Manish K Aghi

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Management of recurrent and refractory Cushing disease
    Manish K Aghi
    Neurological Surgery, The California Center for Pituitary Disorders, University of California, San Francisco UCSF, CA 94143 0112, USA
    Nat Clin Pract Endocrinol Metab 4:560-8. 2008
  2. pmc Hypoxia enhances the replication of oncolytic herpes simplex virus
    Manish K Aghi
    Department of Neurosurgery, University of California, San Francisco, California 94143 01112, USA
    Mol Ther 17:51-6. 2009
  3. doi request reprint Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation
    Manish K Aghi
    Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurgery 64:56-60; discussion 60. 2009
  4. doi request reprint Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
    Manish K Aghi
    Department of Neurological Surgery, University of California at San Francisco UCSF, San Francisco, CA 94143 0112, USA
    J Neurooncol 93:115-20. 2009
  5. doi request reprint Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurgery 70:361-70. 2012
  6. pmc Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94158, USA
    Clin Cancer Res 19:1773-83. 2013
  7. doi request reprint Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article
    Orin Bloch
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 117:1032-8. 2012
  8. doi request reprint Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
    Neurosurg Rev 36:349-59. 2013
  9. pmc Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
    Michael Delay
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    Clin Cancer Res 18:2930-42. 2012
  10. doi request reprint β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma
    W Shawn Carbonell
    Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Res 73:3145-54. 2013

