H P Adams

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Management of acute ischemic stroke
    E C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa, Iowa City 52242, USA
    Clin Geriatr Med 15:701-20. 1999
  2. ncbi request reprint 10 most commonly asked questions about which antiplatelet agent to prescribe
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Neurologist 9:318-22. 2003
  3. ncbi request reprint Certification in vascular neurology: a new subspecialty in the United States
    Harold P Adams
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Stroke 36:2293-5. 2005
  4. ncbi request reprint Stroke: a vascular pathology with inadequate management
    Harold P Adams
    Department of Neurology, University of Carver College of Medicine, Iowa City, Iowa, USA
    J Hypertens Suppl 21:S3-7. 2003
  5. ncbi request reprint Effective prophylaxis for deep vein thrombosis after stroke: low-dose anticoagulation rather than stockings alone: for
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Stroke 35:2911-2. 2004
  6. ncbi request reprint New strategies for prevention of ischemic stroke: the LIFE study
    Harold P Adams
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52246, USA
    Curr Neurol Neurosci Rep 3:46-51. 2003
  7. ncbi request reprint Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II)
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Stroke 39:87-99. 2008
  8. doi request reprint Treating patients with 'wake-up' stroke: the experience of the AbESTT-II trial
    Harold P Adams
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Stroke 39:3277-82. 2008
  9. ncbi request reprint Preview of a new trial of extracranial-to-intracranial arterial anastomosis: the carotid occlusion surgery study
    H P Adams
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Neurosurg Clin N Am 12:613-24, ix-x. 2001
  10. ncbi request reprint Measuring outcomes as a function of baseline severity of ischemic stroke
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Cerebrovasc Dis 18:124-9. 2004

Detail Information

Publications46

  1. ncbi request reprint Management of acute ischemic stroke
    E C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa, Iowa City 52242, USA
    Clin Geriatr Med 15:701-20. 1999
    ..The key to modern treatment is the emergent administration of tissue plasminogen activator (rtPA). Thrombocyte treatment improves outcome when it is given within 3 hours of onset of stroke to carefully selected patients...
  2. ncbi request reprint 10 most commonly asked questions about which antiplatelet agent to prescribe
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Neurologist 9:318-22. 2003
  3. ncbi request reprint Certification in vascular neurology: a new subspecialty in the United States
    Harold P Adams
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Stroke 36:2293-5. 2005
  4. ncbi request reprint Stroke: a vascular pathology with inadequate management
    Harold P Adams
    Department of Neurology, University of Carver College of Medicine, Iowa City, Iowa, USA
    J Hypertens Suppl 21:S3-7. 2003
    ..These agents could be combined with antithrombotic agents and surgical interventions to lessen the risk of stroke...
  5. ncbi request reprint Effective prophylaxis for deep vein thrombosis after stroke: low-dose anticoagulation rather than stockings alone: for
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Stroke 35:2911-2. 2004
  6. ncbi request reprint New strategies for prevention of ischemic stroke: the LIFE study
    Harold P Adams
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52246, USA
    Curr Neurol Neurosci Rep 3:46-51. 2003
    ..The Losartan Intervention For Endpoint (LIFE) reduction in hypertension study provides additional data to support the use of the ACE inhibitors to lower the risk of stroke among patients with hypertension and vascular diseases...
  7. ncbi request reprint Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II)
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Stroke 39:87-99. 2008
    ..The current phase 3 study was planned to test the relative efficacy and safety of abciximab in patients with acute ischemic stroke with planned treatment within 5 hours since symptoms onset...
  8. doi request reprint Treating patients with 'wake-up' stroke: the experience of the AbESTT-II trial
    Harold P Adams
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Stroke 39:3277-82. 2008
    ..We elected to test the safety and possible efficacy of abciximab in treatment of enrolled subjects with wake-up stroke...
  9. ncbi request reprint Preview of a new trial of extracranial-to-intracranial arterial anastomosis: the carotid occlusion surgery study
    H P Adams
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Neurosurg Clin N Am 12:613-24, ix-x. 2001
    ..Several issues that are being addressed in this new trial are described in this article...
  10. ncbi request reprint Measuring outcomes as a function of baseline severity of ischemic stroke
    Harold P Adams
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Cerebrovasc Dis 18:124-9. 2004
    ..While clinical trials are using baseline severity as an enrollment criterion or a stratified variable, adjustment of outcome measures as a function of initial impairments has not been done...
  11. ncbi request reprint Treatment of acute ischemic stroke: selecting the right treatment for the right patient
    H P Adams
    Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa, USA
    Eur Neurol 45:61-6. 2001
    ..The most important factors are the time interval from stroke, the severity of the neurological impairments, the results of the baseline brain imaging and the cause of stroke...
  12. ncbi request reprint Treating ischemic stroke as an emergency
    H P Adams
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Arch Neurol 55:457-61. 1998
    ..Thus, strategies for emergent treatment should aim at management of patients whose strokes are diagnosed and first treated by emergency treatment and primary care physicians with the collaboration of neurologists...
