Opeolu Adeoye

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. pmc A matched comparison of eptifibatide plus rt-PA versus rt-PA alone in acute ischemic stroke
    Opeolu Adeoye
    University of Cincinnati Neuroscience Institute, Cincinnati, Ohio Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio Electronic address
    J Stroke Cerebrovasc Dis 23:e313-5. 2014
  2. pmc Peripheral monocyte count is associated with case fatality after intracerebral hemorrhage
    Opeolu Adeoye
    UC Neuroscience Institute, Cincinnati, Ohio Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio Electronic address
    J Stroke Cerebrovasc Dis 23:e107-11. 2014
  3. pmc Efficiency of enrollment in a successful phase II acute stroke clinical trial
    Opeolu Adeoye
    Department of Emergency Medicine and Neurosurgery, University of Cincinnati Neuroscience Institute, Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 21:667-72. 2012
  4. doi request reprint Advances in the management of intracerebral hemorrhage
    Opeolu Adeoye
    Department of Emergency Medicine, Division of Neurocritical Care, University of Cincinnati Medical Center, 231 Albert Sabin Way, ML 0769, Cincinnati, OH 45267 0525, USA
    Nat Rev Neurol 6:593-601. 2010
  5. ncbi request reprint Recombinant tissue-type plasminogen activator use for ischemic stroke in the United States: a doubling of treatment rates over the course of 5 years
    Opeolu Adeoye
    UC Neuroscience Institute, Department of Emergency Medicine, 231 Albert Sabin Way, ML 0769, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 42:1952-5. 2011
  6. pmc How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?
    Opeolu Adeoye
    Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 41:2218-22. 2010
  7. doi request reprint The rate of hemicraniectomy for acute ischemic stroke is increasing in the United States
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0525, USA
    J Stroke Cerebrovasc Dis 20:251-4. 2011
  8. doi request reprint Trends in surgical management and mortality of intracerebral hemorrhage in the United States before and after the STICH trial
    Opeolu Adeoye
    Department of Emergency Medicine, UC Neuroscience Institute, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 13:82-6. 2010
  9. pmc Emergency medical services use by stroke patients: a population-based study
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Am J Emerg Med 27:141-5. 2009
  10. pmc Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Neurosurgery 63:1113-7; discussion 1117-8. 2008

Detail Information

Publications46

  1. pmc A matched comparison of eptifibatide plus rt-PA versus rt-PA alone in acute ischemic stroke
    Opeolu Adeoye
    University of Cincinnati Neuroscience Institute, Cincinnati, Ohio Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio Electronic address
    J Stroke Cerebrovasc Dis 23:e313-5. 2014
    ....
  2. pmc Peripheral monocyte count is associated with case fatality after intracerebral hemorrhage
    Opeolu Adeoye
    UC Neuroscience Institute, Cincinnati, Ohio Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio Electronic address
    J Stroke Cerebrovasc Dis 23:e107-11. 2014
    ..We examined total white blood cell (WBC) count, absolute monocyte count (AMC), and absolute neutrophil count (ANC) as potential readily available prognostic biomarkers in human ICH...
  3. pmc Efficiency of enrollment in a successful phase II acute stroke clinical trial
    Opeolu Adeoye
    Department of Emergency Medicine and Neurosurgery, University of Cincinnati Neuroscience Institute, Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 21:667-72. 2012
    ..We hypothesized that missed opportunities for enrollment of eligible patients occurred frequently, despite the success of the trial...
  4. doi request reprint Advances in the management of intracerebral hemorrhage
    Opeolu Adeoye
    Department of Emergency Medicine, Division of Neurocritical Care, University of Cincinnati Medical Center, 231 Albert Sabin Way, ML 0769, Cincinnati, OH 45267 0525, USA
    Nat Rev Neurol 6:593-601. 2010
    ..In this Review, we discuss clinical trials for ICH that have been completed in the past 10 years, the contributions of these studies to the clinical management of ICH, and the ongoing trials that might further improve clinical care...
  5. ncbi request reprint Recombinant tissue-type plasminogen activator use for ischemic stroke in the United States: a doubling of treatment rates over the course of 5 years
    Opeolu Adeoye
    UC Neuroscience Institute, Department of Emergency Medicine, 231 Albert Sabin Way, ML 0769, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 42:1952-5. 2011
    ..In 2004, 1.8% to 2.1% of AIS patients in the United States received rtPA. Given incentives from regulatory agencies and payors to increase rtPA use, we hypothesized that rtPA use in the United States would increase from 2005 to 2009...
