Shilpa Kulkarni

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. ncbi request reprint Hematological targets of radiation damage
    Shilpa Kulkarni
    Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20889, USA
    Curr Drug Targets 11:1375-85. 2010
  2. doi request reprint Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation
    Shilpa Kulkarni
    a Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 173:738-47. 2010
  3. pmc Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, MD 20889 5603, USA
    J Radiat Res 53:526-36. 2012
  4. doi request reprint Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, Maryland 20889 5603, USA
    Radiat Res 171:173-9. 2009
  5. pmc Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, MD 20889 5603, USA
    Mol Biosyst 9:723-31. 2013
  6. doi request reprint Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, USA
    Int J Radiat Biol 85:598-606. 2009
  7. doi request reprint Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol
    Merriline M Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 175:736-45. 2011
  8. doi request reprint Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure
    Shilpa Kulkarni
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of Health Sciences, Bethesda, MD 20889 5603, USA
    Cytokine 62:278-85. 2013

Detail Information

Publications8

  1. ncbi request reprint Hematological targets of radiation damage
    Shilpa Kulkarni
    Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20889, USA
    Curr Drug Targets 11:1375-85. 2010
    ....
  2. doi request reprint Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation
    Shilpa Kulkarni
    a Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 173:738-47. 2010
    ..Our results demonstrate that GT3 protected hematopoietic tissue by preserving the HSCs and HPCs and by preventing persistent DNA damage...
  3. pmc Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, MD 20889 5603, USA
    J Radiat Res 53:526-36. 2012
    ..The results demonstrated that Ex-RAD ameliorates radiation-induced peripheral blood cell depletion, promotes bone marrow recovery, reduces p53 signaling in spleen and protects intestine from radiation injury...
  4. doi request reprint Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, Maryland 20889 5603, USA
    Radiat Res 171:173-9. 2009
    ..In conclusion, it appears that Ex-Rad's radioprotective mechanisms involve prevention of p53-dependent and independent radiation-induced apoptosis...
  5. pmc Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, MD 20889 5603, USA
    Mol Biosyst 9:723-31. 2013
    ..Post-radiation GI injury is a critical determinant of survival after exposure to IR. Our results show a distinct dose and time dependent response to GI tissue injury...
  6. doi request reprint Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector
    Sanchita P Ghosh
    Armed Forces Radiobiology Research Institute, USUHS, Bethesda, USA
    Int J Radiat Biol 85:598-606. 2009
    ..To assess the radioprotective potential of gamma-tocotrienol...
  7. doi request reprint Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol
    Merriline M Satyamitra
    Armed Forces Radiobiology Research Institute AFRRI, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889, USA
    Radiat Res 175:736-45. 2011
    ..05). The large therapeutic potential of and multi-lineage hematopoietic recovery for DT3 warrants further studies...
  8. doi request reprint Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure
    Shilpa Kulkarni
    Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, Uniformed Services University of Health Sciences, Bethesda, MD 20889 5603, USA
    Cytokine 62:278-85. 2013
    ..Our results suggest that induction of high levels of G-CSF by GT3 administration is responsible for its protective efficacy against radiation injury...