David Larson

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. pmc Histamine release and surface CD200R1 staining as sensitive methods for assessing murine mast cell activation
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, USA
    J Immunol Methods 379:15-22. 2012
  2. pmc Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA
    J Immunol 188:4188-99. 2012
  3. pmc Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 188:559-68. 2012
  4. pmc Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice
    Marc P Hübner
    Dept of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Clin Immunol 141:205-17. 2011
  5. doi request reprint Vaccination with intestinal tract antigens does not induce protective immunity in a permissive model of filariasis
    C Paul Morris
    Department of Microbiology and Immunology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20852, USA National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
    Exp Parasitol 135:87-95. 2013
  6. doi request reprint Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 185:7426-34. 2010

Collaborators

  • Edward Mitre
  • Marina N Torrero
  • Hajime Karasuyama
  • Marc P Hübner
  • Yinghui Shi
  • C Paul Morris
  • Kristin E Killoran
  • Ellen Mueller
  • Rachel T Cox
  • Holly Evans
  • Fabian Gondorf
  • Kateryna Soloviova
  • Achim Hoerauf
  • J Thomas Stocker
  • Stephen J Davies
  • Kristin V Tarbell

Detail Information

Publications6

  1. pmc Histamine release and surface CD200R1 staining as sensitive methods for assessing murine mast cell activation
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD, USA
    J Immunol Methods 379:15-22. 2012
    ..Further, both approaches can be done on unpurified peritoneal cell populations. By requiring low numbers of cells, these approaches are ideal for investigating mast cell activation in murine models of disease...
  2. pmc Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner
    David Larson
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA
    J Immunol 188:4188-99. 2012
    ....
  3. pmc Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β
    Marc P Hübner
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 188:559-68. 2012
    ..This study demonstrates that L. sigmodontis-mediated protection against diabetes in NOD mice is not dependent on the induction of a type 2 immune shift but does require TGF-β...
  4. pmc Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice
    Marc P Hübner
    Dept of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
    Clin Immunol 141:205-17. 2011
    ..These results demonstrate that anti-FcεR1 therapy delays diabetes onset in NOD mice and suggest that chronic basophil and mast cell activation may represent a new avenue of therapy for Th1-associated autoimmune diseases...
  5. doi request reprint Vaccination with intestinal tract antigens does not induce protective immunity in a permissive model of filariasis
    C Paul Morris
    Department of Microbiology and Immunology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20852, USA National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
    Exp Parasitol 135:87-95. 2013
    ..sigmodontis have some qualities of 'hidden' antigens, but they still sensitize mice to allergic reactions and fail to protect against future infection when given as a vaccine adsorbed to alum/CPG. ..
  6. doi request reprint Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis
    Marina N Torrero
    Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    J Immunol 185:7426-34. 2010
    ..These results demonstrate that basophils amplify type 2 immune responses, but do not serve a protective role, in chronic infection of mice with the filarial nematode L. sigmodontis...