Roger H Adamson

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible
    R H Adamson
    Department of Physiology and Membrane Biology, School of Medicine, University of California at Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 302:H1929-35. 2012
  2. pmc Clostridium perfringens epsilon-toxin increases permeability of single perfused microvessels of rat mesentery
    R H Adamson
    Department of Physiology and Membrane Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
    Infect Immun 73:4879-87. 2005
  3. pmc Oncotic pressures opposing filtration across non-fenestrated rat microvessels
    R H Adamson
    Department of Human Physiology, University of California, Davis, CA 95616, USA
    J Physiol 557:889-907. 2004
  4. pmc Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels
    Roger H Adamson
    Department of Physiology and Membrane Biology, School of Medicine, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Cardiovasc Res 88:344-51. 2010
  5. ncbi request reprint PAF- and bradykinin-induced hyperpermeability of rat venules is independent of actin-myosin contraction
    R H Adamson
    Departmentof Human Physiology, School of Medicine, University of California Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 285:H406-17. 2003
  6. doi request reprint Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery
    R H Adamson
    Physiology and Membrane Biology, School of Medicine, University of California at Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 294:H1188-96. 2008
  7. pmc Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice
    Yueh Chen Lin
    Department of Physiology and Membrane Biology, School of Medicine, 1 Shields Avenue, University of California, Davis, CA 95616, USA
    J Physiol 590:309-22. 2012
  8. pmc Phosphodiesterase 4 inhibition attenuates atrial natriuretic peptide-induced vascular hyperpermeability and loss of plasma volume
    Yueh Chen Lin
    Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA 95616, USA
    J Physiol 589:341-53. 2011
  9. pmc Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Cardiovasc Res 87:218-29. 2010
  10. ncbi request reprint cAMP protects endothelial barrier functions by preventing Rac-1 inhibition
    J Waschke
    Dept of Physiology and Membrane Biology, School of Medicine, Univ of California, 1 Shields Ave, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 287:H2427-33. 2004

