Frank L Acosta

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    Neurosurg Focus 17:E2. 2004
  2. ncbi Frameless stereotactic image-guided C1-C2 transarticular screw fixation for atlantoaxial instability: review of 20 patients
    Frank L Acosta
    Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    J Spinal Disord Tech 18:385-91. 2005
  3. ncbi Neurocutaneous melanosis presenting with hydrocephalus. Case report and review of the literature
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 102:96-100. 2005
  4. ncbi The potential role of mesenchymal stem cell therapy for intervertebral disc degeneration: a critical overview
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 19:E4. 2005
  5. pmc Successful outcome of six-level cervicothoracic corpectomy and circumferential reconstruction: case report and review of literature on multilevel cervicothoracic corpectomy
    Frank L Acosta
    Department of Neurological Surgery, University of California, 505 Parnassus Avenue, Moffitt Hospital M779, Box 0112, San Francisco, CA 94143, USA
    Eur Spine J 15:670-4. 2006
  6. ncbi Operative management of adult high-grade lumbosacral spondylolisthesis
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 18:249-54. 2007
  7. ncbi Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cages
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
    J Spinal Disord Tech 21:165-74. 2008
  8. doi Perioperative complications and clinical outcomes of multilevel circumferential lumbar spinal fusion in the elderly
    Frank L Acosta
    Department of Neurological Surgery, University of California San Francisco, 513 Parnassus Avenue, S 225, San Francisco, CA 94143, USA
    J Clin Neurosci 16:69-73. 2009
  9. ncbi Current treatment strategies and outcomes in the management of symptomatic vertebral hemangiomas
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco 94143 0112, USA
    Neurosurgery 58:287-95; discussion 287-95. 2006
  10. ncbi Bioabsorbable anterior cervical plating: initial multicenter clinical and radiographic experience
    Henry E Aryan
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    Spine (Phila Pa 1976) 32:1084-8. 2007

