Caleb M Adler

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Changes in gray matter volume in patients with bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Biol Psychiatry 58:151-7. 2005
  2. ncbi request reprint Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task
    Caleb M Adler
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Bipolar Disord 7:577-88. 2005
  3. ncbi request reprint Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task
    Caleb M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 6:540-9. 2004
  4. ncbi request reprint Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study
    Caleb M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 6:197-203. 2004
  5. ncbi request reprint Boundaries of schizophrenia
    Caleb M Adler
    Department of Psychiatry, Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Psychiatr Clin North Am 26:1-23. 2003
  6. ncbi request reprint Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Affect Disord 100:S15-22. 2007
  7. ncbi request reprint Changes in neuronal activation with increasing attention demand in healthy volunteers: an fMRI study
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Synapse 42:266-72. 2001
  8. ncbi request reprint Age-related changes in regional activation during working memory in young adults: an fMRI study
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Synapse 42:252-7. 2001
  9. ncbi request reprint Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study
    Caleb M Adler
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 163:322-4. 2006
  10. ncbi request reprint fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Avenue, OH 45267 0559, USA
    J Psychiatr Res 34:317-24. 2000

Detail Information

Publications81

  1. ncbi request reprint Changes in gray matter volume in patients with bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Biol Psychiatry 58:151-7. 2005
    ..Voxel based morphometry (VBM) allows a more exploratory analysis without the necessity for predefined anatomic boundaries. In this study we utilized VBM to compare gray matter volume between groups of bipolar and healthy subjects...
  2. ncbi request reprint Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task
    Caleb M Adler
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Bipolar Disord 7:577-88. 2005
    ..In this study we utilized functional magnetic resonance imaging (fMRI) to compare activation patterns during performance of a simple attention task between bipolar adolescents with and without ADHD...
  3. ncbi request reprint Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task
    Caleb M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 6:540-9. 2004
    ..We hypothesized that patients with bipolar disorder would demonstrate changes in neuronal activation in specific regions forming part of the working memory network...
  4. ncbi request reprint Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study
    Caleb M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 6:197-203. 2004
    ..In this study we utilized diffusion tensor imaging (DTI) to examine prefrontal white matter in patients with bipolar disorder...
  5. ncbi request reprint Boundaries of schizophrenia
    Caleb M Adler
    Department of Psychiatry, Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Psychiatr Clin North Am 26:1-23. 2003
    ..The long-standing debate as to the boundaries of schizophrenia is ultimately must await the eventual further elaboration of the underlying causes of schizophrenia and other psychotic disorders...
  6. ncbi request reprint Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Affect Disord 100:S15-22. 2007
    ..To review the safety/tolerability of quetiapine in four placebo-controlled studies in patients with bipolar I disorder experiencing acute mania...
  7. ncbi request reprint Changes in neuronal activation with increasing attention demand in healthy volunteers: an fMRI study
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Synapse 42:266-72. 2001
    ....
  8. ncbi request reprint Age-related changes in regional activation during working memory in young adults: an fMRI study
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Synapse 42:252-7. 2001
    ....
  9. ncbi request reprint Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study
    Caleb M Adler
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 163:322-4. 2006
    ..In this study the authors utilized diffusion tensor imaging to study white matter tracts of adolescents in their first episode of mania to address whether abnormalities are present in early bipolar disorder...
  10. ncbi request reprint fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder
    C M Adler
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Avenue, OH 45267 0559, USA
    J Psychiatr Res 34:317-24. 2000
    ..To address this, we examined the effects of symptom induction on fMRI neural activation in medication-free patients with OCD...
  11. ncbi request reprint Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia
    C M Adler
    Experimental Therapeutics Branch, NIMH, Bethesda, MD, USA
    Am J Psychiatry 156:1646-9. 1999
    ..This study sought to determine whether thought disorder induced in healthy volunteers by the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine resembles the thought disorder found in patients with schizophrenia...
  12. ncbi request reprint Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study
    Caleb M Adler
    Division of Bipolar Disorder Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    J Clin Psychopharmacol 33:528-32. 2013
    ..These data support suggestions that therapeutic effects of quetiapine involve metabolic effects on specific prefrontal regions...
  13. pmc A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:175-84. 2012
    ..To further understand the role of the amygdala in the generation of mood symptoms, we used functional magnetic resonance imaging (fMRI) to examine a group of patients with bipolar I disorder longitudinally...
