Research Topics
| Caleb M AdlerSummaryAffiliation: University of Cincinnati Country: USA Publications
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Detail Information
Publications
Brain network dysfunction in bipolar disorderCaleb M Adler
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
CNS Spectr 11:312-20; quiz 323-4. 2006..As neuroimaging techniques continue to improve, the underlying neural basis of bipolar disorder will be clarified...
A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood statesMichael A Cerullo
Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
Bipolar Disord 14:175-84. 2012..To further understand the role of the amygdala in the generation of mood symptoms, we used functional magnetic resonance imaging (fMRI) to examine a group of patients with bipolar I disorder longitudinally...
The functional neuroanatomy of bipolar disorderMichael A Cerullo
Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Int Rev Psychiatry 21:314-22. 2009..Additionally, most studies were confounded by patients taking psychotropic medications. Nonetheless, from this work an anterior limbic over-activation model of bipolar disorder is emerging...- Characterizing impulsivity in maniaStephen M Strakowski
Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
Bipolar Disord 11:41-51. 2009.... - Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for maniaStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
Arch Gen Psychiatry 64:57-64. 2007..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied... - Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathwayStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559 USA
Biol Psychiatry 69:381-8. 2011..We used functional magnetic resonance imaging (fMRI) to study manic bipolar subjects as they performed a cognitive task designed to examine the ventrolateral prefrontal emotional arousal network... - Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorderDavid E Fleck
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
J Affect Disord 133:333-9. 2011..The aim of this study was to examine whether the neural correlates of motor impulsivity are distinct in patients with mixed mania... - Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy studyJeffrey R Strawn
University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
J Am Acad Child Adolesc Psychiatry 51:642-51. 2012.... - The neurophysiology of childhood and adolescent bipolar disorderMelissa P DelBello
Division of Bipolar Disorder Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
CNS Spectr 11:298-311. 2006.... - Impulsivity across the course of bipolar disorderStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
Bipolar Disord 12:285-97. 2010..To determine whether abnormalities of impulse control persist across the course of bipolar disorder, thereby representing potential state markers and endophenotypes... - Neuroanatomical characterization of child offspring of bipolar parentsManpreet K Singh
Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, OH 45267 0559, USA
J Am Acad Child Adolesc Psychiatry 47:526-31. 2008..We hypothesized that at-risk (AR) children would exhibit abnormalities in brain regions that are involved in mood regulation... - Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention taskCaleb M Adler
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Bipolar Disord 7:577-88. 2005..In this study we utilized functional magnetic resonance imaging (fMRI) to compare activation patterns during performance of a simple attention task between bipolar adolescents with and without ADHD... - Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disordersMichael A Cerullo
Division of Bipolar Disorders Research, Department of Psychiatry, and The Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Early Interv Psychiatry 3:189-97. 2009..In contrast, we hypothesized that bipolar subjects would show altered brain activation in regions responsible for emotionally homeostasis, including the striatum and amygdala... - Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference taskStephen M Strakowski
Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
Am J Psychiatry 162:1697-705. 2005..Cognitive probes, coupled with neuroimaging, provide an approach toward clarifying the neurophysiology of bipolar disorder... - Lithium treatment effects on Myo-inositol in adolescents with bipolar depressionNick C Patel
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0004, USA
Biol Psychiatry 60:998-1004. 2006..This study used proton magnetic resonance spectroscopy (1H MRS) to identify the in vivo effects of lithium on myo-inositol (mI) concentrations in adolescent bipolar depression... - The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s)Drew H Barzman
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
J Child Adolesc Psychopharmacol 16:665-70. 2006..The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders... - Voxel-based study of structural changes in first-episode patients with bipolar disorderCaleb M Adler
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
Biol Psychiatry 61:776-81. 2007..In this study, we used VBM to explore structural brain changes in first-episode bipolar patients... - Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episodeMelissa P DelBello
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 164:582-90. 2007..The aim of this study was to examine the 12-month outcome of bipolar adolescents following an initial hospitalization for a manic or mixed episode... - Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition taskStephen M Strakowski
Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Early Interv Psychiatry 2:225-33. 2008..Impulsivity is common in bipolar disorder, especially during mania. Understanding the functional neuroanatomy of response inhibition, one component of impulsivity, might clarify the neural substrate of bipolar disorder... - Neuroanatomic comparison of bipolar adolescents with and without cannabis use disordersKelly Jarvis
University of Cincinnati, Division of Bipolar Disorders Research, Department of Psychiatry, Cincinnati, OH 45267 0559, USA
