Research Topics
Genomes and GenesSpecies | Nassima Ait-DaoudSummaryAffiliation: University of Virginia Country: USA Publications
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Publications
An overview of medications for the treatment of alcohol withdrawal and alcohol dependence with an emphasis on the use of older and newer anticonvulsantsNassima Ait-Daoud
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Addict Behav 31:1628-49. 2006..Furthermore, as a class of medication, there appears to be a growing interest in investigating the utility of novel anticonvulsants such as topiramate for the treatment of alcohol dependence...
Can serotonin transporter genotype predict craving in alcoholism?Nassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 33:1329-35. 2009....- Comorbid alcohol and nicotine dependence: from the biomolecular basis to clinical consequencesNassima Ait-Daoud
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
Alcohol Clin Exp Res 29:1541-9. 2005..Lesch, MD, PhD; and (5) Pharmacotherapy for Promotion of Abstinence from Nicotine Among Alcohol-Dependent Individuals, by Bankole A. Johnson, DSc, MD, PhD... - Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinkingBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Am J Psychiatry 168:265-75. 2011.... - Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individualsBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:123-30. 2007..Topiramate's complicated cognitive effects among methamphetamine addicts need more comprehensive examination... - Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studiesBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Am J Hypertens 18:813-22. 2005..We therefore examined, in two separate experiments of similar design conducted contemporaneously, the hemodynamic effects of cocaine or methamphetamine in the presence and absence of isradipine... - Effects of acute topiramate dosing on methamphetamine-induced subjective moodBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 10:85-98. 2007..Thus, testing chronically administered or higher doses, or both, of topiramate would be necessary to determine conclusively whether or not it can attenuate the positive subjective and reinforcing effects of methamphetamine... - Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individualsBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 8:549-56. 2005..Hence, cocaine-taking by cocaine-dependent individuals produces little improvement in cognitive performance and attention in either the presence or absence of isradipine... - Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking?Bankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 32:209-16. 2008..Thus, 5-HTT expression varies with current and lifetime drinking in L-carriers alone... - A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of cocaine dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Drug Alcohol Depend 84:256-63. 2006..04). These results suggest the possibility of a non-linear dose-response function, with evidence supporting efficacy for the 4.0 mg group... - Kinetic and cardiovascular effects of acute topiramate dosing among non-treatment-seeking, methamphetamine-dependent individualsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:455-61. 2007..Larger laboratory studies with chronic dosing regimens are needed to establish whether or not there is a kinetic interaction between topiramate and methamphetamine... - Topiramate for treating alcohol dependence: a randomized controlled trialBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908, USA
JAMA 298:1641-51. 2007.... - Use of oral topiramate to promote smoking abstinence among alcohol-dependent smokers: a randomized controlled trialBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
Arch Intern Med 165:1600-5. 2005..Herein, we extend that proof-of-concept study by determining whether cigarette-smoking, alcohol-dependent individuals from the earlier study also experienced improved smoking outcomes... - Acute intravenous low- and high-dose cocaine reduces quantitative global and regional cerebral blood flow in recently abstinent subjects with cocaine use disorderBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
J Cereb Blood Flow Metab 25:928-36. 2005..Increasingly larger doses of cocaine may be associated with greater risk for ischemic stroke... - Characterization of a functional polymorphism in the 3' UTR of SLC6A4 and its association with drinking intensityChamindi Seneviratne
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA 22911, USA
Alcohol Clin Exp Res 33:332-9. 2009.... - Preliminary Evidence for cue-induced Alcohol Craving Modulated by Serotonin Transporter Gene Polymorphism rs1042173Nassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Charlottesville, VA, USA
Front Psychiatry 3:6. 2012.... - Review of treatment for cocaine dependenceJennifer K Penberthy
Department of Psychiatry and Neurobehavioral Sciences, Center for Addiction Research and Education, P O Box 800623, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Curr Drug Abuse Rev 3:49-62. 2010..More research is necessary to test treatment programs and garner further information in order to better understand and treat cocaine dependence... - Evaluating readiness and treatment seeking effects in a pharmacotherapy trial for alcohol dependenceJ Kim Penberthy
Center for Addiction Research and Education, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 31:1538-44. 2007..Our goal was to evaluate drinking behavior before initiating a randomized, double-blind pharmacotherapy clinical trial for alcohol dependence... - Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patientsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Curr Pharm Des 16:2103-12. 2010..Preclinical information that topiramate may have differential effects based on genetic vulnerability opens up the possibility of future methods to optimize treatment... - Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependenceChamindi Seneviratne
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22911, USA
Neuropsychopharmacology 34:2442-9. 2009..Additional studies are needed to replicate these results in other samples and to elucidate the mechanism(s) by which these polymorphisms affect NK1R function in the brain... - A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of methamphetamine dependenceBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 11:1-14. 2008..These findings should be viewed in light of the possibility that a less intensive cognitive behavioural therapy regimen might have yielded more positive results in this initial phase II trial exploring for the efficacy of ondansetron... - Treating smoking dependence in depressed alcoholicsNassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia, USA
Alcohol Res Health 29:213-20. 2006..Additional treatment strategies targeting dually dependent individuals with comorbid psychiatric disorders, including special populations such as women and adolescents, await further investigation... - Kinetic and cardiovascular comparison of immediate-release isradipine and sustained-release isradipine among non-treatment-seeking, cocaine-dependent individualsBankole A Johnson
South Texas Addiction Research and Technology Center, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
Prog Neuropsychopharmacol Biol Psychiatry 29:15-20. 2005..The more favorable cardiovascular profile of SR isradipine would, however, make it more appropriate as an investigational medication for the treatment of stimulant dependence and related neurovascular disorders... - Effects of isradipine, a dihydropyridine-class calcium-channel antagonist, on d-methamphetamine's subjective and reinforcing effectsBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Int J Neuropsychopharmacol 8:203-13. 2005..Depending upon conditioning status, isradipine can reduce some methamphetamine-induced positive subjective and reinforcing effects associated with its abuse liability in methamphetamine addicts... 
Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trialBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Arch Intern Med 168:1188-99. 2008..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...- Understanding and treating alcohol dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 30:567-84. 2006..Johnson, DSc, MD, PhD; and (5) Differential Effects of Pharmacological Agents on Craving, by Nassima Ait-Daoud, MD... - "Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humansErik W Gunderson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908, USA
Am J Addict 21:320-6. 2012..Biopsychosocial factors associated with SC initiation and usage by the cases help to shed light on psychopharmacologic, clinical, and public health aspects of SC product consumption...