Research Topics
| Nzhde AgazaryanSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Image-guided radiosurgery for spinal tumors: methods, accuracy and patient intrafraction motionNzhde Agazaryan
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Phys Med Biol 53:1715-27. 2008..5 degrees were observed. The small relative rotational movements observed do not, alone, justify patient monitoring using the image-guidance system during the treatments of generally small radiosurgical targets...
A methodology for verification of radiotherapy dose calculationNzhde Agazaryan
Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6951, USA
J Neurosurg 101:356-61. 2004..Dosimetric accuracy of clinically active intensity-modulated radiotherapy (IMRT) and intensity-modulated radiosurgery (IMRS) programs was assessed using this methodology...
The effects of tumor motion on planning and delivery of respiratory-gated IMRTGeoffrey D Hugo
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
Med Phys 30:1052-66. 2003..The utilization of gating for IMRT treatment, including imaging, planning, and delivery, significantly reduces the errors introduced by object motion...
Segmental and dynamic intensity-modulated radiotherapy delivery techniques for micro-multileaf collimatorNzhde Agazaryan
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 6951, USA
Med Phys 30:1758-67. 2003....
Dedicated linear accelerator radiosurgery for trigeminal neuralgia: a single-center experience in 179 patients with varied dose prescriptions and treatment plansZachary A Smith
Department of Neurosurgery, UCLA Medical Center, West Los Angeles Veteran s Administration Hospital, Los Angeles, CA, USA
Int J Radiat Oncol Biol Phys 81:225-31. 2011..Although the use of gamma knife continues to be established, few large series exist using D-LINAC. The authors describe their results, comparing the effects of varied target and dose regimens...
Challenges in linear accelerator radiotherapy for chordomas and chondrosarcomas of the skull base: focus on complicationsJason S Hauptman
Division of Stereotactic and Functional Neurosurgery, Department of Neurosurgery, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095 7039, USA
Int J Radiat Oncol Biol Phys 83:542-51. 2012..Currently, consensus therapy includes surgical resection and adjuvant radiotherapy. Radiation delivery is typically limited by the proximity of these tumors to critical skull base structures...
Stereotactic radiation treatment for recurrent nonbenign meningiomasCarlos A Mattozo
Division of Neurosurgery, University of California at Los Angeles School of Medicine, Los Angeles, California 90095, USA
J Neurosurg 106:846-54. 2007....
Initial clinical experience with image-guided linear accelerator-based spinal radiosurgery for treatment of benign nerve sheath tumorsMichael T Selch
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 6951, USA
Surg Neurol 72:668-74; discussion 674-5. 2009..Stereotactic radiosurgery has proven a safe and effective treatment of cranial nerve sheath tumors. A similar approach should be successful for histologically identical spinal nerve sheath tumors...
Stereotactic radiotherapy for the treatment of acoustic neuromasMichael T Selch
Department of Radiation Oncology and Division of Neurosurgery, David Geffen School of Medicine, University of California, 90045 6951, USA
J Neurosurg 101:362-72. 2004..The authors sought to assess the safety and efficacy of stereotactic radiotherapy when using a linear accelerator equipped with a micromultileaf collimator for the treatment of patients with acoustic neuromas...
A feasibility study of 18F-fluorodeoxyglucose positron emission tomography targeting and simultaneous integrated boost for intensity-modulated radiosurgery and radiotherapyTimothy D Solberg
Department of Radiation Oncology, David Geffen School of Medicine, University of California, 90095 6951, USA
J Neurosurg 101:381-9. 2004....
Brainstem and trigeminal nerve changes after radiosurgery for trigeminal painAlessandra Gorgulho
Division of Neurosurgery, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA 90095, USA
Surg Neurol 66:127-35; discussion 135. 2006..Pons volume irradiated did not predict enhancement occurrence. Radiation delivery to the brainstem-REZ interface seems to improve pain outcome, although more paresthesias should be expected...
Image-guided linear accelerator-based spinal radiosurgery for hemangioblastomaMichael T Selch
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Surg Neurol Int 3:73. 2012..To retrospectively review the efficacy and safety of image-guided linear accelerator-based radiosurgery for spinal hemangioblastomas...
Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapyAntonio A F De Salles
Division of Neurosurgery and Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California, USA
J Neurosurg 101:435-40. 2004..Spinal radiosurgery was implemented to improve quality of life (QOL) in patients with malignancies. It may also be applicable to the treatment of benign lesions...
Patient specific quality assurance for the delivery of intensity modulated radiotherapyNzhde Agazaryan
Department of Radiation Oncology, UCLA School of Medicine, 200 UCLA Medical Plaza, Suite B265, Los Angeles, California 90095 6951, USA
J Appl Clin Med Phys 4:40-50. 2003..Absolute dosimetry for each composite plan is performed using an ionization chamber. To date, excellent agreement between measurements and calculations has been observed...
A seed specific dose kernel method for low-energy brachytherapy dosimetryJohn J DeMarco
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
J Appl Clin Med Phys 4:66-74. 2003..Good agreement is achieved for a representative pre- and post-plan comparison versus a commercial implementation of the TG-43 brachytherapy dosimetry protocol...
An evaluation of gating window size, delivery method, and composite field dosimetry of respiratory-gated IMRTGeoffrey D Hugo
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
Med Phys 29:2517-25. 2002..For multiple field IMRT delivery, the largest errors were generated in regions where high field modulation was present parallel to the axis of motion. Gating was found to reduce these large errors to clinically acceptable levels...
Treatment of giant cerebral arteriovenous malformation: hypofractionated stereotactic radiation as the first stageFuren Xiao
Division of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA
Neurosurgery 67:1253-9; discussion 1259. 2010..Treatment of giant cerebral arteriovenous malformations (AVMs) remains a challenge...
Time-course of effects of external beam radiation on [18F]FDG uptake in healthy tissue and bone marrowAdam L Kesner
Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 6942, USA
J Appl Clin Med Phys 9:2747. 2008....
Intraoperative ultrasonography-guided positioning of iodine 125 plaque brachytherapy in the treatment of choroidal melanomaMelinda Y Chang
Department of Ophthalmology, University of California, Los Angeles, CA, USA
Ophthalmology 119:1073-7. 2012..To report intraoperative ultrasonography-guided positioning of iodine 125 (I(125)) plaques for brachytherapy of choroidal melanoma as a quality improvement measure...
Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant gliomaPatrick Evers
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
BMC Cancer 10:384. 2010..This suggests that the NSC niches in the brain may harbor cancer stem cells (CSCs), Thus providing novel therapy targets. We hypothesize that higher radiation doses to these NSC niches improve patient survival by eradicating CSCs...
Radiation enhances regulatory T cell representationEvelyn L Kachikwu
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
Int J Radiat Oncol Biol Phys 81:1128-35. 2011..This study was undertaken to evaluate the impact of radiation therapy (RT) on immunosuppressive T regulatory (Treg) cells...
Degeneracy, frequency response and filtering in IMRT optimizationJorge Llacer
EC Engineering Consultants LLC, 130 Forest Hill Drive, Los Gatos, CA 95032, USA
Phys Med Biol 49:2853-80. 2004..Stopping points for the studied algorithms are discussed and the deterioration of DVH characteristics with filtering is shown to be partially recoverable by the use of space-variant filtering techniques...
