H S Akiskal

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN)
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla 92161, USA
    J Affect Disord 50:175-86. 1998
  2. ncbi request reprint Toward a refined phenomenology of mania: combining clinician-assessment and self-report in the French EPIMAN study
    H S Akiskal
    International Mood Center, University of California at San Diego, VA Psychiatry Service 116A, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Affect Disord 67:89-96. 2001
  3. ncbi request reprint Validating the soft bipolar spectrum in the French National EPIDEP Study: the prominence of BP-II 1/2
    H S Akiskal
    Department of Psychiatry and International Mood Center, University of California at San Diego, VA Hospital San Diego, CA 92161, USA
    J Affect Disord 96:207-13. 2006
  4. ncbi request reprint The evolving bipolar spectrum. Prototypes I, II, III, and IV
    H S Akiskal
    Department of Psychiatry, University of California at San Diego, La Jolla, USA
    Psychiatr Clin North Am 22:517-34, vii. 1999
  5. ncbi request reprint Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, CA, USA
    J Affect Disord 59:S5-S30. 2000
  6. ncbi request reprint Proposed multidimensional structure of mania: beyond the euphoric-dysphoric dichotomy
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, CA, USA
    J Affect Disord 73:7-18. 2003
  7. ncbi request reprint Does incomplete recovery from first lifetime major depressive episode herald a chronic course of illness?
    L L Judd
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0603, USA
    Am J Psychiatry 157:1501-4. 2000
  8. ncbi request reprint TEMPS-I: delineating the most discriminant traits of the cyclothymic, depressive, hyperthymic and irritable temperaments in a nonpatient population
    H S Akiskal
    International Mood Center, Department of Psychiatry, University of California, San Diego, USA
    J Affect Disord 51:7-19. 1998
  9. ncbi request reprint Toward a validation of a new definition of agitated depression as a bipolar mixed state (mixed depression)
    F Benazzi
    Centro Lucio Bini, outpatient private practice, Rome, Italy
    Eur Psychiatry 19:85-90. 2004
  10. ncbi request reprint Mood stabilizer augmentation in apparently "unipolar" MDD: predictors of response in the naturalistic French national EPIDEP study
    Elie G Hantouche
    Department of Psychiatry, Adult Psychiatry, Mood Center, Consultation de l Humeur, Pitie Salpetriere Hospital, 47 bd de l Hopital, 75013 Paris, France
    J Affect Disord 84:243-9. 2005

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN)
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla 92161, USA
    J Affect Disord 50:175-86. 1998
    ....
  2. ncbi request reprint Toward a refined phenomenology of mania: combining clinician-assessment and self-report in the French EPIMAN study
    H S Akiskal
    International Mood Center, University of California at San Diego, VA Psychiatry Service 116A, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Affect Disord 67:89-96. 2001
    ..The present analyses sought to examine to what extent patient reports could improve formal diagnostic criteria for mania--and be validated against the Carroll-Klein (CK) psychobiological model of bipolarity...
  3. ncbi request reprint Validating the soft bipolar spectrum in the French National EPIDEP Study: the prominence of BP-II 1/2
    H S Akiskal
    Department of Psychiatry and International Mood Center, University of California at San Diego, VA Hospital San Diego, CA 92161, USA
    J Affect Disord 96:207-13. 2006
    ..In this report we test aspects of a bipolar schema proposed earlier by Akiskal and Pinto [Akiskal, H.S., Pinto, O., 1999. The evolving bipolar spectrum: Prototypes I, II, III, IV. Psychiatr. Clin. North Am. 22: 517-534.]...
  4. ncbi request reprint The evolving bipolar spectrum. Prototypes I, II, III, and IV
    H S Akiskal
    Department of Psychiatry, University of California at San Diego, La Jolla, USA
    Psychiatr Clin North Am 22:517-34, vii. 1999
    ....
  5. ncbi request reprint Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, CA, USA
    J Affect Disord 59:S5-S30. 2000
    ....
