Manish K Aghi

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Management of recurrent and refractory Cushing disease
    Manish K Aghi
    Neurological Surgery, The California Center for Pituitary Disorders, University of California, San Francisco UCSF, CA 94143 0112, USA
    Nat Clin Pract Endocrinol Metab 4:560-8. 2008
  2. pmc Hypoxia enhances the replication of oncolytic herpes simplex virus
    Manish K Aghi
    Department of Neurosurgery, University of California, San Francisco, California 94143 01112, USA
    Mol Ther 17:51-6. 2009
  3. doi request reprint Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation
    Manish K Aghi
    Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurgery 64:56-60; discussion 60. 2009
  4. doi request reprint Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
    Manish K Aghi
    Department of Neurological Surgery, University of California at San Francisco UCSF, San Francisco, CA 94143 0112, USA
    J Neurooncol 93:115-20. 2009
  5. doi request reprint Disseminated progression of glioblastoma after treatment with bevacizumab
    Orin Bloch
    Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, CA 94143 0112, USA
    Clin Neurol Neurosurg 115:1795-801. 2013
  6. doi request reprint Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurgery 70:361-70. 2012
  7. pmc Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94158, USA
    Clin Cancer Res 19:1773-83. 2013
  8. doi request reprint Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article
    Orin Bloch
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 117:1032-8. 2012
  9. doi request reprint Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
    Neurosurg Rev 36:349-59. 2013
  10. pmc Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
    Michael Delay
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    Clin Cancer Res 18:2930-42. 2012

Collaborators

Detail Information

Publications60

  1. doi request reprint Management of recurrent and refractory Cushing disease
    Manish K Aghi
    Neurological Surgery, The California Center for Pituitary Disorders, University of California, San Francisco UCSF, CA 94143 0112, USA
    Nat Clin Pract Endocrinol Metab 4:560-8. 2008
    ..Here, we review the treatment options and latest surgical, medical, and radiosurgical advances for patients who have persistent or recurrent Cushing disease after transsphenoidal surgery...
  2. pmc Hypoxia enhances the replication of oncolytic herpes simplex virus
    Manish K Aghi
    Department of Neurosurgery, University of California, San Francisco, California 94143 01112, USA
    Mol Ther 17:51-6. 2009
    ....
  3. doi request reprint Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation
    Manish K Aghi
    Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurgery 64:56-60; discussion 60. 2009
    ..We sought to define the long-term recurrence rate of AMs after GTR, along with factors predicting recurrence, including postoperative radiation...
  4. doi request reprint Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
    Manish K Aghi
    Department of Neurological Surgery, University of California at San Francisco UCSF, San Francisco, CA 94143 0112, USA
    J Neurooncol 93:115-20. 2009
    ....
  5. doi request reprint Disseminated progression of glioblastoma after treatment with bevacizumab
    Orin Bloch
    Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, CA 94143 0112, USA
    Clin Neurol Neurosurg 115:1795-801. 2013
    ..We have reviewed our institutional experience with bevacizumab for GBM to evaluate the prognostic factors and outcomes of patients with disseminated progression...
  6. doi request reprint Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurgery 70:361-70. 2012
    ..The management and prognosis of glioblastoma patients after Stupp protocol treatment and progression during bevacizumab (BV) treatment remain undefined...
  7. pmc Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94158, USA
    Clin Cancer Res 19:1773-83. 2013
    ..To identify mediators of glioblastoma antiangiogenic therapy resistance and target these mediators in xenografts...
  8. doi request reprint Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article
    Orin Bloch
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 117:1032-8. 2012
    ..In this study the authors investigate the impact of EOR at initial and repeat resection of GBM on overall survival...
  9. doi request reprint Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
    Neurosurg Rev 36:349-59. 2013
    ..Long-term follow-up will be needed to define recurrence rates of EEA as compared to transcranial approaches. Cautious use of EEA for the removal of smaller tuberculum sellae meningiomas after formal endoscopic training may be warranted...
  10. pmc Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
    Michael Delay
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    Clin Cancer Res 18:2930-42. 2012
    ..To identify mechanisms and mediators of resistance to antiangiogenic therapy in human glioblastoma...
  11. doi request reprint Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas
    Michael E Ivan
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    J Neurooncol 121:53-61. 2015
    ....