  14. doi request reprint The functional neuroanatomy of bipolar disorder
    Michael A Cerullo
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Int Rev Psychiatry 21:314-22. 2009
    ..Additionally, most studies were confounded by patients taking psychotropic medications. Nonetheless, from this work an anterior limbic over-activation model of bipolar disorder is emerging...
  15. ncbi request reprint A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA
    Neuropsychobiology 67:224-9. 2013
    ..This study used proton magnetic resonance spectroscopy (¹H MRS) to evaluate the neurochemistry of the anterior cingulate cortex (ACC) in adolescents with generalized anxiety disorder (GAD)...
  16. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
    ....
  17. ncbi request reprint Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder
    Wen Jang Chu
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Psychiatry Res 213:230-4. 2013
    ....
  18. doi request reprint Low docosahexaenoic acid status is associated with reduced indices in cortical integrity in the anterior cingulate of healthy male children: a 1H MRS Study
    Robert K McNamara
    Department of Psychiatry and Behavioral Neuroscience, Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Nutr Neurosci 16:183-90. 2013
    ..These data indicate that low-DHA status is associated with reduced indices of metabolic function in the ACC and slower reaction time during sustained attention in developing male children...
  19. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
    ..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied...
  20. pmc Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559 USA
    Biol Psychiatry 69:381-8. 2011
    ..We used functional magnetic resonance imaging (fMRI) to study manic bipolar subjects as they performed a cognitive task designed to examine the ventrolateral prefrontal emotional arousal network...
  21. pmc Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    J Affect Disord 133:333-9. 2011
    ..The aim of this study was to examine whether the neural correlates of motor impulsivity are distinct in patients with mixed mania...
  22. ncbi request reprint Neuroanatomic abnormalities in adolescents with generalized anxiety disorder: a voxel-based morphometry study
    Jeffrey R Strawn
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    Depress Anxiety 30:842-8. 2013
    ..Despite recent data implicating functional abnormalities in the neurocircuitry underlying emotional processing in pediatric anxiety disorders, little is known regarding neurostructural abnormalities within these systems...
  23. doi request reprint Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study
    Jeffrey R Strawn
    University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
    J Am Acad Child Adolesc Psychiatry 51:642-51. 2012
    ....
  24. pmc Neuroanatomical characterization of child offspring of bipolar parents
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, OH 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 47:526-31. 2008
    ..We hypothesized that at-risk (AR) children would exhibit abnormalities in brain regions that are involved in mood regulation...
  25. ncbi request reprint Brain network dysfunction in bipolar disorder
    Caleb M Adler
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    CNS Spectr 11:312-20; quiz 323-4. 2006
    ..As neuroimaging techniques continue to improve, the underlying neural basis of bipolar disorder will be clarified...
  26. pmc Impulsivity across the course of bipolar disorder
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
    Bipolar Disord 12:285-97. 2010
    ..To determine whether abnormalities of impulse control persist across the course of bipolar disorder, thereby representing potential state markers and endophenotypes...
  27. ncbi request reprint The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s)
    Drew H Barzman
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
    J Child Adolesc Psychopharmacol 16:665-70. 2006
    ..The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders...
  28. ncbi request reprint The neurophysiology of childhood and adolescent bipolar disorder
    Melissa P DelBello
    Division of Bipolar Disorder Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    CNS Spectr 11:298-311. 2006
    ....
  29. ncbi request reprint Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task
    Stephen M Strakowski
    Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    Am J Psychiatry 162:1697-705. 2005
    ..Cognitive probes, coupled with neuroimaging, provide an approach toward clarifying the neurophysiology of bipolar disorder...
  30. ncbi request reprint A pilot study of alterations in high energy phosphoryl compounds and intracellular pH in unmedicated adolescents with bipolar disorder
    Wade A Weber
    Department of Psychiatry and Behavioral Neuroscience, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    J Affect Disord 150:1109-13. 2013
    ....
  31. doi request reprint Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry, and The Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Early Interv Psychiatry 3:189-97. 2009
    ..In contrast, we hypothesized that bipolar subjects would show altered brain activation in regions responsible for emotionally homeostasis, including the striatum and amygdala...
  32. pmc Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Early Interv Psychiatry 2:225-33. 2008
    ..Impulsivity is common in bipolar disorder, especially during mania. Understanding the functional neuroanatomy of response inhibition, one component of impulsivity, might clarify the neural substrate of bipolar disorder...
