Research Topics
| William T AbrahamSummaryAffiliation: University of Kentucky Country: USA Publications
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Publications
Does quality of life evidence assist in the selection of patients for resynchronization therapy?Peter A McCullough
Department of Basic Science, Cardiology Section, University of Missouri Kansas City School of Medicine, Truman Medical Center, Kansas City, MO, USA
Card Electrophysiol Rev 7:71-6. 2003..In conclusion, assessment of quality of life before device implantation is necessary in order to select those individuals who are most likely to benefit from cardiac resynchronization therapy...- Predictors of remodeling in the CRT era: influence of mitral regurgitation, BNP, and genderThomas P Cappola
Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
J Card Fail 12:182-8. 2006..Future studies should take these clinical factors into account when determining the influence of genetic factors and novel therapies on ventricular remodeling in chronic heart failure... - Cardiac resynchronization in chronic heart failureWilliam T Abraham
Division of Cardiovascular Medicine, University of Kentucky College of Medicine, Lexington 40536 0284, USA
N Engl J Med 346:1845-53. 2002..We conducted a double-blind trial to evaluate this therapeutic approach... - Cardiac resynchronization therapy for heart failure: biventricular pacing and beyondWilliam T Abraham
Division of Cardiovascular Medicine, Gill Heart Institute, Heart Failure and Cardiac Transplantation Program, University of Kentucky College of Medicine, Lexington, Kentucky 49536, USA
Curr Opin Cardiol 17:346-52. 2002..In addition, the results of recently completed clinical trials, as well as the status of ongoing clinical trials, are reviewed... - Beta-blocker dosing in community-based treatment of heart failureMichael B Fowler
Division of Cardiovascular Medicine, Stanford University Medical Center, Palo Alto, CA, USA
Am Heart J 153:1029-36. 2007..Community patients with heart failure (HF) are older, less often treated by HF specialists, and have more comorbidity than those in randomized clinical trials. These differences might affect beta-blocker prescribing in HF... - Cardiac resynchronization therapy for the management of chronic heart failureWilliam T Abraham
Department of Internal Medicine, Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA
Am Heart Hosp J 1:55-61. 2003..Thus, cardiac resynchronization therapy should be routinely considered in eligible NYHA class III and IV heart failure patients with ventricular dyssynchrony... - Clinical and hemodynamic effects of nesiritide (B-type natriuretic peptide) in patients with decompensated heart failure receiving beta blockersWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH 43210 1252, USA
Congest Heart Fail 11:59-64. 2005..Thus, the clinical and hemodynamic benefits and safety of nesiritide are preserved in decompensated congestive heart failure patients receiving chronic beta blockade... - Percutaneous left ventricular partitioning in patients with chronic heart failure and a prior anterior myocardial infarction: Results of the PercutAneous Ventricular RestorAtion in Chronic Heart failUre PaTiEnts TrialErnest L Mazzaferri
Division of Cardiovascular Medicine, The Ohio State University Heart and Vascular Center, 473 West 12th Ave, Columbus, OH 43210 1252, USA
Am Heart J 163:812-820.e1. 2012..The aim of this study was to assess the feasibility, safety, and preliminary efficacy of a novel percutaneous left ventricular partitioning device (VPD) in patients with chronic heart failure (HF) and a prior anterior myocardial infarction... - Diuretics for the treatment of acute decompensated heart failureSrinivas Iyengar
Division of Cardiovascular Medicine, The Ohio State University, 473 West 12th Avenue, Rm 110P DHLRI, Columbus, Ohio 43210 1252, USA
Heart Fail Rev 12:125-30. 2007..Given this reality and until further information is available about the most ideal utilization of these medications, diuretics will continue to represent a double-edged sword for physicians treating this disease process... - In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE)William T Abraham
Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA
J Am Coll Cardiol 46:57-64. 2005..We sought to compare the in-hospital mortality of patients with acute decompensated heart failure (ADHF) who were receiving parenteral treatment with one of four intravenous vasoactive medications... - Practical considerations for switching beta-blockers in heart failure patientsWilliam T Abraham
Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University Heart Center, Columbus, Ohio, USA
Rev Cardiovasc Med 5:S36-44. 2004.... - Pharmacologic therapies across the continuum of left ventricular dysfunctionWilliam T Abraham
Division of Cardiovascular Medicine, Ohio State University Medical Center, Columbus, Ohio 43210, USA
Am J Cardiol 102:21G-28G. 2008..This review illustrates the impact of these therapies on post-MI LVD patients using evidence from multiple clinical trials. In addition, current and emerging treatments for acute decompensated HF will be outlined... - Cardiology patient page. Cardiac resynchronization therapy: a better and longer life for patients with advanced heart failureSrinivas Iyengar
Division of Cardiovascular Medicine, Ohio State University, Columbus, OH 43210-1252, USA
Circulation 112:e236-7. 2005 - Aquaretic effect of lixivaptan, an oral, non-peptide, selective V2 receptor vasopressin antagonist, in New York Heart Association functional class II and III chronic heart failure patientsWilliam T Abraham
The Ohio State University Heart Center, Division of Cardiovascular Medicine, Columbus, Ohio 43210 1252, USA
J Am Coll Cardiol 47:1615-21. 2006..The purpose of this study was to examine the renal effects of a V2 receptor arginine vasopressin (AVP) antagonist in heart failure... - Highlights of Heart Rhythm 2004, the Annual Scientific Sessions of the Heart Rhythm Society: May 19 to 22, 2004, in San Francisco, CaliforniaAnne B Curtis
Division of Cardiovascular Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
J Am Coll Cardiol 44:1550-6. 2004.... - Beyond diuretics: management of volume overload in acute heart failure syndromesJames A Hill
Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA
Am J Med 119:S37-44. 2006.... - Cardiac resynchronization therapy is important for all patients with congestive heart failure and ventricular dyssynchronyWilliam T Abraham
Department Internal Medicine, Division of Cardiovascular Medicine, and The Davis Heart and Lung Research Institute, Ohio State University, Columbus, USA
Circulation 114:2692-8; discussion 2698. 2006 - Tolerability, safety, and efficacy of beta-blockade in black patients with heart failure in the community setting: insights from a large prospective beta-blocker registryWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University School of Medicine, Columbus, OH, USA
Congest Heart Fail 13:16-21. 2007..9% vs 7.5%, hazard ratio 1.2 vs 1.0, P=.276). Thus carvedilol was similarly effective in blacks and whites with HF in the community setting, consistent with carvedilol clinical trials... - Nesiritide for the treatment of congestive heart failureSrinivas Iyengar
Division of Cardiovascular Medicine, The Ohio State University Heart Center, Columbus, OH 43210 1252, USA
Expert Opin Pharmacother 5:901-7. 2004..Overall, nesiritide represents an effective and safe therapeutic option for the treatment of decompensated CHF... - A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: rationale, design, and baseline patient characteristicsWilliam T Abraham
The Ohio State University Heart Center, Division of Cardiovascular Medicine, Columbus, OH 43210 1252, USA
Am Heart J 156:641-648.e1. 2008..Baseline characteristics for patients randomized in this trial are also presented... - Nesiritide in acute decompensated heart failure: a pooled analysis of randomized controlled trialsWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA
Clin Cardiol 33:484-9. 2010..This study used relevant data from all RCTs of nesiritide in ADHF completed as of June 2006 to independently estimate the effect of nesiritide on 30- and 180-day mortality... - Switching to evidence-based once-daily beta-blockers for improved adherence to medication across the continuum of post-myocardial infarction left ventricular dysfunction and heart failureWilliam T Abraham
Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210 1252, USA
Congest Heart Fail 14:272-80. 2008..Algorithms are provided for switching patients with heart failure or post-MI LVD from another beta-blocker to carvedilol CR... - Intrathoracic impedance monitoring for early detection of impending heart failure decompensationWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University College of Medicine and Public Health, Columbus, OH 43210, USA
Congest Heart Fail 13:113-5. 2007..This review discusses the basic concepts underlying intrathoracic impedance monitoring, the clinical evidence supporting its use, and some common pitfalls to avoid when interpreting intrathoracic impedance data... - Cardiac resynchronization therapy: a review of clinical trials and criteria for identifying the appropriate patientWilliam T Abraham
Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA
Rev Cardiovasc Med 4:S30-7. 2003..Given these findings, cardiac resynchronization therapy should be routinely considered in eligible NYHA Class III and IV heart failure patients with ventricular dyssynchrony... - Rationale and design of the treatment of hyponatremia based on lixivaptan in NYHA class III/IV cardiac patient evaluation (THE BALANCE) studyWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University Heart Center, Columbus, USA
Clin Transl Sci 3:249-53. 2010..BALANCE seeks to address unmet questions regarding the use of vasopressin antagonists including their effects on cognitive function and clinical outcomes in patients with hyponatremia and worsening heart failure... - New approaches to monitoring heart failure before symptoms appearWilliam T Abraham
Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, USA
Rev Cardiovasc Med 7:S33-41. 2006..IHM systems may extend such monitoring capabilities. Both emerging approaches for monitoring patients with heart failure may alert clinicians (and possibly patients) to impending decompensation before symptoms appear... - Cardiac resynchronization treatment of heart failureAyesha Hasan
Division of Cardiovascular Medicine, The Ohio State University College of Medicine, Columbus, Ohio 43210 1252, USA
Annu Rev Med 58:63-74. 2007..With the exponential rise in implants, new issues have emerged, such as optimal device programming, identifying appropriate candidates, and accounting for cases without clinical benefit from CRT... - Reproducibility of peak oxygen uptake and other cardiopulmonary exercise parameters: implications for clinical trials and clinical practiceSteven J Keteyian
Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
Chest 138:950-5. 2010.... - Cardiac resynchronization therapy for heart failureWilliam T Abraham
Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA
Circulation 108:2596-603. 2003 - Epidemiology of sudden cardiac death in patients with heart failureMahmoud Houmsse
Division of Cardiovascular Medicine, Department of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Suite 200, 473 West 12th Avenue, Columbus, OH 43210, USA
Heart Fail Clin 7:147-55, vii. 2011..This article discusses the incidence, prediction, and prevention of SCD in CHF due to ischemic and nonischemic cardiomyopathy... - Diabetes, hypertension, and renal insufficiency in post-myocardial infarction cardiovascular riskWilliam T Abraham
Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, Ohio, USA
Rev Cardiovasc Med 4:S30-6. 2003..Results from 1 recent study of the beta-blocker, carvedilol, have shown further that these benefits extend to high-risk patients with either diabetes or hypertension... - Coronary-artery bypass surgery in patients with left ventricular dysfunctionEric J Velazquez
Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA
N Engl J Med 364:1607-16. 2011..The role of coronary-artery bypass grafting (CABG) in the treatment of patients with coronary artery disease and heart failure has not been clearly established... - Treatment of anemia with darbepoetin alfa in heart failureWilliam T Abraham
Division of Cardiovascular Medicine, The Ohio State University Medical Center, Davis Heart and Lung Research Institute, Columbus, OH 43210, USA
Congest Heart Fail 16:87-95. 2010..These results suggest that DA is well tolerated, corrects HF-associated anemia, and may have favorable effects on clinical outcomes... - Higher expectations for management of heart failure: current recommendationsWilliam T Abraham
Division of Cardiovascular Medicine, University of Kentucky Medical Center, Lexington, USA
J Am Board Fam Pract 15:39-49. 2002..Management of heart failure has thus entered a new era of more effective pharmacotherapy, often delivered within the primary care setting... - Effect of nesiritide versus milrinone in the treatment of acute decompensated heart failureDaniel A Lewis
College of Pharmacy, University of Kentucky Chandler Medical Center, Lexington, USA
Am J Health Syst Pharm 60:S16-20. 2003..Total cost of therapy was lower in the nesiritide group as compared to those patients treated with milrinone... - Pharmacogenomics and heart failure: tailor-made therapy?Srinivas Iyengar
The OSU Heart Center, Division of Cardiovascular Medicine, 473 West 12th Avenue, Room 110P DHLRI, Columbus, OH 43210-1252, USA
Congest Heart Fail 10:273, 288. 2004 - Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failureAlan S Maisel