  12. doi request reprint Incidence of headache as a presenting complaint in over 1000 patients with sellar lesions and factors predicting postoperative improvement
    Arman Jahangiri
    Department of Neurosurgery and The California Center for Pituitary Disorders CCPD, University of California at San Francisco UCSF, San Francisco, USA
    Clin Neurol Neurosurg 132:16-20. 2015
    ..We sought to evaluate the incidence of headache as a presenting complaint in patients undergoing transsphenoidal surgery for various pathologies and to identify factors predicting postoperative improvement...
  13. pmc β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma
    W Shawn Carbonell
    Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Res 73:3145-54. 2013
    ..We concluded that β1 integrin upregulation in BRGs likely reflects an onset of hypoxia caused by antiangiogenic therapy, and that β1 inhibition is well tolerated in vivo as a tractable strategy to disrupt resistance to this therapy...
  14. doi request reprint Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations
    Arman Jahangiri
    Department of Neurosurgery and California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 119:1478-83. 2013
    ..The authors calculated the frequency of postoperative hyponatremia after 1045 consecutive operations and determined the efficacy of interventions correcting hyponatremia...
  15. doi request reprint Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations
    Arman Jahangiri
    Department of Neurosurgery and The California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 121:67-74. 2014
    ..The authors determined the morbidity associated with repeat versus initial transsphenoidal surgery after 1015 consecutive operations...
  16. doi request reprint Surgical outcomes in choroid plexus papillomas: an institutional experience
    Michael Safaee
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94117, USA
    J Neurooncol 113:117-25. 2013
    ..This modern experience at a tertiary care center performed exclusively during the MRI-era demonstrates that CPPs can be safely removed with minimal morbidity and good tumor control...
  17. doi request reprint Medical versus surgical management of prolactinomas
    Michael C Oh
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 23:669-78. 2012
    ..Rare prolactinomas that are unresponsive to either medical or surgical treatment modalities may be responsive to radiation therapy. This article reviews the recent advancements in the management of prolactinomas...
  18. pmc Tumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapy
    Yu Long Hu
    Department of Neurological Surgery and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143 0112, USA
    Cancer Res 72:4294-9. 2012
    ..Efforts to understand and modulate the autophagy pathway will be crucial to maximize the full therapeutic potential of cancer therapies that are currently hindered by tumor cell autophagy as a resistance mechanism...
  19. pmc Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging
    Ramon F Barajas
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158 2330, USA
    Neuro Oncol 14:942-54. 2012
    ..Image-guided tissue acquisition and assessment of residual tumor from treatment-naive GBM should be guided by DSC in CE regions and by DWI in NE regions...
  20. doi request reprint A critical evaluation of cystic features in primary glioblastoma as a prognostic factor for survival
    Gurvinder Kaur
    Department of Neurological Surgery, University of California, San Francisco, California, USA
    J Neurosurg 115:754-9. 2011
    ....
  21. doi request reprint Risk factors for postoperative cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery
    Michael E Ivan
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M7, San Francisco, CA 94143 0112, USA Center for Minimally Invasive Skull Base Surgery, University of California, San Francisco, CA, USA Electronic address
    J Clin Neurosci 22:48-54. 2015
    ..Risks associated with complex surgical resections when combining open and endoscopic approaches could be minimized by staging these procedures. ..
  22. doi request reprint A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas
    Arman Jahangiri
    Department of Neurosurgery and The California Center for Pituitary Disorders CCPD, University of California at San Francisco UCSF, San Francisco, California, USA
    Neurosurgery 73:8-17; discussion 17-8. 2013
    ..Silent corticotrophic adenomas (SCAs) stain adrenocorticotropic hormone (ACTH)+ without causing Cushing disease. SCAs are reportedly more aggressive, but information comes from small series...
  23. doi request reprint Use of thrombin-based hemostatic matrix during meningioma resection: a potential risk factor for perioperative thromboembolic events
    Michael Safaee
    Department of Neurological Surgery, University of California, San Francisco, USA
    Clin Neurol Neurosurg 119:116-20. 2014
    ..We performed a retrospective analysis to identify potential associations between hemostatic agent use and DVT/PE...
  24. doi request reprint Socioeconomic factors associated with pituitary apoplexy
    Arman Jahangiri
    Department of Neurological Surgery and California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 119:1432-6. 2013
    ..The association between pituitary apoplexy and socioeconomic factors that may limit access to health care has not been examined in prior studies...