Detail Information

Publications19

  1. pmc Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible
    R H Adamson
    Department of Physiology and Membrane Biology, School of Medicine, University of California at Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 302:H1929-35. 2012
    ..When S1P was removed, Rac activation returned to control within 2 min. Because of such differing time courses, S1P and cAMP are unlikely to act through fully common effector mechanisms...
  2. pmc Clostridium perfringens epsilon-toxin increases permeability of single perfused microvessels of rat mesentery
    R H Adamson
    Department of Physiology and Membrane Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
    Infect Immun 73:4879-87. 2005
    ..The results conformed to the hypothesis that epsilon-toxin interacts with vascular endothelial cells and increases the vessel wall permeability by direct damage of the endothelium...
  3. pmc Oncotic pressures opposing filtration across non-fenestrated rat microvessels
    R H Adamson
    Department of Human Physiology, University of California, Davis, CA 95616, USA
    J Physiol 557:889-907. 2004
    ....
  4. pmc Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels
    Roger H Adamson
    Department of Physiology and Membrane Biology, School of Medicine, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Cardiovasc Res 88:344-51. 2010
    ..We aimed to further investigate the mechanisms whereby S1P modulates both baseline and increased permeability in intact microvessels...
  5. ncbi request reprint PAF- and bradykinin-induced hyperpermeability of rat venules is independent of actin-myosin contraction
    R H Adamson
    Departmentof Human Physiology, School of Medicine, University of California Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 285:H406-17. 2003
    ..The results are consistent with paracellular gap formation by local release of endothelial-endothelial cell adhesion structures in the absence of contraction by the actin-myosin network...
  6. doi request reprint Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery
    R H Adamson
    Physiology and Membrane Biology, School of Medicine, University of California at Davis, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 294:H1188-96. 2008
    ..Our results indicate that increased permeability in intact microvessels by acute inflammatory agents such as PAF is the result of the decreased effectiveness of the Epac/Rap1 pathway modulation of cell-cell adhesion...
  7. pmc Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice
    Yueh Chen Lin
    Department of Physiology and Membrane Biology, School of Medicine, 1 Shields Avenue, University of California, Davis, CA 95616, USA
    J Physiol 590:309-22. 2012
    ..These observations may form the basis for new strategies to retain intravenous fluid containing macromolecules...
  8. pmc Phosphodiesterase 4 inhibition attenuates atrial natriuretic peptide-induced vascular hyperpermeability and loss of plasma volume
    Yueh Chen Lin
    Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, CA 95616, USA
    J Physiol 589:341-53. 2011
    ..Stabilizing the endothelial barrier to offset ANP-induced increases in vascular permeability may be part of a strategy to maintain plasma volume...
  9. pmc Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Cardiovasc Res 87:218-29. 2010
    ..Lastly, we review new approaches to investigation of the glycocalyx barrier properties in cultured endothelial monolayers and in whole-body investigations...
  10. ncbi request reprint cAMP protects endothelial barrier functions by preventing Rac-1 inhibition
    J Waschke
    Dept of Physiology and Membrane Biology, School of Medicine, Univ of California, 1 Shields Ave, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 287:H2427-33. 2004
    ..Our study suggests that cAMP may provide its well-established protective effects at least in part by regulation of Rho proteins...
  11. pmc Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice
    R H Adamson
    Department of Human Physiology, University of California, Davis, CA 95616, USA
    J Physiol 539:295-308. 2002
    ..Rho proteins as well as RhoA-mediated contractile mechanisms are not involved in bradykinin- or PAF-induced hyperpermeability of intact microvessels...
  12. pmc Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume
    Fitz Roy E Curry
    Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Davis, CA 95616, USA
    J Physiol 588:325-39. 2010
    ..These quantitative methods will enable further evaluation of the contribution of ANP-dependent microvascular beds (such as gastro-intestinal tract) to plasma volume regulation...
  13. ncbi request reprint Thrombin increases permeability only in venules exposed to inflammatory conditions
    F E Curry
    Department of Human Physiology, University of California, Davis, 1 Shields Ave, Davis, CA 95616, USA
    Am J Physiol Heart Circ Physiol 285:H2446-53. 2003
    ....
  14. ncbi request reprint Enhancement of vascular permeability with low-frequency contrast-enhanced ultrasound in the chorioallantoic membrane model
    Susanne M Stieger
    Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Radiology 243:112-21. 2007
    ....
  15. ncbi request reprint Regulation of actin dynamics is critical for endothelial barrier functions
    J Waschke
    Institute of Anatomy and Cell Biology, University of Wurzburg, Wurzburg, Germany
    Am J Physiol Heart Circ Physiol 288:H1296-305. 2005
    ..However, cAMP, which is known to support endothelial barrier functions, seems to work by mechanisms other than stabilizing F-actin...
  16. ncbi request reprint Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro
    J Waschke
    Institute of Anatomy and Cell Biology, University of Wurzburg, Wurzburg, Germany
    Am J Physiol Heart Circ Physiol 287:H704-11. 2004
    ....
  17. ncbi request reprint Requirement of Rac activity for maintenance of capillary endothelial barrier properties
    J Waschke
    Institute of Anatomy and Cell Biology, Julius Maximilians Univ, Koellikerstrasse 6, D 97070 Wurzburg, Germany
    Am J Physiol Heart Circ Physiol 286:H394-401. 2004
    ..We conclude that Rac regulates endothelial barrier properties in vivo and in vitro by 1) modulation of actin filament polymerization and 2) acting directly on the tether between VE-cadherin and the cytoskeleton...
  18. pmc Transient regulation of transport by pericytes in venular microvessels via trapped microdomains
    X Zhang
    The Leni and Peter W May Department of Orthopaedics, Mount Sinai School of Medicine, New York, NY 10029, USA
    Proc Natl Acad Sci U S A 105:1374-9. 2008
    ..The basic concept of a trapped microdomain can also be extended to microdomains in the interstitial space surrounding skeletal muscle capillaries...
  19. ncbi request reprint Ang-1: Tie-ing up endothelial adhesion?
    R H Adamson
    Am J Physiol Heart Circ Physiol 290:H74-6. 2006