Shahab A Akhter

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Recurrent primary cardiac malignant fibrous histiocytoma following orthotopic heart transplantation
    Shahab A Akhter
    Division of Cardiac Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0558, USA
    J Heart Lung Transplant 23:1447-50. 2004
  2. doi request reprint Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death
    Prakash K Pandalai
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Thorac Cardiovasc Surg 135:792-8. 2008
  3. ncbi request reprint Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model
    Kelly M McLean
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Heart Lung Transplant 26:522-8. 2007
  4. ncbi request reprint Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death
    Kelly M McLean
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Heart Lung Transplant 26:78-84. 2007
  5. pmc Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction
    Christian F Bulcao
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Heart Lung Transplant 29:346-51. 2010
  6. ncbi request reprint Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs
    Jefferson M Lyons
    Cincinnati Children s Hospital Medical Center, Division of Cardiothoracic Surgery, Cincinnati, Ohio 45229, USA
    J Heart Lung Transplant 24:2249-54. 2005
  7. pmc Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2
    Christian F Bulcao
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Ann Thorac Surg 86:1189-94. 2008
  8. doi request reprint Inhibition of protein kinase C alpha improves myocardial beta-adrenergic receptor signaling and ventricular function in a model of myocardial preservation
    Karen M D'Souza
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Thorac Cardiovasc Surg 135:172-9, 179.e1. 2008
  9. pmc Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform
    Sudarsan Rajan
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0524, USA
    Circulation 121:410-8. 2010
  10. ncbi request reprint Restoration of myocardial beta-adrenergic receptor signaling after left ventricular assist device support
    Prakash K Pandalai
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0558, USA
    J Thorac Cardiovasc Surg 131:975-80. 2006

Research Grants

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Recurrent primary cardiac malignant fibrous histiocytoma following orthotopic heart transplantation
    Shahab A Akhter
    Division of Cardiac Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0558, USA
    J Heart Lung Transplant 23:1447-50. 2004
    ..This case represents the only reported long-term survival following cardiac transplantation for MFH and describes our management strategy for local recurrence in this patient...
  2. doi request reprint Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death
    Prakash K Pandalai
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Thorac Cardiovasc Surg 135:792-8. 2008
    ..We hypothesized that acute beta-blockade can prevent myocardial beta-adrenergic receptor desensitization after brain death through attenuation of G protein-coupled receptor kinase 2 activity, resulting in improved cardiac function...
  3. ncbi request reprint Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model
    Kelly M McLean
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Heart Lung Transplant 26:522-8. 2007
    ..We hypothesized that acute betaAR antagonism could improve myocardial function after brain death by preserving betaAR signaling...
  4. ncbi request reprint Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death
    Kelly M McLean
    Division of Cardiothoracic Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Heart Lung Transplant 26:78-84. 2007
    ....
  5. pmc Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction
    Christian F Bulcao
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Heart Lung Transplant 29:346-51. 2010
    ..We investigated the potential role of myocardial interleukin (IL)-6 signaling through the JAK2-STAT3 pathway, which can lead to the generation of nitric oxide (NO) and decreased cardiac myocyte contractility...
  6. ncbi request reprint Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs
    Jefferson M Lyons
    Cincinnati Children s Hospital Medical Center, Division of Cardiothoracic Surgery, Cincinnati, Ohio 45229, USA
    J Heart Lung Transplant 24:2249-54. 2005
    ..The hypothesis was that glucocorticoid administration alone could reduce BD-associated cardiac dysfunction...
  7. pmc Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2
    Christian F Bulcao
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Ann Thorac Surg 86:1189-94. 2008
    ....
  8. doi request reprint Inhibition of protein kinase C alpha improves myocardial beta-adrenergic receptor signaling and ventricular function in a model of myocardial preservation
    Karen M D'Souza
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Thorac Cardiovasc Surg 135:172-9, 179.e1. 2008
    ....
  9. pmc Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform
    Sudarsan Rajan
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0524, USA
    Circulation 121:410-8. 2010
    ..Although TPM1alpha (also called alpha-TM) is the predominant TM isoform in human hearts, the precise TM isoform composition remains unclear...
  10. ncbi request reprint Restoration of myocardial beta-adrenergic receptor signaling after left ventricular assist device support
    Prakash K Pandalai
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0558, USA
    J Thorac Cardiovasc Surg 131:975-80. 2006
    ....
  11. ncbi request reprint Simplified treatment of postoperative mediastinitis
    Walter H Merrill
    Department of Surgery and Heart and Vascular Center, Section of Cardiothoracic Surgery, University of Cincinnati, Cincinnati, OH, USA
    Ann Thorac Surg 78:608-12; discussion 608-12. 2004
    ..A variety of treatment plans have been advocated, and there is lack of agreement regarding the best treatment method. We present our results in patients with mediastinitis who have been treated in a simple, consistent manner...
  12. ncbi request reprint Role of the beta-adrenergic receptor kinase in myocardial dysfunction after brain death
    Prakash K Pandalai
    Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 46267 0558, USA
    J Thorac Cardiovasc Surg 130:1183-9. 2005
    ..This study investigates our hypothesis that brain death causes acute activation of the betaAR kinase and leads to desensitization of myocardial beta-adrenergic receptors and impaired ventricular function...
  13. ncbi request reprint Strongyloides hyperinfection syndrome after heart transplantation: case report and review of the literature
    Michael W Schaeffer
    Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Heart Lung Transplant 23:905-11. 2004
    ..Pretransplant evaluation for parasitic infections, including strongyloidiasis, should occur in endemic areas or in patients at risk for occult infestation...

Research Grants1

  1. Myocardial Regulation of betaARK1 by Protein Kinase C
    SHAHAB AKHTER; Fiscal Year: 2007
    ..abstract_text> ..