  25. doi request reprint Outcomes and patterns of care in adult skull base chordomas from the Surveillance, Epidemiology, and End Results (SEER) database
    Pamela S Jones
    Department of Neurosurgery, Stephen L Harris Center for Chordoma Care, Massachusetts General Hospital, 55 Fruit Street, Yawkey 9E 9026, Boston, MA 02114, USA
    J Clin Neurosci 21:1490-6. 2014
    ..Findings of decreased survival in patients receiving radiation may be associated with selection. Studies examining surgical extent of resection data and radiation details are needed to determine the impact of radiotherapy...
  26. doi request reprint Clinical management of pituitary carcinomas
    Michael C Oh
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 23:595-606. 2012
    ..Here we review the clinical behavior and pathologic characteristics of pituitary carcinomas and the recent advances in potential therapies for this malignant disease...
  27. doi request reprint Skull base chordomas: clinical features, prognostic factors, and therapeutics
    Arman Jahangiri
    Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 24:79-88. 2013
    ..In this review, the histopathology and epidemiology, imaging characteristics, surgical approaches, adjuvant therapies, prognostic factors, and molecular biology of chordomas are described...
  28. doi request reprint Pseudoprogression and treatment effect
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA, USA
    Neurosurg Clin N Am 23:277-87, viii-ix. 2012
    ..Novel radiographic or nonradiographic biomarkers with sensitivity and specificity verified in large randomized clinical trials are needed to detect progression...
  29. doi request reprint A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass
    Jason S Cheng
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779 Moffitt Long Hospital, San Francisco, CA 94143 0112, USA Electronic address
    J Clin Neurosci 22:155-60. 2015
    ..These two factors correctly predicted 98.6% (69/70) of cases. Our model correctly classifies most patients with elevated serum prolactin and identifies those patients most amenable to surgical treatment...
  30. doi request reprint Factors predicting recurrence after resection of clival chordoma using variable surgical approaches and radiation modalities
    Arman Jahangiri
    Center for Minimally Invasive Skull Base Surgery MISB, University of California at San Francisco, San Francisco, California Department of Neurosurgery, Center for Minimally Invasive Skull Base Surgery MISB, University of California at San Francisco, San Francisco, California Department of Radiation Oncology, University of California at San Francisco, San Francisco, California Department of Neurosurgery, Northwestern University, Chicago, Illinois Skull Base and Cerebrovascular Laboratory, University of California at San Francisco, San Francisco, California Department of Otolaryngology, University of California at San Francisco, San Francisco, California
    Neurosurgery 76:179-85; discussion 185-6. 2015
    ..Clival chordomas frequently recur because of their location and invasiveness...
  31. doi request reprint Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts
    Arman Jahangiri
    California Center for Pituitary Disorders, Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0112, USA Center for Minimally Invasive Skull Base Surgery, University of California at San Francisco, San Francisco, CA, USA
    J Clin Neurosci 21:779-85. 2014
    ..05). Suprasellar RCC are neurosurgically challenging due to their proximity to the optic chiasm and infundibulum. Compared to microsurgery, endoscopy improves rate of complete removal and visual outcomes...
  32. doi request reprint Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease
    Matthew B Potts
    Department of Neurosurgery, University of California, San Francisco, 505 Parnassus Ave, M 779, San Francisco, CA, 94143 0112, USA
    J Neurooncol 116:593-600. 2014
    ..CVS, however, remains an important tool in the workup of Cushing's syndrome...
  33. pmc Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy
    Yu Long Hu
    Department of Neurosurgery, Diller Cancer Research Building, University of California at San Francisco UCSF, San Francisco, CA, USA
    Autophagy 8:979-81. 2012
    ..However, further work will clearly be needed to develop more potent and specific autophagy inhibitors and to better understand the regulators of autophagy in malignant cells...
  34. pmc VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
    Kan V Lu
    Department of Neurological Surgery, University of California, Helen Diller Family Cancer Research Center, San Francisco, CA 94143, USA
    Cancer Cell 22:21-35. 2012
    ..Inhibition of MET in GBM mouse models blocks mesenchymal transition and invasion provoked by VEGF ablation, resulting in substantial survival benefit...
  35. doi request reprint Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group
    Michael A Vogelbaum
    Brain Tumor and Neuro Oncology Center, Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurosurgery 70:234-43; discussion 243-4. 2012
    ..The RANO group identified knowledge gaps relating to the definitions of tumor response and progression after the use of surgical or surgically based treatments...
