A Ahmed

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Prospective population studies of incident heart failure without data on baseline left ventricular ejection fraction
    Marjan Mujib
    University of Alabama at Birmingham, Birmingham, AL, USA
    Arch Med Sci 6:686-8. 2010
  2. pmc Orthostatic hypotension and incident heart failure in community-dwelling older adults
    Kannayiram Alagiakrishnan
    University of Alabama at Birmingham, 1720 2nd Avenue South, CH 19, Suite 219, Birmingham, AL 35294 2041, USA
    J Gerontol A Biol Sci Med Sci 69:223-30. 2014
  3. pmc Digoxin Use and Lower 30-day All-cause Readmission for Medicare Beneficiaries Hospitalized for Heart Failure
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Ala Veterans Affairs Medical Center, Birmingham, Ala Electronic address
    Am J Med 127:61-70. 2014
  4. pmc Renin-angiotensin inhibition in diastolic heart failure and chronic kidney disease
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Med 126:150-61. 2013
  5. pmc Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Am J Med 125:399-410. 2012
  6. ncbi request reprint VALIDD should not invalidate angiotensin-receptor blockers
    Ali Ahmed
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Lancet 369:2053-4. 2007
  7. pmc A propensity-matched study of the association of physical function and outcomes in geriatric heart failure
    Ali Ahmed
    University of Alabama at Birmingham, 1530 3rd Avenue South, CH 19, Ste 219, Birmingham, AL 35294 2041, USA
    Arch Gerontol Geriatr 46:161-72. 2008
  8. pmc A propensity-matched study of the effect of diabetes on the natural history of heart failure: variations by sex and age
    Ali Ahmed
    University of Alabama at Birmingham and VA Medical Center, Birmingham, AL 35294 2041, USA
    Heart 93:1584-90. 2007
  9. pmc Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrations
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham AL 35294 2041, USA
    J Gerontol A Biol Sci Med Sci 62:323-9. 2007
  10. pmc Effects of digoxin at low serum concentrations on mortality and hospitalization in heart failure: a propensity-matched study of the DIG trial
    Ali Ahmed
    University of Alabama at Birmingham, 1530 3rd Ave South, CH 19, Ste 219 and VA Medical Center, Birmingham, AL 35294 2041, USA
    Int J Cardiol 123:138-46. 2008

Detail Information

Publications86

  1. pmc Prospective population studies of incident heart failure without data on baseline left ventricular ejection fraction
    Marjan Mujib
    University of Alabama at Birmingham, Birmingham, AL, USA
    Arch Med Sci 6:686-8. 2010
    ..Using public-use copies of the CHS data, we compared two predictor models of incident HF, with and without adjustment for baseline LVEF...
  2. pmc Orthostatic hypotension and incident heart failure in community-dwelling older adults
    Kannayiram Alagiakrishnan
    University of Alabama at Birmingham, 1720 2nd Avenue South, CH 19, Suite 219, Birmingham, AL 35294 2041, USA
    J Gerontol A Biol Sci Med Sci 69:223-30. 2014
    ..To examine the association of orthostatic hypotension with incident heart failure (HF) in older adults...
  3. pmc Digoxin Use and Lower 30-day All-cause Readmission for Medicare Beneficiaries Hospitalized for Heart Failure
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Ala Veterans Affairs Medical Center, Birmingham, Ala Electronic address
    Am J Med 127:61-70. 2014
    ..Digoxin reduces 30-day all-cause hospital admission in chronic systolic heart failure. Whether digoxin is effective in reducing readmission after hospitalization for acute decompensation remains unknown...
  4. pmc Renin-angiotensin inhibition in diastolic heart failure and chronic kidney disease
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Med 126:150-61. 2013
    ..The role of renin-angiotensin inhibition in older patients with diastolic heart failure and chronic kidney disease remains unclear...
  5. pmc Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Am J Med 125:399-410. 2012
    ..The role of renin-angiotensin inhibition in older patients with systolic heart failure with chronic kidney disease remains unclear...