Research Grants

Detail Information

Publications45

  1. ncbi Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    Neurosurg Focus 17:E2. 2004
    ....
  2. ncbi Frameless stereotactic image-guided C1-C2 transarticular screw fixation for atlantoaxial instability: review of 20 patients
    Frank L Acosta
    Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
    J Spinal Disord Tech 18:385-91. 2005
    ..We retrospectively studied 20 adults who underwent C1-C2 transarticular screw (TAS) fixation utilizing frameless stereotaxy...
  3. ncbi Neurocutaneous melanosis presenting with hydrocephalus. Case report and review of the literature
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 102:96-100. 2005
    ..Our case illustrates to the neurosurgeon the importance of recognizing the likelihood of underlying pathological conditions of the central nervous system in a child with cutaneous melanocytic nevi...
  4. ncbi The potential role of mesenchymal stem cell therapy for intervertebral disc degeneration: a critical overview
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 19:E4. 2005
    ..Although important obstacles to the survival and proliferation of stem cells within the degenerating disc need to be overcome, the potential for MSC therapy to slow or reverse the degenerative process remains substantial...
  5. pmc Successful outcome of six-level cervicothoracic corpectomy and circumferential reconstruction: case report and review of literature on multilevel cervicothoracic corpectomy
    Frank L Acosta
    Department of Neurological Surgery, University of California, 505 Parnassus Avenue, Moffitt Hospital M779, Box 0112, San Francisco, CA 94143, USA
    Eur Spine J 15:670-4. 2006
    ..To the authors' knowledge, this is the first report of a corpectomy extending across six levels of the cervico-thoracic spine...
  6. ncbi Operative management of adult high-grade lumbosacral spondylolisthesis
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 18:249-54. 2007
    ..Posterolateral pedicle screw-rod fixation has improved rates of arthrodesis compared with traditional in situ fusions. Nevertheless, complications with operative management of high-grade spondylolisthesis can be severe...
  7. ncbi Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cages
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
    J Spinal Disord Tech 21:165-74. 2008
    ..Retrospective review of clinical case series...
  8. doi Perioperative complications and clinical outcomes of multilevel circumferential lumbar spinal fusion in the elderly
    Frank L Acosta
    Department of Neurological Surgery, University of California San Francisco, 513 Parnassus Avenue, S 225, San Francisco, CA 94143, USA
    J Clin Neurosci 16:69-73. 2009
    ..Perioperative events, intermediate-term clinical outcomes, and fusion rates after multilevel 360-degree lumbar fusion in the elderly are comparable to those of younger patients...
  9. ncbi Current treatment strategies and outcomes in the management of symptomatic vertebral hemangiomas
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco 94143 0112, USA
    Neurosurgery 58:287-95; discussion 287-95. 2006
    ..Treatment included transarterial embolization, embolization followed by surgical decompression or vertebral reconstruction with arthrodesis, and percutaneous vertebroplasty alone...
  10. ncbi Bioabsorbable anterior cervical plating: initial multicenter clinical and radiographic experience
    Henry E Aryan
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    Spine (Phila Pa 1976) 32:1084-8. 2007
    ..Prospective clinical trial...
  11. ncbi Comprehensive management of symptomatic and aggressive vertebral hemangiomas
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, R505 Parnassus Avenue, Room M 779, San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 19:17-29. 2008
    ..Vertebroplasty is useful for improving pain symptoms, especially when vertebral body compression fracture has occurred in patients without neurological deficit, but is less effective in providing long-term pain relief...
  12. ncbi Modified paramedian transpedicular approach and spinal reconstruction for intradural tumors of the cervical and cervicothoracic spine: clinical experience
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, CA 94143 0112, USA
    Spine (Phila Pa 1976) 32:E203-10. 2007
    ....
  13. doi Techniques for operative correction of proximal junctional kyphosis of the upper thoracic spine
    Jamal McClendon
    Department of Neurological Surgery, Northwestern University Feinberg School of Medicine and Northwestern Memorial Hospital, 676 N St Clair Street, Chicago, IL 60611, USA
    Spine (Phila Pa 1976) 37:292-303. 2012
    ..Retrospective study of a consecutive series of patients treated for proximal junctional kyphosis (PJK) of the upper thoracic and cervicothoracic spine...
  14. ncbi Stabilization of the atlantoaxial complex via C-1 lateral mass and C-2 pedicle screw fixation in a multicenter clinical experience in 102 patients: modification of the Harms and Goel techniques
    Henry E Aryan
    Department of Neurosurgery, University of California, San Francisco Medical Center, 94143, USA
    J Neurosurg Spine 8:222-9. 2008
    ..The authors reviewed the multicenter experience with 102 patients undergoing C1-2 fusion via the polyaxial screw/rod technique. They also describe a modification to the Harms technique...
  15. ncbi Biomechanical analysis of a newly designed bioabsorbable anterior cervical plate. Invited submission from the joint section meeting on disorders of the spine and peripheral nerves, March 2005
    Christopher P Ames
    Department of Neurological Surgery, University of California at San Francisco, California 94122, USA
