MARIA TERESA ABREU
Affiliation: University of Miami
- In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancerDaniel A Sussman
Division of Gastroenterology, Department of Medicine, University of Miami, 1120 NW 14th Street, Clinical Research Building 310J, Miami, FL 33136, USA
J Exp Clin Cancer Res 33:45. 2014..To explore the relationships between TLR4 expression and CRC, we combined the strength of transcriptome array data and immunohistochemical (IHC) staining...
- TLR4 activates the β-catenin pathway to cause intestinal neoplasiaRebeca Santaolalla
Division of Gastroenterology, Department of Medicine, University of Miami, Leonard Miller School of Medicine, Miami, Florida, USA
PLoS ONE 8:e63298. 2013..Our studies highlight a previously unexplored link between innate immune signaling and activation of oncogenic pathways, which may be targeted to prevent or treat CRC...
- Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control studyInga Peter
Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY 10029 USA
BMC Med Genet 12:63. 2011..We evaluated a set of well-established CD-susceptibility variants to determine if they can explain the increased CD risk in the AJ population...
- The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasiaYasmin Hernandez
Division of Gastroenterology, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
BMC Gastroenterol 10:82. 2010....
- Extracorporeal photopheresis for the treatment of refractory Crohn's disease: results of an open-label pilot studyMaria T Abreu
University of Miami Miller School of Medicine, Miami, FL 33101 6960, USA
Inflamm Bowel Dis 15:829-36. 2009..A prospective, uncontrolled pilot study was conducted to evaluate the safety and efficacy of ECP in patients with active Crohn's disease (CD) who were refractory to or intolerant of immunosuppressants and/or anti-TNF therapies...
- Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal functionMaria T Abreu
Division of Gastroenterology, University of Miami Miller School of Medicine, P O Box 016960 D 49, Miami, Florida 33101, USA
Nat Rev Immunol 10:131-44. 2010..Thus, dysregulated TLR signalling by intestinal epithelial cells may explain how colonic bacteria and inflammation promote colorectal cancer...
- Toll-Like Receptor-Complex in Intestinal Epith. CellsMaria Abreu; Fiscal Year: 2007..The results of our studies have important implications for understanding host-microbial interactions and the inter-relationship between the innate and adaptive immune systems in the gut. ..