- Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblastsSalahuddin Ahmed
Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Health Science Campus, Toledo, OH 43614, USA
Toxicol Appl Pharmacol 270:87-96. 2013..Understanding the exact role of different HDAC isoenzymes in RA pathogenesis is extremely important in order to develop highly effective HDAC inhibitors for the treatment of RA...
- Green tea polyphenol epigallocatechin 3-gallate in arthritis: progress and promiseSalahuddin Ahmed
Department of Pharmacology, 2232 Wolfe Hall, College of Pharmacy, 2801 W, Bancroft Street, Toledo, OH 43606, USA
Arthritis Res Ther 12:208. 2010..Although these findings provide scientific evidence of the anti-rheumatic activity of EGCG, further preclinical studies are warranted before phase clinical trials could be initiated with confidence for patients with joint diseases...