  36. doi request reprint Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes
    Matthew B Potts
    Department of Neurosurgery and California Center for Pituitary Disorders, University of California, San Francisco, California 94143 0112, USA
    Neurosurgery 69:1058-68; discussion 1068-7. 2011
    ..Rathke cleft cysts (RCCs), benign remnants of the Rathke pouch typically arising in the sella, sometimes have suprasellar extension. Purely suprasellar RCCs are rarely reported...
  37. ncbi request reprint Increased prevalence of obesity and obesity-related postoperative complications in male patients with meningiomas
    Manish K Aghi
    Neurosurgical Service, Massachusetts General Hospital, Department of Neurosurgery, Harvard Medical School, Boston, Massachusetts, USA
    Neurosurgery 61:754-60; discussion 760-1. 2007
    ..We hypothesized that because obesity affects male steroid hormone synthesis, male patients with meningiomas might exhibit a high obesity rate, which, in turn, might increase their frequency of postoperative complications...
  38. doi request reprint Reconstruction of dural defects of the endonasal skull base
    Michael E Sughrue
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94117, USA
    Neurosurg Clin N Am 21:637-41, vi. 2010
    ..In this review, the authors discuss known techniques for the repair of endonasal defects, and provide some insight based on their experience...
  39. doi request reprint Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco
    Corinna C Zygourakis
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Rm 779M, San Francisco, CA, 94143 0112, USA
    Pituitary 18:150-8. 2015
    ..To date, there are relatively few cases of pituicytomas and SCOs reported; and most of these are small case series...
  40. doi request reprint Gangliogliomas of the optic pathway
    John D Rolston
    Department of Neurological Surgery, University of California, 505 Parnassus Avenue, M779, San Francisco, CA 94143 0112, USA Electronic address
    J Clin Neurosci 21:2244-9. 2014
    ..Otherwise, when serviceable vision remains, subtotal resection with adjuvant radiation should be carried out when feasible. Despite treatment, the prognosis remains mixed, with roughly one-third of patients progressing. ..
  41. doi request reprint Gliosarcoma arising from an oligodendroglioma (oligosarcoma)
    Annie Hiniker
    Department of Pathology, University of California San Francisco, CA, USA
    Clin Neuropathol 32:165-70. 2013
    ..Here we present a case with detailed genetic evidence that suggests that mesenchymal metaplasia sarcomatous transformation is possible in classic oligodendrogliomas with 1p19q codeletions...
  42. doi request reprint Minimally invasive approaches to the anterior skull base
    Michael E Ivan
    Department of Neurological Surgery, University of California San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 24:19-37. 2013
    ....
  43. pmc Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma
    Yu Long Hu
    University of California at San Francisco Neurosurgery, San Francisco, California 94158, USA
    Cancer Res 72:1773-83. 2012
    ..One strong implication of our findings is that autophagy inhibitors may help prevent resistance to antiangiogenic therapy used in the clinic...
  44. doi request reprint Excess mortality for patients with residual disease following resection of pituitary adenomas
    Michael E Sughrue
    California Center for Pituitary Disorders, University of California, 400 Parnassus Avenue, Room A 808, San Francisco, CA 94143 0350, USA
    Pituitary 14:276-83. 2011
    ....
  45. doi request reprint Outcomes and patterns of care in adult skull base chondrosarcomas from the SEER database
    Pamela S Jones
    Department of Neurosurgery, Stephen E and Catherine Pappas Center for Neuro Oncology, Massachusetts General Hospital, 55 Fruit Street, Yawkey 9E 9026, Boston, MA 02114, USA
    J Clin Neurosci 21:1497-502. 2014
    ..Adjuvant radiation may also confer survival benefit. Optimal treatment strategy has yet to be defined in the literature...
  46. doi request reprint Approach to the postoperative patient with Cushing's disease
    Martin J Rutkowski
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M 779, San Francisco, CA, 94143, USA
    Pituitary 18:232-7. 2015
    ....
  47. doi request reprint Rathke's cleft cysts: review of natural history and surgical outcomes
    Seunggu J Han
    Department of Neurological Surgery, University of California at San Francisco UCSF, 505, Parnassus Avenue Room M779, San Francisco, CA, 94143 0112, USA
    J Neurooncol 117:197-203. 2014
    ....
