Andrew Alexander

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Characterization of cerebral white matter properties using quantitative magnetic resonance imaging stains
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53705, USA
    Brain Connect 1:423-46. 2011
  2. pmc Diffusion tensor imaging of the brain
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Neurotherapeutics 4:316-29. 2007
  3. ncbi request reprint Comparison of diffusion tensor imaging measurements at 3.0 T versus 1.5 T with and without parallel imaging
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, WI 53706, USA
    Neuroimaging Clin N Am 16:299-309, xi. 2006
  4. ncbi request reprint Diffusion tensor imaging of the corpus callosum in Autism
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, WI, USA
    Neuroimage 34:61-73. 2007
  5. doi request reprint An experimental evaluation of diffusion tensor image segmentation using graph-cuts
    Deok Han
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, WI, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5653-6. 2009
  6. ncbi request reprint Amygdala volume and nonverbal social impairment in adolescent and adult males with autism
    Brendon M Nacewicz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Waisman Center, 1500 Highland Avenue, Madison, WI 53705, USA
    Arch Gen Psychiatry 63:1417-28. 2006
  7. ncbi request reprint Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns
    Brian J Jellison
    Department of Radiology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, E3 311 CSC, Madison, WI 53792 3252, USA
    AJNR Am J Neuroradiol 25:356-69. 2004
  8. ncbi request reprint Investigation of anomalous estimates of tensor-derived quantities in diffusion tensor imaging
    Cheng Guan Koay
    Department of Physics, University of Wisconsin Madison, Madison, Wisconsin, USA
    Magn Reson Med 55:930-6. 2006
  9. ncbi request reprint Quantitative analysis of diffusion tensor orientation: theoretical framework
    Yu Chien Wu
    Department of Medical Physics, University of Wisconsin, Madison 53705, USA
    Magn Reson Med 52:1146-55. 2004
  10. ncbi request reprint Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI, United States
    Neurosci Lett 424:127-32. 2007

Research Grants

  1. DIFFUSION MRI OF THE HUMAN BRAIN
    Andrew Alexander; Fiscal Year: 2003
  2. Structural & Functional Measures of Brain Development
    Andrew Alexander; Fiscal Year: 2004
  3. DIFFUSION MRI OF THE HUMAN BRAIN
    Andrew Alexander; Fiscal Year: 2007

Detail Information

Publications58

  1. pmc Characterization of cerebral white matter properties using quantitative magnetic resonance imaging stains
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53705, USA
    Brain Connect 1:423-46. 2011
    ..This article provides an overview of the qMRI stain mechanisms, acquisition and analysis strategies, and applications for these qMRI stains...
  2. pmc Diffusion tensor imaging of the brain
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Neurotherapeutics 4:316-29. 2007
    ..g., radial or axial). To maximize the specificity and better characterize the tissue microstructure, future studies should use multiple diffusion tensor measures (e.g., MD and FA, or D(a) and D(r))...
  3. ncbi request reprint Comparison of diffusion tensor imaging measurements at 3.0 T versus 1.5 T with and without parallel imaging
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, WI 53706, USA
    Neuroimaging Clin N Am 16:299-309, xi. 2006
    ..5 T to 3.0 T, but was reduced by 50% when using parallel imaging. In summary, DTI studies at 3.0 T using parallel imaging will provide significantly improved DTI measurements relative to studies at 1.5 T...
  4. ncbi request reprint Diffusion tensor imaging of the corpus callosum in Autism
    Andrew L Alexander
    Department of Medical Physics, University of Wisconsin, Madison, WI, USA
    Neuroimage 34:61-73. 2007
    ..These results suggest that the microstructure of the corpus callosum is affected in autism, which may be related to nonverbal cognitive performance...
  5. doi request reprint An experimental evaluation of diffusion tensor image segmentation using graph-cuts
    Deok Han
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, WI, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5653-6. 2009
    ..Overall, the graph cuts method performed well, giving an average segmentation accuracy of about 0.90, 0.77 and 0.88 for WM, GM and CSF respectively in terms of volume overlap(VO)...
