D H Abbott

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Adaptations to subordinate status in female marmoset monkeys
    D H Abbott
    Wisconsin Regional Primate Research Center, Madison 53715 1299, USA
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 119:261-74. 1998
  2. pmc Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
    Rao Zhou
    National Primate Research Center, University of Wisconsin, Madison, WI 53715, United States
    Reprod Toxicol 23:438-48. 2007
  3. pmc Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood
    David H Abbott
    Department of Obstetrics and Gynecology and Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Fertil Steril 100:2-11. 2013
  4. pmc Nonhuman primate models of polycystic ovary syndrome
    David H Abbott
    Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI, USA
    Mol Cell Endocrinol 373:21-8. 2013
  5. pmc Fetal programming of adrenal androgen excess: lessons from a nonhuman primate model of polycystic ovary syndrome
    David H Abbott
    Department of Obstetrics and Gynecology, Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Endocr Dev 13:145-58. 2008
  6. pmc Contributions of androgen and estrogen to fetal programming of ovarian dysfunction
    David H Abbott
    National Primate Research Center, Department of Ob Gyn, Endocrinology Reproductive Physiology Training Program, University of Wisconsin, Madison, WI 53715, USA
    Reprod Biol Endocrinol 4:17. 2006
  7. pmc Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Am J Primatol 71:776-84. 2009
  8. pmc Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Biol Reprod 79:154-63. 2008
  9. pmc Experimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, USA
    Am J Physiol Endocrinol Metab 299:E741-51. 2010
  10. ncbi request reprint Gonadotrophin-releasing hormone (GnRH) release in marmosets II: pulsatile release of GnRH and pituitary gonadotrophin in adult females
    P L Tannenbaum
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI, USA
    J Neuroendocrinol 19:354-63. 2007

Research Grants

Collaborators

Detail Information

Publications54

  1. ncbi request reprint Adaptations to subordinate status in female marmoset monkeys
    D H Abbott
    Wisconsin Regional Primate Research Center, Madison 53715 1299, USA
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 119:261-74. 1998
    ..Such parallel developments probably reflect the outcome of repeated convergent evolutionary attempts at adapting to environmental conditions not readily conducive to dispersal and independent breeding...
  2. pmc Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
    Rao Zhou
    National Primate Research Center, University of Wisconsin, Madison, WI 53715, United States
    Reprod Toxicol 23:438-48. 2007
    ..To determine whether pioglitazone will improve menstrual cyclicity in a fetal programming model for polycystic ovary syndrome...
  3. pmc Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood
    David H Abbott
    Department of Obstetrics and Gynecology and Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Fertil Steril 100:2-11. 2013
    ..They raise the possibility for lifestyle or therapeutic intervention before and during pregnancy or during childhood and adolescence alleviating the manifestations of a familial genetic predisposition to PCOS...
  4. pmc Nonhuman primate models of polycystic ovary syndrome
    David H Abbott
    Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI, USA
    Mol Cell Endocrinol 373:21-8. 2013
    ..Acute T exposure of adult females generates polyfollicular ovaries, while chronic T exposure induces subtle menstrual irregularities without metabolic dysfunction...
  5. pmc Fetal programming of adrenal androgen excess: lessons from a nonhuman primate model of polycystic ovary syndrome
    David H Abbott
    Department of Obstetrics and Gynecology, Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Endocr Dev 13:145-58. 2008
    ..As adult prenatally androgenized female rhesus monkeys closely emulate PCOS-like symptoms, excess fetal androgen programming may contribute to adult adrenal androgen excess in women with PCOS...
  6. pmc Contributions of androgen and estrogen to fetal programming of ovarian dysfunction
    David H Abbott
    National Primate Research Center, Department of Ob Gyn, Endocrinology Reproductive Physiology Training Program, University of Wisconsin, Madison, WI 53715, USA
    Reprod Biol Endocrinol 4:17. 2006
    ..Understanding the quality of the fetal female sex steroid hormone environment is thus becoming increasingly important in improving our knowledge of mechanisms underlying a variety of female reproductive pathologies...
  7. pmc Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Am J Primatol 71:776-84. 2009
    ....
  8. pmc Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Biol Reprod 79:154-63. 2008
    ..Thus, in this nonhuman primate model, differential programming of the fetal hypothalamo-pituitary unit with concomitant hyperandrogenism provides evidence to suggest developmental origins of LH and androgen excess in adulthood...
