B Adkins

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi request reprint Autoantibodies to T-lineage cells in aged mice
    B Adkins
    Department of Pathology, University of Miami School of Medicine, FL 33136, USA
    Mech Ageing Dev 103:147-64. 1998
  2. ncbi request reprint T-cell function in newborn mice and humans
    B Adkins
    Dept of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    Immunol Today 20:330-5. 1999
  3. ncbi request reprint Apoptosis of murine neonatal T cells
    B Adkins
    Department of Microbiology and Immunology R138, University of Miami Medical School, FL 33101, USA
    Int Rev Immunol 18:465-84. 1999
  4. ncbi request reprint Development of neonatal Th1/Th2 function
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, FL 33136, USA
    Int Rev Immunol 19:157-71. 2000
  5. ncbi request reprint Exclusive Th2 primary effector function in spleens but mixed Th1/Th2 function in lymph nodes of murine neonates
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    J Immunol 164:2347-53. 2000
  6. ncbi request reprint The generation of Th memory in neonates versus adults: prolonged primary Th2 effector function and impaired development of Th1 memory effector function in murine neonates
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    J Immunol 166:918-25. 2001
  7. ncbi request reprint Choroid plexus selectively accumulates T-lymphocytes in normal controls and after peripheral immune activation
    C K Petito
    Department of Pathology, University of Miami, School of Medicine, 1550 NW 10th Avenue, Miami, FL 33136, USA
    J Neuroimmunol 162:19-27. 2005
  8. ncbi request reprint Monoclonal antibodies to the common gamma-chain as cytokine receptor antagonists in vivo: effect on intrathymic and intestinal intraepithelial T lymphocyte development
    T R Malek
    Department of Microbiology and Immunology, University of Miami School of Medicine, Florida 33101, USA
    J Leukoc Biol 63:643-9. 1998
  9. ncbi request reprint Developmental regulation of IL-4, IL-2, and IFN-gamma production by murine peripheral T lymphocytes
    B Adkins
    Department of Pathology, University of Miami Medical School, FL 33101
    J Immunol 151:6617-26. 1993
  10. pmc Toxin levels in serum correlate with the development of staphylococcal scalded skin syndrome in a murine model
    L R Plano
    Departments of Pediatrics, University of Miami School of Medicine, Miami, Florida 33101, USA
    Infect Immun 69:5193-7. 2001

Collaborators

  • T R Malek
  • A Ghanei
  • C K Petito
  • L R Plano
  • B Roberts
  • I Khamis
  • M McCarthy
  • C M Collins
  • R Ewing
  • M Woischnik

Detail Information

Publications11

  1. ncbi request reprint Autoantibodies to T-lineage cells in aged mice
    B Adkins
    Department of Pathology, University of Miami School of Medicine, FL 33136, USA
    Mech Ageing Dev 103:147-64. 1998
    ..These results lead to the proposal that the presence of anti-T-lineage autoantibodies in vivo interferes with normal T-cell development and/or function in aged animals...
  2. ncbi request reprint T-cell function in newborn mice and humans
    B Adkins
    Dept of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    Immunol Today 20:330-5. 1999
    ..Here, Becky Adkins discusses this issue in the light of recent data indicating that T cells in neonates are developmentally mature in their capacity to mount protective Th1-type and cytotoxic T lymphocyte responses...
  3. ncbi request reprint Apoptosis of murine neonatal T cells
    B Adkins
    Department of Microbiology and Immunology R138, University of Miami Medical School, FL 33101, USA
    Int Rev Immunol 18:465-84. 1999
    ..This review summarizes our current state of knowledge of apoptosis of murine neonatal T cells and discusses the possible impact(s) of this apoptosis on neonatal immune responses in vivo...
  4. ncbi request reprint Development of neonatal Th1/Th2 function
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, FL 33136, USA
    Int Rev Immunol 19:157-71. 2000
    ..A major challenge in the field of developmental immunology is to understand why the 'default' response for neonates is Th2 function. Cell intrinsic as well as environmental influences may contribute to Th2 skewing in neonates...
  5. ncbi request reprint Exclusive Th2 primary effector function in spleens but mixed Th1/Th2 function in lymph nodes of murine neonates
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    J Immunol 164:2347-53. 2000
    ....
  6. ncbi request reprint The generation of Th memory in neonates versus adults: prolonged primary Th2 effector function and impaired development of Th1 memory effector function in murine neonates
    B Adkins
    Department of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA
    J Immunol 166:918-25. 2001
    ..These experiments demonstrated that neonates are selectively impaired in the development of Th1 memory effector function. Together, these results indicate that neonates are biased to Th2 function at all phases of an immune response...
  7. ncbi request reprint Choroid plexus selectively accumulates T-lymphocytes in normal controls and after peripheral immune activation
    C K Petito
    Department of Pathology, University of Miami, School of Medicine, 1550 NW 10th Avenue, Miami, FL 33136, USA
    J Neuroimmunol 162:19-27. 2005
    ..T cell apoptosis was absent. These results show preferential T-lymphocyte migration to CPx over brain and suggest that brain T cells may be derived from the CPx by direct migration or by cerebrospinal fluid dissemination...
  8. ncbi request reprint Monoclonal antibodies to the common gamma-chain as cytokine receptor antagonists in vivo: effect on intrathymic and intestinal intraepithelial T lymphocyte development
    T R Malek
    Department of Microbiology and Immunology, University of Miami School of Medicine, Florida 33101, USA
    J Leukoc Biol 63:643-9. 1998
    ..However, the inhibitory activity of the anti-deltac mAb in the chimeric mouse model suggests that additional gamma cutilizing cytokines regulate the development of the remaining subsets of IEL...
  9. ncbi request reprint Developmental regulation of IL-4, IL-2, and IFN-gamma production by murine peripheral T lymphocytes
    B Adkins
    Department of Pathology, University of Miami Medical School, FL 33101
    J Immunol 151:6617-26. 1993
    ..Thus, the progression to adultlike lymphokine production involves a combination of changes in the types of lymphokines produced and in the magnitude of the response to activation signals...
  10. pmc Toxin levels in serum correlate with the development of staphylococcal scalded skin syndrome in a murine model
    L R Plano
    Departments of Pediatrics, University of Miami School of Medicine, Miami, Florida 33101, USA
    Infect Immun 69:5193-7. 2001
    ..Thus, whereas the adaptive immune response is not needed for protection of adult mice from SSSS, efficient clearance of the toxin from the bloodstream is a critical factor...
  11. ncbi request reprint CD4+ and CD8+ cells accumulate in the brains of acquired immunodeficiency syndrome patients with human immunodeficiency virus encephalitis
    C K Petito
    Department of Pathology, University of Miami School of Medicine, Florida 33136, USA
    J Neurovirol 9:36-44. 2003
    ..The perineuronal location of CD4+ cells provides the potential for lymphocyte-mediated neuronal injury or trans-receptor-mediated neuronal infection...