ERIN JUNE ADAMS

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Nat Immunol 9:777-84. 2008
  2. pmc Human gamma delta T cells: Evolution and ligand recognition
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA Committee on Immunology, University of Chicago, Chicago, IL 60637, USA Committee on Cancer Biology, University of Chicago, Chicago, IL 60637, USA Electronic address
    Cell Immunol 296:31-40. 2015
  3. pmc The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor
    Jacinto López-Sagaseta
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America
    PLoS Biol 10:e1001412. 2012
  4. pmc Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, 929 East 57th Street, GCIS W236, Chicago, IL 60637, United States Electronic address
    Curr Opin Immunol 26:1-6. 2014
  5. doi request reprint The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Annu Rev Immunol 31:529-61. 2013
  6. pmc Diverse antigen presentation by the Group 1 CD1 molecule, CD1c
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, United States
    Mol Immunol 55:182-5. 2013
  7. ncbi request reprint The immutable recognition of CD1d
    Erin J Adams
    Department of Biochemistry and Molecular Biology, Committee on Immunology, University of Chicago, Chicago, IL 60637, USA
    Immunity 34:281-3. 2011
  8. pmc Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors
    Erin J Adams
    Departments of Molecular and Cellular Physiology and Structural Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:10128-33. 2007
  9. ncbi request reprint Antigen recognition determinants of gammadelta T cell receptors
    Sunny Shin
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 308:252-5. 2005
  10. ncbi request reprint Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22
    Erin J Adams
    Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild D319, 299 Campus Drive, Stanford, CA 94035 5124, USA
    Science 308:227-31. 2005

Collaborators

Detail Information

Publications13

  1. pmc An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Nat Immunol 9:777-84. 2008
    ..Our results demonstrate unprecedented autonomy of a single CDR3 loop in antigen recognition...
  2. pmc Human gamma delta T cells: Evolution and ligand recognition
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA Committee on Immunology, University of Chicago, Chicago, IL 60637, USA Committee on Cancer Biology, University of Chicago, Chicago, IL 60637, USA Electronic address
    Cell Immunol 296:31-40. 2015
    ..From this comparison, it is clear that co-evolution between γδ TCRs and these ligands is likely occurring, but the diversity inherent in these recombined receptors is an important feature in ligand surveillance. ..
  3. pmc The molecular basis for recognition of CD1d/α-galactosylceramide by a human non-Vα24 T cell receptor
    Jacinto López-Sagaseta
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America
    PLoS Biol 10:e1001412. 2012
    ..These data illustrate how fine specificity for a lipid containing α-linked galactose is achieved by a TCR structurally distinct from that of iNKT cells...
  4. pmc Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, 929 East 57th Street, GCIS W236, Chicago, IL 60637, United States Electronic address
    Curr Opin Immunol 26:1-6. 2014
    ..Here I review recent advances in Group 1 CD1 lipid presentation, the T cell populations that respond to them and the role of CD1 molecules in engagement of human γδ T cells. ..
  5. doi request reprint The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA
    Annu Rev Immunol 31:529-61. 2013
    ..The variations on the theme of a β-sheet topped by two semiparallel α-helices are discussed in this review, highlighting the fantastic adaptability of this fold for good and for bad...
  6. pmc Diverse antigen presentation by the Group 1 CD1 molecule, CD1c
    Erin J Adams
    Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, United States
    Mol Immunol 55:182-5. 2013
    ....
  7. ncbi request reprint The immutable recognition of CD1d
    Erin J Adams
    Department of Biochemistry and Molecular Biology, Committee on Immunology, University of Chicago, Chicago, IL 60637, USA
    Immunity 34:281-3. 2011
    ..CD1d presents lipid antigens to natural killer T cells. In this issue of Immunity, Wun et al. (2011) and Mallevaey et al. (2011) explore the molecular details of nonself lipid discrimination and self-recognition...
  8. pmc Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors
    Erin J Adams
    Departments of Molecular and Cellular Physiology and Structural Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 104:10128-33. 2007
    ..Collectively, our results show that m157 represents a structurally divergent form of MHC class I-like proteins that directly engage Ly49 receptors with appreciable affinity in a noncanonical fashion...
  9. ncbi request reprint Antigen recognition determinants of gammadelta T cell receptors
    Sunny Shin
    Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 308:252-5. 2005
    ..These results show how an antigen-specific gammadelta TCR repertoire can be generated at a high frequency and suggest that gammadelta T cells recognize a limited number of antigens...
  10. ncbi request reprint Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22
    Erin J Adams
    Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild D319, 299 Campus Drive, Stanford, CA 94035 5124, USA
    Science 308:227-31. 2005
    ..That junctionally encoded G8 residues play an ancillary role in binding suggests a fusion of innate and adaptive recognition strategies...
  11. ncbi request reprint Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
    Michelle Krogsgaard
    Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA
    Mol Cell 12:1367-78. 2003
    ..Structural analysis shows significant changes in the central TCR contact residue of the peptide-MHC, indicating that structural rearrangements within the TCR-peptide-MHC interface can contribute to T cell activation...
  12. ncbi request reprint NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C
    Lisbeth A Guethlein
    Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305 5126, USA
    J Immunol 169:220-9. 2002
    ..The Popy-KIR2D include ones predicted to be specific for the C1 epitope of MHC-C, but none specific for C2. This correlates with the observation that all orangutan MHC-C allotypes examined have the C1 motif...
  13. ncbi request reprint Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes)
    Ron Geller
    Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305 5126, USA
    Immunogenetics 54:212-5. 2002
    ..The results demonstrate that Patr-AL is an MHC class I gene present on different MHC haplotypes as defined by their combination of Patr-A and B alleles...