University of California, San Diego, Veterans Affairs Medical Center, San Diego 92161, USA
N Engl J Med 347:161-7. 2002..B-type natriuretic peptide is released from the cardiac ventricles in response to increased wall tension... - Resynchronisation therapy in heart failure: searching for predictorsMin Pu
Heart 94:4-5. 2008 - Chronic cardiac resynchronization therapy and reverse ventricular remodeling in a model of nonischemic cardiomyopathyYoshinori Nishijima
Department of Veterinary Biosciences, United States
Life Sci 81:1152-9. 2007..The beneficial effects of CRT may be attributable, in part, to improved LV myocyte function... - Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF)Gregg C Fonarow
Department of Medicine, University of California Los Angeles Medical Center, 10833 LeConte Ave, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
Arch Intern Med 167:1493-502. 2007..We sought to evaluate the effect of a national hospital-based initiative on quality of care in patients hospitalized with HF... - Safety and efficacy of nesiritide for acute decompensated heart failure: recent literature and upcoming trialsBrian Hiestand
Department of Emergency Medicine, The Ohio State University, 149 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA
Curr Cardiol Rep 9:182-6. 2007..We review the recent evidence regarding the efficacy and safety profile of nesiritide, and discuss upcoming trials designed to address concerns regarding safety and the comparative efficacy of nesiritide... - Diagnostic value of B-Type natriuretic peptide and chest radiographic findings in patients with acute dyspneaCathrine W Knudsen
, Oslo, Norway
Am J Med 116:363-8. 2004..CONCLUSION: In patients presenting to the emergency department with acute dyspnea, BNP levels and chest radiographs provide complementary diagnostic information that may be useful in the early evaluation of heart failure... - Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD TrialJames B Young
Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
JAMA 289:2685-94. 2003.... - Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)Gregg C Fonarow
Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA 90095 1679, USA
Am Heart J 153:82.e1-11. 2007.... - Heart failure in community practice: relationship to age and sex in a beta-blocker registryJoseph A Franciosa
Zena and Michael A Wiener Cardiovascular Institute, Mt Sinai School of Medicine, and the Weill Medical College of Cornell University, New York, NY, USA
Congest Heart Fail 12:317-23. 2006..001). Characteristics of women and the elderly with HF in the community suggest increased risk, but both populations respond well after initiating carvedilol... - Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemiaJalal K Ghali
Wayne State University, Detroit, Mich, USA
Circulation 117:526-35. 2008..The Study of Anemia in Heart Failure Trial (STAMINA-HeFT) is the largest multicenter, randomized, double-blind, placebo-controlled trial to date evaluating the effect of treating anemia in HF... - Baseline characteristics of patients randomized in The Resynchronization Reverses Remodeling In Systolic Left Ventricular Dysfunction (REVERSE) studyCecilia Linde
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
Congest Heart Fail 14:66-74. 2008..1% of patients. Compared with previous randomized cardiac resynchronization therapy trials, REVERSE patients are on better pharmacologic treatment, are younger, and have a narrower QRS width despite similar LV dysfunction... - Congestion is an important diagnostic and therapeutic target in heart failureMihai Gheorghiade
Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Rev Cardiovasc Med 7:S12-24. 2006..Identification of hemodynamic congestion, before the clinical manifestations appear, may potentially prevent hospitalization and slow the progression of HF by allowing life-saving interventions to be implemented sooner... - B-type natriuretic peptide and clinical judgment in emergency diagnosis of heart failure: analysis from Breathing Not Properly (BNP) Multinational StudyPeter A McCullough
University of California, Veteran s Affairs Medical Center, San Diego, USA
Circulation 106:416-22. 2002..We sought to determine the degree to which B-type natriuretic peptide (BNP) adds to clinical judgment in the diagnosis of congestive heart failure (CHF)... - Carvedilol improves left ventricular function in heart failure patients with idiopathic dilated cardiomyopathy and a wide range of sympathetic nervous system function as measured by iodine 123 metaiodobenzylguanidineMyron C Gerson
