William T Abraham

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Does quality of life evidence assist in the selection of patients for resynchronization therapy?
    Peter A McCullough
    Department of Basic Science, Cardiology Section, University of Missouri Kansas City School of Medicine, Truman Medical Center, Kansas City, MO, USA
    Card Electrophysiol Rev 7:71-6. 2003
  2. ncbi request reprint Predictors of remodeling in the CRT era: influence of mitral regurgitation, BNP, and gender
    Thomas P Cappola
    Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Card Fail 12:182-8. 2006
  3. ncbi request reprint Cardiac resynchronization in chronic heart failure
    William T Abraham
    Division of Cardiovascular Medicine, University of Kentucky College of Medicine, Lexington 40536 0284, USA
    N Engl J Med 346:1845-53. 2002
  4. ncbi request reprint Cardiac resynchronization therapy for heart failure: biventricular pacing and beyond
    William T Abraham
    Division of Cardiovascular Medicine, Gill Heart Institute, Heart Failure and Cardiac Transplantation Program, University of Kentucky College of Medicine, Lexington, Kentucky 49536, USA
    Curr Opin Cardiol 17:346-52. 2002
  5. ncbi request reprint Beta-blocker dosing in community-based treatment of heart failure
    Michael B Fowler
    Division of Cardiovascular Medicine, Stanford University Medical Center, Palo Alto, CA, USA
    Am Heart J 153:1029-36. 2007
  6. ncbi request reprint Cardiac resynchronization therapy for the management of chronic heart failure
    William T Abraham
    Department of Internal Medicine, Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA
    Am Heart Hosp J 1:55-61. 2003
  7. ncbi request reprint Clinical and hemodynamic effects of nesiritide (B-type natriuretic peptide) in patients with decompensated heart failure receiving beta blockers
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH 43210 1252, USA
    Congest Heart Fail 11:59-64. 2005
  8. doi request reprint Oral lixivaptan effectively increases serum sodium concentrations in outpatients with euvolemic hyponatremia
    William T Abraham
    Division of Cardiovascular Medicine, Ohio State University, Columbus, Ohio 43210 1252, USA
    Kidney Int 82:1215-22. 2012
  9. doi request reprint Percutaneous left ventricular partitioning in patients with chronic heart failure and a prior anterior myocardial infarction: Results of the PercutAneous Ventricular RestorAtion in Chronic Heart failUre PaTiEnts Trial
    Ernest L Mazzaferri
    Division of Cardiovascular Medicine, The Ohio State University Heart and Vascular Center, 473 West 12th Ave, Columbus, OH 43210 1252, USA
    Am Heart J 163:812-820.e1. 2012
  10. ncbi request reprint Diuretics for the treatment of acute decompensated heart failure
    Srinivas Iyengar
    Division of Cardiovascular Medicine, The Ohio State University, 473 West 12th Avenue, Rm 110P DHLRI, Columbus, Ohio 43210 1252, USA
    Heart Fail Rev 12:125-30. 2007

Detail Information

Publications88

  1. ncbi request reprint Does quality of life evidence assist in the selection of patients for resynchronization therapy?
    Peter A McCullough
    Department of Basic Science, Cardiology Section, University of Missouri Kansas City School of Medicine, Truman Medical Center, Kansas City, MO, USA
    Card Electrophysiol Rev 7:71-6. 2003
    ..In conclusion, assessment of quality of life before device implantation is necessary in order to select those individuals who are most likely to benefit from cardiac resynchronization therapy...
  2. ncbi request reprint Predictors of remodeling in the CRT era: influence of mitral regurgitation, BNP, and gender
    Thomas P Cappola
    Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Card Fail 12:182-8. 2006
    ..We analyzed quantitative echocardiographic data from a large heart failure cohort receiving medical and cardiac resynchronization therapy (CRT) to determine baseline predictors of progressive left ventricular (LV) enlargement...
  3. ncbi request reprint Cardiac resynchronization in chronic heart failure
    William T Abraham
    Division of Cardiovascular Medicine, University of Kentucky College of Medicine, Lexington 40536 0284, USA
    N Engl J Med 346:1845-53. 2002
    ..We conducted a double-blind trial to evaluate this therapeutic approach...
  4. ncbi request reprint Cardiac resynchronization therapy for heart failure: biventricular pacing and beyond
    William T Abraham
    Division of Cardiovascular Medicine, Gill Heart Institute, Heart Failure and Cardiac Transplantation Program, University of Kentucky College of Medicine, Lexington, Kentucky 49536, USA
    Curr Opin Cardiol 17:346-52. 2002
    ..In addition, the results of recently completed clinical trials, as well as the status of ongoing clinical trials, are reviewed...