  6. pmc How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?
    Opeolu Adeoye
    Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 41:2218-22. 2010
    ..We determined how frequently MRI/DWI was performed for TIA and ascertained the proportion of clinically defined TIA patients who had ischemic lesions on DWI in our community in 2005...
  7. doi request reprint The rate of hemicraniectomy for acute ischemic stroke is increasing in the United States
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0525, USA
    J Stroke Cerebrovasc Dis 20:251-4. 2011
    ..Publication of the landmark study did not appear to significantly change this rate. Future studies should investigate the appropriateness of patient selection and missed opportunities for treatment...
  8. doi request reprint Trends in surgical management and mortality of intracerebral hemorrhage in the United States before and after the STICH trial
    Opeolu Adeoye
    Department of Emergency Medicine, UC Neuroscience Institute, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 13:82-6. 2010
    ..Using a national hospital database, we determined trends in surgery for ICH before and after publication of STICH. We also determined trends in ICH mortality during the study period...
  9. pmc Emergency medical services use by stroke patients: a population-based study
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Am J Emerg Med 27:141-5. 2009
    ..In an epidemiological study, we determined the proportion of stroke patients who used EMS, hypothesizing that demographics, stroke severity, stroke type, and location at stroke onset would be associated with EMS use...
  10. pmc Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Neurosurgery 63:1113-7; discussion 1117-8. 2008
    ..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005...
  11. pmc Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohort
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Neurocrit Care 9:237-41. 2008
    ..We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria...
  12. pmc Is ED disposition associated with intracerebral hemorrhage mortality?
    Opeolu Adeoye
    UC Neuroscience Institute, Cincinnati, OH 45267, USA
    Am J Emerg Med 29:391-5. 2011
    ..We also compared observed with expected mortality in transferred and nontransferred patients using published short-term mortality predictors for ICH...
  13. pmc The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial
    Arthur M Pancioli
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
    Stroke 39:3268-76. 2008
    ....
  14. pmc Age at stroke: temporal trends in stroke incidence in a large, biracial population
    Brett M Kissela
    University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Neurology 79:1781-7. 2012
    ..We hypothesized that stroke incidence in younger adults (age 20-54) increased over time, most notably between 1999 and 2005...
  15. pmc Trends in substance abuse preceding stroke among young adults: a population-based study
    Felipe de Los Ríos
    University of Cincinnati College of Medicine, Department of Neurology, and Cincinnati Children s Hospital, 260 Stetson St, Suite 2300, Cincinnati, OH 45267, USA
    Stroke 43:3179-83. 2012
    ..Approximately 5% of strokes occur in adults aged 18 to 44 years. Substance abuse is a prevalent risk factor for stroke in young adults. We sought to identify trends in substance abuse detection among stroke patients...
  16. pmc Patients living in impoverished areas have more severe ischemic strokes
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Stroke 43:2055-9. 2012
    ..However, predictors of initial stroke severity have not been well-described within a population. We hypothesized that poorer patients would have a higher initial stroke severity on presentation to medical attention...
  17. pmc Eligibility for Intravenous Recombinant Tissue-Type Plasminogen Activator Within a Population: The Effect of the European Cooperative Acute Stroke Study (ECASS) III Trial
    Felipe de Los Ríos la Rosa
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA
    Stroke 43:1591-5. 2012
    ..5 hours from symptom onset. The impact of the expanded time window on treatment rates has not been comprehensively evaluated in a population-based study...
  18. ncbi request reprint Distribution of National Institutes of Health stroke scale in the Cincinnati/Northern Kentucky Stroke Study
    Mathew Reeves
    From the Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI M R Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital, OH J K and Neuroscience Institute K A, C M, M F, D W, P K, S F, B K, D K, Department of Neurology K A, C M, M F, D W, P K, S F, B K, D K, and Department of Emergency Medicine O A, University of Cincinnati, OH
    Stroke 44:3211-3. 2013
    ..We describe the distribution of NIHSS in ischemic stroke cases from the Cincinnati/Northern Kentucky Stroke Study...
  19. pmc Ischemic stroke survivors' opinion regarding research utilizing exception from informed consent
    Dawn Kleindorfer
    University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Cerebrovasc Dis 32:321-6. 2011
    ..We obtained ischemic stroke survivors' opinions regarding hypothetical enrollment into a clinical trial at the time of their stroke without personal or proxy consent...
