Research Topics
Species | Ann I ScherSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Hippocampal morphometry in population-based incident Alzheimer's disease and vascular dementia: the HAASAnn I Scher
Uniformed Services University, Department of Preventive Medicine and Biometrics, 4301 Jones Bridge Road Bethesda, Maryland 20814, USA
J Neurol Neurosurg Psychiatry 82:373-6. 2011..Hippocampal changes may be a useful biomarker for Alzheimer's disease if they are specific to dementia sub-type. We compare hippocampal volume and shape in population-based incident cases of Alzheimer's disease and vascular dementia (VaD)...
Hippocampal shape analysis in Alzheimer's disease: a population-based studyA I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD 20814, USA
Neuroimage 36:8-18. 2007..In this study, we use structural imaging techniques to model hippocampal size and regional shape differences between elderly men with incident AD and a non-demented comparison group of elderly men...
Patterns of medication use by chronic and episodic headache sufferers in the general population: results from the frequent headache epidemiology studyA I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD 20814, USA
Cephalalgia 30:321-8. 2010..4-0.9)]. After adjusting for demographic factors, primary headache type and number of medications taken, CDH sufferers are more likely to use opioid-combination analgesics, and less likely to use aspirin or ibuprofen, than EH sufferers...
Migraine and MTHFR C677T genotype in a population-based sampleAnn I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD 20814 4799, USA
Ann Neurol 59:372-5. 2006..We assessed the association of the MTHFR C677T variant with migraine and the mediating effect of cardiovascular risk factors and metabolic markers of genotype status...
Comorbidity of migraineAnn I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
Curr Opin Neurol 18:305-10. 2005..Thus, estimates of the burden of migraine often include the costs of conditions comorbid with it...
Cardiovascular risk factors and migraine: the GEM population-based studyA I Scher
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
Neurology 64:614-20. 2005..In this study, the authors compare the cardiovascular risk profile of adult migraineurs to that of nonmigraineurs...
MTHFR C677T genotype as a risk factor for epilepsy including post-traumatic epilepsy in a representative military cohortAnn I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, Maryland 20814, USA
J Neurotrauma 28:1739-45. 2011..Further exploration of baseline homocysteine and folate levels as predictors of seizure risk following traumatic brain injury is warranted...
Caffeine as a risk factor for chronic daily headache: a population-based studyAnn I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
Neurology 63:2022-7. 2004..To investigate the possible association of dietary caffeine consumption and medicinal caffeine use with chronic daily headache (CDH)...
Chronic pain disorders and headache chronificationThomas McFate
Department of Preventive Medicine and Biometrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Curr Pain Headache Rep 13:308-13. 2009..We also consider the limitations and methodological challenges in understanding how two different chronic pain disorders may be related...
Major life changes before and after the onset of chronic daily headache: a population-based studyA I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD, USA
Cephalalgia 28:868-76. 2008..33 (1.2, 1.50) vs. OR 1.04 (0.9, 1.2), P < 0.05 for interaction by age]. These results suggest that major life changes are associated with the onset of chronic daily headache, particularly in middle age...
Lack of association between the MTHFR C677T variant and migraine with aura in an older population: could selective survival play a role?Ann I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Cephalalgia 33:308-15. 2013..Here, we consider whether this variant is associated with MA risk in an older non-clinical population (AGES-Reykjavik cohort)...
Analysis and validation of automated skull stripping tools: a validation study based on 296 MR images from the Honolulu Asia aging studyS W Hartley
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
Neuroimage 30:1179-86. 2006..Although method accuracy was statistically associated with some subject characteristics, the extent of the misclassification (in terms of percent of brain volume) was small...
The epidemiology of chronic daily headacheLynn A Midgette
Department of Preventive Medicine and Biometrics, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814 4799, USA
Curr Pain Headache Rep 13:59-63. 2009..Understanding the factors that put people at risk for developing CDH helps to inform possible clinical interventions and also determines which individuals may be most in need of preventive efforts...
Risk factors for headache chronificationAnn I Scher
Uniformed Services University Preventive Medicine Biometrics, Bethesda, MD 20814, USA
Headache 48:16-25. 2008..This review summarizes the evidence from population-based studies related to the chronic daily headache phenotype, natural history, and risk factors that may influence incidence, prevalence, or prognosis...
Migraine headache in middle age and late-life brain infarctsAnn I Scher
Uniformed Services University, Bethesda, Maryland, USA
JAMA 301:2563-70. 2009..Migraine is considered to be an episodic condition with no long-term consequences. However, recent studies suggest that migraine attacks may be associated with pathologic changes in the brain, particularly in the cerebellum...
The comorbidity of headache with other pain syndromesAnn I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD 20814, USA
Headache 46:1416-23. 2006..We consider exogenous and endogenous factors, and methodological challenges, in understanding whether and how 2 pain conditions may be related...
Habitual snoring as a risk factor for chronic daily headacheA I Scher
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 9205, USA
Neurology 60:1366-8. 2003..9; p < 0.005). If this association proves causal, sleep-disordered breathing may provide a target for therapeutic interventions for chronic daily headache...
Dementia resulting from traumatic brain injury: what is the pathology?Sharon Shively
Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Arch Neurol 69:1245-51. 2012..Herein, we will review the epidemiologic data linking TBI and dementia, existing clinical and pathologic data, and will identify areas where future research is needed...
Risk factors for chronic daily headacheAnn I Scher
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Avenue, MSC 9205, Bethesda, MD 20892 9205, USA
Curr Pain Headache Rep 6:486-91. 2002..In this manuscript, we review clinic-based data on risk factors for chronic daily headache and summarize the current data on the epidemiology of chronic daily headache...
Factors associated with the onset and remission of chronic daily headache in a population-based studyA I Scher
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Gateway Building, Suite 3C 309, 7201 Wisconsin Avenue, MSC 9205, Bethesda, MD 20892 9205, USA
Pain 106:81-9. 2003..New onset CDH was associated with baseline headache frequency and obesity...
Head or neck injury increases the risk of chronic daily headache: a population-based studyLars J Stovner
Neurology 71:383-5. 2008
Age effects on hippocampal structural changes in old men: the HAASYuan Xu
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 1721, USA
Neuroimage 40:1003-15. 2008..However, the sample sizes of disease groups are relatively low; further studies with more AD/VaD data are needed...
Pharmacological approaches to managing migraine and associated comorbidities--clinical considerations for monotherapy versus polytherapyStephen D Silberstein
Thomas Jefferson University, Philadelphia, PA 19107, USA
Headache 47:585-99. 2007....
Head or neck injury increases the risk of chronic daily headache: a population-based studyJames R Couch
Department of Neurology, University of Oklahoma Medical School, Oklahoma City, OK 73104, USA
Neurology 69:1169-77. 2007..To evaluate the extent to which head and neck injury (HANI) contributes to chronic daily headache (CDH)...
Migraine and cognitive function: some reassuring newsMitchell S V Elkind
Neurology 64:590-1. 2005