  5. ncbi request reprint Beta-blocker dosing in community-based treatment of heart failure
    Michael B Fowler
    Division of Cardiovascular Medicine, Stanford University Medical Center, Palo Alto, CA, USA
    Am Heart J 153:1029-36. 2007
    ..Community patients with heart failure (HF) are older, less often treated by HF specialists, and have more comorbidity than those in randomized clinical trials. These differences might affect beta-blocker prescribing in HF...
  6. ncbi request reprint Cardiac resynchronization therapy for the management of chronic heart failure
    William T Abraham
    Department of Internal Medicine, Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA
    Am Heart Hosp J 1:55-61. 2003
    ..Thus, cardiac resynchronization therapy should be routinely considered in eligible NYHA class III and IV heart failure patients with ventricular dyssynchrony...
  7. ncbi request reprint Clinical and hemodynamic effects of nesiritide (B-type natriuretic peptide) in patients with decompensated heart failure receiving beta blockers
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH 43210 1252, USA
    Congest Heart Fail 11:59-64. 2005
    ..Thus, the clinical and hemodynamic benefits and safety of nesiritide are preserved in decompensated congestive heart failure patients receiving chronic beta blockade...
  8. doi request reprint Oral lixivaptan effectively increases serum sodium concentrations in outpatients with euvolemic hyponatremia
    William T Abraham
    Division of Cardiovascular Medicine, Ohio State University, Columbus, Ohio 43210 1252, USA
    Kidney Int 82:1215-22. 2012
    ..2%). Overall, lixivaptan was considered safe and well-tolerated. Thus, oral lixivaptan can be safely initiated in the outpatient setting and effectively increases serum sodium concentrations in outpatients with euvolemic hyponatremia...
  9. doi request reprint Percutaneous left ventricular partitioning in patients with chronic heart failure and a prior anterior myocardial infarction: Results of the PercutAneous Ventricular RestorAtion in Chronic Heart failUre PaTiEnts Trial
    Ernest L Mazzaferri
    Division of Cardiovascular Medicine, The Ohio State University Heart and Vascular Center, 473 West 12th Ave, Columbus, OH 43210 1252, USA
    Am Heart J 163:812-820.e1. 2012
    ..The aim of this study was to assess the feasibility, safety, and preliminary efficacy of a novel percutaneous left ventricular partitioning device (VPD) in patients with chronic heart failure (HF) and a prior anterior myocardial infarction...
  10. ncbi request reprint Diuretics for the treatment of acute decompensated heart failure
    Srinivas Iyengar
    Division of Cardiovascular Medicine, The Ohio State University, 473 West 12th Avenue, Rm 110P DHLRI, Columbus, Ohio 43210 1252, USA
    Heart Fail Rev 12:125-30. 2007
    ..Given this reality and until further information is available about the most ideal utilization of these medications, diuretics will continue to represent a double-edged sword for physicians treating this disease process...
  11. ncbi request reprint In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE)
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA
    J Am Coll Cardiol 46:57-64. 2005
    ..We sought to compare the in-hospital mortality of patients with acute decompensated heart failure (ADHF) who were receiving parenteral treatment with one of four intravenous vasoactive medications...
  12. doi request reprint Lixivaptan safely and effectively corrects serum sodium concentrations in hospitalized patients with euvolemic hyponatremia
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio 43210 1252, USA
    Kidney Int 82:1223-30. 2012
    ..After drug discontinuation, serum sodium concentrations decreased to near-baseline levels within 7 days. Thus, lixivaptan safely and effectively corrects serum sodium concentrations in patients with euvolemic hyponatremia...
  13. ncbi request reprint Practical considerations for switching beta-blockers in heart failure patients
    William T Abraham
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University Heart Center, Columbus, Ohio, USA
    Rev Cardiovasc Med 5:S36-44. 2004
    ....
  14. pmc Devices in the management of advanced, chronic heart failure
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, 473 West 12th Avenue, Room 110P, Columbus, OH 43210 1252, USA
    Nat Rev Cardiol 10:98-110. 2013
    ....
  15. ncbi request reprint Tolerability, safety, and efficacy of beta-blockade in black patients with heart failure in the community setting: insights from a large prospective beta-blocker registry
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University School of Medicine, Columbus, OH, USA
    Congest Heart Fail 13:16-21. 2007
    ..9% vs 7.5%, hazard ratio 1.2 vs 1.0, P=.276). Thus carvedilol was similarly effective in blacks and whites with HF in the community setting, consistent with carvedilol clinical trials...
