YOUSEF A ABU KWAIK

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. doi request reprint Microbial quest for food in vivo: 'nutritional virulence' as an emerging paradigm
    Yousef Abu Kwaik
    Department of Microbiology and Immunology, College of Medicine, University of Louisville, Louisville, KY 40202, USA
    Cell Microbiol 15:882-90. 2013
  2. pmc Genetic susceptibility and caspase activation in mouse and human macrophages are distinct for Legionella longbeachae and L. pneumophila
    Rexford Asare
    Department of Microbiology and Immunology, University of Louisville College of Medicine, 319 Abraham Flexner Way, Louisville, KY 40292, USA
    Infect Immun 75:1933-45. 2007
  3. pmc The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa
    Souhaila Al-Khodor
    Department of Microbiology and Immunology, College of Medicine, University of Louisville, Room 412, Louisville, KY 40202, USA
    Infect Immun 77:374-86. 2009

Research Grants

  1. Molecular pathogenesis of Francisella tularnesis
    YOUSEF A ABU KWAIK; Fiscal Year: 2010
  2. Modulation of apoptosis by Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2009
  3. Modulation of apoptosis by Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2007
  4. Molecular pathogenesis of Francisella Tularensis
    Yousef Abu Kwaik; Fiscal Year: 2007
  5. The Pore-forming Toxin of Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2003
  6. Receptor-Mediated Endocytosis of Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2004
  7. Modulation of apoptosis by Legionella Pneumophila
    YOUSEF A ABU KWAIK; Fiscal Year: 2010

Collaborators

Detail Information

Publications3

  1. doi request reprint Microbial quest for food in vivo: 'nutritional virulence' as an emerging paradigm
    Yousef Abu Kwaik
    Department of Microbiology and Immunology, College of Medicine, University of Louisville, Louisville, KY 40202, USA
    Cell Microbiol 15:882-90. 2013
    ..Host-pathogen synchronization of amino acid auxotrophy indicates that this nutritional synchronization has been a major driving force in the evolution of many intracellular bacterial pathogens...
  2. pmc Genetic susceptibility and caspase activation in mouse and human macrophages are distinct for Legionella longbeachae and L. pneumophila
    Rexford Asare
    Department of Microbiology and Immunology, University of Louisville College of Medicine, 319 Abraham Flexner Way, Louisville, KY 40292, USA
    Infect Immun 75:1933-45. 2007
    ..longbeachae does not trigger the activation of caspase 1, caspase 3, or late-stage apoptosis in mouse and human macrophages. Neither species triggers caspase 1 activation in human macrophages...
  3. pmc The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa
    Souhaila Al-Khodor
    Department of Microbiology and Immunology, College of Medicine, University of Louisville, Room 412, Louisville, KY 40202, USA
    Infect Immun 77:374-86. 2009
    ..pneumophila within human macrophages and protozoa. Differences in gene regulation and intracellular growth phenotypes between the pmrA and pmrB mutant suggests a cross talk with other TCSs...

Research Grants16

  1. Molecular pathogenesis of Francisella tularnesis
    YOUSEF A ABU KWAIK; Fiscal Year: 2010
    ..The bacterial effectors involved in exploiting the macrophage are potential targets for treatment as well as potential vaccine candidates. ..
  2. Modulation of apoptosis by Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2009
    ..The bacterial effector involved in this process is a potential target for therapy and prevention of the disease. ..
  3. Modulation of apoptosis by Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2007
    ..The bacterial effector involved in this process is a potential target for therapy and prevention of the disease. ..
  4. Molecular pathogenesis of Francisella Tularensis
    Yousef Abu Kwaik; Fiscal Year: 2007
    ..The bacterial effectors involved in exploiting the macrophage are potential targets for treatment as well as potential vaccine candidates. ..
  5. The Pore-forming Toxin of Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2003
    ..Our studies on L. pneumophila may provide a paradigm for other vacuolar intracellular pathogens such as Mycobacterium, Salmonella, and Chlamydia. ..
  6. Receptor-Mediated Endocytosis of Legionella Pneumophila
    Yousef Abu Kwaik; Fiscal Year: 2004
    ..Our studies may uncover potential pathogenic evolution of Lpn to invade the more evolved mammalian cells, and may contribute to the understanding of invasion of protozoa by Mycobacterium and Chlamydia. ..
  7. Modulation of apoptosis by Legionella Pneumophila
    YOUSEF A ABU KWAIK; Fiscal Year: 2010
    ..The bacterial effector involved in this process is a potential target for therapy and prevention of the disease. ..