Division of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
J Nucl Cardiol 9:608-15. 2002..The goal of this study was to determine the effect of chronic carvedilol treatment in patients with cardiac sympathetic nerve dysfunction of varying severity... - B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational StudyPeter A McCullough
University of California, San Diego Veteran s Affairs Medical Center, San Diego, CA, USA
Am J Kidney Dis 41:571-9. 2003..However, relationships between BNP, renal function, and heart failure as an emergency diagnosis are unknown... - Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failureMartin G St John Sutton
Division of Cardiology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA
Circulation 107:1985-90. 2003..The purpose of the present study was to determine whether improvements in left ventricular (LV) size and function were associated with CRT... - Electrophysiological aids in congestive heart failure: supporting and synchronizing systoleWilliam T Abraham
Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210 1252, USA
Med Clin North Am 87:509-21. 2003..Ongoing and future clinical trials should help to further validate the role of cardiac resynchronization in the treatment of patients with systolic HF... - Bedside B-Type natriuretic peptide in the emergency diagnosis of heart failure with reduced or preserved ejection fraction. Results from the Breathing Not Properly Multinational StudyAlan S Maisel
Cardiology 111 A, San Diego VA Medical Center, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
J Am Coll Cardiol 41:2010-7. 2003..This study examines B-type natriuretic peptide (BNP) levels in patients with systolic versus non-systolic dysfunction presenting with shortness of breath... - Cardiac resynchronization therapy improves heart rate variability in patients with symptomatic heart failurePhilip B Adamson
Department of Internal Medicine, Cardiovascular Disease Section, University of Oklahoma Health Sciences Center, PO Box 26901, 920 SL Young Boulevard, WP3120, Oklahoma City, Okla 73104, USA
Circulation 108:266-9. 2003..The present study examined whether an improvement in ventricular performance from resynchronization therapy changes the autonomic control of heart rate... - Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rateGuido Boerrigter
Cardiorenal Research Laboratory, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Card Fail 14:539-46. 2008..We hypothesized that CRT would improve glomerular filtration rate as estimated by the abbreviated Modification of Diet in Renal Disease equation (eGFR)... - Predictors of clinical outcomes in patients given carvedilol for heart failureBarry Greenberg
University of California, San Diego, School of Medicine, San Diego, California, USA
Am J Cardiol 98:1480-4. 2006..In this unselected community population, these historical factors were better predictors of risk than the left ventricular ejection fraction... - Continuous autonomic assessment in patients with symptomatic heart failure: prognostic value of heart rate variability measured by an implanted cardiac resynchronization devicePhilip B Adamson
Department of Medicine, Cardiovascular Disease and Physiology, University of Oklahoma Health Sciences Center, 920 SL Young Blvd, WP3120, Oklahoma City, OK 73104, USA
Circulation 110:2389-94. 2004..Long-term continuous HRV can be measured from an implantable device, but the clinical value of these measurements is unknown... - Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failureMihai Gheorghiade
Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
JAMA 296:2217-26. 2006..These findings may have important therapeutic implications because characteristics and outcomes differ greatly among patients with heart failure with varying SBP... - Rationale and design of a randomized controlled trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with asymptomatic left ventricular dysfunction with previous symptoms or mild heart failure--the REsynchronization reVCecilia Linde
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
Am Heart J 151:288-94. 2006..The effects of CRT on HF outcomes in patients with asymptomatic left ventricular dysfunction (ALVD) or mild HF remain to be determined... - Safety of transvenous cardiac resynchronization system implantation in patients with chronic heart failure: combined results of over 2,000 patients from a multicenter study programAngel R Leon
Carlyle Fraser Heart Center Division of Cardiology, Emory University, Atlanta, Georgia, USA