  6. ncbi request reprint Amygdala volume and nonverbal social impairment in adolescent and adult males with autism
    Brendon M Nacewicz
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Waisman Center, 1500 Highland Avenue, Madison, WI 53705, USA
    Arch Gen Psychiatry 63:1417-28. 2006
    ..Autism is a syndrome of unknown cause, marked by abnormal development of social behavior. Attempts to link pathological features of the amygdala, which plays a key role in emotional processing, to autism have shown little consensus...
  7. ncbi request reprint Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns
    Brian J Jellison
    Department of Radiology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, E3 311 CSC, Madison, WI 53792 3252, USA
    AJNR Am J Neuroradiol 25:356-69. 2004
  8. ncbi request reprint Investigation of anomalous estimates of tensor-derived quantities in diffusion tensor imaging
    Cheng Guan Koay
    Department of Physics, University of Wisconsin Madison, Madison, Wisconsin, USA
    Magn Reson Med 55:930-6. 2006
    ..Simulation results show that the CNLS method is, in terms of mean squared error for estimating trace and FA, the most effective method for correcting negative eigenvalues...
  9. ncbi request reprint Quantitative analysis of diffusion tensor orientation: theoretical framework
    Yu Chien Wu
    Department of Medical Physics, University of Wisconsin, Madison 53705, USA
    Magn Reson Med 52:1146-55. 2004
    ..This novel approach distills the rich, 3D information available from the diffusion tensor into a form that lends itself to quantitative analysis and statistical hypothesis testing...
  10. ncbi request reprint Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI, United States
    Neurosci Lett 424:127-32. 2007
    ..These results suggest that white matter microstructure in autism is abnormal in these temporal lobe regions, which is consistent with theories of aberrant brain connectivity in autism...
  11. ncbi request reprint Contextual modulation of amygdala responsivity to surprised faces
    Hackjin Kim
    University of Wisconsin Madison, Madison, WI 53705, USA
    J Cogn Neurosci 16:1730-45. 2004
    ..Connectivity analyses identified candidate cortical-subcortical systems subserving this modulation...
  12. ncbi request reprint Repetitive transcranial magnetic stimulation dissociates working memory manipulation from retention functions in the prefrontal, but not posterior parietal, cortex
    Bradley R Postle
    University of Wisconsin, USA
    J Cogn Neurosci 18:1712-22. 2006
    ..In the SPL, they illustrate the importance of supplementing the fundamentally correlational data from neuroimaging with a disruptive method, which affords stronger inference about structure-function relations...
  13. pmc Intraoperative intracerebral MRI-guided navigation for accurate targeting in nonhuman primates
    Marina E Emborg
    Preclinical Parkinson s Research Program, Wisconsin National Primate Research Center, University of Wisconsin Madison, 1223 Capitol Court, Madison, WI 53715, USA
    Cell Transplant 19:1587-97. 2010
    ..5 mm. Our results in nonhuman primates confirm the accuracy of intraoperative MRI intracerebral navigation combined with an adaptable, pivot point-based targeting system and validates its use for preclinical intracerebral procedures...
  14. ncbi request reprint Gaze fixations predict brain activation during the voluntary regulation of picture-induced negative affect
    Carien M van Reekum
    Laboratory for Affective Neuroscience, Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 36:1041-55. 2007
    ..Furthermore, this variation in gaze fixation accounted for substantial amounts of variance in brain activation. These data point to the importance of controlling for gaze fixation in studies of emotion regulation that use visual stimuli...
  15. pmc Hybrid diffusion imaging
    Yu Chien Wu
    Department of Radiology, University of Wisconsin Madison, Madison, WI, USA
    Neuroimage 36:617-29. 2007
    ..In this study, an HYDI encoding scheme with 102 diffusion-weighted measurements was obtained over most of the human cerebrum in under 30 min...
