Jan E Aagaard

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Duplicate abalone egg coat proteins bind sperm lysin similarly, but evolve oppositely, consistent with molecular mimicry at fertilization
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, Seattle, Washington, USA
    PLoS Genet 9:e1003287. 2013
  2. pmc ZP domain proteins in the abalone egg coat include a paralog of VERL under positive selection that binds lysin and 18-kDa sperm proteins
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:193-203. 2010
  3. pmc Rapidly evolving zona pellucida domain proteins are a major component of the vitelline envelope of abalone eggs
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, Box 357730, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:17302-7. 2006
  4. pmc The molecular basis of sex: linking yeast to human
    Willie J Swanson
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 28:1963-6. 2011
  5. ncbi request reprint Relaxed selection among duplicate floral regulatory genes in Lamiales
    Jan E Aagaard
    Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, OR 97403, USA
    J Mol Evol 63:493-503. 2006
  6. doi request reprint Functional diversification and evolution of antifreeze proteins in the antarctic fish Lycodichthys dearborni
    Joanna L Kelley
    Department of Genome Sciences, University of Washington, Seattle, WA, USA
    J Mol Evol 71:111-8. 2010
  7. ncbi request reprint Evolution of reproductive proteins from animals and plants
    Nathaniel L Clark
    Department of Genome Sciences, University of Washington, Box 357730, Seattle, USA
    Reproduction 131:11-22. 2006

Detail Information

Publications7

  1. pmc Duplicate abalone egg coat proteins bind sperm lysin similarly, but evolve oppositely, consistent with molecular mimicry at fertilization
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, Seattle, Washington, USA
    PLoS Genet 9:e1003287. 2013
    ..We describe a model of sexual conflict that can recreate this pattern of anti-correlated evolution by assuming that VEZP14 acts as a VERL mimic, reducing the intensity of sexual conflict and slowing the co-evolution of lysin and VERL...
  2. pmc ZP domain proteins in the abalone egg coat include a paralog of VERL under positive selection that binds lysin and 18-kDa sperm proteins
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 27:193-203. 2010
    ..This work identifies an egg coat paralog of VERL under positive selection and the candidate sperm proteins with which it may interact during abalone fertilization...
  3. pmc Rapidly evolving zona pellucida domain proteins are a major component of the vitelline envelope of abalone eggs
    Jan E Aagaard
    Department of Genome Sciences, University of Washington, Box 357730, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 103:17302-7. 2006
    ..This work provides further evidence of the prominence of ZP proteins as constituents of the egg coat, as well as the prominent role of positive selection in diversification of these reproductive proteins...
  4. pmc The molecular basis of sex: linking yeast to human
    Willie J Swanson
    Department of Genome Sciences, University of Washington, USA
    Mol Biol Evol 28:1963-6. 2011
    ..6-1 billion years of evolution, functionally essential domains of a mollusc sperm receptor and a yeast mating protein adopt the same 3D fold as egg zona pellucida proteins mediating the binding between gametes in humans...
  5. ncbi request reprint Relaxed selection among duplicate floral regulatory genes in Lamiales
    Jan E Aagaard
    Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, OR 97403, USA
    J Mol Evol 63:493-503. 2006
    ..Several mechanisms are discussed that might be responsible for preservation of co-orthologs of FLO and DEF in Lamiales, including interactions among the genes of this regulatory pathway...
  6. doi request reprint Functional diversification and evolution of antifreeze proteins in the antarctic fish Lycodichthys dearborni
    Joanna L Kelley
    Department of Genome Sciences, University of Washington, Seattle, WA, USA
    J Mol Evol 71:111-8. 2010
    ..Our molecular evolution study shows that paralogs have diverged under positive selection. We hypothesize that antifreeze protein diversity is an important contributor to depressing the serum freezing point...
  7. ncbi request reprint Evolution of reproductive proteins from animals and plants
    Nathaniel L Clark
    Department of Genome Sciences, University of Washington, Box 357730, Seattle, USA
    Reproduction 131:11-22. 2006
    ....