  9. pmc Experimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring
    David H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, USA
    Am J Physiol Endocrinol Metab 299:E741-51. 2010
    ....
  10. ncbi request reprint Gonadotrophin-releasing hormone (GnRH) release in marmosets II: pulsatile release of GnRH and pituitary gonadotrophin in adult females
    P L Tannenbaum
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI, USA
    J Neuroendocrinol 19:354-63. 2007
    ....
  11. ncbi request reprint Insulin action during variable hyperglycemic-hyperinsulinemic infusions in hyperandrogenic anovulatory patients and healthy women
    D A Dumesic
    Department of Ob Gyn, Mayo Clinic, Rochester, Minnesota, USA
    Fertil Steril 72:458-66. 1999
    ....
  12. ncbi request reprint Pituitary desensitization to gonadotropin-releasing hormone increases abdominal adiposity in hyperandrogenic anovulatory women
    D A Dumesic
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota, USA
    Fertil Steril 70:94-101. 1998
    ..To determine whether hyperandrogenism in anovulatory women affects body fat distribution...
  13. ncbi request reprint Prenatal exposure of female rhesus monkeys to testosterone propionate increases serum luteinizing hormone levels in adulthood
    D A Dumesic
    Wisconsin Regional Primate Research Center, Madison, USA
    Fertil Steril 67:155-63. 1997
    ..To determine whether prenatal androgenization of the developing primate hypothalamohypophyseal unit induces irreversible changes in LH secretion...
  14. ncbi request reprint Suppression of cortisol levels in subordinate female marmosets: reproductive and social contributions
    W Saltzman
    Wisconsin Regional Primate Research Center, Endocrinology Reproductive Physiology Program, University of Wisconsin, Madison 53715 1299, USA
    Horm Behav 33:58-74. 1998
    ..Instead, other factors, such as direct effects of social subordination or suppression of LH levels, contribute to suppression of cortisol in subordinates...
  15. ncbi request reprint Novel restraint system for neuroendocrine studies of socially living common marmoset monkeys
    N J Schultz-Darken
    National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Lab Anim 38:393-405. 2004
    ....
  16. ncbi request reprint Reduced adrenocortical responsiveness to adrenocorticotropic hormone (ACTH) in socially subordinate female marmoset monkeys
    W Saltzman
    Wisconsin Regional Primate Research Center, University of Wisconsin Madison, Madison, WI 53715 1299, USA
    Psychoneuroendocrinology 25:463-77. 2000
    ..These results suggest that dampened adrenocortical responsiveness to ACTH contributes to chronic reductions in cortisol levels in subordinate female marmosets and may be mediated by suppression of reproductive hormones...
  17. pmc Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome
    C M Bruns
    Dean Clinic, Madison, WI, USA
    Int J Obes (Lond) 31:1579-85. 2007
    ....
  18. ncbi request reprint Developmental origin of polycystic ovary syndrome - a hypothesis
    D H Abbott
    Department of Obstetrics and Gynecology and Wisconsin Regional Primate Research Centre, University of Wisconsin, Madison 53715, USA
    J Endocrinol 174:1-5. 2002
    ..This hypothesis therefore suggests a unifying, 'linear' model to explain the aetiology of the heterogeneous phenotype...
  19. pmc Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys
    D A Dumesic
    National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Hum Reprod 24:3188-95. 2009
    ....
  20. ncbi request reprint Male marmoset monkeys express an adrenal fetal zone at birth, but not a zona reticularis in adulthood
    J Christina Pattison
    Perinatal Research Laboratories, University of Wisconsin Madison, Madison, Wisconsin 53715, USA
    Endocrinology 146:365-74. 2005
    ..We conclude that neonatal marmosets exhibit a C19 steroid-secreting FZ similar to humans, but adult males fail to acquire a functional ZR...
  21. ncbi request reprint Gonadotrophin-releasing hormone (GnRH) release in marmosets I: in vivo measurement in ovary-intact and ovariectomised females
    P L Tannenbaum
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI, USA
    J Neuroendocrinol 19:342-53. 2007
    ..Overall, these results indicate that PPP can be used to reliably assess in vivo GnRH release in marmosets and will be a useful tool for future studies of reproductive neuroendocrinology in this small primate...