  6. ncbi request reprint Proposed multidimensional structure of mania: beyond the euphoric-dysphoric dichotomy
    H S Akiskal
    International Mood Center, University of California at San Diego, La Jolla, CA, USA
    J Affect Disord 73:7-18. 2003
    ..The few available studies have reported at least two factors, which consist of euphoric versus dysphoric-hostile subtypes. Our objective was to replicate and further enrich this literature...
  7. ncbi request reprint Does incomplete recovery from first lifetime major depressive episode herald a chronic course of illness?
    L L Judd
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0603, USA
    Am J Psychiatry 157:1501-4. 2000
    ..This study investigated the influence of incomplete recovery from first lifetime major depressive episodes on long-term outcome...
  8. ncbi request reprint TEMPS-I: delineating the most discriminant traits of the cyclothymic, depressive, hyperthymic and irritable temperaments in a nonpatient population
    H S Akiskal
    International Mood Center, Department of Psychiatry, University of California, San Diego, USA
    J Affect Disord 51:7-19. 1998
    ..Although most personality constructs have been standardized in population studies, cyclothymic, depressive, irritable and hyperthymic temperaments putatively linked to mood disorders have been classically derived from clinical observations...
  9. ncbi request reprint Toward a validation of a new definition of agitated depression as a bipolar mixed state (mixed depression)
    F Benazzi
    Centro Lucio Bini, outpatient private practice, Rome, Italy
    Eur Psychiatry 19:85-90. 2004
    ....
  10. ncbi request reprint Mood stabilizer augmentation in apparently "unipolar" MDD: predictors of response in the naturalistic French national EPIDEP study
    Elie G Hantouche
    Department of Psychiatry, Adult Psychiatry, Mood Center, Consultation de l Humeur, Pitie Salpetriere Hospital, 47 bd de l Hopital, 75013 Paris, France
    J Affect Disord 84:243-9. 2005
    ....
  11. ncbi request reprint [Hyperthymic and depressive temperaments study in controls, as a function of their familial loading for mood disorders]
    P Chiaroni
    Clinique du Cap, 20228 Luri
    Encephale 30:509-15. 2004
    ..The cyclothymic temperament is studied as part of another report)...
  12. ncbi request reprint Cyclothymic OCD: a distinct form?
    E G Hantouche
    Mood Center, Department of Psychiatry, Pitie Salpetriere Hospital, 47 bd de l Hopital, 75013 Paris, France
    J Affect Disord 75:1-10. 2003
    ..However in practice, resistant or severe OCD patients not infrequently suffer from a masked or hidden comorbid bipolar disorder...
  13. ncbi request reprint The relationship of Kraepelian affective temperaments (as measured by TEMPS-I) to the tridimensional personality questionnaire (TPQ)
    I Maremmani
    Department of Psychiatry, Neurobiology, Pharmacology and Biotecnology, University of Pisa, Via Roma, 67, 56100, Pisa, Italy
    J Affect Disord 85:17-27. 2005
    ..There is considerable uncertainty in the current literature about the relationship between personality dimensions and affective temperaments...
  14. ncbi request reprint Toward a validation of a tripartite concept of a putative anxious temperament: psychometric data from a French national general medical practice study
    E G Hantouche
    Mood Center, Pitie Salpetriere Hospital, University of Paris, Paris, France
    J Affect Disord 85:37-43. 2005
    ..It is presently unknown whether it is a distinct or unitary construct of a melange of anxious traits related to Cluster-C personality disorders...
  15. ncbi request reprint The cyclothymic temperament in healthy controls and familially at risk individuals for mood disorder: endophenotype for genetic studies?
    Pierre Chiaroni
    Service de Psychiatrie, Hopital Sainte Marguerite, Bd Sainte Marguerite, 13009 Marseille, France
    J Affect Disord 85:135-45. 2005
    ..As bipolar disorder is a familial illness, an examination of cyclothymic temperament (CT) in controls and relatives of bipolar patients is of major relevance...
