Research Topics
| Opeolu AdeoyeSummaryAffiliation: University of Cincinnati Country: USA Publications
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Detail Information
Publications
Efficiency of enrollment in a successful phase II acute stroke clinical trialOpeolu Adeoye
Department of Emergency Medicine and Neurosurgery, University of Cincinnati Neuroscience Institute, Cincinnati, Ohio 45267 0525, USA
J Stroke Cerebrovasc Dis 21:667-72. 2012..We hypothesized that missed opportunities for enrollment of eligible patients occurred frequently, despite the success of the trial...
Recombinant tissue-type plasminogen activator use for ischemic stroke in the United States: a doubling of treatment rates over the course of 5 yearsOpeolu Adeoye
UC Neuroscience Institute, Department of Emergency Medicine, 231 Albert Sabin Way, ML 0769, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Stroke 42:1952-5. 2011..In 2004, 1.8% to 2.1% of AIS patients in the United States received rtPA. Given incentives from regulatory agencies and payors to increase rtPA use, we hypothesized that rtPA use in the United States would increase from 2005 to 2009...
The rate of hemicraniectomy for acute ischemic stroke is increasing in the United StatesOpeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0525, USA
J Stroke Cerebrovasc Dis 20:251-4. 2011..Publication of the landmark study did not appear to significantly change this rate. Future studies should investigate the appropriateness of patient selection and missed opportunities for treatment...
Is ED disposition associated with intracerebral hemorrhage mortality?Opeolu Adeoye
UC Neuroscience Institute, Cincinnati, OH 45267, USA
Am J Emerg Med 29:391-5. 2011..We also compared observed with expected mortality in transferred and nontransferred patients using published short-term mortality predictors for ICH...
Advances in the management of intracerebral hemorrhageOpeolu Adeoye
Department of Emergency Medicine, Division of Neurocritical Care, University of Cincinnati Medical Center, 231 Albert Sabin Way, ML 0769, Cincinnati, OH 45267 0525, USA
Nat Rev Neurol 6:593-601. 2010..In this Review, we discuss clinical trials for ICH that have been completed in the past 10 years, the contributions of these studies to the clinical management of ICH, and the ongoing trials that might further improve clinical care...
Trends in surgical management and mortality of intracerebral hemorrhage in the United States before and after the STICH trialOpeolu Adeoye
Department of Emergency Medicine, UC Neuroscience Institute, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Neurocrit Care 13:82-6. 2010..Using a national hospital database, we determined trends in surgery for ICH before and after publication of STICH. We also determined trends in ICH mortality during the study period...
Emergency medical services use by stroke patients: a population-based studyOpeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Am J Emerg Med 27:141-5. 2009..In an epidemiological study, we determined the proportion of stroke patients who used EMS, hypothesizing that demographics, stroke severity, stroke type, and location at stroke onset would be associated with EMS use...
Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005Opeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Neurosurgery 63:1113-7; discussion 1117-8. 2008..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005...
Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohortOpeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Neurocrit Care 9:237-41. 2008..We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria...
How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?Opeolu Adeoye
Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Stroke 41:2218-22. 2010..We determined how frequently MRI/DWI was performed for TIA and ascertained the proportion of clinically defined TIA patients who had ischemic lesions on DWI in our community in 2005...
The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trialArthur M Pancioli
Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
Stroke 39:3268-76. 2008....
Trends in substance abuse preceding stroke among young adults: a population-based studyFelipe de Los Ríos
University of Cincinnati College of Medicine, Department of Neurology, and Cincinnati Children s Hospital, 260 Stetson St, Suite 2300, Cincinnati, OH 45267, USA
Stroke 43:3179-83. 2012..Approximately 5% of strokes occur in adults aged 18 to 44 years. Substance abuse is a prevalent risk factor for stroke in young adults. We sought to identify trends in substance abuse detection among stroke patients...
Age at stroke: temporal trends in stroke incidence in a large, biracial populationBrett M Kissela
University of Cincinnati College of Medicine, Cincinnati, OH, USA
Neurology 79:1781-7. 2012..We hypothesized that stroke incidence in younger adults (age 20-54) increased over time, most notably between 1999 and 2005...
Patients living in impoverished areas have more severe ischemic strokesDawn Kleindorfer
Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Stroke 43:2055-9. 2012..However, predictors of initial stroke severity have not been well-described within a population. We hypothesized that poorer patients would have a higher initial stroke severity on presentation to medical attention...
Eligibility for Intravenous Recombinant Tissue-Type Plasminogen Activator Within a Population: The Effect of the European Cooperative Acute Stroke Study (ECASS) III TrialFelipe de Los Ríos la Rosa
Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA
Stroke 43:1591-5. 2012..5 hours from symptom onset. The impact of the expanded time window on treatment rates has not been comprehensively evaluated in a population-based study...
Ischemic stroke survivors' opinion regarding research utilizing exception from informed consentDawn Kleindorfer
University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Cerebrovasc Dis 32:321-6. 2011..We obtained ischemic stroke survivors' opinions regarding hypothetical enrollment into a clinical trial at the time of their stroke without personal or proxy consent...