  6. ncbi request reprint VALIDD should not invalidate angiotensin-receptor blockers
    Ali Ahmed
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Lancet 369:2053-4. 2007
  7. pmc A propensity-matched study of the association of physical function and outcomes in geriatric heart failure
    Ali Ahmed
    University of Alabama at Birmingham, 1530 3rd Avenue South, CH 19, Ste 219, Birmingham, AL 35294 2041, USA
    Arch Gerontol Geriatr 46:161-72. 2008
    ..11; 95% CI, 0.96-1.29; p=0.150), or worsening HF (HR, 1.09, 95% CI, 0.92-1.30; p=0.330). Baseline NYHA functional class was associated with mortality but not with hospitalization in ambulatory older adults with chronic HF...
  8. pmc A propensity-matched study of the effect of diabetes on the natural history of heart failure: variations by sex and age
    Ali Ahmed
    University of Alabama at Birmingham and VA Medical Center, Birmingham, AL 35294 2041, USA
    Heart 93:1584-90. 2007
    ..Poor prognosis in heart failure (HF) patients with diabetes is often attributed to increased co-morbidity and advanced disease. Further, this effect may be worse in women...
  9. pmc Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrations
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham AL 35294 2041, USA
    J Gerontol A Biol Sci Med Sci 62:323-9. 2007
    ..Most HF patients are > or = 65 years, yet the effects of digoxin on outcomes in these patients have not been well studied...
  10. pmc Effects of digoxin at low serum concentrations on mortality and hospitalization in heart failure: a propensity-matched study of the DIG trial
    Ali Ahmed
    University of Alabama at Birmingham, 1530 3rd Ave South, CH 19, Ste 219 and VA Medical Center, Birmingham, AL 35294 2041, USA
    Int J Cardiol 123:138-46. 2008
    ..However, the effects of digoxin on other cause-specific outcomes have not been studied in a propensity-matched cohort...
  11. pmc A propensity-matched study of the association of low serum potassium levels and mortality in chronic heart failure
    Ali Ahmed
    Department of Medicine, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 2041, USA
    Eur Heart J 28:1334-43. 2007
    ..However, the association of low potassium and long-term mortality and morbidity in heart failure (HF) is largely unknown...
  12. pmc Depression and nursing home admission among hospitalized older adults with coronary artery disease: a propensity score analysis
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, AL, USA
    Am J Geriatr Cardiol 16:76-83. 2007
    ..55; 95% confidence interval, 1.21-1.99). In ambulatory older adults hospitalized with coronary artery disease, a secondary diagnosis of depression was associated with a significantly increased risk of nursing home admission...
  13. pmc The underuse of digoxin in heart failure, and approaches to appropriate use
    Ali Ahmed
    University of Alabama at Birmingham and VA Medical Center, Birmingham, Ala 35294 2041, USA
    CMAJ 176:641-3. 2007
  14. pmc A propensity matched study of New York Heart Association class and natural history end points in heart failure
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 99:549-53. 2007
    ..002), and 1.17 for HF hospitalization (95% CI 1.03 to 1.34, p = 0.017). In conclusion, baseline NYHA class is a marker of hospitalization, disease progression, and mortality in a wide spectrum of ambulatory patients with chronic HF...
  15. pmc Hospitalizations due to unstable angina pectoris in diastolic and systolic heart failure
    Ali Ahmed
    University of Alabama at Birmingham, Alabama, USA
    Am J Cardiol 99:460-4. 2007
    ..As in patients with systolic HF, those with diastolic HF should be routinely evaluated for myocardial ischemia and managed accordingly...
  16. pmc Chronic kidney disease associated mortality in diastolic versus systolic heart failure: a propensity matched study
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 99:393-8. 2007
    ..Patients with diastolic HF should be evaluated for CKD, and the role of inhibitors of the renin-angiotensin system in these patients needs to be investigated...
  17. ncbi request reprint Clinical manifestations, diagnostic assessment, and etiology of heart failure in older adults
    Ali Ahmed
    Department of Medicine, School of Medicine, Geriatric Heart Failure Clinic, Center for Aging, and Center for Heart Failure Research, University of Alabama at Birmingham, 1530 3rd Avenue South, CH19 219, Birmingham, AL 35294 2041, USA
    Clin Geriatr Med 23:11-30. 2007
    ....
  18. ncbi request reprint Geriatric heart failure, depression, and nursing home admission: an observational study using propensity score analysis
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Am J Geriatr Psychiatry 14:867-75. 2006
    ..The objective of this study was to examine the effect of depression on NH admission for older adults with HF...