J Am Coll Cardiol 46:2348-56. 2005..The purpose of this study was to evaluate the safety of implanting a cardiac resynchronization therapy (CRT) system... - Cardiac resynchronization with sequential biventricular pacing for the treatment of moderate-to-severe heart failureAngel R Leon
Carlyle Fraser Heart Center Division of Cardiology, Emory University, Atlanta, Georgia, USA
J Am Coll Cardiol 46:2298-304. 2005..The InSync III study evaluated sequential cardiac resynchronization therapy (CRT) in patients with moderate-to-severe heart failure and prolonged QRS... - Relationship between obesity and B-type natriuretic peptide levelsJames McCord
Henry Ford Heart and Vascular Institute, Henry Ford Health System, Detroit, Mich, USA
Arch Intern Med 164:2247-52. 2004..When considering demographics, severity of disease, and renal function, BMI is not independently related to BNP levels in a small subgroup when detailed information about CHF severity is known... - B-type natriuretic peptide levels in patients in the emergency department with possible heart failure and previous stable angina pectoris and/or healed myocardial infarctionJames McCord
Henry Ford Health System, Detroit, Michigan, USA
Am J Cardiol 96:1370-3. 2005..However, in patients who did not have heart failure, there was a relation between BNP levels and previous stable angina pectoris and/or healed myocardial infarction but no significant independent relation in multiple regression analysis... - Relationship of B-type natriuretic peptide and anemia in patients with and without heart failure: a substudy from the Breathing Not Properly (BNP) Multinational StudyAlan H B Wu
Department of Laboratory Medicine, University of California, San Francisco, San Francisco General Hospital, 1001 Potrero Ave, California 94110, USA
Am J Hematol 80:174-80. 2005..Among systolic HF patients, the presence of a low hemoglobin concentration is not a factor in the interpretation of BNP results... - Canine nonischemic left ventricular dysfunction: a model of chronic human cardiomyopathyYoshinori Nishijima
Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210, USA
J Card Fail 11:638-44. 2005.... - Impact of atrial fibrillation on the diagnostic performance of B-type natriuretic peptide concentration in dyspneic patients: an analysis from the breathing not properly multinational studyCathrine Wold Knudsen
, Oslo, Norway
J Am Coll Cardiol 46:838-44. 2005..CONCLUSIONS: In patients without, but not in those with HF, the presence of AF is associated with higher circulating BNP levels, suggesting that a higher diagnostic threshold should be used in patients with AF... - B-type natriuretic peptide and echocardiographic determination of ejection fraction in the diagnosis of congestive heart failure in patients with acute dyspneaPhilippe Gabriel Steg
Cardiology, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
Chest 128:21-9. 2005..Echocardiography and B-type natriuretic peptide (BNP) are diagnostic tests for congestive heart failure (CHF), but an emergency diagnosis can be difficult... - Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)Kirkwood F Adams
Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA
Am Heart J 149:209-16. 2005..Most available data on these patients are limited by patient selection criteria and study design of clinical trials and single-center studies... - Predictors of response to cardiac resynchronization therapy (PROSPECT)--study designCheuk Man Yu
Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
Am Heart J 149:600-5. 2005..The primary response criteria are improvement in the heart failure Clinical Composite Score and left ventricular reverse remodeling. Enrollment began in March 2004 and is expected to conclude early 2005... - Cardiac resynchronization therapyWilliam T Abraham
Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210 1252, USA
Prog Cardiovasc Dis 48:232-8. 2006..Cardiac resynchronization therapy has been shown to significantly improve LV structure and function, New York Heart Association functional class, exercise tolerance, quality of life, and morbidity and mortality... - Predictors of elevated B-type natriuretic peptide concentrations in dyspneic patients without heart failure: an analysis from the breathing not properly multinational studyCathrine W Knudsen
University of California, San Diego, Veteran's Affairs Medical Center, San Diego, CA, USA
Ann Emerg Med 45:573-80. 2005..CONCLUSION: Knowledge of these commonly obtained variables should aid clinicians in the interpretation of moderately elevated BNP results in patients presenting with acute dyspnea in the emergency department... - Validation and clinical utility of a simple in-home testing tool for sleep-disordered breathing and arrhythmias in heart failure: results of the Sleep Events, Arrhythmias, and Respiratory Analysis in Congestive Heart Failure (SEARCH) studyWilliam T Abraham