  13. ncbi request reprint Management of acute stroke: impact of registration studies
    Harold P Adams
    Division of Cerebrovascular Disorders, Department of Neurology, Carver College of Medicine, University of Iowa Health Care Stroke Center, University of Iowa, Iowa City, Iowa 52242, USA
    Acta Neurol Taiwan 19:153-63. 2010
    ..Taiwan is an ideal location for the development of such regional stroke programs...
  14. ncbi request reprint Antithrombotic treatment of ischemic stroke among patients with occlusion or severe stenosis of the internal carotid artery: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
    H P Adams
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Neurology 53:122-5. 1999
    ....
  15. ncbi request reprint Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
    H P Adams
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Neurology 53:126-31. 1999
    ..To compare the baseline National Institutes of Health Stroke Scale (NIHSS) score and the Trial of Org 10172 in Acute Stroke Treatment (TOAST) stroke subtype as predictors of outcomes at 7 days and 3 months after ischemic stroke...
  16. ncbi request reprint Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort
    J M Ringman
    Department of Neurology, University of California, Los Angeles, 710 Westwood Plaza, Suite 2 238, Los Angeles, CA 90095 1769, USA
    Neurology 63:468-74. 2004
    ..To delineate the frequency, course, risk factors, and neuroanatomy of hemispatial neglect in a large stroke cohort...
  17. pmc Baseline NIH stroke scale responses estimate the probability of each particular stroke subtype
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Cerebrovasc Dis 26:573-7. 2008
    ....
  18. ncbi request reprint Circadian variation in ischemic stroke subtypes
    S Chaturvedi
    Department of Neurology, Wayne State University, Detroit, Mich 48201, USA
    Stroke 30:1792-5. 1999
    ..The purpose of our study was to define the circadian patterns of symptom onset in an acute stroke trial with an established system for stroke subtype classification...
  19. ncbi request reprint Differences between anterior and posterior circulation stroke in TOAST
    R B Libman
    Department of Neurology, Long Island Jewish Medical Center, Long Island Campus, Albert Einstein College of Medicine, New Hyde Park, NY 11040, USA
    Cerebrovasc Dis 11:311-6. 2001
    ..We sought to explore differences between AC and PC stroke in the Trial of ORG 10172 in Acute Stroke Treatment (TOAST)...
  20. ncbi request reprint Hemispheric asymmetry of gaze deviation and relationship to neglect in acute stroke
    J M Ringman
    Department of Neurology, University of California, Los Angeles, CA 90095 1769, USA
    Neurology 65:1661-2. 2005
    ..There was no difference in its rate of co-occurrence with neglect between right- and nonright-handed patients...
  21. ncbi request reprint Early recovery after cerebral ischemia risk of subsequent neurological deterioration
    S Claiborne Johnston
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Ann Neurol 54:439-44. 2003
    ..7-5.2; p < 0.001). Among patients with acute cerebral ischemia, those who recover substantially within 24 hours may be at greater risk of subsequent neurological deterioration due to causes other than hemorrhage...
  22. ncbi request reprint Emergent use of anticoagulation for treatment of patients with ischemic stroke
    Harold P Adams
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Stroke 33:856-61. 2002
    ..Several clinical trials have tested the potential utility of emergent anticoagulation for acute ischemic stroke...
  23. ncbi request reprint Neurological aspects of biological and chemical terrorism: a review for neurologists
    Coleman O Martin
    Department of Neurology, University of Iowa College of Medicine, Iowa City, USA
    Arch Neurol 60:21-5. 2003
    ..Early recognition of these chemical and biological weapons is key to instituting specific therapy and preventing casualties within the health care team and the community at large...
  24. ncbi request reprint Feasibility of acute clinical trials during aerial interhospital transfer
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, 2 RCP, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52246, USA
    Stroke 37:2504-7. 2006
    ..If acute clinical research were feasible during the aerial interhospital transport, more patients might be enrolled in trials at a critical earlier stage...
  25. ncbi request reprint Pneumocephalus after air travel
    Matt B Jensen
    Department of Neurology, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Neurology 63:400-1. 2004
  26. ncbi request reprint Slow progressive acceptance of intravenous thrombolysis for patients with stroke by rural primary care physicians
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Arch Neurol 64:518-21. 2007
    ..In the rural United States, patients with stroke are usually first evaluated locally by a nonneurologist physician (NNP) before treatment is determined...
  27. doi request reprint Rural-urban differences in acute stroke management practices: a modifiable disparity
    Enrique C Leira
    Department of Neurology, 2147 RCP, University of Iowa College of Medicine, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Arch Neurol 65:887-91. 2008
    ....
