Research Topics
| D S KrantzSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Combining psychosocial data to improve prediction of cardiovascular disease risk factors and events: The National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome Evaluation studyKerry S Whittaker
Department of Medical and Clinical Psychology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda 20814, USA
Psychosom Med 74:263-70. 2012..There is overlap among psychosocial predictors of cardiovascular disease (CVD). The usefulness of combining psychosocial variables as risk markers for CVD needs investigation...- Psychotropic medication use and risk of adverse cardiovascular events in women with suspected coronary artery disease: outcomes from the Women's Ischemia Syndrome Evaluation (WISE) studyD S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
Heart 95:1901-6. 2009..This study investigated the relation between psychotropic medication use and adverse cardiovascular (CV) events in women with symptoms of myocardial ischaemia undergoing coronary angiography... 
Anger, hostility, and cardiac symptoms in women with suspected coronary artery disease: the Women's Ischemia Syndrome Evaluation (WISE) StudyDavid S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of Health Sciences, Bethesda, Maryland 20814, USA
J Womens Health (Larchmt) 15:1214-23. 2006..To determine the relationship of anger and hostility to angiographic coronary artery disease (CAD), symptoms, and functional status among women with suspected CAD...- Effects of psychological and social factors on organic disease: a critical assessment of research on coronary heart diseaseDavid S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814 4799, USA
Annu Rev Psychol 53:341-69. 2002..However, continued progress in this area requires multidisciplinary research integrating expertise in cardiology and the behavioral sciences, and more effective efforts to communicate research findings to a biomedical audience... - Effects of mental stress on coronary epicardial vasomotion and flow velocity in coronary artery disease: relationship with hemodynamic stress responsesW J Kop
Department of Medical and Clinical Psychology, Uniformed Services, University of the Health Sciences, Bethesda, Maryland 20814, USA
J Am Coll Cardiol 37:1359-66. 2001..This study examines the prevalence and hemodynamic determinants of mental stress-induced coronary vasoconstriction in patients undergoing diagnostic coronary angiography... - The Psychophysiological Investigations of Myocardial Ischemia (PIMI) study: objective, methods, and variability of measuresP G Kaufmann
National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA
Psychosom Med 60:56-63. 1998..Design and methods of the study are presented... - Circadian variation of ambulatory myocardial ischemia. Triggering by daily activities and evidence for an endogenous circadian componentD S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814 4799, USA
Circulation 93:1364-71. 1996..METHODS and.. 
QT variability during rest and exercise in patients with implantable cardioverter defibrillators and healthy controlsMark C Haigney
Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
Ann Noninvasive Electrocardiol 14:40-9. 2009..The relation between QTVI and arrhythmic vulnerability markers such as T-wave alternans (TWA) has also not been studied. This study examined the effects of exercise on QTVI and TWA in patients with arrhythmic vulnerability...- Major life changes before and after the onset of chronic daily headache: a population-based studyA I Scher
Department of Preventive Medicine and Biometrics, Uniformed Services University, Bethesda, MD, USA
Cephalalgia 28:868-76. 2008..33 (1.2, 1.50) vs. OR 1.04 (0.9, 1.2), P < 0.05 for interaction by age]. These results suggest that major life changes are associated with the onset of chronic daily headache, particularly in middle age... - Effects of acute mental stress and exercise on T-wave alternans in patients with implantable cardioverter defibrillators and controlsWillem J Kop
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
Circulation 109:1864-9. 2004..Exercise-induced T-wave alternans (TWA) is an established marker of cardiac electrical instability. However, the effects of acute mental stress on TWA have not been investigated as a vulnerability marker in humans... - Social network and coronary artery calcification in asymptomatic individualsWillem J Kop
Department of Medical and Clinical Psychology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Psychosom Med 67:343-52. 2005..Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive... - Mental stress hemodynamic responses and myocardial ischemia: does left ventricular dysfunction alter these relationships?Sari D Holmes
Uniformed Services University of the Health Sciences, Department of Medical and Clinical Psychology, Bethesda, MD 20814, USA
Psychosom Med 69:495-500. 2007..To assess if mental stress hemodynamic responses are impaired and related to mental stress (MS) ischemia in patients with left ventricular (LV) dysfunction... - Pyridostigmine, diethyltoluamide, permethrin, and stress: a double-blind, randomized, placebo-controlled trial to assess safetyMichael J Roy
Division of Military Internal Medicine, Department of Medicine, Room A3062, Uniformed Services University, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
Mayo Clin Proc 81:1303-10. 2006..To determine whether short-term human exposure to pyridostigmine bromide, diethyltoluamide, and permethrin, at rest or under stress, adversely affects short-term physical or neurocognitive performance... - Relationship between left ventricular mass and hemodynamic responses to physical and mental stressW J Kop
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
J Psychosom Res 48:79-88. 2000..The present study examines laboratory-induced hemodynamic responses (to exercise, cold, and mental stress) and 24-hour ambulatory measures as predictors of LVM... - Association between symptoms of depression and anxiety with heart rate variability in patients with implantable cardioverter defibrillatorsJennifer L Francis
Department Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Psychosom Med 71:821-7. 2009..Depression and anxiety are associated with autonomic nervous system dysfunction, which may promote the risk of malignant cardiac arrhythmias... - Initial evaluation of N,N-diethyl-m-toluamide and permethrin absorption in human volunteers under stress conditionsMichael J Roy