  19. pmc Effects of discontinuation of digoxin versus continuation at low serum digoxin concentrations in chronic heart failure
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 100:280-4. 2007
    ....
  20. pmc A propensity-matched study of the effects of chronic diuretic therapy on mortality and hospitalization in older adults with heart failure
    Ali Ahmed
    University of Alabama at Birmingham, and Veterans Affairs Medical Center, Birmingham, 1530 3rd Avenue South, CH19 219, Birmingham, Alabama 35294 2041, USA
    Int J Cardiol 125:246-53. 2008
    ..The objective of this propensity-matched study was to determine the effect of diuretics on mortality and hospitalizations in heart failure patients >or=65 years...
  21. pmc Intrinsic association of widowhood with mortality in community-dwelling older women and men: findings from a prospective propensity-matched population study
    Beverly R Williams
    Section of Geriatrics, VA Medical Center, Birmingham, Alabama, USA
    J Gerontol A Biol Sci Med Sci 66:1360-8. 2011
    ..In the current study, we used propensity score matching to design a study to examine the independent association of widowhood with outcomes in a balanced cohort of older adults in the United States...
  22. pmc Chronic heart failure in older adults
    Ali Ahmed
    Division of Gerontology, Department of Medicine, School of Medicine, School of Public Health, Center for Aging, University of Alabama at Birmingham, 1530 3rd Avenue South, CH19 219, Birmingham, AL 35294 2041, USA
    Med Clin North Am 95:439-61, ix. 2011
    ..Left ventricular ejection fraction must be obtained to classify patients into systolic and diastolic HF and to guide evidence-based therapy...
  23. pmc Effectiveness of digoxin in reducing one-year mortality in chronic heart failure in the Digitalis Investigation Group trial
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 103:82-7. 2009
    ..Randomized clinical trials are needed to determine the effect of low-dose digoxin in contemporary patients with chronic HF...
  24. pmc Predictors of in-hospital mortality among hospitalized nursing home residents: an analysis of the National Hospital Discharge Surveys 2005-2006
    Amiya A Ahmed
    Alabama School of Fine Arts, Birmingham, AL, USA
    J Am Med Dir Assoc 11:52-8. 2010
    ..To determine the demographic and clinical predictors of in-hospital mortality among hospitalized nursing home (NH) residents...
  25. pmc Mild hyperkalemia and outcomes in chronic heart failure: a propensity matched study
    Mustafa I Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama 35294 2041, USA
    Int J Cardiol 144:383-8. 2010
    ..Expert opinions suggest that serum potassium levels >5.5 mEq/L may be harmful in HF. However, little is known about the safety of serum potassium 5-5.5 mEq/L...
  26. pmc A history of systemic hypertension and incident heart failure hospitalization in patients with acute myocardial infarction and left ventricular systolic dysfunction
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 103:1374-80. 2009
    ....
  27. pmc DEFEAT - Heart Failure: a guide to management of geriatric heart failure by generalist physicians
    A Ahmed
    Department of Medicine, School of Medicine and Public Health, Geriatric Heart Failure Clinics, University of Alabama at Birmingham, Veterans Affairs Medical Center, Birmingham, AL 35294 2041, USA
    Minerva Med 100:39-50. 2009
    ..Diuretic and digoxin should be prescribed for all symptomatic patients with heart failure. An aldosterone antagonist may be used in select patients with advanced systolic heart failure, carefully avoiding hyperkalemia...
  28. pmc Epidemiology of chronic kidney disease in heart failure
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Heart Fail Clin 4:387-99. 2008
    ..Understanding the epidemiology and outcomes of chronic kidney disease in heart failure is essential to ensure proper management of these patients...
  29. pmc DEFEAT heart failure: assessment and management of heart failure in nursing homes made easy
    Ali Ahmed
    Division of Gerontology, Geriatrics and Palliative Care, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    J Am Med Dir Assoc 9:383-9. 2008
    ..After making a clinical Diagnosis and determining the Etiology, Fluid volume must be assessed to achieve euvolemia, and Ejection frAction must be determined to guide Therapy...
