Anthony J Aldave


Affiliation: University of California
Country: USA


  1. Aldave A, Principe A, Lin D, Yellore V, Small K. Lattice dystrophy-like localized amyloidosis of the cornea secondary to trichiasis. Cornea. 2005;24:112-5 pubmed
  2. Aldave A, Shih J, Jovkar S, McLeod S. Peripheral keratitis associated with erythema elevatum diutinum. Am J Ophthalmol. 2003;135:389-90 pubmed
    ..Erythema elevatum diutinum should be included in the differential diagnosis of vasculitic peripheral keratitis. ..
  3. Lenis T, Chiu S, Law S, Yu F, Aldave A. Safety of Concurrent Boston Type I Keratoprosthesis and Glaucoma Drainage Device Implantation. Ophthalmology. 2017;124:12-19 pubmed publisher
    ..None of the 46 GDDs placed at the same time as the KPro became exposed during an average follow-up of 44 months. Compared with KPro alone, GDD placement combined with KPro was not associated with increased postoperative complications. ..
  4. St Clair R, Sharma A, Huang D, Yu F, Goldich Y, Rootman D, et al. Development of a nomogram for femtosecond laser astigmatic keratotomy for astigmatism after keratoplasty. J Cataract Refract Surg. 2016;42:556-62 pubmed publisher
    ..The nomogram generated should improve the accuracy of post-keratoplasty femtosecond laser AK. None of the authors has a financial or proprietary interest in any material or method mentioned. ..
  5. Aldave A, Dematteo J, Glasser D, Tu E, Iliakis B, Nordlund M, et al. Report of the Eye Bank Association of America medical advisory board subcommittee on fungal infection after corneal transplantation. Cornea. 2013;32:149-54 pubmed publisher
    ..Although a nonsignificant increasing trend in the rate of fungal infection has been observed over the past 6 years, it is not sufficiently compelling to pursue antifungal supplementation of donor storage media. ..
  6. Aldave A, Kamal K, Vo R, Yu F. The Boston type I keratoprosthesis: improving outcomes and expanding indications. Ophthalmology. 2009;116:640-51 pubmed publisher
  7. Aldave A, Yellore V, Bourla N, Momi R, Khan M, Salem A, et al. Autosomal recessive CHED associated with novel compound heterozygous mutations in SLC4A11. Cornea. 2007;26:896-900 pubmed
  8. Aldave A, Rayner S, Salem A, Yoo G, Kim B, Saeedian M, et al. No pathogenic mutations identified in the COL8A1 and COL8A2 genes in familial Fuchs corneal dystrophy. Invest Ophthalmol Vis Sci. 2006;47:3787-90 pubmed
  9. Aldave A, Rayner S, King J, Affeldt J, Yellore V. A unique corneal dystrophy of Bowman's layer and stroma associated with the Gly623Asp mutation in the transforming growth factor beta-induced (TGFBI) gene. Ophthalmology. 2005;112:1017-22 pubmed