  16. ncbi request reprint Gaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism
    Kim M Dalton
    Waisman Center, University of Wisconsin, Madison, Wisconsin, USA
    Biol Psychiatry 61:512-20. 2007
    ..These characteristics primarily affect the social aspects of language, communication, and human interaction. The current research focuses on possible neurobehavioral characteristics associated with the broad autism phenotype...
  17. ncbi request reprint Individual differences in amygdala and ventromedial prefrontal cortex activity are associated with evaluation speed and psychological well-being
    Carien M van Reekum
    University of Wisconsin Madison, Madison, WI 52706, USA
    J Cogn Neurosci 19:237-48. 2007
    ....
  18. pmc A method for calibrating diffusion gradients in diffusion tensor imaging
    Yu Chien Wu
    Department of Radiology, University of Wisconsin Madison, Madison, WI, USA
    J Comput Assist Tomogr 31:984-93. 2007
    ..To calibrate and correct the gradient errors including gradient amplitude scaling errors, background/imaging gradients, and residual gradients in diffusion tensor imaging (DTI)...
  19. pmc Effect of Alzheimer disease risk on brain function during self-appraisal in healthy middle-aged adults
    Sterling C Johnson
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA
    Arch Gen Psychiatry 64:1163-71. 2007
    ....
  20. pmc White matter is altered with parental family history of Alzheimer's disease
    Barbara B Bendlin
    Geriatric Research Educational and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
    Alzheimers Dement 6:394-403. 2010
    ..We examined the main effects of family history and APOE varepsilon4 on brain integrity, in addition to assessing possible additive effects of these two risk factors...
  21. pmc White matter in aging and cognition: a cross-sectional study of microstructure in adults aged eighteen to eighty-three
    Barbara B Bendlin
    Geriatric Research Educational and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
    Dev Neuropsychol 35:257-77. 2010
    ..The complex relationships between cognition, white matter microstructure, and white matter volume still require further investigation...
  22. doi request reprint Classification in DTI using shapes of white matter tracts
    Nagesh Adluru
    Dept of Psychology, Brigham Young Univ, UT, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:2719-22. 2009
    ....
  23. pmc A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI 53705, USA
    Neuroimage 44:870-83. 2009
    ..The T-SPOON method may be also applicable to other quantitative imaging maps such as T1 or T2 relaxometry, magnetization transfer, or PET tracer maps...
  24. pmc Computation of diffusion function measures in q-space using magnetic resonance hybrid diffusion imaging
    Yu Chien Wu
    Department of Radiology, University of Wisconsin Madison, 600 Highland Ave, Madison, WI 53792, USA
    IEEE Trans Med Imaging 27:858-65. 2008
    ..Although this study focused on data using the HYDI scheme, this computation approach may be applied to other diffusion sampling schemes including Cartesian diffusion spectrum imaging...
  25. pmc Automatic physiological waveform processing for FMRI noise correction and analysis
    Daniel J Kelley
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, University of Wisconsin, Madison, Wisconsin, United States of America
    PLoS ONE 3:e1751. 2008
    ..PhysioNoise consistently identifies physiological fluctuations for fMRI noise correction and also generates covariates for subsequent analyses of brain activation and connectivity...
  26. pmc Creating physical 3D stereolithograph models of brain and skull
    Daniel J Kelley
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, Wisconsin, United States of America
    PLoS ONE 2:e1119. 2007
    ..Compared to 2D images, VR and stereolithograph models provide an extra dimension that enhances both the quality of visual information and utility of surface visualization in neuroscience and medicine...
  27. ncbi request reprint Hybrid diffusion imaging (HYDI)
    Andrew L Alexander
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53705, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2245-8. 2006
    ..HYDI experiments were performed on the brains of healthy volunteers and the results are presented. Overall, HYDI is an efficient and promising method for characterizing complex diffusion in the human brain and potentially other tissues...