Department of Medicine, Division of Military Internal Medicine, Room A3062, Uniformed Services University, Bethesda, MD 20814, USA
Mil Med 171:122-7. 2006..CONCLUSIONS: It is possible to blind subjects with respect to DEET and permethrin. Permethrin on clothing does not enter the bloodstream at appreciable levels. Combat videotapes and mental arithmetic can be stressful... - Changes in heart rate and heart rate variability before ambulatory ischemic events(1)W J Kop
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences Bethesda, Bethesda, Maryland 20814, USA
J Am Coll Cardiol 38:742-9. 2001..The aim of this study was to determine the time course of autonomic nervous system activity preceding ambulatory ischemic events... - Mental stress as a trigger of acute cardiac events: the role of laboratory studiesD S Krantz
Department of Medical and Clinical Psychology, Uniformed Services, University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 4799, USA
Ital Heart J 2:895-9. 2001.... - Mental stress and coronary artery disease: a multidisciplinary guideSari D Holmes
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA
Prog Cardiovasc Dis 49:106-22. 2006..As multidisciplinary research in this area continues, one major goal is the better integration of psychosocial knowledge and measures with cardiology research and practice... - Social networks and incident stroke among women with suspected myocardial ischemiaThomas Rutledge
Department of Psychiatry, VA San Diego Healthcare System, University of California, San Diego, CA 92161, USA
Psychosom Med 70:282-7. 2008..Social networks are an independent predictor of all-cause and cardiovascular mortality, but their relationship with stroke events in at-risk populations is largely unknown... - Effects of acute mental stress and exercise on inflammatory markers in patients with coronary artery disease and healthy controlsWillem J Kop
University of Maryland Medical Center, Baltimore, Maryland, USA
Am J Cardiol 101:767-73. 2008..These stress-induced increases are larger than in healthy subjects, occur in the absence of myocardial ischemia, and are related to the neurohormonal stress response... - Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: Results from the Psychophysiological Investigations of Myocardial Ischemia studyDavid S Sheps
University of Florida College of Medicine, the Malcom Randall Veterans Affairs Medical Center, and the Medical Research Service of the Department of Veterans Affairs, Gainesville, Fla 32610 0277, USA
Circulation 105:1780-4. 2002..Ischemia during laboratory mental stress tests has been linked to significantly higher rates of adverse cardiac events. Previous studies have not been designed to detect differences in mortality rates... - Hostility scores are associated with increased risk of cardiovascular events in women undergoing coronary angiography: a report from the NHLBI-Sponsored WISE StudyMarian B Olson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Psychosom Med 67:546-52. 2005..To evaluate hostility-related personality traits assessed by the Cook Medley Hostility Inventory and to relate these to the occurrence of adverse cardiac events in women with suspected myocardial ischemia... - Comparison of mental stress-induced myocardial ischemia in coronary artery disease patients with versus without left ventricular dysfunctionOla Akinboboye
Saint Francis Hospital, Roslyn, State University of New York at Stony Brook, Stony Brook, New York, USA
Am J Cardiol 95:322-6. 2005..These data suggest that mental stress ischemia may be of particular clinical importance in patients who have coronary artery disease and LV dysfunction... - Effects of mental stress on flow-mediated brachial arterial dilation and influence of behavioral factors and hypercholesterolemia in subjects without cardiovascular diseaseJohn S Gottdiener
Division of Cardiology, St Francis Hospital, 100 Port Washington Boulevard, Roslyn, NY 11516, USA
Am J Cardiol 92:687-91. 2003..Mental stress inhibits flow-mediated vasodilation in normal subjects and those with hypercholesterolemia. The magnitude of this inhibition is associated with hostility... - Relationship of socioeconomic markers to daily life ischemia and blood pressure reactivity in coronary artery disease patientsSonia Suchday
Albert Einstein College of Medicine, Department of Clinical Health Psychology, Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY 10461, USA
Ann Behav Med 30:74-84. 2005.... - Depression, the metabolic syndrome and cardiovascular riskViola Vaccarino
Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
Psychosom Med 70:40-8. 2008..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
Research Grants
- Biobehavioral Precipitating Factors in Heart FailureDavid Krantz; Fiscal Year: 2009..This clinical research project will identify and enhanced understanding of the emotional stress and other precipitants of HF decompensation that will aid in preventive and treatment efforts. ..
- Biobehavioral Precipitating Factors in Heart FailureDavid Krantz; Fiscal Year: 2007..This clinical research project will identify and enhanced understanding of the emotional stress and other precipitants of HF decompensation that will aid in preventive and treatment efforts. ..
- Behavioral Medicine and Cardiovascular Research TrainingDavid Krantz; Fiscal Year: 2007....
- BIOBEHAVIORAL TRIGGERS OF VENTRICULAR ARRHYTHMIASDavid Krantz; Fiscal Year: 2001..Using a combination of non-invasive and Invasive methodologies, this project will assess possible mechanisms that may link the asymptomatic development of CAD to the occurrence of health damaging clinical events. ..
- BIOBEHAVIORAL TRIGGERS OF MYOCARDIAL ISCHEMIADavid Krantz; Fiscal Year: 1993..Using a combination of non-invasive and Invasive methodologies, this project will assess possible mechanisms that may link the asymptomatic development of CAD to the occurrence of health damaging clinical events...
- Biobehavioral Precipitating Factors in Heart FailureDavid S Krantz; Fiscal Year: 2010..This clinical research project will identify and enhanced understanding of the emotional stress and other precipitants of HF decompensation that will aid in preventive and treatment efforts. ..