environment at substantially less cost and effort than laboratory-based measurements...
  15. pmc Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma
    Leonard B Bacharier
    Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO 63017, USA
    J Allergy Clin Immunol 123:1077-82, 1082.e1-5. 2009
    ..However, determination of baseline features associated with ICS responsiveness may identify children most likely to benefit from ICS treatment...
  16. ncbi request reprint Fitness level and body composition are associated with inflammation in non-obese children
    Jennifer J F McVean
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 54650, USA
    J Pediatr Endocrinol Metab 22:153-9. 2009
    ..e., higher levels of CRP). This observation strengthens the importance of promoting both fitness and healthy body composition in all children...
  17. pmc Effect of conjugated linoleic acid on body fat accretion in overweight or obese children
    Natalie M Racine
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI, USA
    Am J Clin Nutr 91:1157-64. 2010
    ..Conjugated linoleic acid (CLA) is a supplemental dietary fatty acid that decreases fat mass accretion in young animals...
  18. pmc Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma
    Nathan Rabinovitch
    Department of Pediatrics, National Jewish Health and the University of Colorado Denver School of Medicine, Denver, Colo 80206, USA
    J Allergy Clin Immunol 126:545-51.e1-4. 2010
    ..A subset of children with asthma respond better to leukotriene receptor antagonists than to inhaled corticosteroids. Information is needed to identify children with these preferential responses...
  19. ncbi request reprint Two years of growth hormone therapy in young children with Prader-Willi syndrome: physical and neurodevelopmental benefits
    Susan E Myers
    Department of Pediatrics, Saint Louis University, St Louis, Missouri 63104, USA
    Am J Med Genet A 143:443-8. 2007
    ..As greater benefits were seen in our study with early treatment, prompt referral to a pediatric endocrinologist for consideration of GH therapy is recommended for PWS at an early age...
  20. ncbi request reprint Improvement of fitness, body composition, and insulin sensitivity in overweight children in a school-based exercise program: a randomized, controlled study
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
    Arch Pediatr Adolesc Med 159:963-8. 2005
    ..An effective strategy for prevention and treatment of childhood obesity likely includes a collaborative effort in the school setting...
  21. ncbi request reprint Growth hormone improves mobility and body composition in infants and toddlers with Prader-Willi syndrome
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, USA
    J Pediatr 145:744-9. 2004
    ..To determine the effect of growth hormone (GH) on body composition and motor development in infants and toddlers with Prader-Willi syndrome (PWS)...
  22. ncbi request reprint Inhaled corticosteroids: past lessons and future issues
    David B Allen
    Division of Endocrinology, University of Wisconsin Children s Hospital, Madison 53792 4108, USA
    J Allergy Clin Immunol 112:S1-40. 2003
    ....
  23. ncbi request reprint School-based fitness changes are lost during the summer vacation
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, 600 Highland Ave, Room H4 436, Madison, WI 53792, USA
    Arch Pediatr Adolesc Med 161:561-4. 2007
    ..To determine the changes in percentage of body fat, cardiovascular fitness, and insulin levels during the 3-month summer break in overweight children enrolled in a school-based fitness program...
  24. ncbi request reprint Benefits of long-term GH therapy in Prader-Willi syndrome: a 4-year study
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
    J Clin Endocrinol Metab 87:1581-5. 2002
    ..Lower doses of GH, (0.3 mg/m(2).d) effective in improving body composition in GHD adults, do not appear to be effective in children with PWS at sustaining improvement in body composition...
  25. doi request reprint Long-term effects of recombinant human growth hormone therapy in children with Prader-Willi syndrome
    Peter M Wolfgram
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 4108, USA
    Curr Opin Pediatr 25:509-14. 2013
    ..These benefits must be weighed against potential adverse effects, including rare occurrences of sudden death. This review summarizes recent evidence important to a benefit-risk analysis of hGH use in children with PWS...
  26. pmc Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing
    Katherine Rivera-Spoljaric
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110 1077, USA
    J Pediatr 154:877-81.e4. 2009
    ..To examine parent-reported signs and symptoms as antecedents of wheezing in preschool children with previous moderate to severe wheezing episodes, and to determine the predictive capacity of these symptom patterns for wheezing events...