  30. pmc Incident heart failure hospitalization and subsequent mortality in chronic heart failure: a propensity-matched study
    Ali Ahmed
    University of Alabama at Birmingham, and VA Medical Center, Birmingham, Alabama 35294 2041, USA
    J Card Fail 14:211-8. 2008
    ..However, the effect of incident HF hospitalization (compared with no HF hospitalization) on subsequent mortality has not been studied in a propensity-matched population of chronic HF patients...
  31. ncbi request reprint Management of syncope in older adults may require thorough evaluation: a conversation with Dr. Mathew Maurer
    Ali Ahmed
    Division of Gerontology, Geriatrics and Palliative Care, Geriatric Heart Failure Clinic and Center for Heart Failure Research, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Am J Geriatr Cardiol 17:123-4. 2008
  32. ncbi request reprint Increased heart rate: an emerging cardiovascular risk factor in older adults
    Ali Ahmed
    Division of Gerontology, Geriatrics and Palliative Care, Geriatric Heart Failure Clinic, and Center for Heart Failure Research, University of Alabama at Birmingham and VA Medical Center, Birmingham, AL 35294 2401, USA
    Am J Geriatr Cardiol 17:55-6. 2008
  33. ncbi request reprint High blood pressure in older adults: a conversation with Dr David Calhoun
    Ali Ahmed
    Division of Gerontology, Geriatrics and Palliative Care, Geriatric Heart Failure Clinic, and Center for Heart Failure Research, University of Alabama at Birmingham and VA Medical Center, AL 35294 2041, USA
    Am J Geriatr Cardiol 16:391-2. 2007
  34. pmc Effects of digoxin on morbidity and mortality in diastolic heart failure: the ancillary digitalis investigation group trial
    Ali Ahmed
    University of Alabama at Birmingham, 1530 3rd Ave S, CH 19, Suite 219, Birmingham AL 35294 2041, USA
    Circulation 114:397-403. 2006
    ..Although digoxin was tested in an appreciable number of diastolic heart failure patients in the Digitalis Investigation Group ancillary trial, detailed findings from this important study have not previously been published...
  35. pmc Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods
    Ali Ahmed
    Department of Medicine, School of Medicine, and Department of Epidemiology, School of Public Health, and Center for Heart Failure Research, University of Alabama at Birmingham and VA Medical Center, 35294 2041, USA
    Eur Heart J 27:1431-9. 2006
    ..Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes...
  36. ncbi request reprint Impact of atrial fibrillation on mortality and readmission in older adults hospitalized with heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging and Geriatric Heart Failure Clinic, University of Alabama at Birmingham, Birmingham, AL, USA
    Eur J Heart Fail 6:421-6. 2004
    ..Atrial fibrillation is common in older adults with heart failure. It is known to adversely affect outcomes...
  37. pmc Management of diastolic heart failure in older adults
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    BMJ 328:1114. 2004
  38. ncbi request reprint Correlates and outcomes of preserved left ventricular systolic function among older adults hospitalized with heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Ala, USA
    Am Heart J 144:365-72. 2002
    ..The objective of this retrospective follow-up study was to determine the correlates and outcomes of preserved LVSF among older adults hospitalized with HF...
  39. ncbi request reprint Treatment of chronic heart failure in long-term care facilities: implications of recent heart failure guidelines recommendations
    Ali Ahmed
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Arch Gerontol Geriatr 37:131-7. 2003
    ..Appropriate evaluation and management of these patients are essential to improve quality of heart failure care in the coming decades...
  40. ncbi request reprint Predictors of nursing home admission for older adults hospitalized with heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, Schools of Medicine, University of Alabama at Birmingham, 1530 3rd Ave South, CH 19, Ste 219, Birmingham, AL 35294 2041, USA
    Arch Gerontol Geriatr 36:117-26. 2003
    ..Age, length of hospital stay, and diabetes were associated with new nursing home admissions. Further studies are needed to identify modifiable risk factors for nursing home admissions and to develop appropriate interventions...
  41. ncbi request reprint Survival benefits of angiotensin-converting enzyme inhibitors in older heart failure patients with perceived contraindications
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, USA
    J Am Geriatr Soc 50:1659-66. 2002
    ..To determine the association between angiotensin-converting enzyme (ACE) inhibitor therapy and survival of older heart failure patients with conditions perceived by physicians as contraindications to ACE inhibitors...