How often are patients with ischemic stroke eligible for decompressive hemicraniectomy?Ralph Rahme
Department of Neurosurgery, University of Cincinnati, Cincinnati, OH 45267, USA
Stroke 43:550-2. 2012....
Which stroke symptoms prompt a 911 call? A population-based studyDawn Kleindorfer
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
Am J Emerg Med 28:607-12. 2010..Most studies have found that less than half of stroke/transient ischemic attack (TIA) events result in a 911 call. We sought to determine which symptoms prompt the public to call 911...
Withdrawal of antithrombotic agents and its impact on ischemic stroke occurrenceJoseph P Broderick
University of Cincinnati, Department of Neurology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center MSB 0525, Cincinnati, OH 45242, USA
Stroke 42:2509-14. 2011..These medications are also stopped by patients for various reasons such as cost, side effects, or unwillingness to take medication...
The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Stroke 40:1738-42. 2009..We determined the number of patients that would be eligible for enrollment in hypothetical treatment trials for WICH using a population-based study...
Carotid artery stenosis as a cause of strokeMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Neuroepidemiology 40:36-41. 2013..We determined the types of large-vessel atherosclerosis responsible for ischemic strokes in a population-based stroke study...
Comparison of two depression measures for predicting stroke outcomesLawson Wulsin
University of Cincinnati, Department of Psychiatry, Cincinnati, OH 45267 0559, United States
J Psychosom Res 72:175-9. 2012..This study compared a measure of current symptoms of depression at the time of the stroke and a measure of lifetime history of depression for their ability to predict quality of life and functioning at 3 and 12 months after stroke...
US geographic distribution of rt-PA utilization by hospital for acute ischemic strokeDawn Kleindorfer
Department of Neurology, University of Cincinnati, Ohio 45267 0525, USA
Stroke 40:3580-4. 2009..We describe the US geographic distribution of hospitals using rt-PA for acute ischemic stroke...
Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke StudyDawn O Kleindorfer
Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45242, USA
Stroke 41:1326-31. 2010..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005...
The practice of carotid revascularization in a large metropolitan populationMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
J Stroke Cerebrovasc Dis 22:143-8. 2013..Point estimates for perioperative risk after CEA were improved from previous studies but remained above the recommended benchmarks. The number of CAS procedures was low, but the perioperative risk was significant...
Emergency department adherence to American Heart Association guidelines for blood pressure management in acute ischemic strokeErin McDonough Grise
Departments of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
Stroke 43:557-9. 2012..We hypothesized that patients with AIS often receive antihypertensives in the emergency department below the recommended threshold and that BP reduction is often >20%...
Blood pressure control for acute ischemic and hemorrhagic strokeErin M Grise
Department of Emergency Medicine and Division of Neurocritical Care, Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
Curr Opin Crit Care 18:132-8. 2012..In each case, there are theoretical dangers to leaving BP alone as well as altering it artificially. In this article, we review the role of BP in each stroke subtype and the existing evidence for BP optimization...
Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhageEdward C Jauch
Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0769, USA
Stroke 37:2061-5. 2006..We hypothesized that hemodynamic parameters are associated with the increase in hematoma volume owing to their relationship to blood vessel wall stresses...
Cost-effectiveness of diagnostic strategies for evaluation of suspected subarachnoid hemorrhage in the emergency departmentMichael J Ward
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Acad Emerg Med 19:1134-44. 2012..The objective was to determine the relative cost-effectiveness of diagnostic strategies for SAH...
Detection of metals and metalloproteins in the plasma of stroke patients by mass spectrometry methodsPhanichand Kodali
Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA
Metallomics 4:1077-87. 2012..This pilot study demonstrates that mass spectrometry methods may be highly valuable in detecting novel stroke biomarkers in blood plasma. Expanded studies are warranted to confirm these findings...
Multiple liquid chromatography separations and nanoESI-ion trap detection of plasma proteins in search of stroke biomarkers: A pilot studyPhanichand Kodali
Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA
J Sep Sci 35:2153-61. 2012..In search of these candidate biomarkers, different analytical separation techniques have been used to screen for major differences in the proteomes of patients plasma samples with proteomics for identification...
Geographic access to US Neurocritical Care Units registered with the Neurocritical Care SocietyMichael J Ward
Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Room 1654H ML 0769, Cincinnati, OH 45267 0769, USA
Neurocrit Care 16:232-40. 2012..In addition, we examined how mode of transportation (ground or air ambulance), and prehospital transport times affected population access to NCUs...
Management of arterial hypertension in patients with acute strokeOpeolu Adeoye
University of Cincinnati, Department of Emergency Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Curr Treat Options Neurol 8:477-85. 2006..Ongoing trials will improve our current knowledge regarding BP management after ischemic and hemorrhagic stroke...
NIH Roundtable on Emergency Trauma ResearchCharles B Cairns
Department of Emergency Medicine, University of North Carolina, 170 Manning Dr, Chapel Hill, NC 27599, USA
Ann Emerg Med 56:538-50. 2010....
