Research Topics
| Daniel AlbertSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
The practice of ophthalmology in rural Wisconsin in the mid-19th century: from the casebooks of Francis Paddock, MDDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Arch Ophthalmol 128:783-8. 2010..His life as a frontier physician and leading citizen of his community are documented in the context of 19th-century medicine in America and Wisconsin...
Effectiveness of 1alpha-hydroxyvitamin D2 in inhibiting tumor growth in a murine transgenic pigmented ocular tumor modelDaniel M Albert
Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
Arch Ophthalmol 122:1365-9. 2004..These animals develop pigmented intraocular tumors primarily from the retinal pigment epithelium that closely resemble the histologic features and growth pattern of human choroidal melanoma...- A study of iridectomy histopathologic features of latanoprost- and non-latanoprost-treated patientsDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
Arch Ophthalmol 122:1680-5. 2004.... - Effectiveness of vitamin D analogues in treating large tumors and during prolonged use in murine retinoblastoma modelsDaniel M Albert
Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
Arch Ophthalmol 122:1357-62. 2004.... - Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor Vitamin D analogDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
J Steroid Biochem Mol Biol 97:165-72. 2005..To investigate the effectiveness of 2-methylene-19-nor-(20S)-1alpha-hydroxybishomopregnacalciferol (2MbisP) in inhibiting the growth of retinoblastoma (RB) and neuroblastoma (NB)... - Postoperative visual acuity in patients with fuchs dystrophy undergoing descemet membrane-stripping automated endothelial keratoplasty: correlation with the severity of histologic changesDorrie M Happ
Duluth Family Medicine Residency Program, Duluth, Minnesota, USA
Arch Ophthalmol 130:33-8. 2012.... 
A study of histopathological features of latanoprost-treated irides with or without darkening compared with non-latanoprost-treated iridesDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, K6 412 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 4673, USA
Arch Ophthalmol 126:626-31. 2008..To study the histopathological features of latanoprost-treated irides with or without darkening, compared with non-latanoprost-treated irides...- Toxicity and dose-response studies of 1-alpha hydroxyvitamin D2 in LH-beta-tag transgenic miceDaniel G Dawson
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine, Madison, Wisconsin, USA
Ophthalmology 110:835-9. 2003..1alpha-OH-D(2) has approval by the Food and Drug Administration as an investigative drug for cancer treatment, and has shown efficacy with low toxicity in adult cancer trials. 1alpha-OH-D(2) meets the criteria for human clinical trials... - 1 alpha-Hydroxyvitamin D2 inhibits growth of human neuroblastomaPaul R Van Ginkel
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, K6 412 CSC, Madison, WI 53792, USA
J Neurooncol 85:255-62. 2007..There should not be major obstacles to starting Phase I and II clinical trials with this drug in pediatric patients with high-risk neuroblastoma... - Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survivalPaul R Van Ginkel
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
Cancer Res 64:128-34. 2004..These data show that the Axl pathway mediates increased survival of uveal melanoma cells, potentially advantageous during cancer dormancy, and that Axl may function in part through regulation of Cyr61... - Toxicity and dose-response studies of 1 alpha-hydroxyvitamin D2 in LH beta-Tag transgenic miceDaniel G Dawson
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
Trans Am Ophthalmol Soc 100:125-9. 2002..1 alpha-OH-D2 meets the criteria for human clinical trials... - Radial optic neurotomy using nasal and temporal approach incisions: histopathologic study in human cadaver eyesMichael M Altaweel
Department of Ophthalmology and Visual Sciences, University of Wisconsin, 2870 University Ave, Ste 206, Madison, WI 53705, USA
Arch Ophthalmol 125:1553-7. 2007..To examine the structural effect of radial optic neurotomy (RON) using nasal and temporal approach incisions on the nasal side of the optic nerve (ON) using dominant and nondominant hands in human cadaver eyes... - Eyelid fibrous hamartoma with conjunctival angioma in an infantYasmin S Bradfield
University of Wisconsin, Department of Ophthalmology and Visual Sciences, 2870 University Ave, Suite 206, Madison, WI 53705, USA
Arch Ophthalmol 125:843-5. 2007 - Ocular tuberculosisMatthew J Thompson
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
Arch Ophthalmol 123:844-9. 2005 - Vitamin D analogues increase p53, p21, and apoptosis in a xenograft model of human retinoblastomaIsabelle Audo