  28. pmc Extending acute trials to remote populations: a pilot study during interhospital helicopter transfer
    Enrique C Leira
    Department of Neurology, Carver College of Medicine, Iowa City, Iowa, USA
    Stroke 40:895-901. 2009
    ..The purposes of this study were to evaluate the safety and acceptability of initiating acute stroke trials during early helicopter evacuation and to test an intervention to facilitate informed consent...
  29. pmc Escitalopram and enhancement of cognitive recovery following stroke
    Ricardo E Jorge
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
    Arch Gen Psychiatry 67:187-96. 2010
    ..Adjunctive restorative therapies administered during the first few months after stroke, the period with the greatest degree of spontaneous recovery, reduce the number of stroke patients with significant disability...
  30. ncbi request reprint Peripheral aneurysms of the lateral posterior choroidal artery: clinical presentation and endovascular treatment: report of two cases
    John B Weigele
    Interventional Neuroradiology Service, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1077, USA
    Neurosurgery 50:392-5; discussion 395-6. 2002
    ..To describe the clinical presentation and endovascular management of peripheral aneurysms of the lateral posterior choroidal artery. Aneurysms in this location are exceptionally rare and optimal treatment may be difficult...
  31. ncbi request reprint Can we predict early recurrence in acute stroke?
    Enrique C Leira
    Division of Cerebrovascular Diseases, Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Cerebrovasc Dis 18:139-44. 2004
    ..The ability to predict which patients are at risk for early recurrence would be useful for both the management and design of clinical trials...
  32. ncbi request reprint Hemiplegic migraine induced by exertion
    M Razavi
    Department of Neurology, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Arch Neurol 57:1363-5. 2000
    ..It is known that exertion can aggravate migraine headache. However, the relationship between exertion and migraine aura is unknown...
  33. doi request reprint Education Research: The challenge of incorporating formal research methodology training in a neurology residency
    E C Leira
    Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Neurology 70:e79-84. 2008
    ....
  34. ncbi request reprint Vascular neurology: a new neurologic subspecialty
    Harold P Adams
    Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    Neurology 63:774-6. 2004
    ....
  35. ncbi request reprint Spontaneous improvement after acute ischemic stroke. A pilot study
    J Biller
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242
    Stroke 21:1008-12. 1990
    ..Our results suggest that spontaneous, often dramatic improvement occurs in patients with acute ischemic stroke and should be taken into consideration in the design of any trial of acute treatment...
  36. doi request reprint Use of antiplatelet agents for prevention of ischemic stroke
    R Charles Callison
    Division of Cerebrovascular Diseases Department of Neurology, Carver College of Medicine University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Neurol Clin 26:1047-77, ix. 2008
    ..This article discusses antithrombotic treatment for ischemic stroke prevention, placing major emphasis on the indications for and administration of antiplatelet therapy...
  37. pmc Secondary prevention of atherothrombotic events after ischemic stroke
    Harold P Adams
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Mayo Clin Proc 84:43-51. 2009
    ..Nevertheless, administration of antiplatelet agents remains the core of management for preventing recurrent stroke and other cardiovascular events in at-risk patients...
  38. ncbi request reprint Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atheros
    Harold P Adams
    University of Iowa Carver College of Medicine, USA
    Circulation 115:e478-534. 2007
    ..The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included...
  39. ncbi request reprint Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atheros
    Harold P Adams
    Stroke 38:1655-711. 2007
    ..The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included...
  40. ncbi request reprint The Carotid Occlusion Surgery Study
    Robert L Grubb
    Department of Neurological Surgery, Washington University School of Medicine, Washington University Medical Center, St Louis, Missouri 63110 1093, USA
    Neurosurg Focus 14:e9. 2003
    ..It is estimated that 186 patients will be required in each group. Assuming that 40% of PET scans will demonstrate increased OEF, this will require enrolling 930 clinically eligible individuals...
  41. ncbi request reprint Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association
    Harold P Adams
    Stroke 34:1056-83. 2003
  42. ncbi request reprint Clinical implications of PROGRESS: questions and answers
    John Chalmers
    Institute for International Health, University of Sydney, Newtown, NSW, Australia
    J Hypertens Suppl 21:S21-4. 2003
  43. ncbi request reprint Patent foramen ovale: paradoxical embolism and paradoxical data
    Harold P Adams
    Mayo Clin Proc 79:15-20. 2004
  44. doi request reprint Vascular neurology: a new neurologic subspecialty in the United States
    Harold P Adams
    Int J Stroke 1:41-2. 2006
  45. ncbi request reprint Lessons from adult stroke trials
    Steven G Pavlakis
    Mount Sinai School of Medicine, New York, New York, USA
    Pediatr Neurol 34:446-9. 2006
    ..Because clinical trials, more often than not, fail to give positive (effective treatment) results, it seems reasonable to attempt to learn from others' past experiences before initiating pediatric stroke trials...
  46. ncbi request reprint Perspectives in the management of acute stroke
    Harold P Adams
    Ital Heart J 4:291-4. 2003