Research Topics
| Gregory AdamsSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Voluntary exercise during chronic renal failure in ratsGregory R Adams
Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697 4560, USA
Med Sci Sports Exerc 37:557-62. 2005..An additional objective was to examine physiological parameters related to skeletal muscle and cardiovascular adaptation in the context of CRF and exercise...- Insulin-like growth factor I signaling in skeletal muscle and the potential for cytokine interactionsGregory R Adams
Department of Physiology and Biophysics, University of California, Irvine, CA 92697 4560, USA
Med Sci Sports Exerc 42:50-7. 2010..This presentation and the ensuing brief review are intended to present a selection of the potential interactions between these two critical processes... - Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent durationGregory R Adams
Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697 4560, USA
J Appl Physiol 96:1613-8. 2004..These results indicate that relatively pure movement mode exercises result in similar levels of compensatory hypertrophy that do not necessarily track with the total amount of force generated during each contraction... - Skeletal muscle unweighting: spaceflight and ground-based modelsGregory R Adams
Department of Physiology and Biophysics, University of California, Irvine, CA 92697 4560, USA
J Appl Physiol 95:2185-201. 2003.... - Skeletal muscle dysfunction in chronic renal failure: effects of exerciseGregory R Adams
Department of Physiology and Biophysics, University of California, Irvine 92697 4560, USA
Am J Physiol Renal Physiol 290:F753-61. 2006.... - Satellite cell proliferation and skeletal muscle hypertrophyGregory R Adams
Department of Physiology and Biophysics, Medical Science I D335, University of California, Irvine, CA 92697, USA
Appl Physiol Nutr Metab 31:782-90. 2006..Recent evidence suggests that a potential limitation to muscle hypertrophy, in the absence of a reserve supply of myonuclei, may be the inability to sustain increases in ribosomes, thereby limiting translational capacity... - Cellular and molecular responses to increased skeletal muscle loading after irradiationGregory R Adams
Department of Physiology and Biophysics, Medical Sciences IC308, College of Medicine, University of California, Irvine, CA 92697, USA
Am J Physiol Cell Physiol 283:C1182-95. 2002..Thus it appears that stem cells were not added to the irradiated muscles in this time period. These data are consistent with the theory that the addition of new myonuclei may be required for compensatory hypertrophy in the rat... - Invited Review: Autocrine/paracrine IGF-I and skeletal muscle adaptationGregory R Adams
Department of Physiology and Biophysics, University of California, Irvine, California 92697, USA
J Appl Physiol 93:1159-67. 2002..In addition, a number of recent findings are presented that highlight the potential for interactions between IGF-I-related signaling pathways and intracellular signaling mechanisms activated by cytokines or hormonal systems... - Selected contribution: acute cellular and molecular responses to resistance exerciseFadia Haddad
Department of Physiology and Biophysics, University of California, Irvine 92697, USA
J Appl Physiol 93:394-403. 2002..These methods could also be used to compare and contrast different exercise parameters (e.g., concentric vs. eccentric, etc.)... - Inhibition of MAP/ERK kinase prevents IGF-I-induced hypertrophy in rat musclesFadia Haddad
Department of Physiology and Biophysics, University of California, Irvine, CA 92697-4560, USA
J Appl Physiol 96:203-10. 2004..001 vs. 3-fold, P < 0.01). These results suggest that there are interactions between the various pathways down stream of the IGF-I receptor that may behave differently in vivo than in myogenic cell lines in vitro... - Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophyFadia Haddad
Department of Physiology and Biophysics, University of California, Irvine, Medical Sciences 1, Rm D335, 92697 4560, USA
J Appl Physiol 100:1188-203. 2006..The results of this study indicate that a number of components of intracellular signaling pathways are sensitive to age. As a result, key anticatabolic responses appear to be refractory to the stimuli provided by RE... - Effect of exercise training on aortic tone in chronic renal insufficiencyStan Shelkovnikov
Department of Pharmacology, University of California Irvine, Irvine, California, USA
Am J Hypertens 21:564-9. 2008..This study was designed to test the effect of regular exercise on vasodilatory and vasoconstrictive responses of the thoracic aorta in rats with renal mass reduction... - A rat model of exercise-induced asthma: a nonspecific response to a specific immunogenEinat Kodesh
Department of Pediatrics, University of California, Irvine, Irvine, California 92697 4560, USA
Am J Physiol Regul Integr Comp Physiol 300:R917-24. 2011..Precisely how this immune crossover occurs is not known, but this model may be useful in elucidating essential mechanisms of EIB... - Time course of molecular responses of human skeletal muscle to acute bouts of resistance exerciseC Scott Bickel
Department of Physical Therapy, Louisiana State University, New Orleans, Louisiana, USA
J Appl Physiol 98:482-8. 2005..This approach should provide insights on the mechanisms that modulate adaptation to RE and may be useful in evaluating RE training protocol variables with high temporal resolution... - Effects of microgravity on myogenic factor expressions during postnatal development of rat skeletal muscleManabu Inobe
Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187 8502, Japan
J Appl Physiol 92:1936-42. 2002..In contrast, MRF4 expression was not changed in any muscle. These results suggest that MyoD and myogenin, but not MRF4, are sensitive to gravity-related stimuli in some skeletal muscles during postnatal development... - Acute molecular responses of skeletal muscle to resistance exercise in able-bodied and spinal cord-injured subjectsC Scott Bickel
Department of Exercise Science, University of Georgia, Athens, Georgia 30602, USA
J Appl Physiol 94:2255-62. 2003..The responses seen in the SCI muscles indicate that the systems that regulate these molecular responses are intact, even after extended periods of muscle unloading... - Gender differences in resistance-training-induced myofiber hypertrophy among older adultsMarcas M Bamman
Geriatric Research, Education, and Clinical Center, VA Medical Center, Birmingham, Alabama, USA
J Gerontol A Biol Sci Med Sci 58:108-16. 2003..05). In summary, gender differences in load-induced myofiber hypertrophy among older adults cannot be explained by levels of circulating IGF-1 or dehydroepiandrosterone sulfate, or by expression of the myogenic transcripts examined... - Human unilateral lower limb suspension as a model for spaceflight effects on skeletal muscleGregory R Adams
Marquette U, Milwaukee, WI
J Appl Physiol 93:1563-5; author reply 1565-6. 2002 - Isolation and characterization of a novel gene sfig in rat skeletal muscle up-regulated by spaceflight (STS-90)Mihoko Kano
U CA, Irwine
J Med Invest 50:39-47. 2003..These results suggest that spaceflight has many genetic effects on rat skeletal muscle... - Skeletal muscle gene expression in space-flown ratsTakeshi Nikawa
Department of Nutrition, The University of Tokushima School of Medicine, 3 18 15 Kuramoto cho, Tokushima 770 8503, Japan
FASEB J 18:522-4. 2004....
Research Grants
- SATELLITE CELLS AND MUSCLE HYPERTROPHY: ROLE OF IGF-IGregory Adams; Fiscal Year: 2003..The proposed experiments will elucidate the role of the IGF-1 signaling system in the hypertrophy process. ..