  22. pmc Nonhuman primates as models for human adrenal androgen production: function and dysfunction
    D H Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Rev Endocr Metab Disord 10:33-42. 2009
    ....
  23. ncbi request reprint Reduced intrafollicular androstenedione and estradiol levels in early-treated prenatally androgenized female rhesus monkeys receiving follicle-stimulating hormone therapy for in vitro fertilization
    Daniel A Dumesic
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Biol Reprod 69:1213-9. 2003
    ....
  24. ncbi request reprint Early origins of polycystic ovary syndrome
    Daniel A Dumesic
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, 53715, USA
    Reprod Fertil Dev 17:349-60. 2005
    ..By doing so, future studies promise to develop new clinical strategies that will lead to improved pregnancy outcome and reduced pregnancy loss in women with disorders of insulin action, including PCOS, obesity and diabetes mellitus...
  25. ncbi request reprint Gonadotropin-releasing hormone II stimulates female sexual behavior in marmoset monkeys
    Deborah K Barnett
    National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Endocrinology 147:615-23. 2006
    ..These findings implicate a role for GnRH II and the cognate GnRH type II receptor in stimulating female marmoset sexual behavior...
  26. ncbi request reprint Ovarian hyperandrogenism in adult female rhesus monkeys exposed to prenatal androgen excess
    Joel R Eisner
    Wisconsin Regional Primate Research Center, University of Wisconsin Madison, 53715, USA
    Fertil Steril 77:167-72. 2002
    ..To determine whether there is an ovarian thecal cell component to hyperandrogenism exhibited in adult female rhesus monkeys exposed to androgen excess during prenatal life...
  27. pmc Adrenal hyperandrogenism is induced by fetal androgen excess in a rhesus monkey model of polycystic ovary syndrome
    Rao Zhou
    National Primate Research Center, University of Wisconsin, Madison 53715, USA
    J Clin Endocrinol Metab 90:6630-7. 2005
    ..Adrenal androgen excess is found in approximately 25-60% of women with polycystic ovary syndrome (PCOS), but the mechanisms underlying PCOS-related adrenal androgen excess are unclear...
  28. ncbi request reprint Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation
    Joel R Eisner
    Wisconsin Primate Research Center, Department of Obstetrics and Gynecology, Endocrinology Reproductive Physiology Program, University of Wisconsin, Madison, Wisconsin, USA
    Obes Res 11:279-86. 2003
    ..The aim of this study was to investigate the effects of early-gestational androgen excess on adult body fat distribution in female rhesus monkeys...
  29. ncbi request reprint Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys
    Cristin M Bruns
    Department of Medicine, University of Wisconsin, Madison, Wisconsin 53792, USA
    J Clin Endocrinol Metab 89:6218-23. 2004
    ..52, 711.89); P < 0.02]. PA males do not exhibit elevated androgens during adulthood, suggesting that insulin resistance and impaired pancreatic beta-cell function may result from fetal reprogramming of key metabolic tissues...
  30. ncbi request reprint Are subordinates always stressed? A comparative analysis of rank differences in cortisol levels among primates
    D H Abbott
    Department of Obstetrics Gynecology, University of Wisconsin, Madison, WI 53706, USA
    Horm Behav 43:67-82. 2003
    ....
  31. ncbi request reprint Impaired developmental competence of oocytes in adult prenatally androgenized female rhesus monkeys undergoing gonadotropin stimulation for in vitro fertilization
    Daniel A Dumesic
    Wisconsin Regional Primate Research Center, Department of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin 53715 1299, USA
    J Clin Endocrinol Metab 87:1111-9. 2002
    ..Early prenatal androgenization in monkeys receiving gonadotropins impairs oocyte developmental competence and seems to induce premature follicle differentiation in the presence of LH hypersecretion and relative insulin excess...
  32. pmc Polycystic ovary syndrome and its developmental origins
    Daniel A Dumesic
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Rev Endocr Metab Disord 8:127-41. 2007
    ....
  33. ncbi request reprint Insulin and messenger ribonucleic acid expression of insulin receptor isoforms in ovarian follicles from nonhirsute ovulatory women and polycystic ovary syndrome patients
    Jennifer L Phy
    Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Clin Endocrinol Metab 89:3561-6. 2004
    ..Granulosa cell IR heterogeneity, together with adiposity-dependent intrafollicular insulin availability, introduces a novel mechanism by which insulin may affect granulosa cell function within the follicle...
