Russell C Addis

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Induced regeneration--the progress and promise of direct reprogramming for heart repair
    Russell C Addis
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine and Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Nat Med 19:829-36. 2013
  2. pmc Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success
    Russell C Addis
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Mol Cell Cardiol 60:97-106. 2013
  3. pmc Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector
    Russell C Addis
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e28719. 2011
  4. ncbi Optimal isolation and xeno-free culture conditions for limbal stem cell function
    Kalliopi Stasi
    the Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Invest Ophthalmol Vis Sci 55:375-86. 2014
  5. ncbi Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes
    Jamie L Ifkovits
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e89678. 2014
  6. doi OCT3/4 regulates transcription of histone deacetylase 4 (Hdac4) in mouse embryonic stem cells
    Russell C Addis
    Department of Cell and Developmental Biology, and Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Cell Biochem 111:391-401. 2010

Collaborators

  • Nicolas Christoforou
  • John D Gearhart
  • Kalliopi Stasi
  • Jamie L Ifkovits
  • Lindsay Herman
  • Davida Goings
  • Jiayan Huang
  • Giacomina Massaro-Giordano
  • Jonathan A Epstein
  • Dahlia Klein
  • Filipa Pinto

Detail Information

Publications6

  1. pmc Induced regeneration--the progress and promise of direct reprogramming for heart repair
    Russell C Addis
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine and Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Nat Med 19:829-36. 2013
    ..We also address controversies and hurdles that challenge the field. ..
  2. pmc Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success
    Russell C Addis
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Mol Cell Cardiol 60:97-106. 2013
    ..Using this stringent outcome measure, we conclude that HNGMT produces iCMs more efficiently than previously published methods...
  3. pmc Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector
    Russell C Addis
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e28719. 2011
    ..The present study is the first demonstration that a single vector can mediate reprogramming to dopaminergic neurons, and indicates that astrocytes are an ideal starting population for the direct generation of dopaminergic neurons...
  4. ncbi Optimal isolation and xeno-free culture conditions for limbal stem cell function
    Kalliopi Stasi
    the Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Invest Ophthalmol Vis Sci 55:375-86. 2014
    ..To preserve limbal stem cell (LSC) function in vitro with xenobiotic-free culture conditions...
  5. ncbi Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes
    Jamie L Ifkovits
    Department of Cell and Developmental Biology, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e89678. 2014
    ..Incorporation of SB in the reprogramming process increases the efficiency of iCM generation, one of the major goals necessary to enable the use of iCMs for discovery-based applications and for the clinic. ..
  6. doi OCT3/4 regulates transcription of histone deacetylase 4 (Hdac4) in mouse embryonic stem cells
    Russell C Addis
    Department of Cell and Developmental Biology, and Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Cell Biochem 111:391-401. 2010
    ..HDAC4 is not expressed in the nuclei of OCT3/4+ mES cells and is upregulated upon differentiation. These findings demonstrate the participation of OCT3/4 in the repression of Hdac4 in ES cells...