Research Topics
Species | Geoffrey LingSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Cullin 5 gene expression in the rat cerebral cortex and hippocampus following traumatic brain injury (TBI)Xiang Lan Yao
Graduate Program in Neuroscience, F Edmund Hérbert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 4799, USA
Neurosci Lett 409:65-9. 2006..Since Cul-5 is ubiquitously expressed in eukaryotic cells and is linked to proteasome-mediated protein degradation, it may have a role in CNS cell fate determination under conditions of traumatic stress...
Antiplatelet therapy for secondary prevention in stroke � making the right choiceGeoffrey Ling
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Curr Vasc Pharmacol 10:225-37. 2012..The critical assessment of emerging trial data and its impact on existing treatment guidelines may aid in choosing the most appropriate antiplatelet regimen for comprehensive secondary prevention following stroke...
Explosive blast neurotraumaGeoffrey Ling
Department of Neurology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
J Neurotrauma 26:815-25. 2009..Sadly, this military-specific disease has significant potential to become a civilian one as well...
Management of traumatic brain injury in the intensive care unitGeoffrey S F Ling
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 21042, USA
Neurol Clin 26:409-26, viii. 2008....
Aggressive management of ischemic stroke: the case for the hospitalistGeoffrey S F Ling
Department of Neurology, Room A1036, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
J Hosp Med 3:S9-14. 2008
Surgical innovations arising from the Iraq and Afghanistan warsGeoffrey S F Ling
Department of Neurology, Division of Critical Care Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
Annu Rev Med 61:457-68. 2010..In Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF), modern changes in medical management, coupled with improved protective gear and evacuation capabilities, have facilitated the highest survival rate in combat history...
Traumatic brain injury in modern warGeoffrey S F Ling
Department of Neurology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland, USA
Curr Opin Anaesthesiol 24:124-30. 2011..To review the emerging literature on traumatic brain injury (TBI) caused by explosive blast...
U.S. neurologists in Iraq: personal perspectiveGeoffrey Ling
Medical Corps, U.S. Army, Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Neurology 67:14-7. 2006
Preventing ischemic stroke in the older adultGeoffrey S F Ling
Department of Neurology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Cleve Clin J Med 72:S14-25. 2005..Carotid endarterectomy should be considered for stroke prevention in patients with ischemic symptoms; for patients with asymptomatic stenosis, potential benefit must be balanced against surgical risk...
Maintaining cerebral perfusion pressure is a worthy clinical goalGeoffrey S F Ling
Department of Neurology, The Uniformed Services University of the Health Science, Bethesda, MD 20814, USA
Neurocrit Care 2:75-81. 2005..Therefore, for a variety of reasons, the physician may be most prudent to use the published CPP guideline of 70 mmHg until a consensus statement is published advocating a different value...
Time-dependent changes of protein biomarker levels in the cerebrospinal fluid after blast traumatic brain injuryFarid Ahmed
Department of Anatomy, Physiology and Genetics, Uniformed Services University, Bethesda, MD 20814, USA
Electrophoresis 33:3705-11. 2012....
Wartime traumatic cerebral vasospasm: recent review of combat casualtiesRocco A Armonda
Department of Neurosurgery, National Naval Medical Center, Bethesda, Maryland 20814, USA
Neurosurgery 59:1215-25; discussion 1225. 2006..A consequence of this is cerebral vasospasm. This study evaluated all inpatient neurosurgical consults related to battle injury from OIF...
Progesterone differentially regulates pro- and anti-apoptotic gene expression in cerebral cortex following traumatic brain injury in ratsXiang Lan Yao
Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
J Neurotrauma 22:656-68. 2005..These data indicate that one of the neuroprotective mechanisms of progesterone may be related to its differential regulation of apoptotic signals...
Neuro-Critical care in modern warGeoffrey Ling
Uniformed Services University of the Health Sciences, USA
J Trauma 62:S102. 2007
Time-dependent changes in serum biomarker levels after blast traumatic brain injuryAndrea Gyorgy
Department of Anatomy, Physiology and Genetics, Uniformed Services University USU, School of Medicine, Bethesda, Maryland 20814, USA
J Neurotrauma 28:1121-6. 2011..If additional studies verify our findings, the observed early peak of serum NF-H levels can be developed into a useful diagnostic tool for predicting the extent of damage following bTBI...
Oral antiplatelet therapy in the secondary prevention of atherothrombotic eventsGeoffrey Ling
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Am J Cardiovasc Drugs 9:197-209. 2009..This article reviews the benefits and risks of antiplatelet therapy in patients with cardiovascular disease with the aim of spurring greater adherence to treatment recommendations and, thereby, better patient outcomes...
Traumatic brain injury in the rat using the fluid-percussion modelGeoffrey S F Ling
Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Curr Protoc Neurosci . 2004..This unit describes an impact-induced brain trauma model in rats which replicates nonpenetrating head injury. It does not model either penetrating or ischemic brain injuries...
Effect of penetrating brain injury on aquaporin-4 expression using a rat modelChris J Neal
National Naval Medical Center, and Neurotrauma Laboratory, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Neurotrauma 24:1609-17. 2007..Our results demonstrate dynamic spatial and temporal changes in AQP4 expression that contribute to the molecular pathophysiology of PBI...
Bone morphogenetic protein-2 used in spinal fusion with spinal cord injury penetrates intrathecally and elicits a functional signaling cascadeAnton E Dmitriev
Department of Pharmacology, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
Spine J 10:16-25. 2010..However, there are no data establishing the effects of rhBMP-2 on the injured spinal cord...
Physician knowledge of the Glasgow Coma ScaleRonald G Riechers
Department of Neurology, Walter Reed Army Medical Center, Washington, D C 20307, USA
J Neurotrauma 22:1327-34. 2005..It is concluded that, to optimize outcome from combat related head injury, methods for improving accurate quantitation of neurologic state need to be explored...
Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the ratAnthony J Williams
Walter Reed Army Institute of Research, Department of Applied Neurobiology, Silver Spring, MD 20910, USA
Neurosci Lett 408:183-8. 2006....
Role of aspirin in MATCHGeoffrey S F Ling
Lancet 364:1661; author reply 1662-3. 2004
Elevated cerebral blood flow velocities in Fabry disease with reversal after enzyme replacementDavid F Moore
Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda Md 20892-1260, USA
Stroke 33:525-31. 2002..CONCLUSIONS: Patients with Fabry disease have elevated cerebral blood flow velocities. These velocities significantly improved with enzyme replacement therapy...