  16. ncbi request reprint Cyclothymic temperament as a prospective predictor of bipolarity and suicidality in children and adolescents with major depressive disorder
    F J Kochman
    Department of Child and Adolescent Psychiatry, Unit 59I13, 304 Avenue Motte, 59100 Roubaix, France
    J Affect Disord 85:181-9. 2005
    ....
  17. ncbi request reprint Toward a definition of a cyclothymic behavioral endophenotype: which traits tap the familial diathesis for bipolar II disorder?
    E G Hantouche
    Université Paris VI Mood Center, Hopital Pitie Salpetriere, Paris, France
    J Affect Disord 96:233-7. 2006
    ....
  18. ncbi request reprint Clinical and psychometric characterization of depression in mixed mania: a report from the French National Cohort of 1090 manic patients
    E G Hantouche
    Mood Center, Adult Psychiatry Department, Pitie Salpetriere Hospital, 47 bd de l Hopital, 75013 Paris Cedex 13, France
    J Affect Disord 96:225-32. 2006
    ..This work eventually led to the Kraepelinian synthesis of all manic, mixed, and depressive states into the unitary rubric of "manic-depressive insanity (1899/1921)...
  19. ncbi request reprint The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention
    Judit Balazs
    Vadaskert Child Psychiatric Hospital and Outpatient Clinic, Budapest, Hungary
    J Affect Disord 91:133-8. 2006
    ..Previous reports have shown a significant relationship between suicide ideation and mixed depression. The aim of this study was to explore the prevalence and clinical characteristics of mixed depression among non-violent suicide attempters...
  20. ncbi request reprint The manic-depressive mixed state: familial, temperamental and psychopathologic characteristics in 108 female inpatients
    G F Placidi
    Institute of Psychiatry, University of Pisa, Italy
    Eur Arch Psychiatry Clin Neurosci 240:234-9. 1991
    ..These characteristics tend to identify the mixed state as a distinct longitudinal pattern of manic-depressive illness...
  21. ncbi request reprint [Bipolar obsessive-compulsive disorder: confirmation of results of the "ABC-OCD" survey in 2 populations of patient members versus non-members of an association]
    E G Hantouche
    Centre de l humeur, Departement de Psychiatrie, Hopital Pitie Salpetriere, 47, Boulevard de l Hopital, 75013 Paris
    Encephale 28:21-8. 2002
    ..More in depth analyses are now undertaken in order to investigate the characteristics of "bipolar OCD" by comparison to "non bipolar OCD"...
  22. ncbi request reprint [Temperament and affective disorders. The TEMPS-A Scale as a convergence of European and US-American concepts]
    H S Akiskal
    International Mood Centre, Department of Psychiatry, University of California at San Diego, USA
    Nervenarzt 73:262-71. 2002
    ..Clinical description and scientific implications are described in the light of recent work by Akiskal and the German version of the TEMPS-A scale, a self-report questionnaire for assessing temperament...
  23. ncbi request reprint The feasibility of self-assessment of dysphoric mania in the French national EPIMAN study
    E G Hantouche
    , , , Paris, France
    J Affect Disord 67:97-103. 2001
    ..Self-assessment was capable of capturing accurately the subthreshold depressive symptomatology of mixed mania, which can be missed in hetero-evaluation by hasty clinical interview...
  24. ncbi request reprint Psychotic and nonpsychotic bipolar mixed states: comparisons with manic and schizoaffective disorders
    H S Akiskal
    Institute of Clinical Psychiatry, University of Pisa, Italy
    Eur Arch Psychiatry Clin Neurosci 243:75-81. 1993
    ..The findings overall suggest that the presence of psychosis had relatively little impact on mixed states, which appear more based on temperamental characteristics...
  25. ncbi request reprint Single episode of major depressive disorder. First episode of recurrent mood disorder or distinct subtype of late-onset depression?