  42. ncbi request reprint Quality of care of nursing home residents hospitalized with heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama, Birmingham, AL, USA
    J Am Geriatr Soc 50:1831-6. 2002
    ..To determine whether the quality of heart failure (HF) care of hospitalized nursing home (NH) residents is different from that of patients admitted from other locations...
  43. ncbi request reprint Heart failure mortality among older Medicare beneficiaries: association with left ventricular function evaluation and angiotensin-converting enzyme inhibitor use
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, Center for Aging, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    South Med J 96:124-9. 2003
    ..In this retrospective follow-up study, we analyzed the association between these two quality indicators and mortality in elderly hospitalized heart failure patients...
  44. ncbi request reprint Clinical correlates of isolated left ventricular diastolic dysfunction among hospitalized older heart failure patients
    Ali Ahmed
    Division of Gerontology, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Geriatr Cardiol 12:82-9. 2003
    ..Except for female sex and systolic blood pressure, all model variables were negatively associated with isolated LVDD...
  45. ncbi request reprint Telomeres, telomerase, and telomerase inhibition: clinical implications for cancer
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham and Heart Failure Clinic and Section of Gerontology, VA Medical Center, Birmingham, Alabama 35294 2041, USA
    J Am Geriatr Soc 51:116-22. 2003
    ..As the knowledge of the relationships between telomerase and cancer and between telomerase and aging advances, it is hoped that more about the interacting relationships between telomerase, aging, and cancer will be learned...
  46. ncbi request reprint American College of Cardiology/American Heart Association Chronic Heart Failure Evaluation and Management guidelines: relevance to the geriatric practice
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, School of Medicine, University of Alabama at Birmingham and Heart Failure Clinic and Section of Gerontology, VA Medical Center, Birmingham, Alabama 35294 2041, USA
    J Am Geriatr Soc 51:123-6. 2003
    ..Beta-blockers were reserved for HF patients after acute myocardial infarctions. Recent advances in the management of HF called for a revision of the guidelines...
  47. ncbi request reprint Telomerase, telomerase inhibition, and cancer
    Ali Ahmed
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Anti Aging Med 6:315-25. 2003
    ..Elucidation of the control of telomerase in aging and in cancer as an age-related disease has considerable potential in leading to novel approaches in anti-aging medicine...
  48. ncbi request reprint Racial variations in cardiology care among hospitalized older heart failure patients
    Ali Ahmed
    Department of Medicine, University of Alabama at Birmingham UAB, AL 35294 2041, USA
    Heart Dis 5:8-14. 2003
    ..43; 95% CI = 0.30-0.62). These findings suggest that nonwhite elderly hospitalized heart failure patients are less likely to be cared for by cardiologists...
  49. pmc Higher New York Heart Association classes and increased mortality and hospitalization in patients with heart failure and preserved left ventricular function
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama, Birmingham, AL, USA
    Am Heart J 151:444-50. 2006
    ..The association between higher New York Heart Association (NYHA) class and outcomes in patients with heart failure and preserved systolic function is not well known...
  50. pmc Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial
    Ali Ahmed
    University of Alabama at Birmingham, VA Medical Center, 1530 3rd Avenue South, CH 19, Ste 219, Birmingham, AL 35294 2041, USA
    Eur Heart J 27:178-86. 2006
    ..To determine the effects of digoxin on all-cause mortality and heart failure (HF) hospitalizations, regardless of ejection fraction, accounting for serum digoxin concentration (SDC)...
  51. ncbi request reprint Myocardial beta-1 adrenoceptor down-regulation in aging and heart failure: implications for beta-blocker use in older adults with heart failure
    Ali Ahmed
    Divisions of Gerontology and Geriatric Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, CH19 219, Birmingham, AL 35294 2041, USA
    Eur J Heart Fail 5:709-15. 2003
    ....
  52. ncbi request reprint Incident atrial fibrillation and mortality in older adults with heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Birmingham, AL 35294, USA
    Eur J Heart Fail 7:1118-21. 2005
    ..22-2.03). After adjustment for other covariates the association remained unchanged (adjusted hazard ratio, 1.41; 95% confidence interval, 1.08-1.83). Past or chronic atrial fibrillation was not associated with increased risk of death...
  53. pmc Serum digoxin concentration and outcomes in women with heart failure: A bi-directional effect and a possible effect modification by ejection fraction
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Eur J Heart Fail 8:409-19. 2006
    ..The association between serum digoxin concentration (SDC) and outcomes in women with heart failure (HF) has not been well studied...
