Research Topics
| James M AlexanderSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Hypertensive emergencies of pregnancyJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9032, USA
Obstet Gynecol Clin North Am 40:89-101. 2013..Immediate stabilization of the mother including the use of intervenous antihypertensives is required and often delivery is indicated. With appropriate management, maternal and fetal outcomes can be excellent...- Intrapartum hemorrhageJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9032, USA
Obstet Gynecol Clin North Am 40:15-26. 2013..Prompt recognition of blood loss, identification of the source of the hemorrhage, volume resuscitation, including red blood cells and blood products when required, will result in excellent maternal outcomes... 
Comparison of maternal and infant outcomes from primary cesarean delivery during the second compared with first stage of laborJames M Alexander
Department of Obstetrics and Gynecology at the University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
Obstet Gynecol 109:917-21. 2007..To compare maternal and neonatal outcomes when primary cesarean delivery is performed in the second stage of labor compared with the first stage...
Cesarean delivery for the second twinJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235 9032, USA
Obstet Gynecol 112:748-52. 2008..To examine maternal and infant outcomes after a vaginal delivery of twin A and a cesarean delivery of twin B, and to identify whether the second twin experienced increased short-term morbidity as part of a combined route of delivery...- Whole blood in the management of hypovolemia due to obstetric hemorrhageJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
Obstet Gynecol 113:1320-6. 2009..To study the use of blood products including whole blood, for the management of obstetric hemorrhage requiring transfusion... - Failed operative vaginal deliveryJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Obstet Gynecol 114:1017-22. 2009..To compare maternal and neonatal outcomes in women undergoing second-stage cesarean delivery after a trial of operative vaginal delivery with those in women undergoing second-stage cesarean delivery without such an attempt... - Epidural analgesia lengthens the Friedman active phase of laborJames M Alexander
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 75390 9032, USA
Obstet Gynecol 100:46-50. 2002..To estimate the effect of epidural analgesia on the Friedman labor curve... - Fetal injury associated with cesarean deliveryJames M Alexander
Department of Obstetrics at the University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
Obstet Gynecol 108:885-90. 2006..To describe the incidence and type of fetal injury identified in women undergoing cesarean delivery... - An analysis of second-stage labor beyond 3 hours in nulliparous womenApril T Bleich
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9032, USA
Am J Perinatol 29:717-22. 2012..To analyze outcomes after second-stage labor beyond 3 hours and determine if prolonged second stages were intentional... - Inhibin-A and superimposed preeclampsia in women with chronic hypertensionGerda G Zeeman
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
Obstet Gynecol 101:232-6. 2003..To determine if maternal serum inhibin-A can be used as a marker for subsequent development of superimposed preeclampsia in women with chronic hypertension... - Cesarean delivery: a randomized trial of epidural analgesia versus intravenous meperidine analgesia during labor in nulliparous womenShiv K Sharma
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9068, USA
Anesthesiology 96:546-51. 2002.... - Defining uterine tachysystole: how much is too much?Robert D Stewart
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9032, USA
Am J Obstet Gynecol 207:290.e1-6. 2012..We sought to determine if uterine tachysystole, ≥ 6 contractions per 10 minutes, within the first 4 hours of labor induction, is associated with adverse infant outcomes... - Calculated blood loss in severe obstetric hemorrhage and its relation to body mass indexJennifer S Hernandez
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, 75235 9032, USA
Am J Perinatol 29:557-60. 2012..To evaluate total calculated blood loss at the time of severe obstetric hemorrhage... - Determining cervical ripeness and labor outcome: the efficacy of magnetic resonance T2 relaxation timesJason A Pates
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 323 Harry Hines Boulevard, Dallas, TX 75235, USA
Obstet Gynecol 109:326-30. 2007.... - Oral misoprostol for labor augmentation: a randomized controlled trialApril T Bleich
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9032, USA
Obstet Gynecol 118:1255-60. 2011..To estimate the efficacy of oral misoprostol for labor augmentation... - The significance of antiphospholipid antibodies in pregnant women with chronic hypertensionGerda G Zeeman
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
Am J Perinatol 21:275-9. 2004..The significance of such antibodies in this particular group of patients can only be resolved with a large multicenter study... - A comparison of the effects of epidural and meperidine analgesia during labor on fetal heart rateJames B Hill
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9032, USA
Obstet Gynecol 102:333-7. 2003..To estimate the effects of initiation of epidural analgesia on fetal heart rate (FHR) patterns compared with intravenous meperidine analgesia... - Ruptured membranes at term: randomized, double-blind trial of oral misoprostol for labor inductionJulie Y Lo
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235 9032, USA
Obstet Gynecol 101:685-9. 2003..To determine if oral misoprostol can replace oxytocin for labor stimulation in women with ruptured membranes at term and without evidence of labor... - A randomized trial of birthing with and without stirrupsMarlene M Corton
Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, USA
Am J Obstet Gynecol 207:133.e1-5. 2012..The objective of the study was to determine whether bed delivery without stirrups reduces the incidence of perineal lacerations compared with delivery in stirrups... - Homocysteine plasma concentration levels for the prediction of preeclampsia in women with chronic hypertensionGerda G Zeeman
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Am J Obstet Gynecol 189:574-6. 2003..The purpose of this study was to evaluate prospectively midtrimester homocysteine concentration levels for the prediction of superimposed preeclampsia in women with chronic hypertension... - A dose-finding study of oral misoprostol for labor augmentationKathryn S Villano
