Research Topics
Species | A SinghSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Differential hypothalamic-pituitary-adrenal axis reactivity to psychological and physical stressA Singh
Department of Military and Emergency Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
J Clin Endocrinol Metab 84:1944-8. 1999..This suggests that the adrenal cortexes of the HR are hypertropic and/or hypersensitive to ACTH. We conclude that men who are highly responsive to exercise stress are also highly responsive to psychological stress...
High intensity exercise promotes escape of adrenocorticotropin and cortisol from suppression by dexamethasone: sexually dimorphic responsesP A Deuster
Department of Military and Emergency Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
J Clin Endocrinol Metab 83:3332-8. 1998....
Neuroendocrine responses to running in women after zinc and vitamin E supplementationA Singh
Department of Military and Emergency Medicine, Uniformed Services University of the Health Sciences, and Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20814 4799, USA
Med Sci Sports Exerc 31:536-42. 1999..The study was undertaken to determine whether acute supplementation with zinc or vitamin E would modify neuroendocrine responses to physiologic stress...
Expression of lymphocyte subsets after exercise and dexamethasone in high and low stress respondersP A Deuster
Department of Military and Emergency Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814 4799, USA
Med Sci Sports Exerc 31:1799-806. 1999..We studied whether differential activation of the HPA axis affected cytokine production and expression of selected lymphocyte subsets in HR and LR in response to high-intensity exercise after placebo and dexamethasone (DEX; 4 mg)...
Endocrine response to high-intensity exercise: dose-dependent effects of dexamethasoneP A Deuster
Department of Military and Emergency Medicine, Uniformed Services, University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
J Clin Endocrinol Metab 85:1066-73. 2000..The question of whether these differences in reactivity of the ACTH-cortisol axis between the HR and LR groups have implications for individual short term function or long term health remains to be answered...
IL-6 protects enterocytes from hypoxia-induced apoptosis by induction of bcl-2 mRNA and reduction of fas mRNAF M Rollwagen
Department of Pathology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Biochem Biophys Res Commun 347:1094-8. 2006..RNase protection assay (RPA) examination revealed that under hypoxic conditions, IEC-6 cells that were resistant to apoptosis showed reduced fas expression and increased bcl-2 expression after co-culture with LPS+IL-6...
Peptide inhibition of cytokine-stimulated aromatase activity in breast tissue fibroblastsD Parish
Endocrinology and Metabolic Medicine, Imperial College School of Medicine, St Mary s Hospital, W2 1NY, London, UK
J Steroid Biochem Mol Biol 79:165-72. 2001..Results from this study suggest that it may be possible to develop small peptides to inhibit cytokine-stimulated aromatase activity in a tissue-specific manner...
Inhibition of IL-6+IL-6 soluble receptor-stimulated aromatase activity by the IL-6 antagonist, Sant 7, in breast tissue-derived fibroblastsA Purohit
Endocrinology and Metabolic Medicine, Faculty of Medicine, Imperial College, St Mary s Hospital, London, UK
Br J Cancer 88:630-5. 2003..The ability to block aromatase stimulation by these factors may offer a novel therapeutic strategy for reducing oestrogen synthesis in breast tumours...
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancerA Singh
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi-110029, India
Pathobiology 71:314-22. 2004..Additionally, newer proteins such as p73 may play a compensatory role for the nonfunctional proteins such as p53...
Lipopolysaccharide-mediated immobility in mice: reversal by cyclooxygenase enzyme inhibitorsN K Jain
Pharmacology Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
Methods Find Exp Clin Pharmacol 23:441-4. 2001..The present study demonstrated that LPS-induced inflammatory responses in the brain may cause despair behavior. Reversal with a cyclooxygenase inhibitor indicates the role of prostaglandins in despair behavior...