  16. ncbi request reprint Highlights of Heart Rhythm 2004, the Annual Scientific Sessions of the Heart Rhythm Society: May 19 to 22, 2004, in San Francisco, California
    Anne B Curtis
    Division of Cardiovascular Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
    J Am Coll Cardiol 44:1550-6. 2004
    ....
  17. ncbi request reprint Cardiac resynchronization therapy is important for all patients with congestive heart failure and ventricular dyssynchrony
    William T Abraham
    Department Internal Medicine, Division of Cardiovascular Medicine, and The Davis Heart and Lung Research Institute, Ohio State University, Columbus, USA
    Circulation 114:2692-8; discussion 2698. 2006
  18. ncbi request reprint Beyond diuretics: management of volume overload in acute heart failure syndromes
    James A Hill
    Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA
    Am J Med 119:S37-44. 2006
    ....
  19. ncbi request reprint Aquaretic effect of lixivaptan, an oral, non-peptide, selective V2 receptor vasopressin antagonist, in New York Heart Association functional class II and III chronic heart failure patients
    William T Abraham
    The Ohio State University Heart Center, Division of Cardiovascular Medicine, Columbus, Ohio 43210 1252, USA
    J Am Coll Cardiol 47:1615-21. 2006
    ..The purpose of this study was to examine the renal effects of a V2 receptor arginine vasopressin (AVP) antagonist in heart failure...
  20. ncbi request reprint Nesiritide for the treatment of congestive heart failure
    Srinivas Iyengar
    Division of Cardiovascular Medicine, The Ohio State University Heart Center, Columbus, OH 43210 1252, USA
    Expert Opin Pharmacother 5:901-7. 2004
    ..Overall, nesiritide represents an effective and safe therapeutic option for the treatment of decompensated CHF...
  21. ncbi request reprint Cardiology patient page. Cardiac resynchronization therapy: a better and longer life for patients with advanced heart failure
    Srinivas Iyengar
    Division of Cardiovascular Medicine, Ohio State University, Columbus, OH 43210 1252, USA
    Circulation 112:e236-7. 2005
  22. doi request reprint Pharmacologic therapies across the continuum of left ventricular dysfunction
    William T Abraham
    Division of Cardiovascular Medicine, Ohio State University Medical Center, Columbus, Ohio 43210, USA
    Am J Cardiol 102:21G-28G. 2008
    ..This review illustrates the impact of these therapies on post-MI LVD patients using evidence from multiple clinical trials. In addition, current and emerging treatments for acute decompensated HF will be outlined...
  23. doi request reprint Nesiritide in acute decompensated heart failure: a pooled analysis of randomized controlled trials
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA
    Clin Cardiol 33:484-9. 2010
    ..This study used relevant data from all RCTs of nesiritide in ADHF completed as of June 2006 to independently estimate the effect of nesiritide on 30- and 180-day mortality...
  24. doi request reprint A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: rationale, design, and baseline patient characteristics
    William T Abraham
    The Ohio State University Heart Center, Division of Cardiovascular Medicine, Columbus, OH 43210 1252, USA
    Am Heart J 156:641-648.e1. 2008
    ..Baseline characteristics for patients randomized in this trial are also presented...
  25. doi request reprint Switching to evidence-based once-daily beta-blockers for improved adherence to medication across the continuum of post-myocardial infarction left ventricular dysfunction and heart failure
    William T Abraham
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210 1252, USA
    Congest Heart Fail 14:272-80. 2008
    ..Algorithms are provided for switching patients with heart failure or post-MI LVD from another beta-blocker to carvedilol CR...
  26. doi request reprint Rationale and design of the treatment of hyponatremia based on lixivaptan in NYHA class III/IV cardiac patient evaluation (THE BALANCE) study
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University Heart Center, Columbus, USA
    Clin Transl Sci 3:249-53. 2010
    ..BALANCE seeks to address unmet questions regarding the use of vasopressin antagonists including their effects on cognitive function and clinical outcomes in patients with hyponatremia and worsening heart failure...
  27. ncbi request reprint New approaches to monitoring heart failure before symptoms appear
    William T Abraham
    Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio, USA
    Rev Cardiovasc Med 7:S33-41. 2006
    ..IHM systems may extend such monitoring capabilities. Both emerging approaches for monitoring patients with heart failure may alert clinicians (and possibly patients) to impending decompensation before symptoms appear...
