Daniel Albert

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. doi request reprint The practice of ophthalmology in rural Wisconsin in the mid-19th century: from the casebooks of Francis Paddock, MD
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Arch Ophthalmol 128:783-8. 2010
  2. ncbi request reprint Effectiveness of 1alpha-hydroxyvitamin D2 in inhibiting tumor growth in a murine transgenic pigmented ocular tumor model
    Daniel M Albert
    Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    Arch Ophthalmol 122:1365-9. 2004
  3. ncbi request reprint A study of iridectomy histopathologic features of latanoprost- and non-latanoprost-treated patients
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
    Arch Ophthalmol 122:1680-5. 2004
  4. ncbi request reprint Effectiveness of vitamin D analogues in treating large tumors and during prolonged use in murine retinoblastoma models
    Daniel M Albert
    Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    Arch Ophthalmol 122:1357-62. 2004
  5. ncbi request reprint Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor Vitamin D analog
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    J Steroid Biochem Mol Biol 97:165-72. 2005
  6. pmc Postoperative visual acuity in patients with fuchs dystrophy undergoing descemet membrane-stripping automated endothelial keratoplasty: correlation with the severity of histologic changes
    Dorrie M Happ
    Duluth Family Medicine Residency Program, Duluth, Minnesota, USA
    Arch Ophthalmol 130:33-8. 2012
  7. pmc A study of histopathological features of latanoprost-treated irides with or without darkening compared with non-latanoprost-treated irides
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, K6 412 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 4673, USA
    Arch Ophthalmol 126:626-31. 2008
  8. ncbi request reprint Toxicity and dose-response studies of 1-alpha hydroxyvitamin D2 in LH-beta-tag transgenic mice
    Daniel G Dawson
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine, Madison, Wisconsin, USA
    Ophthalmology 110:835-9. 2003
  9. ncbi request reprint 1 alpha-Hydroxyvitamin D2 inhibits growth of human neuroblastoma
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, K6 412 CSC, Madison, WI 53792, USA
    J Neurooncol 85:255-62. 2007
  10. ncbi request reprint Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survival
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
    Cancer Res 64:128-34. 2004

Research Grants

  1. THE MOLECULAR BIOLOGY OF RETINOBLASTOMA
    Daniel Albert; Fiscal Year: 2005
  2. MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UVEAL MELANOMA
    Daniel Albert; Fiscal Year: 2000
  3. MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UYEAL MELANOMA
    Daniel Albert; Fiscal Year: 1993
  4. Molecular Biology of Retinoblastoma
    Daniel Albert; Fiscal Year: 2006