  28. pmc The cerebral response during subjective choice with and without self-reference
    Sterling C Johnson
    William S Middleton VA Medical Center, Madison, WI 53705, USA
    J Cogn Neurosci 17:1897-906. 2005
    ..The findings suggest that self-referential processing, rather than subjective judgments among ambiguous response alternatives, accounted for the AMPFC and RSC response...
  29. ncbi request reprint Bootstrap white matter tractography (BOOT-TRAC)
    Mariana Lazar
    WM Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, Madison, WI 53705, USA
    Neuroimage 24:524-32. 2005
    ..The approach was used to generate probabilistic connectivity maps between the cerebral peduncles and specific cortical regions...
  30. ncbi request reprint An error analysis of white matter tractography methods: synthetic diffusion tensor field simulations
    Mariana Lazar
    Department of Physics, University of Utah, Salt Lake City, UT 84112, USA
    Neuroimage 20:1140-53. 2003
    ..These models may be used in future studies to assess the level of confidence associated with a tractography result...
  31. doi request reprint Efficient parametric encoding scheme for white matter fiber bundles
    Moo K Chung
    Waisman Laboratory for Brain Imaging and Behavior at the University of Wisconsin, Madison, WI, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6644-7. 2009
    ..As an illustration, we apply the proposed method in characterizing abnormal tracts that pass through the splenium of the corpus callosum in autistic subjects...
  32. ncbi request reprint Less white matter concentration in autism: 2D voxel-based morphometry
    Moo K Chung
    Department of Statistics, University of Wisconsin Madison, Madison, WI 53706, USA
    Neuroimage 23:242-51. 2004
    ..Further, it is shown that the less white matter concentration in the corpus callosum in autism is due to hypoplasia rather than atrophy...
  33. ncbi request reprint Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumor
    Aaron S Field
    Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792 3252, USA
    J Magn Reson Imaging 20:555-62. 2004
    ..To categorize the varied appearances of tumor-altered white matter (WM) tracts on diffusion tensor eigenvector directional color maps...
  34. ncbi request reprint Diffusion tensor imaging in cerebral tumor diagnosis and therapy
    Aaron S Field
    Departments of Radiology and Biomedical Engineering, University of Wisconsin, Madison, WI, USA
    Top Magn Reson Imaging 15:315-24. 2004
    ....
  35. ncbi request reprint Gaze fixation and the neural circuitry of face processing in autism
    Kim M Dalton
    Waisman Center, University of Wisconsin, 1500 Highland Avenue, Madison, Wisconsin 53705 2280, USA
    Nat Neurosci 8:519-26. 2005
    ..In addition, variation in eye fixation within autistic individuals was strongly and positively associated with amygdala activation across both studies, suggesting a heightened emotional response associated with gaze fixation in autism...
  36. ncbi request reprint Stability of amygdala BOLD response to fearful faces over multiple scan sessions
    Tom Johnstone
    W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, WI 53705, USA
    Neuroimage 25:1112-23. 2005
    ..Future studies might manipulate the experimental design to either amplify or attenuate this variability, according to the goals of the research...
  37. ncbi request reprint Cortical thickness analysis in autism with heat kernel smoothing
    Moo K Chung
    Department of Statistics, University of Wisconsin, 1210 West Dayton Street, Madison, WI 53706, USA
    Neuroimage 25:1256-65. 2005
    ..As an illustration, we apply our methods in detecting the regions of abnormal cortical thickness in 16 high functioning autistic children via random field based multiple comparison correction that utilizes the new smoothing technique...
  38. ncbi request reprint Axial asymmetry of water diffusion in brain white matter
    Mariana Lazar
    W M Keck Laboratory for Functional Brain Imaging and Behavior, Madison, WI 53705, USA
    Magn Reson Med 54:860-7. 2005
    ..This study shows that WM axial asymmetry causes anisotropic dispersion patterns in the estimated tract trajectories. The medium and minor eigenvector patterns may be useful for elucidating the local dispersion distributions of WM tracts...