  28. ncbi request reprint Cardiac resynchronization treatment of heart failure
    Ayesha Hasan
    Division of Cardiovascular Medicine, The Ohio State University College of Medicine, Columbus, Ohio 43210 1252, USA
    Annu Rev Med 58:63-74. 2007
    ..With the exponential rise in implants, new issues have emerged, such as optimal device programming, identifying appropriate candidates, and accounting for cases without clinical benefit from CRT...
  29. ncbi request reprint Cardiac resynchronization therapy: a review of clinical trials and criteria for identifying the appropriate patient
    William T Abraham
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA
    Rev Cardiovasc Med 4:S30-7. 2003
    ..Given these findings, cardiac resynchronization therapy should be routinely considered in eligible NYHA Class III and IV heart failure patients with ventricular dyssynchrony...
  30. doi request reprint Reproducibility of peak oxygen uptake and other cardiopulmonary exercise parameters: implications for clinical trials and clinical practice
    Steven J Keteyian
    Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
    Chest 138:950-5. 2010
    ....
  31. ncbi request reprint Intrathoracic impedance monitoring for early detection of impending heart failure decompensation
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University College of Medicine and Public Health, Columbus, OH 43210, USA
    Congest Heart Fail 13:113-5. 2007
    ..This review discusses the basic concepts underlying intrathoracic impedance monitoring, the clinical evidence supporting its use, and some common pitfalls to avoid when interpreting intrathoracic impedance data...
  32. ncbi request reprint Cardiac resynchronization therapy for heart failure
    William T Abraham
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA
    Circulation 108:2596-603. 2003
  33. pmc Coronary-artery bypass surgery in patients with left ventricular dysfunction
    Eric J Velazquez
    Division of Cardiovascular Medicine, Duke University Medical Center, Durham, NC, USA
    N Engl J Med 364:1607-16. 2011
    ..The role of coronary-artery bypass grafting (CABG) in the treatment of patients with coronary artery disease and heart failure has not been clearly established...
  34. doi request reprint Epidemiology of sudden cardiac death in patients with heart failure
    Mahmoud Houmsse
    Division of Cardiovascular Medicine, Department of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Suite 200, 473 West 12th Avenue, Columbus, OH 43210, USA
    Heart Fail Clin 7:147-55, vii. 2011
    ..This article discusses the incidence, prediction, and prevention of SCD in CHF due to ischemic and nonischemic cardiomyopathy...
  35. ncbi request reprint Diabetes, hypertension, and renal insufficiency in post-myocardial infarction cardiovascular risk
    William T Abraham
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, Ohio, USA
    Rev Cardiovasc Med 4:S30-6. 2003
    ..Results from 1 recent study of the beta-blocker, carvedilol, have shown further that these benefits extend to high-risk patients with either diabetes or hypertension...
  36. doi request reprint Treatment of anemia with darbepoetin alfa in heart failure
    William T Abraham
    Division of Cardiovascular Medicine, The Ohio State University Medical Center, Davis Heart and Lung Research Institute, Columbus, OH 43210, USA
    Congest Heart Fail 16:87-95. 2010
    ..These results suggest that DA is well tolerated, corrects HF-associated anemia, and may have favorable effects on clinical outcomes...
  37. pmc Implantable cardiovascular sensors and computers: interventional heart failure strategies
    Sakima A Smith
    Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, Wexner Medical Center at The Ohio State University, 473 W 12th Avenue, Suite 200, Columbus, OH 43210, USA
    Curr Cardiol Rep 14:611-8. 2012
    ....
  38. ncbi request reprint Higher expectations for management of heart failure: current recommendations
    William T Abraham
    Division of Cardiovascular Medicine, University of Kentucky Medical Center, Lexington, USA
    J Am Board Fam Pract 15:39-49. 2002
    ..Each year 260,000 patients die as a direct or indirect result of the disorder, with annual costs estimated between $21 billion to $40 billion...
  39. ncbi request reprint Effect of nesiritide versus milrinone in the treatment of acute decompensated heart failure
    Daniel A Lewis
    College of Pharmacy, University of Kentucky Chandler Medical Center, Lexington, USA
    Am J Health Syst Pharm 60:S16-20. 2003
    ..Total cost of therapy was lower in the nesiritide group as compared to those patients treated with milrinone...
  40. ncbi request reprint Pharmacogenomics and heart failure: tailor-made therapy?