Collaborators

Detail Information

Publications42

  1. doi request reprint The practice of ophthalmology in rural Wisconsin in the mid-19th century: from the casebooks of Francis Paddock, MD
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Arch Ophthalmol 128:783-8. 2010
    ..His life as a frontier physician and leading citizen of his community are documented in the context of 19th-century medicine in America and Wisconsin...
  2. ncbi request reprint Effectiveness of 1alpha-hydroxyvitamin D2 in inhibiting tumor growth in a murine transgenic pigmented ocular tumor model
    Daniel M Albert
    Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    Arch Ophthalmol 122:1365-9. 2004
    ..These animals develop pigmented intraocular tumors primarily from the retinal pigment epithelium that closely resemble the histologic features and growth pattern of human choroidal melanoma...
  3. ncbi request reprint A study of iridectomy histopathologic features of latanoprost- and non-latanoprost-treated patients
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
    Arch Ophthalmol 122:1680-5. 2004
    ....
  4. ncbi request reprint Effectiveness of vitamin D analogues in treating large tumors and during prolonged use in murine retinoblastoma models
    Daniel M Albert
    Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    Arch Ophthalmol 122:1357-62. 2004
    ....
  5. ncbi request reprint Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor Vitamin D analog
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, F4 344 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3284, USA
    J Steroid Biochem Mol Biol 97:165-72. 2005
    ..To investigate the effectiveness of 2-methylene-19-nor-(20S)-1alpha-hydroxybishomopregnacalciferol (2MbisP) in inhibiting the growth of retinoblastoma (RB) and neuroblastoma (NB)...
  6. pmc Postoperative visual acuity in patients with fuchs dystrophy undergoing descemet membrane-stripping automated endothelial keratoplasty: correlation with the severity of histologic changes
    Dorrie M Happ
    Duluth Family Medicine Residency Program, Duluth, Minnesota, USA
    Arch Ophthalmol 130:33-8. 2012
    ....
  7. pmc A study of histopathological features of latanoprost-treated irides with or without darkening compared with non-latanoprost-treated irides
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, K6 412 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 4673, USA
    Arch Ophthalmol 126:626-31. 2008
    ..To study the histopathological features of latanoprost-treated irides with or without darkening, compared with non-latanoprost-treated irides...
  8. ncbi request reprint Toxicity and dose-response studies of 1-alpha hydroxyvitamin D2 in LH-beta-tag transgenic mice
    Daniel G Dawson
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine, Madison, Wisconsin, USA
    Ophthalmology 110:835-9. 2003
    ..To determine the effectiveness of a vitamin D analog, 1alpha-hydroxyvitamin D(2) (1alpha-OH-D(2)), in inhibiting retinoblastoma in a transgenic retinoblastoma model (LHbeta-Tag mouse) and to evaluate its toxicity...
  9. ncbi request reprint 1 alpha-Hydroxyvitamin D2 inhibits growth of human neuroblastoma
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, K6 412 CSC, Madison, WI 53792, USA
    J Neurooncol 85:255-62. 2007
    ..There should not be major obstacles to starting Phase I and II clinical trials with this drug in pediatric patients with high-risk neuroblastoma...
  10. ncbi request reprint Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survival
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
    Cancer Res 64:128-34. 2004
    ..These data show that the Axl pathway mediates increased survival of uveal melanoma cells, potentially advantageous during cancer dormancy, and that Axl may function in part through regulation of Cyr61...
  11. pmc Toxicity and dose-response studies of 1 alpha-hydroxyvitamin D2 in LH beta-Tag transgenic mice
    Daniel G Dawson
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
    Trans Am Ophthalmol Soc 100:125-9. 2002
    ..Previous studies of 1 alpha-OH-D2 in athymic mice with human retinoblastoma xenografts suggested efficacy in tumor suppression and suitability for human treatment...
  12. ncbi request reprint Radial optic neurotomy using nasal and temporal approach incisions: histopathologic study in human cadaver eyes
    Michael M Altaweel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 2870 University Ave, Ste 206, Madison, WI 53705, USA
    Arch Ophthalmol 125:1553-7. 2007
    ..To examine the structural effect of radial optic neurotomy (RON) using nasal and temporal approach incisions on the nasal side of the optic nerve (ON) using dominant and nondominant hands in human cadaver eyes...
  13. ncbi request reprint Eyelid fibrous hamartoma with conjunctival angioma in an infant
    Yasmin S Bradfield
    University of Wisconsin, Department of Ophthalmology and Visual Sciences, 2870 University Ave, Suite 206, Madison, WI 53705, USA
    Arch Ophthalmol 125:843-5. 2007
  14. ncbi request reprint Ocular tuberculosis
    Matthew J Thompson
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, USA
    Arch Ophthalmol 123:844-9. 2005
  15. ncbi request reprint Vitamin D analogues increase p53, p21, and apoptosis in a xenograft model of human retinoblastoma
    Isabelle Audo
    Department of Ophthalmology, University of Wisconsin Madison Medical School, Madison, WI 53706, USA
    Invest Ophthalmol Vis Sci 44:4192-9. 2003
    ..To study the antineoplastic effect of vitamin D analogues in a xenograft model of human retinoblastoma...
  16. ncbi request reprint Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth Lecture
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, School of Medicine, Madison, WI 53792 3284, USA
    Ophthalmic Genet 23:137-56. 2002
    ..We identified vitamin D receptors in retinoblastoma and examined the effectiveness and mechanism of action of these analogs...
  17. pmc Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Invest Ophthalmol Vis Sci 49:1299-306. 2008
    ..To test the efficacy of resveratrol, a nontoxic plant product, in the treatment of uveal melanoma...
  18. ncbi request reprint Calcitriol is a potent inhibitor of retinal neovascularization
    Daniel M Albert
    Departments of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, Wisconsin 53792 4673, USA
    Invest Ophthalmol Vis Sci 48:2327-34. 2007
    ..The purpose of this study was to evaluate the antiangiogenic activity of calcitriol (1,25-dihydroxyvitamin D(3)) in vivo and its effect on retinal endothelial cell (EC) proliferation, migration, and capillary morphogenesis in vitro...
  19. ncbi request reprint Expression of angiogenic factors Cyr61 and tissue factor in uveal melanoma
    Teresa M Walker
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Room K6 466 Clinical Sciences Center, Madison, WI 53792, USA
    Arch Ophthalmol 120:1719-25. 2002
    ..To study the expression of angiogenic factors Cyr61 and tissue factor (TF) in uveal melanoma and its correlation with blood vessel density...
  20. ncbi request reprint Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria
    Paul R Van Ginkel
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Clin Cancer Res 13:5162-9. 2007
    ..Because resveratrol, a natural plant product, has been reported to have limited toxicity at chemotherapeutic levels, we investigated its efficacy in the treatment of neuroblastoma as well as its underlying mechanism of action...