    J Neurosurg Spine 3:465-70. 2005
    ....
  16. doi Biomechanical comparison of three fixation techniques for unstable thoracolumbar burst fractures. Laboratory investigation
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg Spine 8:341-6. 2008
    ....
  17. ncbi Stand-alone anterior lumbar discectomy and fusion with plate: initial experience
    Henry E Aryan
    Department of Neurosurgery, University of California, San Francisco, CA 94143, USA
    Surg Neurol 68:7-13; discussion 13. 2007
    ....
  18. ncbi Patient satisfaction and radiographic outcomes after lumbar spinal fusion without iliac crest bone graft or transverse process fusion
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779, Box 0112, San Francisco, CA 94143, USA
    J Clin Neurosci 16:1184-7. 2009
    ..Patient satisfaction remained high and might be because the morbidity associated with harvesting ICBG was avoided, as was the additional muscle dissection required for the fusion of lateral transverse processes...
  19. ncbi Effects of age on perioperative complications of extensive multilevel thoracolumbar spinal fusion surgery
    Jordan M Cloyd
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg Spine 12:402-8. 2010
    ..Therefore, the purpose of this study was to analyze the effects of age in persons undergoing multilevel (> or = 5 levels) thoracolumbar fusion surgery...
  20. ncbi Partial spondylectomy: modification for lateralized malignant spinal column tumors of the cervical or lumbosacral spine
    John H Chi
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue M779, Box 0112, San Francisco, CA 94143, USA
    J Clin Neurosci 15:43-8. 2008
    ..Partial spondylectomy can be an alternative to total en bloc spondylectomy in properly selected patients with lateralized encapsulated malignant spinal tumors and may be performed in the cervical or lumbosacral spinal regions...
  21. ncbi Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis
    Henry E Aryan
    Department of Neurosurgery and UCSF Spine Center, University of California, San Francisco, California 94143 0350, USA
    J Neurosurg Spine 6:23-30. 2007
    ..The authors review their experience in performing corpectomy and fusion with titanium cages and rhBMP-2 in patients with vertebral instability and/or neurological compromise due to vertebral osteomyelitis...
  22. ncbi Biomechanical comparison of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion performed at 1 and 2 levels
    Christopher P Ames
    Department of Neurological Surgery, University of California, San Francisco, CA 94143 0112, USA
    Spine (Phila Pa 1976) 30:E562-6. 2005
    ..Biomechanical laboratory study of human cadaveric spines...
  23. ncbi The ProDisc artificial disc: insertion technique
    Henry E Aryan
    Department of Neurosurgery, University of California San Francisco, CA 94143, USA
    Neurosurg Clin N Am 16:651-6, vii. 2005
    ..The disc is implanted via an anterior approach, generally retroperitoneally but on occasion transperitoneally. The different approaches and insertion technique are described in this article...
  24. ncbi Coblation of spinal endplates in preparation for interbody spinal fusion
    Henry E Aryan
    Division of Neurosurgery, University of California, San Diego UCSD, 200 West Arbor Drive, Suite 8893, San Diego, California 92103 8893, USA
    J Clin Neurosci 13:349-52. 2006
    ..Clearly, the number of patients involved and the length of follow-up limit this study, but it serves as an early indicator that endplate preparation may play a role in graft subsidence and fusion rates. Additional study is warranted...
  25. ncbi Artificial pedicle screw reconstruction of the cervical spine after lateral paramedian transpedicular approach for lesions of the ventral cervical spinal canal
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurgery 57:281-5; discussion 281-5. 2005
    ....
  26. ncbi The Charité Artificial Disc: insertion technique
    Henry E Aryan
    Department of Neurological Surgery, University of California, San Francisco, CA 94143 0350, USA
    Neurosurg Clin N Am 16:637-50, vii. 2005
    ..With thousands of implantations worldwide since 1987, it has the longest clinical experience of any artificial disc. No other artificial disc has the substantial preclinical and clinical history that validates its use...
  27. doi Effect of age on the perioperative and radiographic complications of multilevel cervicothoracic spinal fusions
    Jordan M Cloyd
    Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
    Spine (Phila Pa 1976) 33:E977-82. 2008
    ..Retrospective review...
  28. ncbi Two-level total en bloc lumbar spondylectomy with dural resection for metastatic renal cell carcinoma
    Henry E Aryan
    Department of Neurological Surgery, University of California at San Francisco, 400 Parnassus Avenue, A868, San Francisco, CA 94143 0350, USA
    J Clin Neurosci 15:70-2. 2008
    ..We report a successful two-level spondylectomy with en bloc dural resection in a patient with metastatic renal carcinoma to the L3 and L4 vertebrae...
  29. ncbi Complications and outcomes of lumbar spine surgery in elderly people: a review of the literature
    Jordan M Cloyd
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California 94143, USA
    J Am Geriatr Soc 56:1318-27. 2008
    ..A better understanding of the risks and prognosis associated with these types of surgeries will enable more-informed decision-making by patients and physicians...
  30. ncbi Expandable cylindrical cages in the cervical spine: a review of 22 cases
    Kurtis I Auguste
    Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco School of Medicine, San Francisco, California 94143 0112, USA
    J Neurosurg Spine 4:285-91. 2006