  39. ncbi request reprint Generation and visualization of four-dimensional MR angiography data using an undersampled 3-D projection trajectory
    Jing Liu
    Department of Electrical and Computer Engineering, University of Wisconsin Madison, E3 311 Clinical Sciences Center, WI 53792 3252, USA
    IEEE Trans Med Imaging 25:148-57. 2006
    ..Results from volunteer and patient studies demonstrate the advantages of dynamic imaging with high spatial resolution...
  40. ncbi request reprint Principal diffusion direction in peritumoral fiber tracts: Color map patterns and directional statistics
    Aaron S Field
    Department of Radiology, University of Wisconsin, 600 Highland Avenue, CSC E3 311, Madison, WI 53792, USA
    Ann N Y Acad Sci 1064:193-201. 2005
    ..These examples serve to demonstrate our approach to the quantitation of regional diffusion tensor distributions using directional statistical methods...
  41. ncbi request reprint Motion correction and the use of motion covariates in multiple-subject fMRI analysis
    Tom Johnstone
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Hum Brain Mapp 27:779-88. 2006
    ..Based on these results, we present a general strategy for block designs, event-related designs, and hybrid designs to identify and eliminate probable motion artifacts while maximizing sensitivity to true activations...
  42. ncbi request reprint Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults
    Heather L Urry
    Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 26:4415-25. 2006
    ..Individual differences yielded the predicted link between brain function while reducing negative affect in the laboratory and diurnal regulation of endocrine activity in the home environment...
  43. pmc Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imaging
    Barbara B Bendlin
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
    Neuroimage 42:503-14. 2008
    ....
  44. ncbi request reprint Human amygdala responses during presentation of happy and neutral faces: correlations with state anxiety
    Leah H Somerville
    W M Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin, Madison, Wisconsin 53705, USA
    Biol Psychiatry 55:897-903. 2004
    ..This study assessed amygdala response to happy and neutral facial expressions in an experimental paradigm devoid of primary negatively valenced comparison expressions...
  45. pmc Helium-3 MR q-space imaging with radial acquisition and iterative highly constrained back-projection
    Rafael L O'Halloran
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53792, USA
    Magn Reson Med 63:41-50. 2010
    ..This technique represents the first demonstration of a spatially resolved hyperpolarized helium-3 q-space imaging technique and shows promise for microstructural evaluation of lung disease in three dimensions...
  46. ncbi request reprint Myelin water fraction in human cervical spinal cord in vivo
    Yijing Wu
    Department of Medical Physics, University of Wisconsin Medical School, Madison, WI 53792 3252, USA
    J Comput Assist Tomogr 30:304-6. 2006
    ..This technical note reports the test-retest reproducibility of a short T2-based estimate of myelin content in human spinal cord in vivo...
  47. pmc A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys
    Erik K Kastman
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
    J Neurosci 30:7940-7. 2010
    ..Our observations suggest that the CR-induced benefit of reduced iron deposition and preserved motor function may indicate neural protection similar to effects described previously in aging rodent and primate species...
  48. ncbi request reprint Diffusion tensor imaging of the corticospinal tract before and after mass resection as correlated with clinical motor findings: preliminary data
    Bryan J Laundre
    Department of Radiology, University of Wisconsin Medical School, Madison, WI 53792 3252, USA
    AJNR Am J Neuroradiol 26:791-6. 2005
    ..To that end, we sought correlations between preoperative and postoperative DTI and clinical motor deficits in patients with space-occupying lesions involving the corticospinal tract (CST)...
  49. doi request reprint Reduced evoked gamma oscillations in the frontal cortex in schizophrenia patients: a TMS/EEG study
    Fabio Ferrarelli
    Department of Psychiatry, University of Wisconsin, Madison, WI, USA
    Am J Psychiatry 165:996-1005. 2008
    ..The authors investigated EEG responses in schizophrenia patients and healthy comparison subjects following the application of TMS to the premotor cortex...
  50. ncbi request reprint Diffusion tensor imaging in an infant with traumatic brain swelling
    Aaron S Field
    Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792 3252, USA
    AJNR Am J Neuroradiol 24:1461-4. 2003
    ..This case engenders important hypotheses regarding mechanisms of traumatic brain swelling and anisotropic diffusion of water in pathologic tissues...
