Dennis J Ahnen

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. ncbi Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
  2. ncbi The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?
    Dennis J Ahnen
    Denver Department of Veterans Affairs Medical Center, University of Colorado Denver School of Medicine, Denver, Colorado 80220, USA
    Am J Gastroenterol 106:190-8. 2011
  3. ncbi Effect of a mailed brochure on appointment-keeping for screening colonoscopy: a randomized trial
    Thomas D Denberg
    University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80262, USA
    Ann Intern Med 145:895-900. 2006
  4. ncbi Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor
    Heather A Pangburn
    UES, Inc, 4401 Dayton Xenia Road, Dayton, OH 45432, USA
    Cancer Prev Res (Phila) 3:560-72. 2010
  5. ncbi Predictors of nonadherence to screening colonoscopy
    Thomas D Denberg
    Department of Medicine, University of Colorado at Denver and Health Sciences, Denver, Colo 80262, USA
    J Gen Intern Med 20:989-95. 2005
  6. ncbi Significance of serrated polyps of the colon
    Rachel J Groff
    University of Colorado Denver School of Medicine, Denver, CO 80220, USA
    Curr Gastroenterol Rep 10:490-8. 2008
  7. ncbi Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
  8. ncbi Clinical practice. Adenomatous polyps of the colon
    Joel S Levine
    University of Colorado School of Medicine, Denver, USA
    N Engl J Med 355:2551-7. 2006
  9. ncbi Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004
  10. ncbi Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
    Pamela L Rice
    Division of Gastroenterology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cancer Res 63:616-20. 2003

Collaborators

Detail Information

Publications11

  1. ncbi Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
    ..Familial colorectal cancer has been linked to chromosome 7q31 by multiple affected relative pair studies. The MET proto-oncogene which resides in this chromosomal region is considered a candidate for genetic susceptibility...
  2. ncbi The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?
    Dennis J Ahnen
    Denver Department of Veterans Affairs Medical Center, University of Colorado Denver School of Medicine, Denver, Colorado 80220, USA
    Am J Gastroenterol 106:190-8. 2011
    ....
  3. ncbi Effect of a mailed brochure on appointment-keeping for screening colonoscopy: a randomized trial
    Thomas D Denberg
    University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80262, USA
    Ann Intern Med 145:895-900. 2006
    ..Often, primary care physicians lack sufficient time to educate patients and address their potential misconceptions and fears about this procedure...
  4. ncbi Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor
    Heather A Pangburn
    UES, Inc, 4401 Dayton Xenia Road, Dayton, OH 45432, USA
    Cancer Prev Res (Phila) 3:560-72. 2010
    ..Thus, sulindac metabolite-induced downregulation of EGFR seems to be mediated through mechanism(s) similar, at least in part, to those involved in EGF-induced downregulation of EGFR...
  5. ncbi Predictors of nonadherence to screening colonoscopy
    Thomas D Denberg
    Department of Medicine, University of Colorado at Denver and Health Sciences, Denver, Colo 80262, USA
    J Gen Intern Med 20:989-95. 2005
    ....
  6. ncbi Significance of serrated polyps of the colon
    Rachel J Groff
    University of Colorado Denver School of Medicine, Denver, CO 80220, USA
    Curr Gastroenterol Rep 10:490-8. 2008
    ..Management of serrated neoplasia of the colon includes careful colonoscopy, complete removal of colonic polyps, sampling fields of diminutive polyps of the rectosigmoid, and basing surveillance on histology of removed polyps...
  7. ncbi Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
    ....
  8. ncbi Clinical practice. Adenomatous polyps of the colon
    Joel S Levine
    University of Colorado School of Medicine, Denver, USA
    N Engl J Med 355:2551-7. 2006
  9. ncbi Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004
    ..These results suggest that inhibition of MEK/ERK signaling is necessary for the induction of apoptosis by sulindac metabolites...
  10. ncbi Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
    Pamela L Rice
    Division of Gastroenterology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cancer Res 63:616-20. 2003
    ..The ability of sulindac to block ERK1/2 signaling by the EGF receptor may account for at least part of its potent growth-inhibitory effects against cancer cells...
  11. ncbi First-degree relatives of patients with advanced colorectal adenomas have an increased prevalence of colorectal cancer
    Kathryn L Lynch
    Department of Medicine and Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Clin Gastroenterol Hepatol 1:96-102. 2003
    ..Individuals with advanced colorectal adenomas should be counseled about the increased risk of colorectal cancer among their relatives...