  20. pmc Combined approach to lysis utilizing eptifibatide and recombinant tissue plasminogen activator in acute ischemic stroke-enhanced regimen stroke trial
    Arthur M Pancioli
    Department of Emergency Medicine, University of Cincinnati Neuroscience Institute, Cincinnati, OH, USA
    Stroke 44:2381-7. 2013
    ..The Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke-Enhanced Regimen (CLEAR-ER) trial sought to determine the safety of a higher-dose regimen and to establish evidence for a phase III trial...
  21. pmc Diabetes mellitus: a risk factor for ischemic stroke in a large biracial population
    Jane C Khoury
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, 3333 Burnett Av, MLC 5041, Cincinnati, OH 45229, USA
    Stroke 44:1500-4. 2013
    ..With rising prevalence of diabetes mellitus in the past decade, we revisit the impact of diabetes mellitus on stroke incidence in the same population (≈1.3 million) 5 and 10 years later...
  22. pmc How often are patients with ischemic stroke eligible for decompressive hemicraniectomy?
    Ralph Rahme
    Department of Neurosurgery, University of Cincinnati, Cincinnati, OH 45267, USA
    Stroke 43:550-2. 2012
    ....
  23. pmc Which stroke symptoms prompt a 911 call? A population-based study
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    Am J Emerg Med 28:607-12. 2010
    ..Most studies have found that less than half of stroke/transient ischemic attack (TIA) events result in a 911 call. We sought to determine which symptoms prompt the public to call 911...
  24. doi request reprint Profiles of the National Institutes of Health Stroke Scale items as a predictor of patient outcome
    Heidi Sucharew
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Stroke 44:2182-7. 2013
    ..We examined whether grouping strokes by presence of individual NIHSS symptoms could provide prognostic information additional or alternative to the NIHSS total score...
  25. pmc Carotid artery stenosis as a cause of stroke
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Neuroepidemiology 40:36-41. 2013
    ..We determined the types of large-vessel atherosclerosis responsible for ischemic strokes in a population-based stroke study...
  26. pmc Withdrawal of antithrombotic agents and its impact on ischemic stroke occurrence
    Joseph P Broderick
    University of Cincinnati, Department of Neurology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center MSB 0525, Cincinnati, OH 45242, USA
    Stroke 42:2509-14. 2011
    ..These medications are also stopped by patients for various reasons such as cost, side effects, or unwillingness to take medication...
  27. pmc The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Stroke 40:1738-42. 2009
    ..We determined the number of patients that would be eligible for enrollment in hypothetical treatment trials for WICH using a population-based study...
  28. pmc Comparison of two depression measures for predicting stroke outcomes
    Lawson Wulsin
    University of Cincinnati, Department of Psychiatry, Cincinnati, OH 45267 0559, United States
    J Psychosom Res 72:175-9. 2012
    ..This study compared a measure of current symptoms of depression at the time of the stroke and a measure of lifetime history of depression for their ability to predict quality of life and functioning at 3 and 12 months after stroke...
  29. ncbi request reprint US geographic distribution of rt-PA utilization by hospital for acute ischemic stroke
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Ohio 45267 0525, USA
    Stroke 40:3580-4. 2009
    ..We describe the US geographic distribution of hospitals using rt-PA for acute ischemic stroke...
  30. pmc Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study
    Dawn O Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45242, USA
    Stroke 41:1326-31. 2010
    ..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005...
  31. ncbi request reprint Increasing use of computed tomographic perfusion and computed tomographic angiograms in acute ischemic stroke from 2006 to 2010
    Achala Vagal
    From the Departments of Radiology A V, Neurology D O K, R H, P K, Emergency Medicine O A, and Family Medicine K M, University of Cincinnati Medical Center, OH
    Stroke 45:1029-34. 2014
    ..Our objective was to study nationwide utilization trends of computed tomographic (CT) angiogram (CTA) and CT perfusion (CTP) in acute ischemic stroke and particularly in the context of use of reperfusion therapies...
  32. pmc The practice of carotid revascularization in a large metropolitan population
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 22:143-8. 2013
    ..Point estimates for perioperative risk after CEA were improved from previous studies but remained above the recommended benchmarks. The number of CAS procedures was low, but the perioperative risk was significant...