The Ohio State University Heart Center, Davis Heart and Lung Research Institute, 473 West 12th Avenue, Columbus, OH 43210 1252, USA
Congest Heart Fail 12:241-7; quiz 248-9. 2006..The device was judged by 80% of patients to be easy or very easy to use, and 74% of patients expressed a preference for the in-home system. Therefore, this system represents a reasonable home testing device in these patients... - Future therapies for heart failureRobin J Trupp
The Heart and Lung Research Institute, The Ohio State University 473 West 12th Avenue, Columbus, OH 43210, USA
Crit Care Nurs Clin North Am 15:525-30, x. 2003..This article discusses recently approved drugs and devices and clinical trials that may affect the management of this challenging disease... - Noninvasive calibration of cardiac pressure transducers in patients with heart failure: an aid to implantable hemodynamic monitoring and therapeutic guidanceDougal McClean
Division of Cardiology, Department of Medicine, and the Research Institute at Cedars-Sinai Medical Center, Los Angeles, California, USA
J Card Fail 12:568-76. 2006.... - How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational StudyLori B Daniels
University of California, San Diego, CA, USA
Am Heart J 151:999-1005. 2006..A lower cut-point (BNP > or = 54 pg/mL) should be used in severely obese patients to preserve sensitivity. A higher cut-point in lean patients (BNP > or = 170 pg/mL) could be used to increase specificity... - Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failureWilliam T Abraham
Ohio State University Heart Center, Division of Cardiovascular Medicine, 473 W 12th Ave, Room 110P DHLRI, Columbus, OH 43210 1252
Circulation 110:2864-8. 2004..The effects of cardiac resynchronization therapy (CRT) in patients with mildly symptomatic heart failure have not been fully elucidated... - Importance of in-hospital initiation of evidence-based medical therapies for heart failure-a reviewGregg C Fonarow
Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1679, USA
Am J Cardiol 94:1155-60. 2004.... - Clinical predictors and timing of New York Heart Association class improvement with cardiac resynchronization therapy in patients with advanced chronic heart failure: results from the Multicenter InSync Randomized Clinical Evaluation (MIRACLE) and MulticeLuis A Pires
The Heart Rhythm Center, Division of Cardiology, St John Hospital and Medical Center, Detroit, MI 48236, USA
Am Heart J 151:837-43. 2006..The purpose of this analysis is to identify predictors and characterize the timing of response to CRT in patients with advanced heart failure... - The effect of diabetes on B-type natriuretic peptide concentrations in patients with acute dyspnea: an analysis from the Breathing Not Properly Multinational StudyAlan H B Wu
Department of Pathology and Laboratory Medicine, Hartford Hospital, Connecticut, USA
Diabetes Care 27:2398-404. 2004..We determined the effect of diabetes on B-type natriuretic peptide (BNP) concentrations in patients presenting to the emergency department with dyspnea... - Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and designGregg C Fonarow
Department of Medicine, UCLA Medical Center, Los Angeles, Calif, USA
Am Heart J 148:43-51. 2004..The ultimate aim of this program is to improve the standard of HF care in the hospital and outpatient settings and increase the use of evidence-based therapeutic strategies to save lives... - Beta-blocker therapy for heart failure outside the clinical trial setting: findings of a community-based registryJoseph A Franciosa
Mount Sinai School of Medicine and Weill Medical College, Cornell University, New York, NY, USA
Am Heart J 148:718-26. 2004..beta-Blockers reduce morbidity and mortality rates in heart failure (HF) clinical trials, but it is unknown whether these findings persist in the community setting... - Continuous aortic flow augmentation: a pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failureMarvin A Konstam
Tufts New England Medical Center, Tufts University, Boston, MA, USA
Circulation 112:3107-14. 2005.... - Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry)James B Young
Department of Cardiovascular Medicine, Heart Failure Section, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Am J Cardiol 101:223-30. 2008..Lower hemoglobin is associated with higher morbidity and mortality in hospitalized patients with HF...