Collaborators

Detail Information

Publications39

  1. doi request reprint Management of recurrent and refractory Cushing disease
    Manish K Aghi
    Neurological Surgery, The California Center for Pituitary Disorders, University of California, San Francisco UCSF, CA 94143 0112, USA
    Nat Clin Pract Endocrinol Metab 4:560-8. 2008
    ..Here, we review the treatment options and latest surgical, medical, and radiosurgical advances for patients who have persistent or recurrent Cushing disease after transsphenoidal surgery...
  2. pmc Hypoxia enhances the replication of oncolytic herpes simplex virus
    Manish K Aghi
    Department of Neurosurgery, University of California, San Francisco, California 94143 01112, USA
    Mol Ther 17:51-6. 2009
    ....
  3. doi request reprint Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation
    Manish K Aghi
    Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurgery 64:56-60; discussion 60. 2009
    ..We sought to define the long-term recurrence rate of AMs after GTR, along with factors predicting recurrence, including postoperative radiation...
  4. doi request reprint Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
    Manish K Aghi
    Department of Neurological Surgery, University of California at San Francisco UCSF, San Francisco, CA 94143 0112, USA
    J Neurooncol 93:115-20. 2009
    ....
  5. doi request reprint Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurgery 70:361-70. 2012
    ..The management and prognosis of glioblastoma patients after Stupp protocol treatment and progression during bevacizumab (BV) treatment remain undefined...
  6. pmc Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94158, USA
    Clin Cancer Res 19:1773-83. 2013
    ..To identify mediators of glioblastoma antiangiogenic therapy resistance and target these mediators in xenografts...
  7. doi request reprint Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article
    Orin Bloch
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 117:1032-8. 2012
    ..In this study the authors investigate the impact of EOR at initial and repeat resection of GBM on overall survival...
  8. doi request reprint Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
    Neurosurg Rev 36:349-59. 2013
    ..Long-term follow-up will be needed to define recurrence rates of EEA as compared to transcranial approaches. Cautious use of EEA for the removal of smaller tuberculum sellae meningiomas after formal endoscopic training may be warranted...
  9. pmc Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
    Michael Delay
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    Clin Cancer Res 18:2930-42. 2012
    ..To identify mechanisms and mediators of resistance to antiangiogenic therapy in human glioblastoma...
  10. doi request reprint β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma
    W Shawn Carbonell
    Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Res 73:3145-54. 2013
    ..We concluded that β1 integrin upregulation in BRGs likely reflects an onset of hypoxia caused by antiangiogenic therapy, and that β1 inhibition is well tolerated in vivo as a tractable strategy to disrupt resistance to this therapy...
  11. doi request reprint Surgical outcomes in choroid plexus papillomas: an institutional experience
    Michael Safaee
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94117, USA
    J Neurooncol 113:117-25. 2013
    ..This modern experience at a tertiary care center performed exclusively during the MRI-era demonstrates that CPPs can be safely removed with minimal morbidity and good tumor control...
  12. doi request reprint Disseminated progression of glioblastoma after treatment with bevacizumab
    Orin Bloch
    Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, CA 94143 0112, USA
    Clin Neurol Neurosurg 115:1795-801. 2013
    ..We have reviewed our institutional experience with bevacizumab for GBM to evaluate the prognostic factors and outcomes of patients with disseminated progression...
  13. doi request reprint Medical versus surgical management of prolactinomas
    Michael C Oh
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 23:669-78. 2012
    ..Rare prolactinomas that are unresponsive to either medical or surgical treatment modalities may be responsive to radiation therapy. This article reviews the recent advancements in the management of prolactinomas...
  14. pmc Tumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapy
    Yu Long Hu
    Department of Neurological Surgery and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143 0112, USA
    Cancer Res 72:4294-9. 2012
    ..Efforts to understand and modulate the autophagy pathway will be crucial to maximize the full therapeutic potential of cancer therapies that are currently hindered by tumor cell autophagy as a resistance mechanism...
  15. pmc Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging
    Ramon F Barajas
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158 2330, USA
    Neuro Oncol 14:942-54. 2012
    ..Image-guided tissue acquisition and assessment of residual tumor from treatment-naive GBM should be guided by DSC in CE regions and by DWI in NE regions...
  16. doi request reprint A critical evaluation of cystic features in primary glioblastoma as a prognostic factor for survival
    Gurvinder Kaur
    Department of Neurological Surgery, University of California, San Francisco, California, USA
    J Neurosurg 115:754-9. 2011
    ....
  17. doi request reprint Socioeconomic factors associated with pituitary apoplexy
    Arman Jahangiri
    Department of Neurological Surgery and California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 119:1432-6. 2013
    ..The association between pituitary apoplexy and socioeconomic factors that may limit access to health care has not been examined in prior studies...
  18. doi request reprint Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations
    Arman Jahangiri
    Department of Neurosurgery and California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 119:1478-83. 2013
    ..The authors calculated the frequency of postoperative hyponatremia after 1045 consecutive operations and determined the efficacy of interventions correcting hyponatremia...
  19. doi request reprint Skull base chordomas: clinical features, prognostic factors, and therapeutics
    Arman Jahangiri
    Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 24:79-88. 2013
    ..In this review, the histopathology and epidemiology, imaging characteristics, surgical approaches, adjuvant therapies, prognostic factors, and molecular biology of chordomas are described...
  20. doi request reprint Clinical management of pituitary carcinomas
    Michael C Oh
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 23:595-606. 2012
    ..Here we review the clinical behavior and pathologic characteristics of pituitary carcinomas and the recent advances in potential therapies for this malignant disease...
  21. doi request reprint Pseudoprogression and treatment effect
    Arman Jahangiri
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, Room M779, San Francisco, CA, USA
    Neurosurg Clin N Am 23:277-87, viii-ix. 2012