  33. ncbi request reprint Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode
    Melissa P DelBello
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 164:582-90. 2007
    ..The aim of this study was to examine the 12-month outcome of bipolar adolescents following an initial hospitalization for a manic or mixed episode...
  34. pmc Lithium treatment effects on Myo-inositol in adolescents with bipolar depression
    Nick C Patel
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0004, USA
    Biol Psychiatry 60:998-1004. 2006
    ..This study used proton magnetic resonance spectroscopy (1H MRS) to identify the in vivo effects of lithium on myo-inositol (mI) concentrations in adolescent bipolar depression...
  35. ncbi request reprint Voxel-based study of structural changes in first-episode patients with bipolar disorder
    Caleb M Adler
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Biol Psychiatry 61:776-81. 2007
    ..In this study, we used VBM to explore structural brain changes in first-episode bipolar patients...
  36. ncbi request reprint Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Arch Gen Psychiatry 62:851-8. 2005
    ..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome...
  37. ncbi request reprint Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder
    Stephen M Strakowski
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 159:1841-7. 2002
    ..In addition, it is unknown whether ventriculomegaly in bipolar disorder reflects acquired volume loss or underdevelopment of periventricular structures...
  38. pmc Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders
    Kelly Jarvis
    University of Cincinnati, Division of Bipolar Disorders Research, Department of Psychiatry, Cincinnati, OH 45267 0559, USA
    J Child Adolesc Psychopharmacol 18:557-63. 2008
    ..In this pilot study, we compared brain morphometry between bipolar adolescents with co-occurring cannabis use disorders (CUD) and bipolar adolescents without any substance use disorder...
  39. ncbi request reprint A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 260 Stetson Street, Suite 3200, ML 559, Cincinnati, OH 45219, USA
    Bipolar Disord 11:483-93. 2009
    ..To conduct a pilot study comparing the effects of quetiapine and placebo for the treatment of depressive episodes in adolescents with bipolar I disorder...
  40. pmc Conflict monitoring and adaptation in individuals at familial risk for developing bipolar disorder
    Luis R Patino
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 15:264-71. 2013
    ..To examine conflict monitoring and conflict-driven adaptation in individuals at familial risk for developing bipolar disorder...
  41. pmc Cigarette smoking and impulsivity in bipolar disorder
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    Bipolar Disord 14:735-42. 2012
    ..The goal of this study was to examine the association between impulsivity and the initiation or maintenance of smoking in bipolar disorder...
  42. pmc The functional neuroanatomy of bipolar disorder: a consensus model
    Stephen M Strakowski
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 14:313-25. 2012
    ....
  43. pmc Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale
    Jayasree J Nandagopal
    Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 21:465-8. 2011
    ....
  44. ncbi request reprint Outcome following a first manic episode: cross-national US and Taiwan comparison
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:820-7. 2007
    ..Therefore, the aim of this study was to identify differential and shared outcome predictors in first-episode manic bipolar patients in Cincinnati, OH, USA and Taipei, Taiwan...
  45. ncbi request reprint A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder
    Stephen M Strakowski
    Bipolar and Psychotic Disorders Research Program, University of Cincinnati College of Medicine, OH 45267 0583, USA
    Neuropsychopharmacology 29:1734-40. 2004
    ..Since the differences occurred in euthymia, they may represent trait, rather than state, abnormalities of brain function in bipolar disorder...
  46. ncbi request reprint Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Neuropsychopharmacology 31:1264-73. 2006
    ..Additionally, olanzapine-induced increases in choline may lead to alteration of abnormalities in cell membrane metabolism or second messenger pathways that are thought to be involved in the pathophysiology of bipolar disorder...
  47. doi request reprint Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder
    Jonathan C Pfeifer
    Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Am Acad Child Adolesc Psychiatry 47:1289-98. 2008
    ..Therefore, we conducted a meta-analysis summarizing the literature examining amygdala size obtained from magnetic resonance imaging in bipolar youths and adults...
  48. ncbi request reprint Risk and protective factors associated with substance use disorders in adolescents with first-episode mania
    Jacob R Stephens
    Research, Observation, Service, Education ROSE Program and the Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH
    J Am Acad Child Adolesc Psychiatry 53:771-9. 2014
    ..The purpose of this study was to identify predictors of developing SUDs after a first manic episode...