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, USA
Am J Obstet Gynecol 204:560.e1-5. 2011..We designed a dose-finding trial of oral misoprostol administered for labor augmentation... - Selective magnesium sulfate prophylaxis for the prevention of eclampsia in women with gestational hypertensionJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75235-9032, USA
Obstet Gynecol 108:826-32. 2006..level of evidence: ii-3... - Magnetic resonance imaging pelvimetry and the prediction of labor dystociaMichael V Zaretsky
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235-9032, USA
Obstet Gynecol 106:919-26. 2005..CONCLUSION: We found significant associations with MRI pelvimetry and labor dystocia, but MRI was not a significant improvement over previously described pelvimetric techniques. LEVEL OF EVIDENCE: II-3... - Effect of maternal body mass index on serum magnesium levels given for seizure prophylaxisCarmen M Tudela
University of Texas Southwestern Medical Center, Department of Obstetrics and Gynecology, Dallas, Texas 75390 9032, USA
Obstet Gynecol 121:314-20. 2013..To estimate the effect of body mass index (BMI) on magnesium levels for eclampsia prophylaxis... - Timing of birth after spontaneous onset of laborPeggy J Mancuso
College of Nursing, Texas Woman's University and the Department of Obstetrics and Gynecology, UT Southwestern Medical Center, Dallas, Texas, USA
Obstet Gynecol 103:653-6. 2004..There is no natural association between spontaneous birth in low-risk women and the day of the week. LEVEL OF EVIDENCE: II-2.. - Ultrasonographic cervical length and risk of hemorrhage in pregnancies with placenta previaIrene A Stafford
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Obstet Gynecol 116:595-600. 2010..To estimate the relationship between cervical length and hemorrhage leading to preterm delivery in women with placenta previa... - Transfer of inflammatory cytokines across the placentaMichael V Zaretsky
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9032, USA
Obstet Gynecol 103:546-50. 2004..The purpose of this study was to determine whether the placental transfer of interleukin (IL)-1alpha, IL-6, and tumor necrosis factor-alpha (TNF-alpha) occurs... - Inhibin-A levels and severity of hypertensive disorders due to pregnancyGerda G Zeeman
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 75390 9032, USA
Obstet Gynecol 100:140-4. 2002..To evaluate the use of 3rd trimester inhibin-A levels as an adjunct to assess severity of hypertensive disorders due to pregnancy in women evaluated for preeclampsia... - Effects of magnesium sulfate on preterm fetal cerebral blood flow using Doppler analysis: a randomized controlled trialDiane M Twickler
University of Texas Southwestern Medical Center, Departments of Radiology and Obstetrics and Gynecology, Dallas, Texas 75235 9032, USA
Obstet Gynecol 115:21-5. 2010..To estimate the effects of maternal administration of magnesium sulfate on the fetal middle cerebral artery using Doppler... - Risk of hepatitis B transmission in breast-fed infants of chronic hepatitis B carriersJames B Hill
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 75235 9032, USA
Obstet Gynecol 99:1049-52. 2002..To measure the rate of hepatitis B (HBV) transmission from chronic HBV carriers to breast-fed infants after immunoprophylaxis... - Appearance of the levator ani muscle in pregnancy as assessed by 3-D MRIMuriel K Boreham
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Am J Obstet Gynecol 193:2159-64. 2005..CONCLUSION: BMI was correlated with LA volume in postterm nulliparas. LA insertion into the symphysis and the iliococcygeus arch were well-preserved overall and morphometry was variable... - Neonatal effects of magnesium sulfate given to the motherMina Abbassi-Ghanavati
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas
Am J Perinatol 29:795-800. 2012..Conclusion Several neonatal complications are significantly related to increasing concentrations of magnesium in the maternal circulation... - Urine screening for Chlamydia trachomatis during pregnancyScott W Roberts
Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas 75235 9032, USA
Obstet Gynecol 117:883-5. 2011..To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution... - Epidural analgesia for labor pain and its relationship to feverJames M Alexander
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9032, USA
Clin Perinatol 32:777-87. 2005..Thus it seems unreasonable to avoid labor epidurals due to the risk of fever. Epidural analgesia remains one of the most effective forms of pain relief in labor and is a reasonable option for most women... - Seizures and intracranial hemorrhageKaren L Wilson
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Obstet Gynecol Clin North Am 40:103-20. 2013..This article also highlights some challenging management issues from the obstetrician's perspective... - Placenta accreta, increta, and percretaAlison C Wortman
Department of Maternal Fetal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Obstet Gynecol Clin North Am 40:137-54. 2013..Referral to a tertiary care center and the use of a multidisciplinary care team is recommended... - Umbilical vein interleukin-6 levels correlate with the severity of placental inflammation and gestational ageBeverly Barton Rogers
Department of Pathology, The University of Texas Southwestern Medical School, Dallas, TX, USA
Hum Pathol 33:335-40. 2002..In conclusion, umbilical venous IL6 levels correlate with the severity of acute placental inflammation, with greater IL6 elevations in term infants compared to preterm infants until the inflammation becomes severe... - Oxytocin preparation stability in several common obstetric intravenous solutionsJohn W Gard
Pharmacy Services Parkland Health and Hospital Systems and the Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235, USA
Am J Obstet Gynecol 186:496-8. 2002..The purpose of this study was to determine the stability of oxytocin in lactated Ringer's solution and lactated Ringer's-dextrose 5% solution over a 24-hour period at 25 degrees C and over a 7-day period at 5 degrees C... - A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsyDwight J Rouse
University of Alabama at Birmingham, Birmingham, USA
N Engl J Med 359:895-905. 2008..Research suggests that fetal exposure to magnesium sulfate before preterm birth might reduce the risk of cerebral palsy...