  54. pmc Association of diastolic dysfunction and outcomes in ambulatory older adults with chronic heart failure
    Ali Ahmed
    Geriatric Heart Failure Clinic, and Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Alabama at Birmingham, 35294, USA
    J Gerontol A Biol Sci Med Sci 60:1339-44. 2005
    ..Studies of patients with heart failure and preserved systolic function report variable outcomes compared with those of patients with impaired systolic function...
  55. ncbi request reprint A propensity score analysis of the impact of angiotensin-converting enzyme inhibitors on long-term survival of older adults with heart failure and perceived contraindications
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, University of Alabama at Birmingham, Birmingham, Ala 35294 2041, USA
    Am Heart J 149:737-43. 2005
    ....
  56. ncbi request reprint Interaction between aspirin and angiotensin-converting enzyme inhibitors: should they be used together in older adults with heart failure?
    Ali Ahmed
    Division of Gerontology Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, 35294, USA
    J Am Geriatr Soc 50:1293-6. 2002
    ....
  57. ncbi request reprint Use of angiotensin-converting enzyme inhibitors in patients with heart failure and renal insufficiency: how concerned should we be by the rise in serum creatinine?
    Ali Ahmed
    Division of Gerontology Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, 35294, USA
    J Am Geriatr Soc 50:1297-300. 2002
    ....
  58. pmc Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease: findings from propensity-matched studies
    C Barrett Bowling
    Section of Geriatrics, VA Medical Center, Birmingham, Ala, USA
    Circ Heart Fail 3:253-60. 2010
    ..Little is known about the effects of hypokalemia on outcomes in patients with chronic heart failure (HF) and chronic kidney disease...
  59. pmc Effects of angiotensin-converting enzyme inhibitors in systolic heart failure patients with chronic kidney disease: a propensity score analysis
    Ali Ahmed
    Department of Medicine, School of Medicine, and Center for Heart Failure Research, University of Alabama at Birmingham, 35294 2041, USA
    J Card Fail 12:499-506. 2006
    ..The objective of this analysis was to determine if ACE inhibitor use was associated with reduction in mortality and hospitalization in SHF-CKD patients...
  60. ncbi request reprint Age-related underutilization of angiotensin-converting enzyme inhibitors in older hospitalized heart failure patients
    Ali Ahmed
    Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
    South Med J 95:703-10. 2002
    ..The extent to which age plays a role in the underutilization of angiotensin-converting enzyme (ACE) inhibitors in heart failure patients has not been well studied...
  61. pmc Outcomes in ambulatory chronic systolic and diastolic heart failure: a propensity score analysis
    Ali Ahmed
    University of Alabama at Birmingham and VA Medical Center, Birmingham, AL 35294 2041, USA
    Am Heart J 152:956-66. 2006
    ..In this analysis, we examined long-term mortality and hospitalization in a propensity score matched cohort of ambulatory chronic systolic and diastolic HF patients...
  62. pmc Multimorbidity due to diabetes mellitus and chronic kidney disease and outcomes in chronic heart failure
    O James Ekundayo
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Cardiol 103:88-92. 2009
    ..26 (95% CI 1.03 to 1.55, p = 0.026). In conclusion, compared with co-morbidity due to DM alone, the presence of multimorbidity due to DM and CKD was associated with increased mortality and morbidity in patients with chronic HF...
  63. ncbi request reprint Age-related underutilization of left ventricular function evaluation in older heart failure patients
    Ali Ahmed
    Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
    South Med J 95:695-702. 2002
    ..Underutilization of left ventricular function (LVF) evaluation in older patients with heart failure has been well documented, but age-related variation in the use of LVF evaluation has not been...
  64. doi request reprint Prospective study of risk factors for hepatitis C virus acquisition by Caucasian, Hispanic, and Asian American patients
    E Y Ho
    Department of Medicine, Stanford University Medical Center, Palo Alto, CA 94304, USA
    J Viral Hepat 19:e105-11. 2012
    ..These findings may guide the development of HCV screening in our increasingly diverse population...