  21. ncbi request reprint Evaluation of the antitumor effects of Herpes simplex virus lacking ribonucleotide reductase in a murine retinoblastoma model
    Amy E Cullinan
    Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, WI 53706, USA
    Curr Eye Res 29:167-72. 2004
    ..To determine if an attenuated herpes simplex virus (HSV) lacking the large subunit of ribonucleotide reductase has antitumor effects in a transgenic mouse model of retinoblastoma (LHbetaTAg)...
  22. ncbi request reprint Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer
    Dhruv Sareen
    Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Mol Pharmacol 72:1466-75. 2007
    ..Thus, RES may prove useful as a nontoxic alternative for breast cancer treatment...
  23. ncbi request reprint Mitochondria as the primary target of resveratrol-induced apoptosis in human retinoblastoma cells
    Dhruv Sareen
    Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Invest Ophthalmol Vis Sci 47:3708-16. 2006
    ..To determine the molecular mechanisms by which resveratrol induces retinoblastoma tumor cell death...
  24. pmc Iris melanocyte numbers in Asian, African American, and Caucasian irides
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Trans Am Ophthalmol Soc 101:217-21; discussion 221-2. 2003
    ..The present investigation was carried out to compare melanocyte numbers in the irides of Asian, African American, and Caucasian brown-eyed individuals...
  25. pmc Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration
    Daniel M Albert
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, K6 458 CSC, Madison, WI 53792 4673, USA
    Arch Ophthalmol 128:212-22. 2010
    ..To study the progressive changes of intense cyclic light-induced retinal degeneration and to determine whether it results in choroidal neovascularization (CNV)...
  26. ncbi request reprint Sympathetic ophthalmia following evisceration: a rare case
    Gregory J Griepentrog
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Ophthal Plast Reconstr Surg 21:316-8. 2005
    ..We provide a brief review of sympathetic ophthalmia following evisceration and discuss the importance of a high degree of clinical suspicion and prompt treatment with high-dose systemic corticosteroids or other immunomodulators...
  27. ncbi request reprint Mechanism and clinical significance of prostaglandin-induced iris pigmentation
    Johan W Stjernschantz
    Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 572 BMC, S 751 82 Uppsala, Sweden
    Surv Ophthalmol 47:S162-75. 2002
    ....
  28. doi request reprint Histopathologic characteristics of choroidal melanoma in eyes enucleated after iodine 125 brachytherapy in the collaborative ocular melanoma study
    Robert B Avery
    Division of Ophthalmology, University of New Mexico, Albuquerque, USA
    Arch Ophthalmol 126:207-12. 2008
    ..To describe the histopathologic findings in eyes with uveal melanoma that had secondary enucleation after failed brachytherapy plaque treatment...
  29. ncbi request reprint The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: IV. Local treatment failure and enucleation in the first 5 years after brachytherapy. COMS report no. 19
    Lee M Jampol
    Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois, USA
    Ophthalmology 109:2197-206. 2002
    ..To describe the frequency and predictors of local treatment failure and enucleation after iodine 125 (I(125)) brachytherapy in patients with choroidal melanoma treated and followed up in a large randomized clinical trial...
  30. pmc Uveal melanoma masquerading as pigment dispersion glaucoma
    David L Johnson
    Arch Ophthalmol 126:868-9. 2008
  31. ncbi request reprint Prostaglandin-induced hair growth
    Murray A Johnstone
    Glaucoma Consultants Northwest, Swedish Medical Center, Seattle, WA 98104, USA
    Surv Ophthalmol 47:S185-202. 2002
    ..Correlation with laboratory studies suggests that initiation and completion of latanoprost hair growth effects occur very early in anagen and the likely target is the dermal papilla...
  32. ncbi request reprint Toxicity and dose-response studies of 1alpha-hydroxyvitamin D2 in a retinoblastoma xenograft model
    Richard J Grostern
    Department of Ophthalmology, Rush University, Chicago, IL, USA
    Arch Ophthalmol 120:607-12. 2002
    ..Although calcitriol (1,25-dihydroxycholecalciferol) and vitamin D(2) inhibit retinoblastoma growth in the athymic (nude) mouse xenograft (Y-79 cell line) model of retinoblastoma, they can cause severe toxicity...
  33. ncbi request reprint Microsatellite instability and alterations of mismatch repair protein expression in choroidal melanomas
    Mahmoud R Hussein
    Department of Pathology, Faculty of Medicine, Assuit University, Assuit University Hospitals, Assuit, Egypt
    Arch Ophthalmol 123:1705-11. 2005
    ....
  34. ncbi request reprint Microbial keratitis identified during eye bank screen of corneoscleral tissue harvested from patients with laser in situ keratomileusis history
    V Vinod Mootha
    Department of Surgery Division of Ophthalmology, Albuquerque, NM 87131, USA
    Arch Ophthalmol 122:1058-60. 2004
  35. ncbi request reprint Viscocanalostomy in rhesus monkeys
    Ernst R Tamm
    Department of Anatomy, Molecular Anatomy, and Embryology, University of Erlangen Nurnberg, Germany
    Arch Ophthalmol 122:1826-38. 2004
    ..To examine structural changes and aqueous humor outflow after viscocanalostomy in live normal monkey eyes...
  36. ncbi request reprint Pocket of fluid in the lamellar interface after penetrating keratoplasty and laser in situ keratomileusis
    Daniel G Dawson
    Arch Ophthalmol 121:894-6. 2003
  37. ncbi request reprint Effect of latanoprost on hair growth in the bald scalp of the stump-tailed macacque: a pilot study
    Hideo Uno
    Wisconsin Regional Primate Research Centre, School of Medicine, University of Wisconsin Madison, USA
    Acta Derm Venereol 82:7-12. 2002
    ..The vehicle group showed no effect. Further evaluation of latanoprost as an agent for treatment of human androgenetic alopecia is indicated...
  38. ncbi request reprint Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice
    William H Tolleson
    Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
    Arch Ophthalmol 123:1088-94. 2005
    ....
  39. pmc Drug-induced cicatrising granulomatous conjunctivitis
    Alon Kahana
    Br J Ophthalmol 91:691-2. 2007
  40. ncbi request reprint Long-term survival in a patient with uveal melanoma and liver metastasis
    Elia J Duh
    Arch Ophthalmol 122:285-7. 2004
  41. ncbi request reprint Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994
    Niyati Parekh
    The Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA
    Arch Ophthalmol 125:661-9. 2007
    ..To evaluate the associations between levels of vitamin D (25-hydroxyvitamin D) in serum and prevalent age-related macular degeneration (AMD)...
  42. ncbi request reprint Slitlamp, specular, and light microscopic findings of human donor corneas after laser-assisted in situ keratomileusis
    V Vinod Mootha
    Division of Ophthalmology, Department of Surgery, The University of New Mexico Health Sciences Center and School of Medicine, 2211 LomasBoulevard NE, 2 Ambulatory Care Center, Albuquerque, NM 87131, USA
    Arch Ophthalmol 122:686-92. 2004
    ..To examine slitlamp, specular, and light microscopic features of human donor corneas known to have undergone laser-assisted in situ keratomileusis (LASIK)...

