D E McClain

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. ncbi request reprint Biological effects of embedded depleted uranium (DU): summary of armed forces radiobiology research institute research
    D E McClain
    Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Sci Total Environ 274:115-8. 2001
  2. ncbi request reprint Pyruvate prevents hydrogen peroxide-induced apoptosis
    N Ramakrishnan
    Department of Applied Cellular Radiobiology, Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20889 5603, USA
    Free Radic Res 29:283-95. 1998
  3. ncbi request reprint Detection of depleted uranium in biological samples from Gulf War veterans
    S J Hodge
    Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
    Mil Med 166:69-70. 2001
  4. ncbi request reprint Staining of intracellular deposits of uranium in cultured murine macrophages
    J F Kalinich
    Applied Cellular Radiobiology Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Biotech Histochem 76:247-52. 2001
  5. ncbi request reprint 4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines
    J F Kalinich
    Applied Cellular Radiobiology Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Free Radic Res 33:349-58. 2000

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Biological effects of embedded depleted uranium (DU): summary of armed forces radiobiology research institute research
    D E McClain
    Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Sci Total Environ 274:115-8. 2001
    ..It also altered neurophysiological parameters in rat hippocampus, crossed the placental barrier, and entered fetal tissue. This report summarizes AFRRI's depleted uranium research to date...
  2. ncbi request reprint Pyruvate prevents hydrogen peroxide-induced apoptosis
    N Ramakrishnan
    Department of Applied Cellular Radiobiology, Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20889 5603, USA
    Free Radic Res 29:283-95. 1998
    ..The results suggest that pyruvate has therapeutic potential for use in the treatment of oxidative stress-induced disorders associated with increased apoptosis...
  3. ncbi request reprint Detection of depleted uranium in biological samples from Gulf War veterans
    S J Hodge
    Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
    Mil Med 166:69-70. 2001
    ..By demonstrating the absence of DU in soldiers who suspect exposure by inhalation or ingestion, the assay should reduce psychological stress in these individuals...
  4. ncbi request reprint Staining of intracellular deposits of uranium in cultured murine macrophages
    J F Kalinich
    Applied Cellular Radiobiology Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Biotech Histochem 76:247-52. 2001
    ..Staining intensity correlated with both uranyl nitrate concentration and incubation time. Our method provides a simple procedure for detecting intracellular uranium deposits in macrophages...
  5. ncbi request reprint 4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines
    J F Kalinich
    Applied Cellular Radiobiology Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
    Free Radic Res 33:349-58. 2000
    ..These results suggest that peroxidative damage to cellular membranes resulting in the production of HNE may be a trigger for the induction of apoptosis in immune system cells...