  49. pmc Progression of amygdala volumetric abnormalities in adolescents after their first manic episode
    Samantha M Bitter
    Research, Observation, Service, Education ROSE Program, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    J Am Acad Child Adolesc Psychiatry 50:1017-26. 2011
    ....
  50. pmc Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study
    Robert K McNamara
    Department of Psychiatry, Center for Imaging Research, Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Am J Clin Nutr 91:1060-7. 2010
    ..However, the effects of DHA supplementation on functional cortical activity in human subjects are unknown...
  51. ncbi request reprint A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania
    Melissa P DelBello
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Am Acad Child Adolesc Psychiatry 45:305-13. 2006
    ..To determine the comparative efficacy of quetiapine and divalproex for the treatment of adolescent mania...
  52. pmc Decreased brain volume in adults with childhood lead exposure
    Kim M Cecil
    Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS Med 5:e112. 2008
    ..In this study, we examined the relationship between childhood lead exposure and adult brain volume using magnetic resonance imaging (MRI). We also explored how volume changes correlate with historic neuropsychological assessments...
  53. ncbi request reprint Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study
    Mark W DiFrancesco
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Arthritis Rheum 56:4151-63. 2007
    ....
  54. ncbi request reprint Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder
    Melissa P DelBello
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Ave, P O Box 670559, Cincinnati, OH 45267 0559, USA
    J Affect Disord 82:S79-88. 2004
    ..Additionally, we hypothesized that the groups would exhibit a similar decline in task performance as level of task difficulty increased and that within each level of task difficulty there would be similar performance among groups...
  55. ncbi request reprint A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder
    Melissa P DelBello
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Clin Psychiatry 68:789-95. 2007
    ..To investigate the effectiveness and tolerability of quetiapine for the treatment of adolescents at high risk for developing bipolar I disorder...
  56. ncbi request reprint The effects of ziprasidone on prefrontal and amygdalar activation in manic youth with bipolar disorder
    Marguerite Reid Schneider
    Physician Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, Neuroscience Graduate Program, University of Cincinnati, Cincinnati, Ohio, U S A
    Isr J Psychiatry Relat Sci 49:112-20. 2012
    ....
  57. ncbi request reprint Progressive neurostructural changes in adolescent and adult patients with bipolar disorder
    Megan E Lisy
    Division of Bipolar Disorder Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 13:396-405. 2011
    ..In this study we compared baseline and follow-up scans in groups of bipolar disorder and healthy subjects. We hypothesized bipolar disorder subjects would demonstrate significant GMV changes over time...
  58. ncbi request reprint Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Early Interv Psychiatry 4:169-73. 2010
    ..To examine the prevalence of trauma exposure as well as the rates and effects of post-traumatic stress disorder (PTSD) in adolescents with bipolar disorder following a first manic episode...
  59. ncbi request reprint Evidence of anterior temporal atrophy in college-level soccer players
    John Adams
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Clin J Sport Med 17:304-6. 2007
    ..In this study, we employed newer imaging techniques to examine brain changes in younger soccer players. We hypothesized that soccer players would demonstrate evidence of neurologic injury consistent with multiple frontal head blows...
  60. pmc Is depression simply a nonspecific response to brain injury?
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Curr Psychiatry Rep 15:386. 2013
    ....
  61. doi request reprint Neuroprogression in bipolar disorder
    Marguerite Reid Schneider
    Physician Scientist Training Program, Neuroscience Graduate Program Department, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:356-74. 2012
    ..The aim of our review is to examine the extant literature for developmental and progressive structural and functional changes in individuals with and at risk for bipolar disorder...
  62. ncbi request reprint MRI analysis of cerebellar vermal abnormalities in bipolar disorder
    Neil P Mills
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 162:1530-2. 2005
    ..The authors sought to expand previous findings of vermal abnormalities in bipolar disorder patients...
  63. doi request reprint Morphometric magnetic resonance imaging in psychiatry
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45267 0559, USA
    Top Magn Reson Imaging 19:131-42. 2008
    ..However, advances in outcome and treatment monitoring show considerably more promise for rapid application in psychiatry...
  64. pmc Prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Electronic address
    Psychiatry Res 210:857-62. 2013
    ..Further research to elucidate mechanisms and develop interventions to address early, entrenched patterns of co-use of tobacco and marijuana is warranted. ..
  65. pmc Cigarette smoking and its relationship to mood disorder symptoms and co-occurring alcohol and cannabis use disorders following first hospitalization for bipolar disorder
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Cincinnati, OH, USA
    Bipolar Disord 14:99-108. 2012
    ..In the present study, we prospectively evaluated the course of BD, alcohol use disorders, and cannabis use disorders in relation to smoking and examined the relationship between smoking abstinence and changes in mood...