    Srinivas Iyengar
    The OSU Heart Center, Division of Cardiovascular Medicine, 473 West 12th Avenue, Room 110P DHLRI, Columbus, OH 43210 1252, USA
    Congest Heart Fail 10:273, 288. 2004
  41. pmc Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rate
    Guido Boerrigter
    Cardiorenal Research Laboratory, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Card Fail 14:539-46. 2008
    ..We hypothesized that CRT would improve glomerular filtration rate as estimated by the abbreviated Modification of Diet in Renal Disease equation (eGFR)...
  42. ncbi request reprint Future therapies for heart failure
    Robin J Trupp
    The Heart and Lung Research Institute, The Ohio State University 473 West 12th Avenue, Columbus, OH 43210, USA
    Crit Care Nurs Clin North Am 15:525-30, x. 2003
    ..This article discusses recently approved drugs and devices and clinical trials that may affect the management of this challenging disease...
  43. ncbi request reprint Baseline characteristics of patients randomized in The Resynchronization Reverses Remodeling In Systolic Left Ventricular Dysfunction (REVERSE) study
    Cecilia Linde
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    Congest Heart Fail 14:66-74. 2008
    ..1% of patients. Compared with previous randomized cardiac resynchronization therapy trials, REVERSE patients are on better pharmacologic treatment, are younger, and have a narrower QRS width despite similar LV dysfunction...
  44. doi request reprint Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia
    Jalal K Ghali
    Wayne State University, Detroit, Mich, USA
    Circulation 117:526-35. 2008
    ..The Study of Anemia in Heart Failure Trial (STAMINA-HeFT) is the largest multicenter, randomized, double-blind, placebo-controlled trial to date evaluating the effect of treating anemia in HF...
  45. ncbi request reprint Resynchronisation therapy in heart failure: searching for predictors
    Min Pu
    Heart 94:4-5. 2008
  46. ncbi request reprint Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
    Gregg C Fonarow
    Department of Medicine, University of California Los Angeles Medical Center, 10833 LeConte Ave, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Arch Intern Med 167:1493-502. 2007
    ..We sought to evaluate the effect of a national hospital-based initiative on quality of care in patients hospitalized with HF...
  47. ncbi request reprint Diagnostic value of B-Type natriuretic peptide and chest radiographic findings in patients with acute dyspnea
    Cathrine W Knudsen
    Ulleval University Hospital, Oslo, Norway
    Am J Med 116:363-8. 2004
    ..To compare chest radiographic findings and circulating B-type natriuretic peptide (BNP) levels as an adjunct to clinical findings in the diagnosis of heart failure in patients presenting with acute dyspnea...
  48. ncbi request reprint Continuous autonomic assessment in patients with symptomatic heart failure: prognostic value of heart rate variability measured by an implanted cardiac resynchronization device
    Philip B Adamson
    Department of Medicine, Cardiovascular Disease and Physiology, University of Oklahoma Health Sciences Center, 920 SL Young Blvd, WP3120, Oklahoma City, OK 73104, USA
    Circulation 110:2389-94. 2004
    ..Long-term continuous HRV can be measured from an implantable device, but the clinical value of these measurements is unknown...
  49. ncbi request reprint The effect of diabetes on B-type natriuretic peptide concentrations in patients with acute dyspnea: an analysis from the Breathing Not Properly Multinational Study
    Alan H B Wu
    Department of Pathology and Laboratory Medicine, Hartford Hospital, Connecticut, USA
    Diabetes Care 27:2398-404. 2004
    ..We determined the effect of diabetes on B-type natriuretic peptide (BNP) concentrations in patients presenting to the emergency department with dyspnea...
  50. ncbi request reprint Safety and efficacy of nesiritide for acute decompensated heart failure: recent literature and upcoming trials
    Brian Hiestand
    Department of Emergency Medicine, The Ohio State University, 149 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA
    Curr Cardiol Rep 9:182-6. 2007
    ..We review the recent evidence regarding the efficacy and safety profile of nesiritide, and discuss upcoming trials designed to address concerns regarding safety and the comparative efficacy of nesiritide...
  51. ncbi request reprint Safety of transvenous cardiac resynchronization system implantation in patients with chronic heart failure: combined results of over 2,000 patients from a multicenter study program
    Angel R Leon
    Carlyle Fraser Heart Center Division of Cardiology, Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 46:2348-56. 2005
    ..The purpose of this study was to evaluate the safety of implanting a cardiac resynchronization therapy (CRT) system...
  52. ncbi request reprint Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure
    Alan S Maisel
    University of California, San Diego, Veterans Affairs Medical Center, San Diego 92161, USA
    N Engl J Med 347:161-7. 2002
    ..B-type natriuretic peptide is released from the cardiac ventricles in response to increased wall tension...