  65. ncbi request reprint Association of consultation between generalists and cardiologists with quality and outcomes of heart failure care
    Ali Ahmed
    aDivision of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging, University of Alabama at Birmingham, USA
    Am Heart J 145:1086-93. 2003
    ..The objective of this retrospective cohort study was to determine whether consultation between generalists and cardiologists was associated with better quality and outcomes of HF care...
  66. pmc Isolated systolic hypertension and incident heart failure in older adults: a propensity-matched study
    O James Ekundayo
    University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Hypertension 53:458-65. 2009
    ..In conclusion, in a propensity-matched cohort of community-dwelling older adults who were well balanced in 64 baseline covariates, ISH was associated with increased risk of incident HF but had no association with all-cause mortality...
  67. pmc Predictors of mortality and hospitalization in women with heart failure in the Digitalis Investigation Group trial
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, Center for Aging and Geriatric Heart Failure Clinic, University of Alabama at Birmingham, Alabama, USA
    Am J Ther 13:325-31. 2006
    ....
  68. doi request reprint Transarterial chemoinfusion for hepatocellular carcinoma as downstaging therapy and a bridge toward liver transplantation
    W De Luna
    Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Am J Transplant 9:1158-68. 2009
    ....
  69. ncbi request reprint Use of beta-blockers in older adults with chronic heart failure
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Med Sci 328:100-11. 2004
    ..It is likely that lower doses of beta-blockers are as effective as higher doses...
  70. ncbi request reprint Diagnosis of heart failure in older adults: predictive value of dyspnea at rest
    Ali Ahmed
    Department of Medicine, New York Medical College, Valhalla, NY 10595, USA
    Arch Gerontol Geriatr 38:297-307. 2004
    ..Dyspnea at rest was the commonest symptom among elderly hospitalized HF patients and had high sensitivity, but low specificity and positive predictive value, which increased in the presence of other symptoms...
  71. pmc Uncontrolled hypertension and increased risk for incident heart failure in older adults with hypertension: findings from a propensity-matched prospective population study
    Anand S Iyer
    University of Alabama at Birmingham, Birmingham, AL, USA
    J Am Soc Hypertens 4:22-31. 2010
    ..0001), respectively. In community-dwelling older adults with hypertension, those with uncontrolled (versus controlled) BP have increased risk of new-onset HF, which is more pronounced in those with SBP > or =160 mm Hg and with CKD...
  72. ncbi request reprint Inappropriate use of digoxin in older hospitalized heart failure patients
    Ali Ahmed
    Division of Gerontology and Geriatric Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, USA
    J Gerontol A Biol Sci Med Sci 57:M138-43. 2002
    ..Studies have described the inappropriate use of digoxin in various populations. The objective of this study was to determine the correlates of inappropriate digoxin use in older heart failure patients...
  73. doi request reprint A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
    Marc A Pfeffer
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 361:2019-32. 2009
    ..Although darbepoetin alfa can effectively increase hemoglobin levels, its effect on clinical outcomes in these patients has not been adequately tested...
  74. ncbi request reprint Telomeres and telomerase: basic science implications for aging
    A Ahmed
    Division of Gerontology and Geriatric Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Am Geriatr Soc 49:1105-9. 2001
    ....
  75. ncbi request reprint Review article: the epidemiology and therapy of chronic hepatitis C genotypes 4, 5 and 6
    J M Wantuck
    Department of Medicine, Stanford University Medical Center, Palo Alto, CA, USA
    Aliment Pharmacol Ther 39:137-47. 2014
    ..The literature on these genotypes is sparse and this synopsis will review characteristics of patients infected with these genotypes...
  76. ncbi request reprint Proximal renal tubular acidosis associated with osteomalacia
    A Ahmed
    Department of Medicine, University of Alabama at Birmingham School of Medicine, Veterans Affairs Medical Center, 35294-2041, USA
    South Med J 94:536-9. 2001
    ..Treatment with vitamin D and a calcium supplement led to normalization of laboratory values...
  77. pmc Isolated diastolic hypotension and incident heart failure in older adults
    Jason L Guichard
    University of Alabama at Birmingham, Birmingham, AL 35294 2041, USA
    Hypertension 58:895-901. 2011
    ..09-1.53; P=0.003). As in isolated systolic hypertension, among community-dwelling older adults without prevalent heart failure, isolated diastolic hypotension is also a significant independent risk factor for incident heart failure...
