Marina N Torrero

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. pmc CD200R surface expression as a marker of murine basophil activation
    M N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Clin Exp Allergy 39:361-9. 2009
  2. doi request reprint Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 185:7426-34. 2010
  3. pmc Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA
    J Immunol 188:4188-99. 2012
  4. pmc Type 2 immune-inducing helminth vaccination maintains protective efficacy in the setting of repeated parasite exposures
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Vaccine 28:1746-57. 2010
  5. doi request reprint Vaccination with intestinal tract antigens does not induce protective immunity in a permissive model of filariasis
    C Paul Morris
    Department of Microbiology and Immunology, F Edward Hebert School of Medicine, Uniformed Services University of Health Sciences, Bethesda, MD 20852, USA
    Exp Parasitol 135:87-95. 2013
  6. pmc Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Vaccine 31:3675-82. 2013
  7. pmc Chronic helminth infection does not exacerbate Mycobacterium tuberculosis infection
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
    PLoS Negl Trop Dis 6:e1970. 2012
  8. pmc Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 188:559-68. 2012
  9. pmc Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice
    Marc P Hübner
    Dept of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Clin Immunol 141:205-17. 2011
  10. pmc Induction of type 2 responses by schistosome worms during prepatent infection
    Lucia Alves de Oliveira Fraga
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    J Infect Dis 201:464-72. 2010

Collaborators

Detail Information

Publications11

  1. pmc CD200R surface expression as a marker of murine basophil activation
    M N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Clin Exp Allergy 39:361-9. 2009
    ..One of the main obstacles to studying basophils has been the lack of a simple and rapid assay to measure basophil activation in mice...
  2. doi request reprint Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 185:7426-34. 2010
    ..These results demonstrate that basophils amplify type 2 immune responses, but do not serve a protective role, in chronic infection of mice with the filarial nematode L. sigmodontis...
  3. pmc Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA
    J Immunol 188:4188-99. 2012
    ....
  4. pmc Type 2 immune-inducing helminth vaccination maintains protective efficacy in the setting of repeated parasite exposures
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Vaccine 28:1746-57. 2010
    ..These results demonstrate that vaccines which induce type 2 immune responses can maintain their efficacy in the setting of repeated parasite exposures...
  5. doi request reprint Vaccination with intestinal tract antigens does not induce protective immunity in a permissive model of filariasis
    C Paul Morris
    Department of Microbiology and Immunology, F Edward Hebert School of Medicine, Uniformed Services University of Health Sciences, Bethesda, MD 20852, USA
    Exp Parasitol 135:87-95. 2013
    ..sigmodontis have some qualities of 'hidden' antigens, but they still sensitize mice to allergic reactions and fail to protect against future infection when given as a vaccine adsorbed to alum/CPG...
  6. pmc Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Vaccine 31:3675-82. 2013
    ..These findings demonstrate that basophils help establish the immune responses responsible for irradiated L3 vaccine protection. ..
  7. pmc Chronic helminth infection does not exacerbate Mycobacterium tuberculosis infection
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
    PLoS Negl Trop Dis 6:e1970. 2012
    ..As both of these responses can suppress Th1 immunity, which is necessary for control of Mycobacterium tuberculosis (MTB) infection, we hypothesized that chronic helminth infections may exacerbate the course of MTB...
  8. pmc Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 188:559-68. 2012
    ..This study demonstrates that L. sigmodontis-mediated protection against diabetes in NOD mice is not dependent on the induction of a type 2 immune shift but does require TGF-β...
  9. pmc Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice
    Marc P Hübner
    Dept of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Clin Immunol 141:205-17. 2011
    ..These results demonstrate that anti-FcεR1 therapy delays diabetes onset in NOD mice and suggest that chronic basophil and mast cell activation may represent a new avenue of therapy for Th1-associated autoimmune diseases...
  10. pmc Induction of type 2 responses by schistosome worms during prepatent infection
    Lucia Alves de Oliveira Fraga
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    J Infect Dis 201:464-72. 2010
    ....
  11. pmc Litomosoides sigmodontis: a simple method to infect mice with L3 larvae obtained from the pleural space of recently infected jirds (Meriones unguiculatus)
    Marc P Hübner
    Dept of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Exp Parasitol 123:95-8. 2009
    ..Additionally, this method allows for geographical separation of the facility maintaining the L. sigmodontis life cycle from the institution at which mice are infected...