  27. pmc Standardized childhood fitness percentiles derived from school-based testing
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin, Madison, WI 53792 4108, USA
    J Pediatr 161:120-4. 2012
    ..To develop a statewide school-based program of measuring and reporting cardiovascular fitness levels in children, and to create age- and sex-specific cardiovascular fitness percentile-based distribution curves...
  28. ncbi request reprint Inhaled corticosteroid therapy for asthma in preschool children: growth issues
    David B Allen
    Department of Pediatrics, Division of Endocrinology, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
    Pediatrics 109:373-80. 2002
    ....
  29. ncbi request reprint Safety of inhaled corticosteroids in children
    David B Allen
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin, USA
    Pediatr Pulmonol 33:208-20. 2002
    ..Therefore, these agents should be added to, but should not replace, ICS therapy...
  30. ncbi request reprint Decreased energy expenditure is caused by abnormal body composition in infants with Prader-Willi Syndrome
    M Tracy Bekx
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
    J Pediatr 143:372-6. 2003
    ..Infants with Prader-Willi syndrome (PWS) are hypotonic and underweight before the onset of childhood obesity. This study evaluates body composition in the PWS infant and its relationship to energy expenditure...
  31. ncbi request reprint hGH for short stature: ethical issues raised by expanded access
    David B Allen
    Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin 53792 4108, USA
    J Pediatr 144:648-52. 2004
  32. doi request reprint Safety of growth hormone treatment of children with idiopathic short stature: the US experience
    David B Allen
    University of Wisconsin School of Medicine and Public Health and UW American Family Children s Hospital, Madison, Wisc, USA
    Horm Res Paediatr 76:45-7. 2011
    ....
  33. ncbi request reprint Systemic effects of inhaled corticosteroids in children
    David B Allen
    Department of Pediatrics, Pediatric Endocrinology and Pediatric Residency Training, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792, USA
    Curr Opin Pediatr 16:440-4. 2004
    ..Proper interpretation of ICS safety studies requires knowledge of differences between various ICS drug/delivery device systems...
  34. ncbi request reprint The influence of fitness on insulin resistance in obese children
    Aaron L Carrel
    Department of Pediatrics, American Family Children s Hospital, University of Wisconsin, Madison, WI 53792, USA
    Rev Endocr Metab Disord 10:189-96. 2009
    ..These serve as a strong stimulus for public health strategies to improve fitness in children and adolescents. Methods to assess IR, improve IR and understand complications are increasingly important in children...
  35. pmc Childhood obesity and medical neglect
    Todd Varness
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 4108, USA
    Pediatrics 123:399-406. 2009
    ..In these limited cases, a trial of enforced treatment outside the home may be indicated, to protect the child from irreversible harm...
  36. pmc Ethnic differences in the effects of hepatic fat deposition on insulin resistance in nonobese middle school girls
    Peter M Wolfgram
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
    Obesity (Silver Spring) 22:243-8. 2014
    ..In nonobese youth, to investigate whether hepatic fat deposition and its metabolic consequences vary between ethnic groups...
  37. ncbi request reprint Off the growth curve: the challenge of childhood obesity
    Aaron L Carrel
    Department of Pediatrics, University of Wisconsin Children s Hospital, 600 Highland Ave H4 436, Madison, WI 53792, USA
    WMJ 104:32-7, 69. 2005
    ..This review summarizes appropriate medical evaluation and common sequelae of childhood obesity, and presents a proactive multidiscipline approach to evaluate and treat childhood obesity...
  38. doi request reprint Characteristics of adolescents presenting to a multidisciplinary clinic for polycystic ovarian syndrome
    M Tracy Bekx
    Department of Pediatric Endocrinology, American Family Children s Hospital, Madison, Wisconsin, USA
    J Pediatr Adolesc Gynecol 23:7-10. 2010
    ..To characterize patients referred to the adolescent polycystic ovarian syndrome (PCOS) clinic at the American Family Children's Hospital, University of Wisconsin, Madison, Wisconsin...
  39. pmc Reliable prediction of insulin resistance by a school-based fitness test in middle-school children
    Todd Varness
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 4108, USA
    Int J Pediatr Endocrinol 2009:487804. 2009
    ..Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions...
