Affiliation: University of Missouri
- Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specificallyCansu Agca
University of Missouri College of Veterinary Medicine, Department of Veterinary Pathobiology Columbia, MO 65211, USA
BMC Neurosci 9:28. 2008..Some instances of FAD have been linked to mutations in the beta-amyloid protein precursor (APP). Although there are numerous mouse AD models available, few rat AD models, which have several advantages over mice, have been generated...
- Development of a novel transgenic rat overexpressing the P2Y(2) nucleotide receptor using a lentiviral vectorCansu Agca
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vasc Res 46:447-58. 2009..This transgenic rat model of P2Y(2)R overexpression may prove useful for linking P2Y(2)R upregulation with chronic inflammatory diseases, neurodegenerative diseases and Sjogren's syndrome...
- Changes in rat spermatozoa function after cooling, cryopreservation and centrifugation processesSuhee Kim
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri Columbia, Columbia, MO 65211, USA
Cryobiology 65:215-23. 2012..Thus, protection from ROS damage and minimizing centrifugation should be considered during cryopreservation and post-thaw use of cryopreserved epididymal rat spermatozoa...