    ..The authors present their experience with ECCs in the reconstruction of the cervical spine in patients with various pathological conditions...
  31. ncbi Biomechanics of stabilization after cervicothoracic compression-flexion injury
    Christopher P Ames
    Department of Neurological Surgery, University of California, San Francisco, CA 94143 0112, USA
    Spine (Phila Pa 1976) 30:1505-12. 2005
    ..Biomechanical laboratory research...
  32. ncbi Use of intraoperative isocentric C-arm 3D fluoroscopy for sextant percutaneous pedicle screw placement: case report and review of the literature
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M 779, San Francisco, CA 94143 0112, USA
    Spine J 5:339-43. 2005
    ..To date, however, no description is available of the intraoperative use of 3D fluoroscopy to guide lumbar pedicle screw placement in an actual spinal fusion procedure...
  33. doi Treatment of Enneking stage 3 aggressive vertebral hemangiomas with intralesional spondylectomy: report of 10 cases and review of the literature
    Frank L Acosta
    Department of Neurological Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Spinal Disord Tech 24:268-75. 2011
    ..A retrospective review of consecutive series of Enneking stage 3 vertebral hemangiomas surgically treated at a major tertiary spine tumor center...
  34. doi Morbidity and mortality after spinal deformity surgery in patients 75 years and older: complications and predictive factors
    Frank L Acosta
    Department of Neurological Surgery, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Neurosurg Spine 15:667-74. 2011
    ....
  35. ncbi En bloc resection for primary and metastatic tumors of the spine: a systematic review of the literature
    Jordan M Cloyd
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
    Neurosurgery 67:435-44; discussion 444-5. 2010
    ..The efficacy of en bloc resection for spinal tumors is unknown because most of the current evidence is provided by small, single-institution clinical series or case reports...
  36. ncbi Diagnosis and management of sacral Tarlov cysts. Case report and review of the literature
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurg Focus 15:E15. 2003
    ..They review the medical literature, describe various theories on the origin and pathogenesis of Tarlov cysts, and assess alternative treatment strategies...
  37. ncbi Emerging directions in motion preservation spinal surgery
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, Moffitt Hospital, CA 94143, USA
    Neurosurg Clin N Am 16:665-9, vii. 2005
    ..This allows for a certain degree of immobilization without fusion. Minimally invasive surgical approaches, facet arthroplasty, and posterior tension band devices may be the future of motion preservation spinal surgery...
  38. pmc Detection of postoperative granulation tissue with an ICG-enhanced integrated OI-/X-ray System
    Reinhard Meier
    Department of Radiology, University of California, San Francisco, USA
    J Transl Med 6:73. 2008
    ....
  39. ncbi Kyphoplasty-augmented short-segment pedicle screw fixation of traumatic lumbar burst fractures: initial clinical experience and literature review
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    Neurosurg Focus 18:e9. 2005
    ..In this study, the authors describe their initial clinical experience with kyphoplasty used to augment short-segment pedicle screw fixation of traumatic lumbar burst fractures...
  40. doi Cervical spine alignment, sagittal deformity, and clinical implications: a review
    Justin K Scheer
    School of Medicine, University of California, San Diego, California, USA
    J Neurosurg Spine 19:141-59. 2013
    ....
  41. pmc Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cells
    Frank L Acosta
    Orthopaedic Bioengineering Laboratory, University of California, San Francisco, CA 94143, USA
    Tissue Eng Part A 17:3045-55. 2011
    ..These data support the premise that committed chondrocytes are more appropriate for use in disc repair, as they are uniquely suited for survival in the ischemic disc microenvironment...
  42. pmc Human disc nucleus properties and vertebral endplate permeability
    Azucena G Rodriguez
    Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143, USA
    Spine (Phila Pa 1976) 36:512-20. 2011
    ..Experimental quantification of relationships between vertebral endplate morphology, permeability, disc cell density, glycosaminoglycan (GAG) content, and degeneration in samples harvested from human cadaveric spines...
  43. ncbi Cervical disc arthroplasty: general introduction
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, Moffitt Hospital, CA 94143, USA
    Neurosurg Clin N Am 16:603-7, vi. 2005
    ....
  44. ncbi Intramedullary spinal cord tumors: molecular insights and surgical innovation
    Andrew T Parsa
    Department of Neurological Surgery, University of California, San Francisco, USA
    Clin Neurosurg 52:76-84. 2005
  45. doi Changes in coronal and sagittal plane alignment following minimally invasive direct lateral interbody fusion for the treatment of degenerative lumbar disease in adults: a radiographic study
    Frank L Acosta
    Department of Neurological Surgery, Cedars Sinai Medical Center, Los Angeles 90048, USA
    J Neurosurg Spine 15:92-6. 2011
    ..The object of this study was to determine changes in sagittal and coronal plane alignment occurring after direct lateral interbody fusion (DLIF)...

Research Grants1

  1. Effect of vertebral endplate composition on disc health
    Frank Acosta; Fiscal Year: 2006
    ..We propose to determine the relationship between subchondral bone architecture, cartilaginous endplate composition and organization, and the initiation and progression of IVD degeneration in cadaveric human lumbar spines. ..