Department of Ophthalmology, University of Wisconsin Madison Medical School, Madison, WI 53706, USA
Invest Ophthalmol Vis Sci 44:4192-9. 2003..To study the antineoplastic effect of vitamin D analogues in a xenograft model of human retinoblastoma... - Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth LectureDaniel M Albert
Department of Ophthalmology and Visual Sciences, School of Medicine, Madison, WI 53792 3284, USA
Ophthalmic Genet 23:137-56. 2002..We identified vitamin D receptors in retinoblastoma and examined the effectiveness and mechanism of action of these analogs... - Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunctionPaul R Van Ginkel
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Invest Ophthalmol Vis Sci 49:1299-306. 2008..To test the efficacy of resveratrol, a nontoxic plant product, in the treatment of uveal melanoma... - Calcitriol is a potent inhibitor of retinal neovascularizationDaniel M Albert
Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53792 4673, USA
Invest Ophthalmol Vis Sci 48:2327-34. 2007..The purpose of this study was to evaluate the antiangiogenic activity of calcitriol (1,25-dihydroxyvitamin D(3)) in vivo and its effect on retinal endothelial cell (EC) proliferation, migration, and capillary morphogenesis in vitro... - Expression of angiogenic factors Cyr61 and tissue factor in uveal melanomaTeresa M Walker
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Room K6/466 Clinical Sciences Center, Madison, WI 53792, USA
Arch Ophthalmol 120:1719-25. 2002..CLINICAL RELEVANCE: New immunotherapies have been devised for the treatment of cancer based on the expression of TF. Similar approaches may be effective in treating uveal melanoma... - Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondriaPaul R Van Ginkel
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Clin Cancer Res 13:5162-9. 2007..Because resveratrol, a natural plant product, has been reported to have limited toxicity at chemotherapeutic levels, we investigated its efficacy in the treatment of neuroblastoma as well as its underlying mechanism of action... - Evaluation of the antitumor effects of Herpes simplex virus lacking ribonucleotide reductase in a murine retinoblastoma modelAmy E Cullinan
Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, WI 53706, USA
Curr Eye Res 29:167-72. 2004.... - Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancerDhruv Sareen
Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Mol Pharmacol 72:1466-75. 2007..Thus, RES may prove useful as a nontoxic alternative for breast cancer treatment... - Mitochondria as the primary target of resveratrol-induced apoptosis in human retinoblastoma cellsDhruv Sareen
Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Invest Ophthalmol Vis Sci 47:3708-16. 2006.... - Iris melanocyte numbers in Asian, African American, and Caucasian iridesDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
Trans Am Ophthalmol Soc 101:217-21; discussion 221-2. 2003..This difference appears to be due to the combination of smaller iris area and lower melanocyte density in the Asian irides. The possibility exists that this may be a factor in ethnic variations in certain ocular diseases... - Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degenerationDaniel M Albert
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, K6 458 CSC, Madison, WI 53792 4673, USA
Arch Ophthalmol 128:212-22. 2010..To study the progressive changes of intense cyclic light-induced retinal degeneration and to determine whether it results in choroidal neovascularization (CNV)... - Sympathetic ophthalmia following evisceration: a rare caseGregory J Griepentrog
Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA
Ophthal Plast Reconstr Surg 21:316-8. 2005..We provide a brief review of sympathetic ophthalmia following evisceration and discuss the importance of a high degree of clinical suspicion and prompt treatment with high-dose systemic corticosteroids or other immunomodulators... - Mechanism and clinical significance of prostaglandin-induced iris pigmentationJohan W Stjernschantz
Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 572 BMC, S-751 82 Uppsala, Sweden
Surv Ophthalmol 47:S162-75. 2002.... - Histopathologic characteristics of choroidal melanoma in eyes enucleated after iodine 125 brachytherapy in the collaborative ocular melanoma studyRobert B Avery
Division of Ophthalmology, University of New Mexico, Albuquerque, USA
Arch Ophthalmol 126:207-12. 2008..To describe the histopathologic findings in eyes with uveal melanoma that had secondary enucleation after failed brachytherapy plaque treatment... - The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: IV. Local treatment failure and enucleation in the first 5 years after brachytherapy. COMS report no. 19Lee M Jampol
Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois, USA