More Information


  1. Aldave A, Yellore V, Salem A, Yoo G, Rayner S, Yang H, et al. No VSX1 gene mutations associated with keratoconus. Invest Ophthalmol Vis Sci. 2006;47:2820-2 pubmed
    ..The absence of pathogenic mutations in the VSX1 gene in a large number of unrelated KTCN patients indicates that other genetic factors are involved in the development of this disorder. ..
  2. Aldave A, Bourla N, Yellore V, Rayner S, Khan M, Salem A, et al. Keratoconus is not associated with mutations in COL8A1 and COL8A2. Cornea. 2007;26:963-5 pubmed
    ..The absence of pathogenic mutations in COL8A1 and COL8A2 in patients with keratoconus indicates that other genetic factors are involved in the pathogenesis of this corneal ectatic disorder. ..
  3. Aldave A, Rayner S, Principe A, Affeldt J, Katsev D, Yellore V. Analysis of fifteen positional candidate genes for Schnyder crystalline corneal dystrophy. Mol Vis. 2005;11:713-6 pubmed
    ..To identify the genetic basis of Schnyder crystalline corneal dystrophy (SCCD) through screening of positional candidate genes in affected patients...
  4. Aldave A, Rayner S, Kim B, Prechanond A, Yellore V. Unilateral lattice corneal dystrophy associated with the novel His572del mutation in the TGFBI gene. Mol Vis. 2006;12:142-6 pubmed
    ..To report a novel mutation in the TGFBI gene, c.1761_1763del (p.His572del), associated with a unilateral variant of lattice corneal dystrophy (LCD)...
  5. Aldave A, Sonmez B, Bourla N, Schultz G, Papp J, Salem A, et al. Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2. Ophthalmic Genet. 2007;28:57-67 pubmed
    ..In addition, no pathogenic sequence variations were found in DCN, DSPG3, LUM, PITX2 and FOXC1, which have also been implicated in corneal and anterior segment dysgenesis. ..
  6. Aldave A, Yellore V, Yu F, Bourla N, Sonmez B, Salem A, et al. Posterior polymorphous corneal dystrophy is associated with TCF8 gene mutations and abdominal hernia. Am J Med Genet A. 2007;143A:2549-56 pubmed
    ..In these families, the presence of apparently causative TCF8 mutations is associated with abdominal and inguinal hernias...
  7. Aldave A, Yellore V, Principe A, Abedi G, Merrill K, Chalukya M, et al. Candidate gene screening for posterior polymorphous dystrophy. Cornea. 2005;24:151-5 pubmed
    ..The initial 3 genes chosen, ID1, BCL2L1, and VSX1, lie within the region on chromosome 20 to which the PPCD gene has been linked, and mutations in VSX1 have previously been identified in patients with PPCD...
  8. Aldave A, Yellore V, Vo R, Kamal K, Rayner S, Plaisier C, et al. Exclusion of positional candidate gene coding region mutations in the common posterior polymorphous corneal dystrophy 1 candidate gene interval. Cornea. 2009;28:801-7 pubmed publisher
    ..Instead, the causal variant is most likely a coding region deletion or a variant in a noncoding region of the PPCD1 common support interval. ..
  9. Aldave A, Rosenwasser G, Yellore V, Papp J, Sobel E, Pham M, et al. Linkage of posterior amorphous corneal dystrophy to chromosome 12q21.33 and exclusion of coding region mutations in KERA, LUM, DCN, and EPYC. Invest Ophthalmol Vis Sci. 2010;51:4006-12 pubmed publisher
    ..Linkage and haplotype analyses identified 12q21.33 as a locus for PACD. However, no mutations were identified in the candidate genes (KERA, LUM, DCN, EPYC) within this region. ..
  10. Aldave A, Gutmark J, Yellore V, Affeldt J, Meallet M, Udar N, et al. Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene. Am J Ophthalmol. 2004;138:772-81 pubmed
    ..To report a phenotypic variant of lattice corneal dystrophy associated with two missense changes, Ala546Asp and Pro551Gln, in the transforming growth factor-beta-induced gene (TGFBI)...
  11. Aldave A, Yellore V, Thonar E, Udar N, Warren J, Yoon M, et al. Novel mutations in the carbohydrate sulfotransferase gene (CHST6) in American patients with macular corneal dystrophy. Am J Ophthalmol. 2004;137:465-73 pubmed
    ..To further characterize the mutations within the CHST6 gene responsible for causing macular corneal dystrophy in a cohort of affected patients from the United States...
  12. Aldave A, Mabon M, Hollander D, McLeod S, Spencer W, Abbott R. Spontaneous corneal hydrops and perforation in keratoconus and pellucid marginal degeneration. Cornea. 2003;22:169-74 pubmed
    ..To report two cases of pellucid marginal degeneration and one case of keratoconus associated with spontaneous corneal hydrops leading either to perforation or imminent perforation, requiring urgent keratoplasty...