J Child Adolesc Psychopharmacol 18:557-63. 2008..In this pilot study, we compared brain morphometry between bipolar adolescents with co-occurring cannabis use disorders (CUD) and bipolar adolescents without any substance use disorder... - A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorderMelissa P DelBello
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 260 Stetson Street, Suite 3200, ML 559, Cincinnati, OH 45219, USA
Bipolar Disord 11:483-93. 2009..To conduct a pilot study comparing the effects of quetiapine and placebo for the treatment of depressive episodes in adolescents with bipolar I disorder... - Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorderCaleb M Adler
Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Affect Disord 100:S15-22. 2007..To review the safety/tolerability of quetiapine in four placebo-controlled studies in patients with bipolar I disorder experiencing acute mania... - Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging studyCaleb M Adler
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 163:322-4. 2006..In this study the authors utilized diffusion tensor imaging to study white matter tracts of adolescents in their first episode of mania to address whether abnormalities are present in early bipolar disorder... - The functional neuroanatomy of bipolar disorder: a consensus modelStephen M Strakowski
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 14:313-25. 2012.... - Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness ScaleJayasree J Nandagopal
Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
J Child Adolesc Psychopharmacol 21:465-8. 2011.... - A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorderStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, OH 45267 0583, USA
Neuropsychopharmacology 29:1734-40. 2004..Since the differences occurred in euthymia, they may represent trait, rather than state, abnormalities of brain function in bipolar disorder... - Meta-analysis of amygdala volumes in children and adolescents with bipolar disorderJonathan C Pfeifer
Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
J Am Acad Child Adolesc Psychiatry 47:1289-98. 2008..Therefore, we conducted a meta-analysis summarizing the literature examining amygdala size obtained from magnetic resonance imaging in bipolar youths and adults... - Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy studyMelissa P DelBello
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Neuropsychopharmacology 31:1264-73. 2006..Additionally, olanzapine-induced increases in choline may lead to alteration of abnormalities in cell membrane metabolism or second messenger pathways that are thought to be involved in the pathophysiology of bipolar disorder... - Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for maniaStephen M Strakowski
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
Arch Gen Psychiatry 62:851-8. 2005..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome... - Outcome following a first manic episode: cross-national US and Taiwan comparisonStephen M Strakowski
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 9:820-7. 2007..Therefore, the aim of this study was to identify differential and shared outcome predictors in first-episode manic bipolar patients in Cincinnati, OH, USA and Taipei, Taiwan... - Progression of amygdala volumetric abnormalities in adolescents after their first manic episodeSamantha M Bitter
Research, Observation, Service, Education ROSE Program, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
J Am Acad Child Adolesc Psychiatry 50:1017-26. 2011.... - Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot studyMark W DiFrancesco
Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Arthritis Rheum 56:4151-63. 2007.... - Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging studyRobert K McNamara
Department of Psychiatry, Center for Imaging Research, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
Am J Clin Nutr 91:1060-7. 2010..However, the effects of DHA supplementation on functional cortical activity in human subjects are unknown... - A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorderMelissa P DelBello
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 68:789-95. 2007..To investigate the effectiveness and tolerability of quetiapine for the treatment of adolescents at high risk for developing bipolar I disorder... - Changes in gray matter volume in patients with bipolar disorderCaleb M Adler
Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Biol Psychiatry 58:151-7. 2005..Voxel based morphometry (VBM) allows a more exploratory analysis without the necessity for predefined anatomic boundaries. In this study we utilized VBM to compare gray matter volume between groups of bipolar and healthy subjects... - The effects of ziprasidone on prefrontal and amygdalar activation in manic youth with bipolar disorderMarguerite Reid Schneider
Physician Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, Neuroscience Graduate Program, University of Cincinnati, Cincinnati, Ohio, U S A
Isr J Psychiatry Relat Sci 49:112-20. 2012.... - Progressive neurostructural changes in adolescent and adult patients with bipolar disorderMegan E Lisy
Division of Bipolar Disorder Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
Bipolar Disord 13:396-405. 2011..In this study we compared baseline and follow-up scans in groups of bipolar disorder and healthy subjects. We hypothesized bipolar disorder subjects would demonstrate significant GMV changes over time... - Changes in neuronal activation in patients with bipolar disorder during performance of a working memory taskCaleb M Adler
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 6:540-9. 2004..We hypothesized that patients with bipolar disorder would demonstrate changes in neuronal activation in specific regions forming part of the working memory network... - Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorderJeffrey R Strawn
Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
Early Interv Psychiatry 4:169-73. 2010..To examine the prevalence of trauma exposure as well as the rates and effects of post-traumatic stress disorder (PTSD) in adolescents with bipolar disorder following a first manic episode... - Evidence of anterior temporal atrophy in college-level soccer playersJohn Adams