Research Grants18

  1. THE MOLECULAR BIOLOGY OF RETINOBLASTOMA
    Daniel Albert; Fiscal Year: 2005
    ..2d) Determine whether I a-hydroxy-D2 and 16,23 -D3 inhibit angiogenesis in a transgenic mouse model. These studies will complete the pre-clinical investigation of the efficacy of vitamin D analogs for human treatment. ..
  2. MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UVEAL MELANOMA
    Daniel Albert; Fiscal Year: 2000
    ..5. We will characterize pigmented tumors developing in the eyes of mice expressing SV40-T antigen (SV40-Tag) under the control of the mouse tyrosinase gene, and establish the relevance of these mice as a model for human uveal melanoma. ..
  3. MOLECULAR BIOLOGY OF RETINOBLASTOMA AND UYEAL MELANOMA
    Daniel Albert; Fiscal Year: 1993
    ..In addition we have described the inhibition of retinoblastoma growth by vitamin D compounds and sodium butyrate and we will continue to study potential therapeutic strategies in the transgenic mouse model of retinoblastoma...
  4. Molecular Biology of Retinoblastoma
    Daniel Albert; Fiscal Year: 2006
    ..Lastly the potency of the 19-nor compounds wil be compared to standard chemotherapy and their possible synergistic effect in multi-drug treatment established. ..