  66. ncbi request reprint Atypical antipsychotics in the treatment of bipolar disorder
    Stephen M Strakowski
    Department of Psychiatry, University of Cincinnati College of Medicine, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Expert Opin Pharmacother 4:751-60. 2003
    ..Atypical antipsychotics offer different side effect profiles than older antipsychotics, which may be of benefit for some patients. Consequently, atypical antipsychotics provide an important treatment option for bipolar patients...
  67. ncbi request reprint Open-label lithium for the treatment of adolescents with bipolar depression
    Nick C Patel
    College of Pharmacy and Department of Psychiatry, University of Cincinnati, OH 45267 0004, USA
    J Am Acad Child Adolesc Psychiatry 45:289-97. 2006
    ..We hypothesized that patients receiving open-label treatment with lithium during a 6-week period would experience a statistically and clinically significant decrease in depressive symptoms and tolerate lithium treatment fairly well...
  68. ncbi request reprint Human response to repeated low-dose d-amphetamine: evidence for behavioral enhancement and tolerance
    S M Strakowski
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Neuropsychopharmacology 25:548-54. 2001
    ..These effects were greater in women. Progressive changes in subjective responses following repeated d-amphetamine administration may occur in healthy human subjects, although this effect may be greater for women...
  69. ncbi request reprint Comparative efficacy and tolerability of drug treatments for bipolar disorder
    S M Strakowski
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    CNS Drugs 15:701-18. 2001
    ..Identifying a specific treatment for a specific patient requires a careful individualised assessment of the risk of adverse effects for that patient's unique circumstances...
  70. ncbi request reprint Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response
    A F Breier
    Experimental Therapeutics Branch, Division of Intramural Research Programs, NIMH, Bethesda, MD, USA
    Am J Psychiatry 156:294-8. 1999
    ....
  71. ncbi request reprint The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings
    S M Strakowski
    Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Mol Psychiatry 10:105-16. 2005
    ..Future prospective and longitudinal studies focusing on these specific relationships are necessary to clarify the functional neuroanatomy of bipolar disorder...
  72. ncbi request reprint Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?
    Stephen M Strakowski
    Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
    Bipolar Disord 4:80-8. 2002
    ..This hypothesis remains speculative as much more research is needed to specifically examine how morphometric brain abnormalities translate into the neurophysiologic deficits that produce mood disorders...
  73. ncbi request reprint Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach
    A Breier
    Experimental Therapeutics Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Synapse 29:142-7. 1998
    ..The implications of this brain imaging method for studies of schizophrenia and the mechanism of action of antipsychotic drugs are discussed...
  74. ncbi request reprint Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia
    Caleb M Adler
    Experimental Therapeutics Branch, National Institute of Mental Health NIH, Bethesda, MD, USA
    Neuropsychopharmacology 26:295-300. 2002
    ..More research is needed to unravel the neurobiology of this debilitating disorder...
  75. ncbi request reprint Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia
    I Elman
    Experimental Therapeutics Branch, NIMH, National Institutes of Health, Bethesda, MD, USA
    Am J Psychiatry 155:979-81. 1998
    ..The authors examined the effects of acute metabolic stress induced by 2-deoxy-D-glucose (2-DG) on pituitary-adrenal axis activation...
  76. ncbi request reprint The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers
    I Elman
    Experimental Therapeutics Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Brain Res 815:243-9. 1999
    ....
  77. ncbi request reprint Acute dystonia associated with aripiprazole in a child
    Manpreet K Singh
    J Am Acad Child Adolesc Psychiatry 46:306-7. 2007
  78. doi request reprint Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine
    Jeffrey R Strawn
    J Child Adolesc Psychopharmacol 18:116-8. 2008
  79. ncbi request reprint Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI study
    Michael A Cerullo
    Schizophr Res 97:294-6. 2007
  80. ncbi request reprint Ziprasidone-induced acute dystonic reactions in patients with bipolar disorder
    Shannon K Weinstein
    J Clin Psychiatry 67:327-8. 2006
  81. doi request reprint Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium
    Nick C Patel
    College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, Georgia 30912 2450, USA
    J Child Adolesc Psychopharmacol 18:132-9. 2008
    ..This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression...

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