  78. ncbi request reprint Depression in older adults with heart failure
    Ali Ahmed
    J Am Coll Cardiol 44:2254; author reply 2255-6. 2004
  79. ncbi request reprint Heart failure with preserved ejection fraction
    Ali Ahmed
    N Engl J Med 355:1829-30; author reply 1830-1. 2006
  80. pmc Race and the natural history of chronic heart failure: a propensity-matched study
    Giovanni Gambassi
    Universita Cattolica del Sacro Cuore, Rome, Italy
    J Card Fail 14:373-8. 2008
    ....
  81. ncbi request reprint Angiotensin-converting enzyme inhibitors, beta-blockers, and mortality in systolic heart failure
    Phillip L Thornton
    J Am Coll Cardiol 43:1333; author reply 1333-4. 2004
  82. pmc A propensity-matched study of the association of cardiothoracic ratio with morbidity and mortality in chronic heart failure
    Grigorios Giamouzis
    Emory University, Atlanta, Georgia, USA
    Am J Cardiol 101:343-7. 2008
    ..27 (95% CI 1.13 to 1.44, p<0.0001) for HF hospitalization. In conclusion, a baseline CTR>0.50 was associated with increased mortality and morbidity in ambulatory patients with chronic HF...
  83. ncbi request reprint Sex-related difference in long-term mortality in elderly heart failure patients with preserved left ventricular systolic function
    Ali Ahmed
    J Gerontol A Biol Sci Med Sci 58:671-2; author reply 672. 2003
  84. pmc A propensity-matched study of hypertension and increased stroke-related hospitalization in chronic heart failure
    Gerasimos S Filippatos
    University of Athens, Athens, Greece
    Am J Cardiol 101:1772-6. 2008
    ..81; p=0.044). In conclusion, a history of hypertension was associated with increased risk of hospitalization for stroke among patients with heart failure who were balanced in all measured baseline covariates, including blood pressure...
  85. pmc History of hypertension and eplerenone in patients with acute myocardial infarction complicated by heart failure
    Bertram Pitt
    University of Michigan, 1500 E Medical Center Dr, 3910 Taubman Center, Ann Arbor, MI 48109 0366, USA
    Hypertension 52:271-8. 2008
    ..91; 95% CI: 0.76 to 1.10; P=0.331). Eplerenone should, therefore, be prescribed to all of the post-acute myocardial infarction patients with reduced left ventricular ejection fraction and heart failure regardless of Hx-HTN...
  86. ncbi request reprint Gender differences in resistance-training-induced myofiber hypertrophy among older adults
    Marcas M Bamman
    Geriatric Research, Education, and Clinical Center, VA Medical Center, Birmingham, Alabama, USA
    J Gerontol A Biol Sci Med Sci 58:108-16. 2003
    ..05). In summary, gender differences in load-induced myofiber hypertrophy among older adults cannot be explained by levels of circulating IGF-1 or dehydroepiandrosterone sulfate, or by expression of the myogenic transcripts examined...

Research Grants8

  1. Heart Failure and Beta-Blocker Use in Older Adults
    Ali Ahmed; Fiscal Year: 2006
    ..abstract_text> ..
  2. Heart failure, chronic kidney disease, and renin-angiotensin system inhibition
    Ali Ahmed; Fiscal Year: 2006
    ....
  3. Heart failure, chronic kidney disease, and renin-angiotensin system inhibition
    Ali Ahmed; Fiscal Year: 2007
    ....
  4. Heart failure, chronic kidney disease, and renin-angiotensin system inhibition
    Ali Ahmed; Fiscal Year: 2009
    ....
  5. Neurohormonal Blockade and Outcomes in Diastolic Heart Failure
    Ali Ahmed; Fiscal Year: 2009
    ..The proposed study will examine the effect of neurohormonal blockade in propensity matched OPTIMIZE-HF participants with diastolic heart failure. ..
  6. Heart failure, chronic kidney disease, and renin-angiotensin system inhibition
    Ali Ahmed; Fiscal Year: 2009
    ....
  7. Neurohormonal Blockade and Outcomes in Diastolic Heart Failure
    Ali Ahmed; Fiscal Year: 2010
    ..The proposed study will examine the effect of neurohormonal blockade in propensity matched OPTIMIZE-HF participants with diastolic heart failure. ..