  33. pmc Antihypertensives are administered selectively in emergency department patients with subarachnoid hemorrhage
    Virginia Culyer
    Department of Emergency Medicine, University of Cincinnati Neuroscience Institute, University of Cincinnati, Cincinnati, Ohio Electronic address
    J Stroke Cerebrovasc Dis 22:1225-8. 2013
    ..In the absence of definitive evidence, current blood pressure management in local EDs appears reasonable. Further studies of blood pressure management in acute SAH are warranted...
  34. pmc Emergency department adherence to American Heart Association guidelines for blood pressure management in acute ischemic stroke
    Erin McDonough Grise
    Departments of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Stroke 43:557-9. 2012
    ..We hypothesized that patients with AIS often receive antihypertensives in the emergency department below the recommended threshold and that BP reduction is often >20%...
  35. doi request reprint Blood pressure control for acute ischemic and hemorrhagic stroke
    Erin M Grise
    Department of Emergency Medicine and Division of Neurocritical Care, Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
    Curr Opin Crit Care 18:132-8. 2012
    ..In each case, there are theoretical dangers to leaving BP alone as well as altering it artificially. In this article, we review the role of BP in each stroke subtype and the existing evidence for BP optimization...
  36. ncbi request reprint Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage
    Edward C Jauch
    Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0769, USA
    Stroke 37:2061-5. 2006
    ..We hypothesized that hemodynamic parameters are associated with the increase in hematoma volume owing to their relationship to blood vessel wall stresses...
  37. ncbi request reprint A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection
    Phanichand Kodali
    Department of Chemistry, University of Cincinnati, Cincinnati, OH, 45221, USA
    J Neural Transm 120:1441-5. 2013
    ..We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers. ..
  38. doi request reprint Cost-effectiveness of diagnostic strategies for evaluation of suspected subarachnoid hemorrhage in the emergency department
    Michael J Ward
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Acad Emerg Med 19:1134-44. 2012
    ..The objective was to determine the relative cost-effectiveness of diagnostic strategies for SAH...
  39. ncbi request reprint Detection of metals and metalloproteins in the plasma of stroke patients by mass spectrometry methods
    Phanichand Kodali
    Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA
    Metallomics 4:1077-87. 2012
    ..This pilot study demonstrates that mass spectrometry methods may be highly valuable in detecting novel stroke biomarkers in blood plasma. Expanded studies are warranted to confirm these findings...
  40. ncbi request reprint ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study
    Jonathan J Ratcliff
    Emergency Medicine and Neurocritical Care, University of Cincinnati, 231 Albert Sabin Way, PO Box 670769, Cincinnati, OH 45267 0769 Electronic address
    Am J Emerg Med 32:844-50. 2014
    ..We evaluated factors associated with emergency department triage of mTBI patients to 1 of 3 levels of care: home, inpatient floor, or intensive care unit (ICU)...
  41. pmc A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage
    Joseph J Korfhagen
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    J Neurosci Methods 213:132-7. 2013
    ..In addition, the sensor was able to detect as little as 1 mL of blood in this 1000 mL in vitro model...
  42. ncbi request reprint Multiple liquid chromatography separations and nanoESI-ion trap detection of plasma proteins in search of stroke biomarkers: A pilot study
    Phanichand Kodali
    Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA
    J Sep Sci 35:2153-61. 2012
    ..In search of these candidate biomarkers, different analytical separation techniques have been used to screen for major differences in the proteomes of patients plasma samples with proteomics for identification...
  43. doi request reprint Geographic access to US Neurocritical Care Units registered with the Neurocritical Care Society
    Michael J Ward
    Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Room 1654H ML 0769, Cincinnati, OH 45267 0769, USA
    Neurocrit Care 16:232-40. 2012
    ..In addition, we examined how mode of transportation (ground or air ambulance), and prehospital transport times affected population access to NCUs...
  44. doi request reprint NIH Roundtable on Emergency Trauma Research
    Charles B Cairns
    Department of Emergency Medicine, University of North Carolina, 170 Manning Dr, Chapel Hill, NC 27599, USA
    Ann Emerg Med 56:538-50. 2010
    ....
  45. ncbi request reprint Management of arterial hypertension in patients with acute stroke
    Opeolu Adeoye
    University of Cincinnati, Department of Emergency Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    Curr Treat Options Neurol 8:477-85. 2006
    ..Ongoing trials will improve our current knowledge regarding BP management after ischemic and hemorrhagic stroke...