    G B Cassano
    II Psychiatric Clinic, University of Pisa, Italy
    Eur Arch Psychiatry Clin Neurosci 242:373-80. 1993
    ..The implications of these findings for the now largely abandoned category of "involutional melancholia" are discussed...
  26. ncbi request reprint Is mood-incongruent manic psychosis a distinct subtype?
    C Toni
    Department of Psychiatry, University of Pisa, Via Roma 67, 56100, Pisa, Italy
    Eur Arch Psychiatry Clin Neurosci 251:12-7. 2001
    ..Despite several research reports on incongruent psychotic features in mania, whether such features define a distinct disorder is unsettled...
  27. ncbi request reprint [Frequency and clinical aspects of bipolar II disorder in a French multicenter study: EPIDEP]
    J F Allilaire
    , , 47, , 75013 Paris
    Encephale 27:149-58. 2001
    ..In total, EPIDEP data indicated that recognition of BP-II is feasible in diverse practice settings and proposed for clinicians some adapted clinical tools for assessing soft bipolarity...
  28. ncbi request reprint [Cyclothymic obsessive-compulsive disorder. Clinical characteristics of a neglected and under-recognized entity]
    E G Hantouche
    Centre de l humeur, Departement de psychiatrie adulte, Hopital Pitie Salpetriere, 47 bd de l Hopital, 75013 Paris
    Presse Med 31:644-8. 2002
    ..However some recent publications have suggested that bipolar comorbidity occurs in authentic OCD and its presence has a differential impact on the clinical picture and course of OCD...
  29. ncbi request reprint Process of adaptation to Spanish of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego Scale. Self applied version (TEMPS-A)
    J Sanchez-Moreno
    Departamento de Psiquiatria, Universidad Autonoma de Madrid, Programa de Trastornos Bipolares, Institut Clínic de Neurociències, Hospital Clinic, Barcelona, Spain
    Actas Esp Psiquiatr 33:325-30. 2005
    ..The TEMPS-A is a self-evaluation measure to assess four affective temperaments (hyperthymic, depressive, cyclothymic and irritable) and anxious temperament...
  30. ncbi request reprint Proposed endophenotypes of dysthymia: evolutionary, clinical and pharmacogenomic considerations
    A B Niculescu
    Department of Psychiatry, School of Medicine, University of California, San Diego, La Jolla, CA, USA
    Mol Psychiatry 6:363-6. 2001
    ..It would also expand the pool of subjects that may be enrolled in genetic and pharmacogenomic research studies...
  31. ncbi request reprint Bipolar II and unipolar comorbidity in 153 outpatients with social phobia
    G Perugi
    Department of Psychiatry, University of Pisa, Via Roma 67, 56100 Pisa, Italy
    Compr Psychiatry 42:375-81. 2001
    ..In a significant minority of cases, protracted social anxiety may hypothetically have represented, along with inhibited depression, the dimensional opposite of gregarious hypomania...
  32. ncbi request reprint Putative clinical subtypes of social phobia: a factor-analytical study
    G Perugi
    Department of Psychiatry, University of Pisa, Via Roma 67, 56100, Pisa, Italy
    Acta Psychiatr Scand 104:280-8. 2001
    ..CONCLUSION: The emerging multidimensional structure of phobia is congruent with, and further enriches, the existing literature...
  33. ncbi request reprint The significance of psychotic features in manic episodes: a report from the NIMH collaborative study
    W Coryell
    University of Iowa College of Medicine, Psychiatry Research, 2-205 MEB, Iowa City, IA 52242-1000, USA
    J Affect Disord 67:79-88. 2001
    ..Psychotic features are much less predictive of future psychosis when they occur within a manic syndrome than when they occur within a depressive syndrome...
  34. ncbi request reprint Paula Clayton: her role in the Development of the Field of Affectiveology
    H S Akiskal
    J Affect Disord 92:1-2. 2006