Venkataraman Srinivasan

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. ncbi Radioprotection, pharmacokinetic and behavioural studies in mouse implanted with biodegradable drug (amifostine) pellets
    V Srinivasan
    Radiation Casualty Management Team, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Int J Radiat Biol 78:535-43. 2002
  2. ncbi Evaluation of EUK-189, a synthetic superoxide dismutase/catalase mimetic as a radiation countermeasure
    Venkataraman Srinivasan
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Bethesda, Maryland Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    Immunopharmacol Immunotoxicol 30:271-90. 2008
  3. ncbi Genistein treatment protects mice from ionizing radiation injury
    Michael R Landauer
    Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    J Appl Toxicol 23:379-85. 2003
  4. ncbi Radioprotection by N-palmitoylated nonapeptide of human interleukin-1beta
    Vijay K Singh
    Radiation Casualty Management Team, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    Peptides 26:413-8. 2005
  5. ncbi A TPO receptor agonist, ALXN4100TPO, mitigates radiation-induced lethality and stimulates hematopoiesis in CD2F1 mice
    Merriline Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University, Bethesda, Maryland 20889 USA
    Radiat Res 175:746-58. 2011
  6. ncbi Determination of WR-1065 and WR-33278 by liquid chromatography with electrochemical detection
    James A Pendergrass
    Armed Forces Radiobiology Research Institute, Radiation Medicine Department, Bethesda, MD 20889 5603, USA
    J AOAC Int 85:551-4. 2002
  7. ncbi Protection against gamma-irradiation with 5-androstenediol
    Mark H Whitnall
    Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
    Mil Med 167:64-5. 2002
  8. ncbi New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel
    Thomas Seed
    Radiation Casualty Management, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    J Radiat Res 43:S239-44. 2002
  9. ncbi Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol
    Merriline M Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 175:736-45. 2011
  10. ncbi Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling
    Xiang Hong Li
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, 8901 Wisconsin Ave, Bethesda, MD 20889 5603, USA
    Haematologica 95:1996-2004. 2010

Collaborators

Detail Information

Publications12

  1. ncbi Radioprotection, pharmacokinetic and behavioural studies in mouse implanted with biodegradable drug (amifostine) pellets
    V Srinivasan
    Radiation Casualty Management Team, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Int J Radiat Biol 78:535-43. 2002
    ..We evaluated the use of a subcutaneously (s.c.) implantable, biodegradable pellet as a drug delivery system for the radioprotector amifostine...
  2. ncbi Evaluation of EUK-189, a synthetic superoxide dismutase/catalase mimetic as a radiation countermeasure
    Venkataraman Srinivasan
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Bethesda, Maryland Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    Immunopharmacol Immunotoxicol 30:271-90. 2008
    ..EUK-189 did not stimulate production of any cytokine or chemokine tested...
  3. ncbi Genistein treatment protects mice from ionizing radiation injury
    Michael R Landauer
    Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    J Appl Toxicol 23:379-85. 2003
    ..These results demonstrate that a single s.c. administration of the flavonoid genistein at non-toxic doses provides protection against acute radiation injury...
  4. ncbi Radioprotection by N-palmitoylated nonapeptide of human interleukin-1beta
    Vijay K Singh
    Radiation Casualty Management Team, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    Peptides 26:413-8. 2005
    ..These results suggest the importance of the derivatization of small peptides of radioprotective, but toxic cytokines in order to enhance radioprotective activity while reducing unwanted toxic side effects...
  5. ncbi A TPO receptor agonist, ALXN4100TPO, mitigates radiation-induced lethality and stimulates hematopoiesis in CD2F1 mice
    Merriline Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University, Bethesda, Maryland 20889 USA
    Radiat Res 175:746-58. 2011
    ....
  6. ncbi Determination of WR-1065 and WR-33278 by liquid chromatography with electrochemical detection
    James A Pendergrass
    Armed Forces Radiobiology Research Institute, Radiation Medicine Department, Bethesda, MD 20889 5603, USA
    J AOAC Int 85:551-4. 2002
    ..Within- and between-day determinations of measurement Vision and accuracy for both compounds validated the suitability of this assay method...
  7. ncbi Protection against gamma-irradiation with 5-androstenediol
    Mark H Whitnall
    Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
    Mil Med 167:64-5. 2002
    ..Clinical chemistry, histopathology, and behavioral assays showed no evidence of toxicity. We conclude that AED and related steroids are attractive candidates to explore as countermeasures to high- and low-level ionizing radiation...
  8. ncbi New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel
    Thomas Seed
    Radiation Casualty Management, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    J Radiat Res 43:S239-44. 2002
    ....
  9. ncbi Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol
    Merriline M Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 175:736-45. 2011
    ..05). The large therapeutic potential of and multi-lineage hematopoietic recovery for DT3 warrants further studies...
  10. ncbi Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling
    Xiang Hong Li
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, 8901 Wisconsin Ave, Bethesda, MD 20889 5603, USA
    Haematologica 95:1996-2004. 2010
    ..We explored the effects and mechanisms of δ-tocotrienol on hematopoietic progenitor cell survival after γ-irradiation in both in vivo and in vitro experiments...
  11. ncbi Nutritional approaches to radioprotection: vitamin E
    K Sree Kumar
    Radiation Casualty Management Research Team, Department of Radiation Medicine, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Besthesda, MD 20889-5603, USA
    Mil Med 167:57-9. 2002
    ..Vitamin E was more efficacious when given subcutaneously than when given orally...
  12. ncbi Oral delivery of spray dried PLGA/amifostine nanoparticles
    Sarala Pamujula
    College of Pharmacy, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA 70125-1098, USA
    J Pharm Pharmacol 56:1119-25. 2004
    ..This work demonstrates the feasibility of developing an orally effective formulation of amifostine that can be used clinically...