Christopher D C Allen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, 513 Parnassus Avenue, Box 0414, University of California, San Francisco, CA 94143 0414, USA
    Semin Immunol 20:14-25. 2008
  2. ncbi Germinal-center organization and cellular dynamics
    Christopher D C Allen
    Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
    Immunity 27:190-202. 2007
  3. ncbi Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
    Nicole M Haynes
    Howard Hughes Medical Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 179:5099-108. 2007
  4. ncbi Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition
    Zhiyong Yang
    Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 36:857-72. 2012
  5. ncbi Imaging of germinal center selection events during affinity maturation
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Science 315:528-31. 2007
  6. ncbi Genetic analysis of basophil function in vivo
    Brandon M Sullivan
    Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California, USA
    Nat Immunol 12:527-35. 2011
  7. ncbi TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
    Thomas T Chen
    Veterans Administration Medical Center, San Francisco, CA 94121, USA
    J Exp Med 202:955-65. 2005
  8. ncbi The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement
    Jesse A Green
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, San Francisco, California, USA
    Nat Immunol 12:672-80. 2011
  9. ncbi MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells
    David F Steiner
    Sandler Asthma Basic Research Center and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 35:169-81. 2011
  10. ncbi Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143 0414, USA
    Nat Immunol 5:943-52. 2004

Collaborators

Detail Information

Publications10

  1. ncbi Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, 513 Parnassus Avenue, Box 0414, University of California, San Francisco, CA 94143 0414, USA
    Semin Immunol 20:14-25. 2008
    ..We will then discuss current understanding of how they help support the B cell immune response...
  2. ncbi Germinal-center organization and cellular dynamics
    Christopher D C Allen
    Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
    Immunity 27:190-202. 2007
    ....
  3. ncbi Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
    Nicole M Haynes
    Howard Hughes Medical Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 179:5099-108. 2007
    ....
  4. ncbi Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition
    Zhiyong Yang
    Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 36:857-72. 2012
    ..Most IgE(+) PCs were short lived and showed reduced affinity maturation, revealing intrinsic mechanisms that restrict the IgE antibody response...
  5. ncbi Imaging of germinal center selection events during affinity maturation
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Science 315:528-31. 2007
    ..On the basis of these observations, we propose a model in which competition for T cell help plays a more dominant role in the selection of GC B cells than previously appreciated...
  6. ncbi Genetic analysis of basophil function in vivo
    Brandon M Sullivan
    Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California, USA
    Nat Immunol 12:527-35. 2011
    ..Although targeted deletion of IL-4 and IL-13 in either CD4(+) T cells or basophils had a minimal effect on worm clearance, deletion from both lineages demonstrated a nonredundant role for basophil cytokines in primary helminth immunity...
  7. ncbi TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
    Thomas T Chen
    Veterans Administration Medical Center, San Francisco, CA 94121, USA
    J Exp Med 202:955-65. 2005
    ..This is the first identification of a receptor for ferritin and reveals a new role for TIM-2...
  8. ncbi The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement
    Jesse A Green
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, San Francisco, California, USA
    Nat Immunol 12:672-80. 2011
    ..We suggest that by inhibiting Akt activation and migration, S1P(2) helps restrict GC B cell survival and localization to an S1P-low niche at the follicle center...
  9. ncbi MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells
    David F Steiner
    Sandler Asthma Basic Research Center and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
    Immunity 35:169-81. 2011
    ..These results demonstrate that miR-29 regulates helper T cell differentiation by repressing multiple target genes, including at least two that are independently capable of inducing the T helper 1 (Th1) cell gene expression program...
  10. ncbi Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5
    Christopher D C Allen
    Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143 0414, USA
    Nat Immunol 5:943-52. 2004
    ..In contrast, CXCR5 helped direct cells to the light zone and deficiency in CXCL13 was associated with aberrant light zone localization...