  51. ncbi request reprint Inverse amygdala and medial prefrontal cortex responses to surprised faces
    Hackjin Kim
    W M Keck Laboratory for Functional Brain Imaging, Department of Psychiatry, University of Wisconsin Madison, 53705, USA
    Neuroreport 14:2317-22. 2003
    ....
  52. ncbi request reprint Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm
    Brian P Witwer
    Department ofNeurological Surgery, University of Wisconsin School of Medicine, Madison 53792, USA
    J Neurosurg 97:568-75. 2002
    ..The aim of this study was to demonstrate the role of DT imaging in preoperative mapping of white matter tracts in relation to cerebral neoplasms...
  53. ncbi request reprint White matter tractography using diffusion tensor deflection
    Mariana Lazar
    Department of Physics, University of Utah, Salt Lake City, Utah, USA
    Hum Brain Mapp 18:306-21. 2003
    ..This approach is promising for mapping the organizational patterns of white matter in the human brain as well as mapping the relationship between major fiber trajectories and the location and extent of brain lesions...
  54. ncbi request reprint Application of Brodmann's area templates for ROI selection in white matter tractography studies
    Paul Thottakara
    Waisman Laboratory for Brain Imaging and Behavior, The Waisman Center, 1500 Highland Avenue Madison, WI 53705, USA
    Neuroimage 29:868-78. 2006
    ..In the future, this method could be used to help elucidate relationships between function and anatomical structure...
  55. ncbi request reprint Does fractional anisotropy have better noise immunity characteristics than relative anisotropy in diffusion tensor MRI? An analytical approach
    Khader M Hasan
    Department of Radiology, University of Texas Medical School at Houston, Houston, Texas, USA
    Magn Reson Med 51:413-7. 2004
    ..This theoretical behavior was verified using both Monte Carlo simulations and bootstrap analysis of DT-MRI data acquired in a spherical water phantom and normal human subjects...
  56. ncbi request reprint Correction of slab boundary artifact using histogram matching
    Eugene G Kholmovski
    Department of Physics, University of Utah, Salt Lake City, Utah 84108, USA
    J Magn Reson Imaging 15:610-7. 2002
    ..To improve the imaging efficiency of multi-slab three-dimensional acquisitions by decreasing slab overlap and the number of blanked slices...
  57. pmc A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder
    Paul J Whalen
    Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
    Biol Psychiatry 63:858-63. 2008
    ..Here, we sought to determine whether pretreatment amygdala and rostral ACC (rACC) reactivity to facial expressions could predict treatment outcomes in patients with generalized anxiety disorder (GAD)...
  58. ncbi request reprint UNFOLD using a temporal subtraction and spectral energy comparison technique
    Yijing Wu
    Department of Physics, University of Utah, Salt Lake City, Utah, USA
    Magn Reson Med 48:559-64. 2002
    ..The combination resulted in a factor of 4 improvement in acquisition speed. Application of this method to a time-resolved, contrast-enhanced flow phantom study is presented...

Research Grants9

  1. DIFFUSION MRI OF THE HUMAN BRAIN
    Andrew Alexander; Fiscal Year: 2003
    ..A new model of tissue diffusion with two tensor components will be evaluated. This project is a comprehensive approach to improving the accuracy and understanding of white matter mapping techniques within in the human brain. ..
  2. Structural & Functional Measures of Brain Development
    Andrew Alexander; Fiscal Year: 2004
    ..Future studies of brain development in children with developmental disabilities (e.g., Autism, Fragile X, Downs, etc.) will be designed and performed based upon the results from this study. ..
  3. DIFFUSION MRI OF THE HUMAN BRAIN
    Andrew Alexander; Fiscal Year: 2007
    ..Pilot studies will be performed to evaluate if these innovative diffusion imaging methods are promising for clinical applications. ..