Affiliation: University of Maryland
- Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labourK Aguan
Department of Obstetrics, Gynecology and Reproductive Sciences, Bressler Research Building 11 048, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Mol Hum Reprod 6:1141-5. 2000..Our findings illustrate the advantage of a functional genomics approach over a single gene analysis in identifying a large number of novel and potentially important genes mediating uterine smooth muscle contractile activity...
- Chorion releases a factor that inhibits oxytocin-stimulated myometrial contractility in the pregnant guinea pigJ A Carvajal
Perinatal Research Laboratory, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Hum Reprod 16:638-43. 2001..It was concluded that the chorion releases a substance or substances that reduce oxytocin-stimulated myometrial contractility and may be involved in the maintenance of uterine quiescence during pregnancy...
- Natriuretic peptide-induced relaxation of myometrium from the pregnant guinea pig is not mediated by guanylate cyclase activationJ A Carvajal
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Bressler Research Building, 655 W. Baltimore St, Baltimore, MD 21201, USA
J Pharmacol Exp Ther 297:181-8. 2001..Our results suggest that natriuretic peptide-induced relaxation of pregnant myometrium is mediated via a novel mechanism...
- Effect of chronic hypoxemia on the regulation of nitric-oxide synthase in the fetal sheep brainK Aguan
Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore MD 21201, USA
Brain Res Dev Brain Res 111:271-7. 1998..On the other hand, downregulation of eNOS activity and expression may compromise the neuroprotective effect of eNOS and, therefore, further exacerbate brain injury...