  53. ncbi request reprint B-type natriuretic peptide and clinical judgment in emergency diagnosis of heart failure: analysis from Breathing Not Properly (BNP) Multinational Study
    Peter A McCullough
    University of California, Veteran s Affairs Medical Center, San Diego, USA
    Circulation 106:416-22. 2002
    ..We sought to determine the degree to which B-type natriuretic peptide (BNP) adds to clinical judgment in the diagnosis of congestive heart failure (CHF)...
  54. ncbi request reprint Carvedilol improves left ventricular function in heart failure patients with idiopathic dilated cardiomyopathy and a wide range of sympathetic nervous system function as measured by iodine 123 metaiodobenzylguanidine
    Myron C Gerson
    Division of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
    J Nucl Cardiol 9:608-15. 2002
    ..The goal of this study was to determine the effect of chronic carvedilol treatment in patients with cardiac sympathetic nerve dysfunction of varying severity...
  55. ncbi request reprint B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study
    Peter A McCullough
    University of California, San Diego Veteran s Affairs Medical Center, San Diego, CA, USA
    Am J Kidney Dis 41:571-9. 2003
    ..However, relationships between BNP, renal function, and heart failure as an emergency diagnosis are unknown...
  56. ncbi request reprint Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure
    Martin G St John Sutton
    Division of Cardiology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA
    Circulation 107:1985-90. 2003
    ..The purpose of the present study was to determine whether improvements in left ventricular (LV) size and function were associated with CRT...
  57. ncbi request reprint Electrophysiological aids in congestive heart failure: supporting and synchronizing systole
    William T Abraham
    Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210 1252, USA
    Med Clin North Am 87:509-21. 2003
    ..Ongoing and future clinical trials should help to further validate the role of cardiac resynchronization in the treatment of patients with systolic HF...
  58. ncbi request reprint Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial
    James B Young
    Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    JAMA 289:2685-94. 2003
    ....
  59. ncbi request reprint Bedside B-Type natriuretic peptide in the emergency diagnosis of heart failure with reduced or preserved ejection fraction. Results from the Breathing Not Properly Multinational Study
    Alan S Maisel
    Cardiology 111 A, San Diego VA Medical Center, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Am Coll Cardiol 41:2010-7. 2003
    ..This study examines B-type natriuretic peptide (BNP) levels in patients with systolic versus non-systolic dysfunction presenting with shortness of breath...
  60. ncbi request reprint Cardiac resynchronization therapy improves heart rate variability in patients with symptomatic heart failure
    Philip B Adamson
    Department of Internal Medicine, Cardiovascular Disease Section, University of Oklahoma Health Sciences Center, PO Box 26901, 920 SL Young Boulevard, WP3120, Oklahoma City, Okla 73104, USA
    Circulation 108:266-9. 2003
    ..The present study examined whether an improvement in ventricular performance from resynchronization therapy changes the autonomic control of heart rate...
  61. pmc Chronic cardiac resynchronization therapy and reverse ventricular remodeling in a model of nonischemic cardiomyopathy
    Yoshinori Nishijima
    Department of Veterinary Biosciences, United States
    Life Sci 81:1152-9. 2007
    ..The beneficial effects of CRT may be attributable, in part, to improved LV myocyte function...
  62. ncbi request reprint Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 153:82.e1-11. 2007
    ....
  63. ncbi request reprint Heart failure in community practice: relationship to age and sex in a beta-blocker registry
    Joseph A Franciosa
    Zena and Michael A Wiener Cardiovascular Institute, Mt Sinai School of Medicine, and the Weill Medical College of Cornell University, New York, NY, USA
    Congest Heart Fail 12:317-23. 2006
    ..001). Characteristics of women and the elderly with HF in the community suggest increased risk, but both populations respond well after initiating carvedilol...
  64. ncbi request reprint Predictors of elevated B-type natriuretic peptide concentrations in dyspneic patients without heart failure: an analysis from the breathing not properly multinational study
    Cathrine W Knudsen
    University of California, San Diego, Veteran s Affairs Medical Center, San Diego, CA, USA
    Ann Emerg Med 45:573-80. 2005
    ..The objective of the current study was to identify independent predictors of elevated BNP concentrations in the absence of congestive heart failure...