    ..Novel radiographic or nonradiographic biomarkers with sensitivity and specificity verified in large randomized clinical trials are needed to detect progression...
  22. doi request reprint A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas
    Arman Jahangiri
    Department of Neurosurgery and The California Center for Pituitary Disorders CCPD, University of California at San Francisco UCSF, San Francisco, California, USA
    Neurosurgery 73:8-17; discussion 17-8. 2013
    ..Silent corticotrophic adenomas (SCAs) stain adrenocorticotropic hormone (ACTH)+ without causing Cushing disease. SCAs are reportedly more aggressive, but information comes from small series...
  23. pmc Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy
    Yu Long Hu
    Department of Neurosurgery, Diller Cancer Research Building, University of California at San Francisco UCSF, San Francisco, CA, USA
    Autophagy 8:979-81. 2012
    ..However, further work will clearly be needed to develop more potent and specific autophagy inhibitors and to better understand the regulators of autophagy in malignant cells...
  24. doi request reprint VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
    Kan V Lu
    Department of Neurological Surgery, University of California, Helen Diller Family Cancer Research Center, San Francisco, CA 94143, USA
    Cancer Cell 22:21-35. 2012
    ..Inhibition of MET in GBM mouse models blocks mesenchymal transition and invasion provoked by VEGF ablation, resulting in substantial survival benefit...
  25. doi request reprint Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes
    Matthew B Potts
    Department of Neurosurgery and California Center for Pituitary Disorders, University of California, San Francisco, California 94143 0112, USA
    Neurosurgery 69:1058-68; discussion 1068-7. 2011
    ..Rathke cleft cysts (RCCs), benign remnants of the Rathke pouch typically arising in the sella, sometimes have suprasellar extension. Purely suprasellar RCCs are rarely reported...
  26. doi request reprint Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group
    Michael A Vogelbaum
    Brain Tumor and Neuro Oncology Center, Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurosurgery 70:234-43; discussion 243-4. 2012
    ..The RANO group identified knowledge gaps relating to the definitions of tumor response and progression after the use of surgical or surgically based treatments...
  27. ncbi request reprint Increased prevalence of obesity and obesity-related postoperative complications in male patients with meningiomas
    Manish K Aghi
    Neurosurgical Service, Massachusetts General Hospital, Department of Neurosurgery, Harvard Medical School, Boston, Massachusetts, USA
    Neurosurgery 61:754-60; discussion 760-1. 2007
    ..We hypothesized that because obesity affects male steroid hormone synthesis, male patients with meningiomas might exhibit a high obesity rate, which, in turn, might increase their frequency of postoperative complications...
  28. doi request reprint Reconstruction of dural defects of the endonasal skull base
    Michael E Sughrue
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, CA 94117, USA
    Neurosurg Clin N Am 21:637-41, vi. 2010
    ..In this review, the authors discuss known techniques for the repair of endonasal defects, and provide some insight based on their experience...
  29. doi request reprint Minimally invasive approaches to the anterior skull base
    Michael E Ivan
    Department of Neurological Surgery, University of California San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 24:19-37. 2013
    ....
  30. doi request reprint Gliosarcoma arising from an oligodendroglioma (oligosarcoma)
    Annie Hiniker
    Department of Pathology, University of California San Francisco, CA, USA
    Clin Neuropathol 32:165-70. 2013
    ..Here we present a case with detailed genetic evidence that suggests that mesenchymal metaplasia sarcomatous transformation is possible in classic oligodendrogliomas with 1p19q codeletions...
  31. pmc Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma
    Yu Long Hu
    University of California at San Francisco Neurosurgery, San Francisco, California 94158, USA
    Cancer Res 72:1773-83. 2012
    ..One strong implication of our findings is that autophagy inhibitors may help prevent resistance to antiangiogenic therapy used in the clinic...
  32. doi request reprint Excess mortality for patients with residual disease following resection of pituitary adenomas
    Michael E Sughrue
    California Center for Pituitary Disorders, University of California, 400 Parnassus Avenue, Room A 808, San Francisco, CA 94143 0350, USA
    Pituitary 14:276-83. 2011
    ....
  33. doi request reprint Radiation treatment strategies for acromegaly
    Nathan C Rowland
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 29:E12. 2010
    ..As more efficient forms of pituitary radiation develop, acromegaly treatment options may continue to change with radiation therapies playing a more prominent role...
  34. doi request reprint New advances that enable identification of glioblastoma recurrence
    Isaac Yang
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    Nat Rev Clin Oncol 6:648-57. 2009
    ..Further research will also be needed to develop improved algorithms that use these modalities, and to develop new modalities with even greater accuracy than those currently available...
  35. doi request reprint Dopamine agonist-resistant prolactinomas
    Michael C Oh
    California Center for Pituitary Disorders, Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 114:1369-79. 2011
    ....
  36. doi request reprint Infected Rathke cleft cysts: distinguishing factors and factors predicting recurrence
    Matthew C Tate
    Department of Neurosurgery, University of California at San Francisco, San Francisco, California, USA
    Neurosurgery 67:762-9; discussion 769. 2010
    ..Rathke cleft cysts (RCCs) are benign sellar lesions that are generally asymptomatic but sometimes warrant transsphenoidal drainage. Small case reports have described infected RCCs, but this phenomenon remains uncharacterized...
  37. doi request reprint Headache and focal neurologic deficits in a 37-year-old woman
    Maranatha O Ayodele
    Department of Neurology, University of California, San Francisco
    JAMA Neurol 70:1445-9. 2013
    ..Serum and cerebrospinal fluid studies were unrevealing and a biopsy of the cystic lesions was performed. The clinical approach, differential diagnosis, and neuropathological findings are discussed. ..
  38. doi request reprint Biology of angiogenesis and invasion in glioma
    Matthew C Tate
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    Neurotherapeutics 6:447-57. 2009
    ..The findings provide a renewed hope for those endeavoring to improve treatment of patients with glioma by providing a novel set of rational targets for translational drug discovery...
  39. doi request reprint Impact of bevacizumab chemotherapy on craniotomy wound healing
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 114:1609-16. 2011
    ..Phase II trials reported 4%-6% impaired wound healing for bevacizumab initiated postoperatively. The effect of preoperative bevacizumab on subsequent craniotomy healing has not been addressed...