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Clin J Sport Med 17:304-6. 2007..In this study, we employed newer imaging techniques to examine brain changes in younger soccer players. We hypothesized that soccer players would demonstrate evidence of neurologic injury consistent with multiple frontal head blows... - Neuroprogression in bipolar disorderMarguerite Reid Schneider
Physician Scientist Training Program, Neuroscience Graduate Program Department, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
Bipolar Disord 14:356-74. 2012..The aim of our review is to examine the extant literature for developmental and progressive structural and functional changes in individuals with and at risk for bipolar disorder... - MRI analysis of cerebellar vermal abnormalities in bipolar disorderNeil P Mills
Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 162:1530-2. 2005..The authors sought to expand previous findings of vermal abnormalities in bipolar disorder patients... - Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging studyCaleb M Adler
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Bipolar Disord 6:197-203. 2004..In this study we utilized diffusion tensor imaging (DTI) to examine prefrontal white matter in patients with bipolar disorder... - Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorderMelissa P DelBello
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Ave, P O Box 670559, Cincinnati, OH 45267 0559, USA
J Affect Disord 82:S79-88. 2004..Additionally, we hypothesized that the groups would exhibit a similar decline in task performance as level of task difficulty increased and that within each level of task difficulty there would be similar performance among groups... - Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorderStephen M Strakowski
Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Am J Psychiatry 159:1841-7. 2002..In addition, it is unknown whether ventriculomegaly in bipolar disorder reflects acquired volume loss or underdevelopment of periventricular structures... - Morphometric magnetic resonance imaging in psychiatryDavid E Fleck
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45267 0559, USA
Top Magn Reson Imaging 19:131-42. 2008..However, advances in outcome and treatment monitoring show considerably more promise for rapid application in psychiatry... - A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent maniaMelissa P DelBello
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Am Acad Child Adolesc Psychiatry 45:305-13. 2006..To determine the comparative efficacy of quetiapine and divalproex for the treatment of adolescent mania... - Open-label lithium for the treatment of adolescents with bipolar depressionNick C Patel
College of Pharmacy and Department of Psychiatry, University of Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 45:289-97. 2006..We hypothesized that patients receiving open-label treatment with lithium during a 6-week period would experience a statistically and clinically significant decrease in depressive symptoms and tolerate lithium treatment fairly well... - Cigarette smoking and impulsivity in bipolar disorderJaimee L Heffner
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
Bipolar Disord 14:735-42. 2012..The goal of this study was to examine the association between impulsivity and the initiation or maintenance of smoking in bipolar disorder... - Boundaries of schizophreniaCaleb M Adler
Department of Psychiatry, Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Psychiatr Clin North Am 26:1-23. 2003..The long-standing debate as to the boundaries of schizophrenia is ultimately must await the eventual further elaboration of the underlying causes of schizophrenia and other psychotic disorders... - Atypical antipsychotics in the treatment of bipolar disorderStephen M Strakowski
Department of Psychiatry, University of Cincinnati College of Medicine, PO Box 670559, Cincinnati, OH 45267 0559, USA
Expert Opin Pharmacother 4:751-60. 2003..Atypical antipsychotics offer different side effect profiles than older antipsychotics, which may be of benefit for some patients. Consequently, atypical antipsychotics provide an important treatment option for bipolar patients... - Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?Stephen M Strakowski
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Bipolar Disord 4:80-8. 2002..This hypothesis remains speculative as much more research is needed to specifically examine how morphometric brain abnormalities translate into the neurophysiologic deficits that produce mood disorders... - Decreased brain volume in adults with childhood lead exposureKim M Cecil
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
PLoS Med 5:e112. 2008..In this study, we examined the relationship between childhood lead exposure and adult brain volume using magnetic resonance imaging (MRI). We also explored how volume changes correlate with historic neuropsychological assessments... - Ziprasidone-induced acute dystonic reactions in patients with bipolar disorderShannon K Weinstein
J Clin Psychiatry 67:327-8. 2006 - Acute dystonia associated with aripiprazole in a childManpreet K Singh
J Am Acad Child Adolesc Psychiatry 46:306-7. 2007 - Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI studyMichael A Cerullo
Schizophr Res 97:294-6. 2007 - Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapineJeffrey R Strawn
J Child Adolesc Psychopharmacol 18:116-8. 2008 - Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithiumNick C Patel
College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, Georgia 30912 2450, USA
J Child Adolesc Psychopharmacol 18:132-9. 2008..This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression... - Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesiaCaleb M Adler
Experimental Therapeutics Branch, National Institute of Mental Health/NIH, Bethesda, MD, USA
Neuropsychopharmacology 26:295-300. 2002..More research is needed to unravel the neurobiology of this debilitating disorder...