  65. ncbi request reprint Clinical predictors and timing of New York Heart Association class improvement with cardiac resynchronization therapy in patients with advanced chronic heart failure: results from the Multicenter InSync Randomized Clinical Evaluation (MIRACLE) and Multice
    Luis A Pires
    The Heart Rhythm Center, Division of Cardiology, St John Hospital and Medical Center, Detroit, MI 48236, USA
    Am Heart J 151:837-43. 2006
    ..The purpose of this analysis is to identify predictors and characterize the timing of response to CRT in patients with advanced heart failure...
  66. ncbi request reprint Cardiac resynchronization therapy
    William T Abraham
    Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210 1252, USA
    Prog Cardiovasc Dis 48:232-8. 2006
    ..Cardiac resynchronization therapy has been shown to significantly improve LV structure and function, New York Heart Association functional class, exercise tolerance, quality of life, and morbidity and mortality...
  67. ncbi request reprint Rationale and design of a randomized controlled trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with asymptomatic left ventricular dysfunction with previous symptoms or mild heart failure--the REsynchronization reV
    Cecilia Linde
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    Am Heart J 151:288-94. 2006
    ..The effects of CRT on HF outcomes in patients with asymptomatic left ventricular dysfunction (ALVD) or mild HF remain to be determined...
  68. ncbi request reprint Predictors of response to cardiac resynchronization therapy (PROSPECT)--study design
    Cheuk Man Yu
    Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Am Heart J 149:600-5. 2005
    ..The primary response criteria are improvement in the heart failure Clinical Composite Score and left ventricular reverse remodeling. Enrollment began in March 2004 and is expected to conclude early 2005...
  69. ncbi request reprint Cardiac resynchronization with sequential biventricular pacing for the treatment of moderate-to-severe heart failure
    Angel R Leon
    Carlyle Fraser Heart Center Division of Cardiology, Emory University, Atlanta, Georgia, USA
    J Am Coll Cardiol 46:2298-304. 2005
    ..The InSync III study evaluated sequential cardiac resynchronization therapy (CRT) in patients with moderate-to-severe heart failure and prolonged QRS...
  70. ncbi request reprint B-type natriuretic peptide levels in patients in the emergency department with possible heart failure and previous stable angina pectoris and/or healed myocardial infarction
    James McCord
    Henry Ford Health System, Detroit, Michigan, USA
    Am J Cardiol 96:1370-3. 2005
    ..However, in patients who did not have heart failure, there was a relation between BNP levels and previous stable angina pectoris and/or healed myocardial infarction but no significant independent relation in multiple regression analysis...
  71. ncbi request reprint Relationship of B-type natriuretic peptide and anemia in patients with and without heart failure: a substudy from the Breathing Not Properly (BNP) Multinational Study
    Alan H B Wu
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco General Hospital, 1001 Potrero Ave, California 94110, USA
    Am J Hematol 80:174-80. 2005
    ..Among systolic HF patients, the presence of a low hemoglobin concentration is not a factor in the interpretation of BNP results...
  72. ncbi request reprint Canine nonischemic left ventricular dysfunction: a model of chronic human cardiomyopathy
    Yoshinori Nishijima
    Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210, USA
    J Card Fail 11:638-44. 2005
    ..The mechanisms of cardiac remodeling during chronic heart failure remain poorly defined. We sought to advance a chronic canine model of nonischemic cardiomyopathy...
  73. ncbi request reprint B-type natriuretic peptide and echocardiographic determination of ejection fraction in the diagnosis of congestive heart failure in patients with acute dyspnea
    Philippe Gabriel Steg
    Cardiology, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Chest 128:21-9. 2005
    ..Echocardiography and B-type natriuretic peptide (BNP) are diagnostic tests for congestive heart failure (CHF), but an emergency diagnosis can be difficult...
  74. ncbi request reprint Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    Kirkwood F Adams
    Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA
    Am Heart J 149:209-16. 2005
    ..Most available data on these patients are limited by patient selection criteria and study design of clinical trials and single-center studies...
  75. ncbi request reprint How obesity affects the cut-points for B-type natriuretic peptide in the diagnosis of acute heart failure. Results from the Breathing Not Properly Multinational Study
    Lori B Daniels
    University of California, San Diego, CA, USA
    Am Heart J 151:999-1005. 2006
    ..We evaluated differential cut-points for BNP in diagnosing acute HF across body mass index levels to determine whether alternative cut-points can improve diagnosis...
  76. ncbi request reprint Noninvasive calibration of cardiac pressure transducers in patients with heart failure: an aid to implantable hemodynamic monitoring and therapeutic guidance
    Dougal McClean
    Division of Cardiology, Department of Medicine, and the Research Institute at Cedars Sinai Medical Center, Los Angeles, California, USA
    J Card Fail 12:568-76. 2006
    ..Implantable cardiac pressure monitors require assurance of calibration. This study evaluated if airway pressure responses during Valsalva maneuver (VM) can be used for calibrating intracardiac pressure transducers...
