Research Topics
| F R AdlerSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Models of contrasting strategies of rhinovirus immune manipulationFrederick R Adler
Department of Mathematics, 155 South 1400 East, University of Utah, Salt Lake City, UT 84112, United States Department of Biology, 257 South 1400 East, University of Utah, Salt Lake City, UT 84112, United States Electronic address
J Theor Biol 327:1-10. 2013..This model of infection by a highly adapted and low virulence virus provides a starting point for understanding the development of asthma and other pathologies...- The role of heterogeneity in the persistence and prevalence of Sin Nombre virus in deer miceF R Adler
Department of Biology and Department of Mathematics, University of Utah, Salt Lake City, Utah 84112, USA
Am Nat 172:855-67. 2008..This buffering effect is not significantly stronger in a fluctuating population, indicating that these forms of heterogeneity might not be the key for disease persistence through host population bottlenecks... 
How host population dynamics translate into time-lagged prevalence: an investigation of Sin Nombre virus in deer miceFrederick R Adler
Department of Mathematics and Department of Biology, 155 South 1400 East, University of Utah, Salt Lake City, UT 84112, USA
Bull Math Biol 70:236-52. 2008..Population size variation due to variation in birth rates rather than death rates also increases the lag. Predicting future human outbreaks of hantavirus pulmonary syndrome may require taking these effects into account...- Commentary on Calcagno et al. (2006): Coexistence in a metacommunity: the competition-colonization trade-off is not deadFrederick R Adler
Department of Mathematics and Department of Biology, University of Utah, Salt Lake City, UT 84112, USA
Ecol Lett 9:907-9; discussion 909-911. 2006 - How to make a biological switchJ L Cherry
Department of Biology, University of Utah, Salt Lake City, UT, 84112, USA
J Theor Biol 203:117-33. 2000..However, functions describing positive cooperativity of binding, non-additive effects of multiple operator sites, or depletion of free repressor can lead to working switches... 
Predictive 5-year survivorship model of cystic fibrosisT G Liou
Department of Internal Medicine, Health Sciences Center, University of Utah, Salt Lake City 84132, USA
Am J Epidemiol 153:345-52. 2001..The model provides insights into the complex nature of cystic fibrosis and supplies a rigorous tool for clinical practice and research...- Survival effect of lung transplantation among patients with cystic fibrosisT G Liou
Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, 50 N Medical Dr, Salt Lake City, UT 84132, USA
JAMA 286:2683-9. 2001..Patients with cystic fibrosis (CF) are the second largest group of lung transplant recipients in the United States. The survival effect of transplantation on a general CF population has not previously been measured... - Genetic and phylogenetic consequences of island biogeographyK P Johnson
Department of Biology, University of Utah, Salt Lake City 84112 0840, USA
Evolution 54:387-96. 2000..Likewise, populations on distant islands should be more divergent than those on close islands. Published observations of a larger proportion of endemic species on large and distant islands support these predictions... - Testing the 'rare pit' hypothesis for xylem cavitation resistance in three species of AcerMairgareth A Christman
Department of Biology, University of Utah, Salt Lake City, UT 84025, USA
New Phytol 182:664-74. 2009..Adjustments in membrane properties and extent of pitting per vessel apparently combine to influence cavitation resistance across species... - An accurate two-phase approximate solution to an acute viral infection modelAmber M Smith
Department of Mathematics, University of Utah, Salt Lake City, UT 84112, USA
J Math Biol 60:711-26. 2010..We discuss applications of this analysis in antiviral treatments and in investigating host and virus heterogeneities... - Use of lung transplantation survival models to refine patient selection in cystic fibrosisTheodore G Liou
Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA
Am J Respir Crit Care Med 171:1053-9. 2005..Adult patients with low 5-year predicted survival without B. cepacia infection should receive priority for lung transplantation... - Gene genealogies strongly distorted by weakly interfering mutations in constant environmentsJon Seger
Ocean Alliance Whale Conservation Institute, Lincoln, Massachusetts 01773, USA
Genetics 184:529-45. 2010..A genealogical perspective on Hill-Robertson interference leads directly to a generalized background-selection model in which the effective population size is progressively reduced going back in time from the present... - Water transport in plants obeys Murray's lawKatherine A McCulloh
Department of Biology, University of Utah, Salt Lake City, Utah 84112, USA
Nature 421:939-42. 2003..Our measurements of plant xylem indicate that these conduits conform to the Murray's law optimum as long as they do not function additionally as supports for the plant body... - Selection of patients with cystic fibrosis for lung transplantationTheodore G Liou
Intermountain Cystic Fibrosis Center, Department of Internal Medicine, Division of Respiratory Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City 84132, USA
Curr Opin Pulm Med 8:535-41. 2002..However, judicious use of the survival model to select patients for transplantation is likely to improve survival outcomes... - Lung transplantation and survival in children with cystic fibrosisTheodore G Liou
Department of Internal Medicine, University of Utah, Salt Lake City, USA
N Engl J Med 357:2143-52. 2007..The effects of lung transplantation on the survival and quality of life in children with cystic fibrosis are uncertain... - Lung transplantation for cystic fibrosisFrederick R Adler
Department of Mathematics, University of Utah, Salt Lake City, Utah 84112, USA
Proc Am Thorac Soc 6:619-33. 2009..Finally, the conference members carefully considered how efforts to improve outcomes for lung transplantation for CF lung disease might best be studied. This Roundtable seeks to communicate the substance of our discussions... - Use of strain typing data to estimate bacterial transmission rates in healthcare settingsBrian R Jackson
Department of Medical Informatics, University of Utah, Salt Lake City, Utah, USA
Infect Control Hosp Epidemiol 26:638-45. 2005..A modest level of surveillance sampling substantially improves the estimation accuracy... - Quasi-species evolution in subdivided populations favours maximally deleterious mutationsBrendan D O'Fallon
Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
Proc Biol Sci 274:3159-64. 2007..Our results indicate that RNA viruses that produce acute infections initiated by a small number of virions are expected to evolve fragile genetic architectures when compared with other RNA viruses... - Stochasticity, complex spatial structure, and the feasibility of the shifting balance theoryBrendan O'Fallon
Department of Biology, University of Utah, Salt Lake City 84112, USA
Evolution 60:448-59. 2006..These results suggest that the shifting balance process may operate under less restrictive conditions than those found with a simple spatial arrangement of demes... - Major histocompatibility complex controls the trajectory but not host-specific adaptation during virulence evolution of the pathogenic fungus Cryptococcus neoformansErin E McClelland
Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
Proc Biol Sci 271:1557-64. 2004.... - Optimization, conflict, and nonoverlapping foraging ranges in antsFrederick R Adler
Department of Mathematics and Department of Biology, University of Utah, Salt Lake City, Utah, 84112, USA
Am Nat 162:529-43. 2003..Deviations between model predictions and data indicate that colonies might allocate a larger than optimal number of foragers to areas near boundaries between foraging ranges... - Correction: Lung transplantation and survival in children with cystic fibrosisTheodore G Liou
N Engl J Med 359:536. 2008 - Priorities for lung transplantation among patients with cystic fibrosisTheodore G Liou
JAMA 287:1523-4; author reply 1524-5. 2002 - Testing lung function decline to time lung transplantationTheodore G Liou
Chest 128:472-3; author reply 473-4. 2005 - Islands, equilibria, and speciationJoshua L Cherry
Department of Organismic, and Evolutionary Biology, Harvard University, Cambridge, MA 02140, USA
Science 296:975. 2002