Research Topics
| Michael R LandauerSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Genistein treatment protects mice from ionizing radiation injuryMichael R Landauer
Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
J Appl Toxicol 23:379-85. 2003..These results demonstrate that a single s.c. administration of the flavonoid genistein at non-toxic doses provides protection against acute radiation injury...
Effects of genistein administration on cytokine induction in whole-body gamma irradiated miceVijay K Singh
Department of Radiation Biology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20889 5603, USA
Int Immunopharmacol 9:1401-10. 2009....- Captopril modulates hypoxia-inducible factors and erythropoietin responses in a murine model of total body irradiationMichal Barshishat-Kupper
Department of Pharmacology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20892, USA
Exp Hematol 39:293-304. 2011..Here we investigate captopril and radiation regulation of erythropoietin (EPO) and thrombopoietin (TPO), key effectors of erythroid progenitor proliferation and differentiation... 
Genistein protects against biomarkers of delayed lung sequelae in mice surviving high-dose total body irradiationRegina M Day
Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
J Radiat Res 49:361-72. 2008..These data suggest that genistein is protective against a range of radiation injuries...- Protection against gamma-irradiation with 5-androstenediolMark H Whitnall
Radiation Casualty Management Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
Mil Med 167:64-5. 2002..Clinical chemistry, histopathology, and behavioral assays showed no evidence of toxicity. We conclude that AED and related steroids are attractive candidates to explore as countermeasures to high- and low-level ionizing radiation... - Nuclear, biological, and chemical combined injuries and countermeasures on the battlefieldGregory B Knudson
Nuclear/Biological/Chemical Interactions and Countermeasures Research Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
Mil Med 167:95-7. 2002..armed forces to accomplish military operations in NBC environments while optimizing both survival and military performance. Preserving combatants' health in an NBC environment will improve warfighting operations and mission capabilities... - Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus)Krinon D Moccia
Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
J Am Assoc Lab Anim Sci 49:323-8. 2010..These results demonstrate that hydration and nutritional gels were not effective methods of supportive care after high-dose total body irradiation in mice... - Antibacterial activity of the soy isoflavone genisteinHyunki Hong
Radiation Infection and Treatment Team, Scientific Research Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Building 42, Bethesda, MD 20889-5603, USA
J Basic Microbiol 46:329-35. 2006..Furthermore, the use of genistein in combination with probiotics may augment the effectiveness of antimicrobial therapies currently used in the management of infections, including those induced by ionizing irradiation... - Radiation-induced performance decrementMichael R Landauer
Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
Mil Med 167:128-30. 2002..Doses higher than 1.25 Gy are likely to degrade performance. Transient performance deficits known as early transient incapacitation observed in animals and humans after large, rapidly delivered doses of ionizing radiation are discussed... - Physiological and psychological impact of low-level radiation: an overviewMichael R Landauer
Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
Mil Med 167:141-2. 2002 - Psychological consequences of military operations in low-level radiation environmentsMichael R Landauer
Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
Mil Med 167:139-40. 2002.... - Subcutaneous administration of genistein prior to lethal irradiation supports multilineage, hematopoietic progenitor cell recovery and survivalThomas A Davis
Naval Medical Research Center, Silver Spring, Maryland, USA
Int J Radiat Biol 83:141-51. 2007..In this study we investigated the mechanism for genistein-induced radioprotection by evaluating the recovery of bone marrow cells and peripheral blood hematology in lethally irradiated mice... - Protection against ionizing radiation by antioxidant nutrients and phytochemicalsJoseph F Weiss
Office of Health Studies, US Department of Energy, EH 6 270 Corporate Square, 1000 Independence Avenue, SW, Washington, DC 20585 0270, USA
Toxicology 189:1-20. 2003..In addition, further studies are required to determine the potential value of specific antioxidant nutrients and phytochemicals during radiotherapy for cancer...