  77. ncbi request reprint Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure
    William T Abraham
    Ohio State University Heart Center, Division of Cardiovascular Medicine, 473 W 12th Ave, Room 110P DHLRI, Columbus, OH 43210 1252
    Circulation 110:2864-8. 2004
    ..The effects of cardiac resynchronization therapy (CRT) in patients with mildly symptomatic heart failure have not been fully elucidated...
  78. ncbi request reprint Predictors of clinical outcomes in patients given carvedilol for heart failure
    Barry Greenberg
    University of California, San Diego, School of Medicine, San Diego, California, USA
    Am J Cardiol 98:1480-4. 2006
    ..In this unselected community population, these historical factors were better predictors of risk than the left ventricular ejection fraction...
  79. ncbi request reprint Importance of in-hospital initiation of evidence-based medical therapies for heart failure-a review
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1679, USA
    Am J Cardiol 94:1155-60. 2004
    ....
  80. ncbi request reprint Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure
    Mihai Gheorghiade
    Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    JAMA 296:2217-26. 2006
    ..The association between systolic blood pressure (SBP) at admission, clinical characteristics, and outcomes in patients hospitalized for heart failure who have reduced or relatively preserved systolic function has not been well studied...
  81. ncbi request reprint Validation and clinical utility of a simple in-home testing tool for sleep-disordered breathing and arrhythmias in heart failure: results of the Sleep Events, Arrhythmias, and Respiratory Analysis in Congestive Heart Failure (SEARCH) study
    William T Abraham
    The Ohio State University Heart Center, Davis Heart and Lung Research Institute, 473 West 12th Avenue, Columbus, OH 43210 1252, USA
    Congest Heart Fail 12:241-7; quiz 248-9. 2006
    ..The device was judged by 80% of patients to be easy or very easy to use, and 74% of patients expressed a preference for the in-home system. Therefore, this system represents a reasonable home testing device in these patients...
  82. ncbi request reprint Relationship between obesity and B-type natriuretic peptide levels
    James McCord
    Henry Ford Heart and Vascular Institute, Henry Ford Health System, Detroit, Mich, USA
    Arch Intern Med 164:2247-52. 2004
    ..The relationships among B-type natriuretic peptide (BNP) levels, body mass index (BMI), and congestive heart failure (CHF) as an emergency diagnosis are unknown...
  83. ncbi request reprint Congestion is an important diagnostic and therapeutic target in heart failure
    Mihai Gheorghiade
    Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Rev Cardiovasc Med 7:S12-24. 2006
    ..Identification of hemodynamic congestion, before the clinical manifestations appear, may potentially prevent hospitalization and slow the progression of HF by allowing life-saving interventions to be implemented sooner...
  84. ncbi request reprint Impact of atrial fibrillation on the diagnostic performance of B-type natriuretic peptide concentration in dyspneic patients: an analysis from the breathing not properly multinational study
    Cathrine Wold Knudsen
    Ulleval University Hospital, Oslo, Norway
    J Am Coll Cardiol 46:838-44. 2005
    ....
  85. ncbi request reprint Beta-blocker therapy for heart failure outside the clinical trial setting: findings of a community-based registry
    Joseph A Franciosa
    Mount Sinai School of Medicine and Weill Medical College, Cornell University, New York, NY, USA
    Am Heart J 148:718-26. 2004
    ..beta-Blockers reduce morbidity and mortality rates in heart failure (HF) clinical trials, but it is unknown whether these findings persist in the community setting...
  86. ncbi request reprint Continuous aortic flow augmentation: a pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failure
    Marvin A Konstam
    Tufts New England Medical Center, Tufts University, Boston, MA, USA
    Circulation 112:3107-14. 2005
    ....
  87. doi request reprint Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry)
    James B Young
    Department of Cardiovascular Medicine, Heart Failure Section, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Am J Cardiol 101:223-30. 2008
    ..Lower hemoglobin is associated with higher morbidity and mortality in hospitalized patients with HF...
  88. ncbi request reprint Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design
    Gregg C Fonarow
    Department of Medicine, UCLA Medical Center, Los Angeles, Calif, USA
    Am Heart J 148:43-51. 2004
    ..The ultimate aim of this program is to improve the standard of HF care in the hospital and outpatient settings and increase the use of evidence-based therapeutic strategies to save lives...