  48. doi request reprint Tumors of the anterior skull base
    Michael E Ivan
    Department of Neurological Surgery, University of California, San Francisco, CA, USAand
    Expert Rev Neurother 14:425-38. 2014
    ..Surgical resection remains the mainstay in treatment of these tumors, particularly in the hands of experienced surgeons exercising proper patient and case selection. ..
  49. doi request reprint New advances that enable identification of glioblastoma recurrence
    Isaac Yang
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    Nat Rev Clin Oncol 6:648-57. 2009
    ..Further research will also be needed to develop improved algorithms that use these modalities, and to develop new modalities with even greater accuracy than those currently available...
  50. doi request reprint Dopamine agonist-resistant prolactinomas
    Michael C Oh
    California Center for Pituitary Disorders, Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 114:1369-79. 2011
    ....
  51. doi request reprint Infected Rathke cleft cysts: distinguishing factors and factors predicting recurrence
    Matthew C Tate
    Department of Neurosurgery, University of California at San Francisco, San Francisco, California, USA
    Neurosurgery 67:762-9; discussion 769. 2010
    ..Rathke cleft cysts (RCCs) are benign sellar lesions that are generally asymptomatic but sometimes warrant transsphenoidal drainage. Small case reports have described infected RCCs, but this phenomenon remains uncharacterized...
  52. doi request reprint Radiation treatment strategies for acromegaly
    Nathan C Rowland
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 29:E12. 2010
    ..As more efficient forms of pituitary radiation develop, acromegaly treatment options may continue to change with radiation therapies playing a more prominent role...
  53. doi request reprint Cushing's disease: current medical therapies and molecular insights guiding future therapies
    Darryl Lau
    Department of Neurological Surgery, University of California, San Francisco, California
    Neurosurg Focus 38:E11. 2015
    ..Ideally these agents should also reduce tumor size, which could potentially permit their eventual discontinuation. ..
  54. pmc Convection-enhanced delivery for the treatment of glioblastoma
    Michael A Vogelbaum
    Brain Tumor and Neuro Oncology Center and Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio M A V Department of Neurological Surgery, University of California, San Francisco, California M K A
    Neuro Oncol 17:ii3-ii8. 2015
    ..Further development of CED is ongoing, with novel catheter designs and imaging approaches that may allow CED to become a more effective therapeutic delivery technique. ..
  55. doi request reprint Risk factors for cerebrospinal leak after endoscopic skull base reconstruction with nasoseptal flap
    Calvin L Gruss
    School of Medicine, Vanderbilt University, Nashville, Tennessee, USA Department of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California, USA
    Otolaryngol Head Neck Surg 151:516-21. 2014
    ..We hypothesized that defect site impacts the rate of cerebrospinal fluid (CSF) leak following EES...
  56. doi request reprint Awards, lectures, and fellowships sponsored by the AANS/CNS Section on Tumors
    Darryl Lau
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue Room M779, San Francisco, CA, 94143 0112, USA
    J Neurooncol 119:583-91. 2014
    ..Specifically for the Preuss and Mahaley Awards, this article also examines the rates of publication among the award-winning abstracts and achievement of grant funding by awardees. ..
  57. doi request reprint Molecularly targeted therapies for recurrent glioblastoma: current and future targets
    Darryl Lau
    Department of Neurological Surgery, University of California, San Francisco, California
    Neurosurg Focus 37:E15. 2014
    ..This article aims to review the literature and highlight the mechanisms and efficacies of molecularly targeted therapies for recurrent glioblastoma...
  58. doi request reprint Headache and focal neurologic deficits in a 37-year-old woman
    Maranatha O Ayodele
    Department of Neurology, University of California, San Francisco
    JAMA Neurol 70:1445-9. 2013
    ..Serum and cerebrospinal fluid studies were unrevealing and a biopsy of the cystic lesions was performed. The clinical approach, differential diagnosis, and neuropathological findings are discussed. ..
  59. doi request reprint Biology of angiogenesis and invasion in glioma
    Matthew C Tate
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    Neurotherapeutics 6:447-57. 2009
    ..The findings provide a renewed hope for those endeavoring to improve treatment of patients with glioma by providing a novel set of rational targets for translational drug discovery...
  60. doi request reprint Impact of bevacizumab chemotherapy on craniotomy wound healing
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 114:1609-16. 2011
    ..Phase II trials reported 4%-6% impaired wound healing for bevacizumab initiated postoperatively. The effect of preoperative bevacizumab on subsequent craniotomy healing has not been addressed...