  34. ncbi request reprint Reproductive adaptations to a large-brained fetus open a vulnerability to anovulation similar to polycystic ovary syndrome
    Deborah K Barnett
    Wisconsin Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Am J Hum Biol 15:296-319. 2003
    ....
  35. ncbi request reprint Nonhuman primates contribute unique understanding to anovulatory infertility in women
    David H Abbott
    Department of Obstetrics and Gynecology, and UW Madison National Primate Research Center, University of Wisconsin, Madison, USA
    ILAR J 45:116-31. 2004
    ....
  36. pmc Implications of polycystic ovary syndrome on oocyte development
    Daniel A Dumesic
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USA
    Semin Reprod Med 26:53-61. 2008
    ....
  37. pmc Gender and gonadal status differences in zona reticularis expression in marmoset monkey adrenals: Cytochrome b5 localization with respect to cytochrome P450 17,20-lyase activity
    J Christina Pattison
    Perinatal Research Laboratories, University of Wisconsin Madison, Madison, WI 53715, USA
    Mol Cell Endocrinol 265:93-101. 2007
    ....
  38. doi request reprint Plasticity of the zona reticularis in the adult marmoset adrenal cortex: voyages of discovery in the New World
    J Christina Pattison
    Perinatal Research Laboratories, University of Wisconsin Madison, 7E Meriter Hospital Park, 202 South Park Street, Madison, Wisconsin 53715, USA
    J Endocrinol 203:313-26. 2009
    ..We propose that these combined data from the marmoset model provide further compelling evidence that the control of ZR CYTB5 expression is a key determinant of ZR function...
  39. pmc Polycystic ovary syndrome and oocyte developmental competence
    Daniel A Dumesic
    Department of Obstetrics and Gynecology, Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USA
    Obstet Gynecol Surv 63:39-48. 2008
    ....
  40. ncbi request reprint Aspects of common marmoset basic biology and life history important for biomedical research
    David H Abbott
    Wisconsin Primate Research Center, Department of Ob Gyn, University of Wisconsin, 1223 Capitol Court, Madison, Wisconsin 53715, USA
    Comp Med 53:339-50. 2003
    ..These differences, however, permit the use of common marmosets in unconventional research strategies targeted on human pathology...
  41. ncbi request reprint Diminished intrafollicular estradiol levels in in vitro fertilization cycles from women with reduced ovarian response to recombinant human follicle-stimulating hormone
    Shu C Foong
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Fertil Steril 83:1377-83. 2005
    ..To correlate serum and intrafollicular E(2) levels in women receiving GnRH agonist and recombinant human (h)FSH for IVF...
  42. ncbi request reprint Increased adiposity enhances intrafollicular estradiol levels in normoandrogenic ovulatory women receiving gonadotropin-releasing hormone analog/recombinant human follicle-stimulating hormone therapy for in vitro fertilization
    Daniel A Dumesic
    National Primate Research Center, University of Wisconsin, Madison 53715, USA
    J Clin Endocrinol Metab 92:1438-41. 2007
    ..Body mass index (BMI) reflects the amount of insulin in the human follicle and may enhance insulin action as a cogonadotropin...
  43. ncbi request reprint Diminished maternal responsiveness during pregnancy in multiparous female common marmosets
    Wendy Saltzman
    Department of Biology, University of California, Riverside, CA 92521, USA
    Horm Behav 47:151-63. 2005
    ..These results suggest that maternal responsiveness in marmosets may be attenuated during pregnancy, especially late pregnancy, and this may contribute to infanticide by breeding females...
  44. ncbi request reprint Social suppression of cortisol in female marmosets: role of luteinizing hormone/chorionic gonadotropin
    Wendy Saltzman
    Department of Biology, University of California Riverside, Riverside, CA 92521, USA
    Gen Comp Endocrinol 149:90-9. 2006
    ..Thus, suppression of CG release in anovulatory subordinate females may not play an important role in socially induced diminution of cortisol...