  40. ncbi request reprint No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year
    David B Allen
    University of Wisconsin Children s Hospital, 600 Highland Ave, Madison, Wisconsin 53792, USA
    Allergy Asthma Proc 23:407-13. 2002
    ....
  41. ncbi request reprint Sex-related differences in immune development and the expression of atopy in early childhood
    Sara J Uekert
    Department of Pediatrics, University of Wisconsin Madison, Madison, WI, USA
    J Allergy Clin Immunol 118:1375-81. 2006
    ..Sex and age are known to influence the clinical expression of asthma and allergic diseases...
  42. pmc Gender and race influence metabolic benefits of fitness in children: a cross-sectional study
    Vanessa A Curtis
    Department of Pediatrics, University of Iowa Carver College of Medicine, 200 Hawkins Drive, 2859 JPP, Iowa City, IO 52242 1083, USA
    Int J Pediatr Endocrinol 2012:4. 2012
    ..abstract:..
  43. pmc Respiratory Depression in Young Prader Willi Syndrome Patients following Clonidine Provocation for Growth Hormone Secretion Testing
    GREGORY A HOLLMAN
    American Family Children s Hospital, Department of Pediatrics, University of Wisconsin, Madison, WI 53792, USA
    Int J Pediatr Endocrinol 2010:103742. 2010
    ..Conclusions. Clonidine doses to assess GH secretion often exceed doses used for sedation and result in significant respiratory depression in some children with PWS. There was no association between oxygen desaturation and BMI...
  44. ncbi request reprint Newborn screening for congenital adrenal hyperplasia has reduced sensitivity in girls
    Todd S Varness
    Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, Wisconsin 53792 4108, USA
    J Pediatr 147:493-8. 2005
    ....
  45. pmc Oxandrolone Improves Height Velocity and BMI in Patients with Cystic Fibrosis
    Todd Varness
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, H4 4 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 4108, USA
    Int J Pediatr Endocrinol 2009:826895. 2009
    ..Larger studies are needed to determine if oxandrolone is an effective, safe, and affordable option to stimulate appetite, improve weight gain, and promote linear growth in patients with CF...
  46. ncbi request reprint Evaluation of tests of hypothalamic-pituitary-adrenal axis function used to measure effects of inhaled corticosteroids
    David I Bernstein
    Department of Internal Medicine, Division of Immunology Allergy, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 98:118-27. 2007
    ....
  47. ncbi request reprint Twenty years of recombinant human growth hormone in children: relevance to pediatric care providers
    Dana S Hardin
    Ohio State University and Columbus Children s Hospital, Columbus, OH 43205, USA
    Clin Pediatr (Phila) 46:279-86. 2007
    ....
  48. ncbi request reprint Sense and sensitivity: assessing inhaled corticosteroid effects on the hypothalamic-pituitary-adrenal axis
    David B Allen
    Ann Allergy Asthma Immunol 89:537-9. 2002
  49. ncbi request reprint Long-term inhaled corticosteroids in preschool children at high risk for asthma
    Theresa W Guilbert
    Division of Pediatric Pulmonary Medicine, Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
    N Engl J Med 354:1985-97. 2006
    ..It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma...
  50. ncbi request reprint Inhaled corticosteroids, growth, and compliance
    Ole D Wolthers
    N Engl J Med 347:1210-1. 2002
  51. ncbi request reprint Clinical outcomes and adverse effect monitoring in allergic rhinitis
    Elizabeth F Juniper
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
    J Allergy Clin Immunol 115:S390-413. 2005
    ..These considerations have even greater relevance if children are concurrently also receiving inhaled steroids for asthma, because the total steroid load will be greater...
  52. ncbi request reprint Additional sensitivity data for newborn screening for congenital adrenal hyperplasia in Wisconsin
    Todd S Varness
    J Pediatr 149:427-8. 2006
  53. ncbi request reprint Topical fluticasone propionate lotion does not cause HPA axis suppression
    Adelaide A Hebert
    Department of Dermatology, University of Texas Houston Medical School, 6655 Travis Street, Houston, TX 77030, USA
    J Pediatr 149:378-82. 2006
    ..To establish the absence of adrenal suppression of fluticasone propionate (FP) 0.05% lotion when applied extensively to children (3 months to 6 years), with moderate to severe atopic dermatitis (AD)...