Dennis J Ahnen

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. doi request reprint The increasing incidence of young-onset colorectal cancer: a call to action
    Dennis J Ahnen
    Department of Veterans Affairs, Eastern Colorado Healthcare System, and Division of Gastroenterology, University of Colorado School of Medicine, Denver Electronic address
    Mayo Clin Proc 89:216-24. 2014
  2. pmc Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
  3. doi request reprint The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?
    Dennis J Ahnen
    Denver Department of Veterans Affairs Medical Center, University of Colorado Denver School of Medicine, Denver, Colorado 80220, USA
    Am J Gastroenterol 106:190-8. 2011
  4. ncbi request reprint Effect of a mailed brochure on appointment-keeping for screening colonoscopy: a randomized trial
    Thomas D Denberg
    University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80262, USA
    Ann Intern Med 145:895-900. 2006
  5. doi request reprint Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor
    Heather A Pangburn
    UES, Inc, 4401 Dayton Xenia Road, Dayton, OH 45432, USA
    Cancer Prev Res (Phila) 3:560-72. 2010
  6. pmc Predictors of nonadherence to screening colonoscopy
    Thomas D Denberg
    Department of Medicine, University of Colorado at Denver and Health Sciences, Denver, Colo 80262, USA
    J Gen Intern Med 20:989-95. 2005
  7. pmc Significance of serrated polyps of the colon
    Rachel J Groff
    University of Colorado Denver School of Medicine, Denver, CO 80220, USA
    Curr Gastroenterol Rep 10:490-8. 2008
  8. ncbi request reprint Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
  9. ncbi request reprint Clinical practice. Adenomatous polyps of the colon
    Joel S Levine
    University of Colorado School of Medicine, Denver, USA
    N Engl J Med 355:2551-7. 2006
  10. ncbi request reprint Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004

Collaborators

Detail Information

Publications13

  1. doi request reprint The increasing incidence of young-onset colorectal cancer: a call to action
    Dennis J Ahnen
    Department of Veterans Affairs, Eastern Colorado Healthcare System, and Division of Gastroenterology, University of Colorado School of Medicine, Denver Electronic address
    Mayo Clin Proc 89:216-24. 2014
    ..Early screening in high-risk individuals and thorough diagnostic work-ups in symptomatic young adults may improve young-onset CRC trends. ..
  2. pmc Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
    ..Familial colorectal cancer has been linked to chromosome 7q31 by multiple affected relative pair studies. The MET proto-oncogene which resides in this chromosomal region is considered a candidate for genetic susceptibility...
  3. doi request reprint The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?
    Dennis J Ahnen
    Denver Department of Veterans Affairs Medical Center, University of Colorado Denver School of Medicine, Denver, Colorado 80220, USA
    Am J Gastroenterol 106:190-8. 2011
    ....
  4. ncbi request reprint Effect of a mailed brochure on appointment-keeping for screening colonoscopy: a randomized trial
    Thomas D Denberg
    University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80262, USA
    Ann Intern Med 145:895-900. 2006
    ..Often, primary care physicians lack sufficient time to educate patients and address their potential misconceptions and fears about this procedure...
  5. doi request reprint Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor
    Heather A Pangburn
    UES, Inc, 4401 Dayton Xenia Road, Dayton, OH 45432, USA
    Cancer Prev Res (Phila) 3:560-72. 2010
    ..Thus, sulindac metabolite-induced downregulation of EGFR seems to be mediated through mechanism(s) similar, at least in part, to those involved in EGF-induced downregulation of EGFR...
  6. pmc Predictors of nonadherence to screening colonoscopy
    Thomas D Denberg
    Department of Medicine, University of Colorado at Denver and Health Sciences, Denver, Colo 80262, USA
    J Gen Intern Med 20:989-95. 2005
    ....
  7. pmc Significance of serrated polyps of the colon
    Rachel J Groff
    University of Colorado Denver School of Medicine, Denver, CO 80220, USA
    Curr Gastroenterol Rep 10:490-8. 2008
    ..Management of serrated neoplasia of the colon includes careful colonoscopy, complete removal of colonic polyps, sampling fields of diminutive polyps of the rectosigmoid, and basing surveillance on histology of removed polyps...
  8. ncbi request reprint Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
    ....
  9. ncbi request reprint Clinical practice. Adenomatous polyps of the colon
    Joel S Levine
    University of Colorado School of Medicine, Denver, USA
    N Engl J Med 355:2551-7. 2006
  10. ncbi request reprint Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004
    ..These results suggest that inhibition of MEK/ERK signaling is necessary for the induction of apoptosis by sulindac metabolites...
  11. ncbi request reprint Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
    Pamela L Rice
    Division of Gastroenterology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cancer Res 63:616-20. 2003
    ..The ability of sulindac to block ERK1/2 signaling by the EGF receptor may account for at least part of its potent growth-inhibitory effects against cancer cells...
  12. pmc Familial colon cancer syndromes: an update of a rapidly evolving field
    Swati G Patel
    University of Colorado School of Medicine, Aurora, CO 80045, USA
    Curr Gastroenterol Rep 14:428-38. 2012
    ..Advances within the area of hereditary colon cancer syndromes paint a picture of a rapidly moving, rapidly maturing, and increasingly collaborative field with many opportunities for ongoing research and development...
  13. ncbi request reprint First-degree relatives of patients with advanced colorectal adenomas have an increased prevalence of colorectal cancer
    Kathryn L Lynch
    Department of Medicine and Preventive Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado, USA
    Clin Gastroenterol Hepatol 1:96-102. 2003
    ..This study assessed whether finding colonic neoplasia during screening colonoscopy was related to the family history of colorectal cancer among the participants' parents and siblings...