  45. ncbi request reprint Purification and characterization of a novel intracellular 17 beta-estradiol binding protein in estrogen-resistant New World primate cells
    Hong Chen
    Division of Endocrinology, Diabetes and Metabolism, Cedars Sinai Burns and Allen Research Institute, UCLA School of Medicine, Los Angeles, California, USA
    J Clin Endocrinol Metab 88:501-4. 2003
    ..In conclusion, IEBP is a specific E2-interacting heat shock protein in the hsp-27 family that is relatively overexpressed in estrogen-resistant cells...
  46. ncbi request reprint Reproductive output, maternal age, and survivorship in captive common marmoset females (Callithrix jacchus)
    Darlene A Smucny
    Southwest National Primate Research Center, San Antonio, Texas 78245 0549, USA
    Am J Primatol 64:107-21. 2004
    ..e., dams that delayed first reproduction had higher survival. Our findings about reproductive variation in marmosets may have practical applications for the management of marmoset breeding colonies...
  47. ncbi request reprint Human adenovirus Ad-36 promotes weight gain in male rhesus and marmoset monkeys
    Nikhil V Dhurandhar
    Department of Nutrition and Food Science and the Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA
    J Nutr 132:3155-60. 2002
    ..These studies illustrate that the adiposity-promoting effect of Ad-36 occurs in two nonhuman primate species and demonstrates the usefulness of nonhuman primates for further evaluation of Ad-36-induced adiposity...
  48. ncbi request reprint Cutting edge: inhibiting measles virus infection but promoting reproduction: an explanation for splicing and tissue-specific expression of CD46
    Rebecca C Riley
    Division of Rheumatology, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Immunol 169:5405-9. 2002
    ..In these species, sperm express MCP bearing CCP1. The germ cell-specific expression pattern of this domain strongly suggests an evolutionarily conserved role for MCP in fertilization...
  49. ncbi request reprint Diminished cortisol levels in subordinate female marmosets are associated with altered central drive to the hypothalamic-pituitary-adrenal axis
    Wendy Saltzman
    Department of Biology and Neuroscience Graduate Program, University of California, Riverside, California 92521, USA
    Biol Psychiatry 60:843-9. 2006
    ....
  50. ncbi request reprint Follicle luteinization in hyperandrogenic follicles of polycystic ovary syndrome patients undergoing gonadotropin therapy for in vitro fertilization
    Shu C Foong
    Reproductive Medicine and Infertility Associates, 2101 Woodwinds Drive, Woodbury, Minnesota 55125, USA
    J Clin Endocrinol Metab 91:2327-33. 2006
    ..After exposure to GnRH analog/FSH stimulation for in vitro fertilization (IVF), however, it is unclear whether such PCOS follicles remain abnormally luteinized during the resumption of oocyte maturation in vivo...
  51. ncbi request reprint Hypoestrogenism does not mediate social suppression of cortisol in subordinate female marmosets
    Wendy Saltzman
    Department of Biology, University of California, Riverside, CA 92521, USA
    Psychoneuroendocrinology 31:692-702. 2006
    ....
  52. ncbi request reprint Molecular abnormalities in oocytes from women with polycystic ovary syndrome revealed by microarray analysis
    Jennifer R Wood
    Department of Animal Science, University of Nebraska Lincoln, 3800 Fair Street, Lincoln, Nebraska 68583 0908, USA
    J Clin Endocrinol Metab 92:705-13. 2007
    ..These PCOS phenotypes are associated with exaggerated ovarian responsiveness to FSH and increased pregnancy loss...
  53. ncbi request reprint Post-conception reproductive competition in cooperatively breeding common marmosets
    Wendy Saltzman
    Department of Biology, University of California, Riverside, CA 92521, USA
    Horm Behav 53:274-86. 2008
    ..Our findings further suggest that infanticide by breeding females may have selected for the evolution of reproductive restraint in subordinate female marmosets...
  54. ncbi request reprint Reproduction in captive common marmosets (Callithrix jacchus)
    Suzette D Tardif
    Southwest National Primate Research Center, Post Office Box 760549, San Antonio, Texas 78245 0549, USA
    Comp Med 53:364-8. 2003
    ..A brief comparison between marmoset and tamarin reproduction also will be provided...

Research Grants4

  1. ANDROGENIZED FEMALE AS A MODEL FOR P0LYCYSTIC OVARIAN SY
    David Abbott; Fiscal Year: 2002
    ..Such results would offer novel insights into the origin and mechanism of PCOS, and would provide a unifying determinant for a multifactorial syndrome. ..