Research Topics
| Pablo S AguilarSummaryAffiliation: University of California Country: USA Publications
| Collaborators |
Detail Information
Publications
The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast matingPablo S Aguilar
Howard Hughes Medical Institute, and Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94158, USA
Mol Biol Cell 18:547-56. 2007..Thus, our results suggest that Prm1 and Fig1 have a role in enhancing membrane fusion and maintaining its fidelity. Their absence results in frequent mating pair lysis, which is counteracted by Ca(2+)-dependent membrane repair...
Pil1 controls eisosome biogenesisKaren E Moreira
Howard Hughes Medical Institute, and Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94158, USA
Mol Biol Cell 20:809-18. 2009..Pil1 expression is regulated by the cell cycle, which synchronizes eisosome formation with plasma membrane growth. Our results establish a first framework of the molecular principles that define eisosome assembly and distribution...
Pkh-kinases control eisosome assembly and organizationTobias C Walther
Department of Biochemistry and Biophysics, Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, CA, USA
EMBO J 26:4946-55. 2007..Taken together with our previous results that link eisosomes to endocytosis, these observations suggest that Pkh-kinase signaling relayed to Pil1 may help regulate endocytic events to modulate the organization of the plasma membrane...
Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during matingPablo S Aguilar
Departments of Biochemistry and Biophysics, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA
Proc Natl Acad Sci U S A 107:4170-5. 2010..Thus, a two-atom change in the aliphatic moiety of ergosterol is sufficient to obstruct cell shape remodeling and cell fusion...
Eisosomes mark static sites of endocytosisTobias C Walther
Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of California at San Francisco, 600 16th Street, San Francisco, California 94143 2200, USA
Nature 439:998-1003. 2006..Loss of Pil1 leads to clustering of eisosome remnants and redirects endocytosis and endocytic effector proteins to these clusters...
