Brahim Aissani

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc A Simple PCR-RFLP Method for Genetic Phase Determination in Compound Heterozygotes
    Rodney T Perry
    Department of Epidemiology, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 2:108. 2011
  2. pmc Multiple hits for the association of uterine fibroids on human chromosome 1q43
    Brahim Aissani
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    PLoS ONE 8:e58399. 2013
  3. pmc The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 52:170-9. 2009
  4. pmc Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e13384. 2010
  5. pmc Host genetics and HIV-1 viral load set-point in African-Americans
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    AIDS 23:673-7. 2009
  6. pmc Structure of tumor necrosis factor-alpha haploblocks in European populations
    Aimee M Merino
    Department of Medicine, University of Alabama, Birmingham, AL, USA
    Immunogenetics 65:543-52. 2013
  7. pmc A candidate gene approach for virally induced cancer with application to HIV-related Kaposi's sarcoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama, Birmingham, AL
    Int J Cancer 134:397-404. 2014
  8. pmc The utility of mitochondrial and y chromosome phylogenetic data to improve correction for population stratification
    Robert Makowsky
    Department of Biostatistics, School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:301. 2012
  9. ncbi request reprint Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 16:1626-32. 2007
  10. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011

Detail Information

Publications12

  1. pmc A Simple PCR-RFLP Method for Genetic Phase Determination in Compound Heterozygotes
    Rodney T Perry
    Department of Epidemiology, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 2:108. 2011
    ..We show that the A allele of TNF -308 is carried on the same chromosome as the LTA +252(G) allele...
  2. pmc Multiple hits for the association of uterine fibroids on human chromosome 1q43
    Brahim Aissani
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    PLoS ONE 8:e58399. 2013
    ..With the high potential for occult tumors in common conditions such as fibroids, validation of our data in family-based studies is needed...
  3. pmc The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 52:170-9. 2009
    ..Which gene variant on this highly conserved extended haplotype (CEH 8.1) in whites most likely represents a true etiologic factor remains uncertain...
  4. pmc Interleukin-10 (IL-10) pathway: genetic variants and outcomes of HIV-1 infection in African American adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 5:e13384. 2010
    ....
  5. pmc Host genetics and HIV-1 viral load set-point in African-Americans
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    AIDS 23:673-7. 2009
    ..We attempted to confirm this finding in African-Americans and to address whether these SNPs are in linkage disequilibrium with human leukocyte antigen (HLA) class I alleles that mediate innate and adaptive immunity...
  6. pmc Structure of tumor necrosis factor-alpha haploblocks in European populations
    Aimee M Merino
    Department of Medicine, University of Alabama, Birmingham, AL, USA
    Immunogenetics 65:543-52. 2013
    ..We also found that the ancestral haplotype 8.1 shares a TNF block haplotype with HLA-B*4402. HLA-B*5701, a known protective allele in HIV-1 pathogenesis, occurred in a unique TNF block haplotype...
  7. pmc A candidate gene approach for virally induced cancer with application to HIV-related Kaposi's sarcoma
    Brahim Aissani
    Department of Epidemiology, University of Alabama, Birmingham, AL
    Int J Cancer 134:397-404. 2014
    ..This "proof of concept" study identified human homologs involved in the regulation of type I interferon-induced signaling, cell cycle and apoptosis potentially as important determinants of HIV-KS...
  8. pmc The utility of mitochondrial and y chromosome phylogenetic data to improve correction for population stratification
    Robert Makowsky
    Department of Biostatistics, School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:301. 2012
    ....
  9. ncbi request reprint Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents
    Sadeep Shrestha
    Department of Epidemiology, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 16:1626-32. 2007
    ....
  10. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011
    ....
  11. doi request reprint Association test of multiallelic gene copy numbers in family trios
    Sadeep Shrestha
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Genet Epidemiol 34:2-6. 2010
    ..We present theoretical derivation of the statistics and results of simulation studies that show robustness of our approach and power under several genetic models...

Research Grants1

  1. Genetic Determinants of Uterine Fibroids in African-American and Caucasian Women
    Brahim Aissani; Fiscal Year: 2010
    ..The knowledge to be gained from this study could, at some point in the near future, lead to the development of the first genetic counseling protocol for fibroids and ultimately to a more appropriate therapy. ..