Research Topics
Species | Anuj SharmaSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brainAnuj Sharma
Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
BMC Genomics 9:289. 2008..Changes in gene expression were correlated with histological changes in the brain. In addition, a molecular framework of changes in gene expression associated with progression of the disease was studied...
Homeopathic medicines do not alter growth and gene expression in prostate and breast cancer cells in vitroRajesh L Thangapazham
Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Integr Cancer Ther 5:356-61. 2006..CONCLUSIONS: The results demonstrate that the highly diluted homeopathic remedies used by homeopathic practitioners for cancer show no measurable effects on cell growth or gene expression in vitro using currently available methodologies...
Picroliv accelerates epithelialization and angiogenesis in rat woundsAnoop K Singh
Center for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Life Sciences, Bethesda, Maryland 20814, USA
Planta Med 73:251-6. 2007..These findings suggest that picroliv could be developed as a therapeutic angiogenic agent for the restoration of the blood supply in diseases involving inadequate blood supply such as limb ischemia, ischemic myocardium and wound healing...
Inhibition of tumor angiogenesis by Brahma Rasayana (BR)Rajesh L Thangapazham
Department of Pathology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
J Exp Ther Oncol 6:13-21. 2006..These findings suggest the possible mechanism(s) of action of BR in the reduction of tumor growth and metastatic spread...
Safety and protective efficacy of INA-inactivated Venezuelan equine encephalitis virus: implication in vaccine developmentAnuj Sharma
Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Vaccine 29:953-9. 2011..Results suggest that inactivation of enveloped viruses by INA may occur by two independent mechanisms and the INA-inactivated VEEV elicit a protective antibody response in mice...
Beneficial role of curcumin in skin diseasesRajesh L Thangapazham
Uniformed Services University of Health Sciences, Bethesda, MD, USA
Adv Exp Med Biol 595:343-57. 2007..These studies suggest the beneficial effects of curcumin and the potential of this compound to be developed as a potent nontoxic agent for treating skin diseases...
Role of adhesion molecules and inflammation in Venezuelan equine encephalitis virus infected mouse brainAnuj Sharma
Dept of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Virol J 8:197. 2011..In this study, we evaluated the expression of extracellular matrix and adhesion molecules genes in the brain of VEEV infected mice...
Oligonucleotide array analysis of Toll-like receptors and associated signalling genes in Venezuelan equine encephalitis virus-infected mouse brainAnuj Sharma
Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
J Gen Virol 90:1836-47. 2009..These results demonstrate the upregulation of TLRs and associated signalling genes following VEEV infection of the brain, with important implications for how VEEV induces inflammation and neurodegeneration...
Effect of homeopathic treatment on gene expression in Copenhagen rat tumor tissuesRajesh L Thangapazham
Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Integr Cancer Ther 5:350-5. 2006..Future research should explore subtle modulations in the expression of multiple genes in different biological pathways...
Preserving immunogenicity of lethally irradiated viral and bacterial vaccine epitopes using a radio- protective Mn2+-Peptide complex from DeinococcusElena K Gaidamakova
Department of Pathology, School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Cell Host Microbe 12:117-24. 2012..This approach could expedite vaccine production for emerging and established pathogens for which no protective vaccines exist...
Analysis of microRNAs induced by Venezuelan equine encephalitis virus infection in mouse brainManish Bhomia
Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Biochem Biophys Res Commun 395:11-6. 2010..Target gene prediction of the modulated miRNAs correlates with our recently reported mRNA expression in VEEV infected mice brain...
Differential regulation of angiogenic genes in diabetic wound healingAnuj Sharma
Department of Pathology, Center for Combat Casualty and Life Sustainment Research, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Invest Dermatol 126:2323-31. 2006..This finding suggests that OPN might be playing a crucial role in the early events of the wound healing and its delayed expression may be in part responsible for the delayed healing of wounds in diabetic mice...
Multiple molecular targets in cancer chemoprevention by curcuminRajesh L Thangapazham
Department of Pathology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
AAPS J 8:E443-9. 2006..This review summarizes the inhibition of NF-kappaB by curcumin and describes the recently identified molecular targets of curcumin. It is hoped that continued research will lead to development of curcumin as an anticancer agent...
Complete inactivation of Venezuelan equine encephalitis virus by 1,5-iodonaphthylazideAnuj Sharma
Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Biochem Biophys Res Commun 358:392-8. 2007..This data suggest that such inactivation strategies can be used for developing vaccine candidates for VEEV and other enveloped viruses...
Can homeopathic treatment slow prostate cancer growth?Wayne B Jonas
Samueli Institute, 1700 Diagonal Road, Suite 400, Alexandria, VA 22314, USA
Integr Cancer Ther 5:343-9. 2006..Therefore, the authors conducted a series of carefully controlled laboratory studies evaluating the effects of commonly used homeopathic remedies in cell and animal models of prostate cancer...
