ERIN JUNE ADAMS

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Nat Immunol 9:777-84. 2008
  2. pmc The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor
    Jacinto López-Sagaseta
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America
    PLoS Biol 10:e1001412. 2012
  3. doi request reprint Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, 929 East 57th Street, GCIS W236, Chicago, IL 60637, United States Electronic address
    Curr Opin Immunol 26:1-6. 2014
  4. doi request reprint The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Annu Rev Immunol 31:529-61. 2013
  5. pmc Diverse antigen presentation by the Group 1 CD1 molecule, CD1c
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, United States
    Mol Immunol 55:182-5. 2013
  6. ncbi request reprint The immutable recognition of CD1d
    Erin J Adams
    Department of Biochemistry and Molecular Biology, Committee on Immunology, University of Chicago, Chicago, IL 60637, USA
    Immunity 34:281-3. 2011
  7. pmc Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors
    Erin J Adams
    Departments of Molecular and Cellular Physiology and Structural Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:10128-33. 2007
  8. ncbi request reprint Antigen recognition determinants of gammadelta T cell receptors
    Sunny Shin
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 308:252-5. 2005
  9. ncbi request reprint Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22
    Erin J Adams
    Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild D319, 299 Campus Drive, Stanford, CA 94035 5124, USA
    Science 308:227-31. 2005
  10. ncbi request reprint Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
    Michelle Krogsgaard
    Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Cell 12:1367-78. 2003

Collaborators

Detail Information

Publications12

  1. pmc An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Nat Immunol 9:777-84. 2008
    ..Our results demonstrate unprecedented autonomy of a single CDR3 loop in antigen recognition...
  2. pmc The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor
    Jacinto López-Sagaseta
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America
    PLoS Biol 10:e1001412. 2012
    ..These data illustrate how fine specificity for a lipid containing α-linked galactose is achieved by a TCR structurally distinct from that of iNKT cells...
  3. doi request reprint Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, 929 East 57th Street, GCIS W236, Chicago, IL 60637, United States Electronic address
    Curr Opin Immunol 26:1-6. 2014
    ..Here I review recent advances in Group 1 CD1 lipid presentation, the T cell populations that respond to them and the role of CD1 molecules in engagement of human γδ T cells. ..
  4. doi request reprint The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Annu Rev Immunol 31:529-61. 2013
    ..The variations on the theme of a β-sheet topped by two semiparallel α-helices are discussed in this review, highlighting the fantastic adaptability of this fold for good and for bad...
  5. pmc Diverse antigen presentation by the Group 1 CD1 molecule, CD1c
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, United States
    Mol Immunol 55:182-5. 2013
    ....
  6. ncbi request reprint The immutable recognition of CD1d
    Erin J Adams
    Department of Biochemistry and Molecular Biology, Committee on Immunology, University of Chicago, Chicago, IL 60637, USA
    Immunity 34:281-3. 2011
    ..CD1d presents lipid antigens to natural killer T cells. In this issue of Immunity, Wun et al. (2011) and Mallevaey et al. (2011) explore the molecular details of nonself lipid discrimination and self-recognition...
  7. pmc Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors
    Erin J Adams
    Departments of Molecular and Cellular Physiology and Structural Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:10128-33. 2007
    ..Collectively, our results show that m157 represents a structurally divergent form of MHC class I-like proteins that directly engage Ly49 receptors with appreciable affinity in a noncanonical fashion...
  8. ncbi request reprint Antigen recognition determinants of gammadelta T cell receptors
    Sunny Shin
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 308:252-5. 2005
    ..These results show how an antigen-specific gammadelta TCR repertoire can be generated at a high frequency and suggest that gammadelta T cells recognize a limited number of antigens...
  9. ncbi request reprint Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22
    Erin J Adams
    Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild D319, 299 Campus Drive, Stanford, CA 94035 5124, USA
    Science 308:227-31. 2005
    ..That junctionally encoded G8 residues play an ancillary role in binding suggests a fusion of innate and adaptive recognition strategies...
  10. ncbi request reprint Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
    Michelle Krogsgaard
    Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Cell 12:1367-78. 2003
    ..Structural analysis shows significant changes in the central TCR contact residue of the peptide-MHC, indicating that structural rearrangements within the TCR-peptide-MHC interface can contribute to T cell activation...
  11. ncbi request reprint NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C
    Lisbeth A Guethlein
    Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305 5126, USA
    J Immunol 169:220-9. 2002
    ..The Popy-KIR2D include ones predicted to be specific for the C1 epitope of MHC-C, but none specific for C2. This correlates with the observation that all orangutan MHC-C allotypes examined have the C1 motif...
  12. ncbi request reprint Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes)
    Ron Geller
    Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305 5126, USA
    Immunogenetics 54:212-5. 2002
    ..The results demonstrate that Patr-AL is an MHC class I gene present on different MHC haplotypes as defined by their combination of Patr-A and B alleles...