Ophthalmology 109:2197-206. 2002..This analysis documents the efficacy of brachytherapy to achieve sustained local tumor control and to conserve the globe... - Uveal melanoma masquerading as pigment dispersion glaucomaDavid L Johnson
Arch Ophthalmol 126:868-9. 2008 - Prostaglandin-induced hair growthMurray A Johnstone
Glaucoma Consultants Northwest, Swedish Medical Center, Seattle, WA 98104, USA
Surv Ophthalmol 47:S185-202. 2002..Correlation with laboratory studies suggests that initiation and completion of latanoprost hair growth effects occur very early in anagen and the likely target is the dermal papilla... - Toxicity and dose-response studies of 1alpha-hydroxyvitamin D2 in a retinoblastoma xenograft modelRichard J Grostern
Department of Ophthalmology, Rush University, Chicago, IL, USA
Arch Ophthalmol 120:607-12. 2002..CONCLUSION: A vitamin D analogue, 1alpha-OH-D(2), inhibits tumor growth in this xenograft model of retinoblastoma with less toxicity than calcitriol and vitamin D(2)... - Microsatellite instability and alterations of mismatch repair protein expression in choroidal melanomasMahmoud R Hussein
Department of Pathology, Faculty of Medicine, Assuit University, Assuit University Hospitals, Assuit, Egypt
Arch Ophthalmol 123:1705-11. 2005..To the best of our knowledge, this study is the first to define both the MSI and MMR protein expression features of choroidal melanomas... - Microbial keratitis identified during eye bank screen of corneoscleral tissue harvested from patients with laser in situ keratomileusis historyV Vinod Mootha
Department of Surgery/Division of Ophthalmology, Albuquerque, NM 87131, USA
Arch Ophthalmol 122:1058-60. 2004 - Viscocanalostomy in rhesus monkeysErnst R Tamm
Department of Anatomy, Molecular Anatomy, and Embryology, , Germany
Arch Ophthalmol 122:1826-38. 2004.... - Pocket of fluid in the lamellar interface after penetrating keratoplasty and laser in situ keratomileusisDaniel G Dawson
Arch Ophthalmol 121:894-6. 2003 - Effect of latanoprost on hair growth in the bald scalp of the stump-tailed macacque: a pilot studyHideo Uno
Wisconsin Regional Primate Research Centre, School of Medicine, University of Wisconsin Madison, USA
Acta Derm Venereol 82:7-12. 2002..The vehicle group showed no effect. Further evaluation of latanoprost as an agent for treatment of human androgenetic alopecia is indicated... - Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- miceWilliam H Tolleson
Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
Arch Ophthalmol 123:1088-94. 2005.... - Drug-induced cicatrising granulomatous conjunctivitisAlon Kahana
Br J Ophthalmol 91:691-2. 2007 - Long-term survival in a patient with uveal melanoma and liver metastasisElia J Duh
Arch Ophthalmol 122:285-7. 2004 - Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994Niyati Parekh
The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA
Arch Ophthalmol 125:661-9. 2007..To evaluate the associations between levels of vitamin D (25-hydroxyvitamin D) in serum and prevalent age-related macular degeneration (AMD)... - Slitlamp, specular, and light microscopic findings of human donor corneas after laser-assisted in situ keratomileusisV Vinod Mootha
Division of Ophthalmology, Department of Surgery, The University of New Mexico Health Sciences Center and School of Medicine, 2211 LomasBoulevard NE, 2 Ambulatory Care Center, Albuquerque, NM 87131, USA
Arch Ophthalmol 122:686-92. 2004..To examine slitlamp, specular, and light microscopic features of human donor corneas known to have undergone laser-assisted in situ keratomileusis (LASIK)...
Research Grants
- THE MOLECULAR BIOLOGY OF RETINOBLASTOMADaniel Albert; Fiscal Year: 2005..2d) Determine whether I a-hydroxy-D2 and 16,23 -D3 inhibit angiogenesis in a transgenic mouse model. These studies will complete the pre-clinical investigation of the efficacy of vitamin D analogs for human treatment. ..
- MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UVEAL MELANOMADaniel Albert; Fiscal Year: 2000..5. We will characterize pigmented tumors developing in the eyes of mice expressing SV40-T antigen (SV40-Tag) under the control of the mouse tyrosinase gene, and establish the relevance of these mice as a model for human uveal melanoma. ..
- MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UYEAL MELANOMADaniel Albert; Fiscal Year: 1993..In addition we have described the inhibition of retinoblastoma growth by vitamin D compounds and sodium butyrate and we will continue to study potential therapeutic strategies in the transgenic mouse model of retinoblastoma...
- Molecular Biology of RetinoblastomaDaniel Albert; Fiscal Year: 2006..Lastly the potency of the 19-nor compounds wil be compared to standard chemotherapy and their possible synergistic effect in multi-drug treatment established. ..