David M Jacobowitz

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. ncbi Microglia activation along the corticospinal tract following traumatic brain injury in the rat: a neuroanatomical study
    David M Jacobowitz
    Department of Anatomy, Uniformed Services University School of Medicine, Bethesda, MD, USA
    Brain Res 1465:80-9. 2012
  2. ncbi Immunohistochemical localization of Phosphoglycerate mutase in capillary endothelium of the brain and periphery
    David M Jacobowitz
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, Bethesda, MD 20814 4799, USA
    Microvasc Res 76:89-93. 2008
  3. ncbi Nuclear-cytoplasmic localization of acetyl coenzyme a synthetase-1 in the rat brain
    Prasanth S Ariyannur
    Department of Anatomy, Molecular and Cell Biology Program and Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Comp Neurol 518:2952-77. 2010
  4. ncbi Extensive aspartoacylase expression in the rat central nervous system
    John R Moffett
    Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Glia 59:1414-34. 2011
  5. ncbi De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, Bethesda, Maryland 20814, USA
    Mol Cell Proteomics 5:1628-37. 2006
  6. ncbi Gender dependence for a subset of the low-abundance signaling proteome in human platelets
    Ofer Eidelman
    Department of Anatomy, Physiology and Genetics, USU Center for Medical Proteomics, Uniformed Services University, School of Medicine, USUHS, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Hum Genomics Proteomics 2010:164906. 2010
  7. ncbi Protein microarray platforms for clinical proteomics
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, USUHS, Bethesda, MD, USA
    Proteomics Clin Appl 1:934-52. 2007
  8. ncbi Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease
    Aryan M A Namboodiri
    Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
    Adv Exp Med Biol 576:145-63; discussion 361-3. 2006
  9. ncbi Craniotomy: true sham for traumatic brain injury, or a sham of a sham?
    Jeffrey T Cole
    Department of Neurology, Uniformed Services University of the Health Sciences, Silver Spring, Maryland, USA
    J Neurotrauma 28:359-69. 2011
  10. ncbi High abundance protein profiling of cystic fibrosis lung epithelial cells
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, USUHS, Bethesda, MD 20814, USA
    Proteomics 5:2210-26. 2005

Collaborators

Detail Information

Publications13

  1. ncbi Microglia activation along the corticospinal tract following traumatic brain injury in the rat: a neuroanatomical study
    David M Jacobowitz
    Department of Anatomy, Uniformed Services University School of Medicine, Bethesda, MD, USA
    Brain Res 1465:80-9. 2012
    ..The role of persistent activation of microglia has not been determined...
  2. ncbi Immunohistochemical localization of Phosphoglycerate mutase in capillary endothelium of the brain and periphery
    David M Jacobowitz
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, Bethesda, MD 20814 4799, USA
    Microvasc Res 76:89-93. 2008
    ..In view of the fact that PGAM1 increases in a variety of tumors, we suggest that PGAM1 may have a pathological role of vascular invasion into cancerous tissue...
  3. ncbi Nuclear-cytoplasmic localization of acetyl coenzyme a synthetase-1 in the rat brain
    Prasanth S Ariyannur
    Department of Anatomy, Molecular and Cell Biology Program and Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Comp Neurol 518:2952-77. 2010
    ..Neuronal and axonal localization implicates AceCS1 in cytoplasmic acetylation reactions in some neurons...
  4. ncbi Extensive aspartoacylase expression in the rat central nervous system
    John R Moffett
    Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Glia 59:1414-34. 2011
    ..Expression of ASPA in microglia may indicate a role in lipid synthesis in these cells, whereas expression in axons suggests that some neurons can both synthesize and catabolize NAA...
  5. ncbi De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, Bethesda, Maryland 20814, USA
    Mol Cell Proteomics 5:1628-37. 2006
    ..We anticipate that this novel hybrid approach to discovery of the high abundance CF proteome will find general application to other proteomic problems in biology and medicine...
  6. ncbi Gender dependence for a subset of the low-abundance signaling proteome in human platelets
    Ofer Eidelman
    Department of Anatomy, Physiology and Genetics, USU Center for Medical Proteomics, Uniformed Services University, School of Medicine, USUHS, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Hum Genomics Proteomics 2010:164906. 2010
    ..The difference may suggest a biological mechanism for gender discrimination in cardiovascular disease...
  7. ncbi Protein microarray platforms for clinical proteomics
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, USUHS, Bethesda, MD, USA
    Proteomics Clin Appl 1:934-52. 2007
    ..We anticipate that these platforms will eventually evolve to accommodate label-free detection technologies, human genome-scale numbers of analytes, and increases in analytic and bioinformatic speeds...
  8. ncbi Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease
    Aryan M A Namboodiri
    Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA
    Adv Exp Med Biol 576:145-63; discussion 361-3. 2006
  9. ncbi Craniotomy: true sham for traumatic brain injury, or a sham of a sham?
    Jeffrey T Cole
    Department of Neurology, Uniformed Services University of the Health Sciences, Silver Spring, Maryland, USA
    J Neurotrauma 28:359-69. 2011
    ..Any experimental design incorporating "sham" procedures should distinguish among sham, experimentally injured, and healthy/naïve animals, to help reduce confounding factors...
  10. ncbi High abundance protein profiling of cystic fibrosis lung epithelial cells
    Harvey B Pollard
    Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, USUHS, Bethesda, MD 20814, USA
    Proteomics 5:2210-26. 2005
    ....
  11. ncbi Immunohistochemical localization of aspartoacylase in the rat central nervous system
    Chikkathur N Madhavarao
    Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Comp Neurol 472:318-29. 2004
    ..The predominant immunoreactivity in oligodendrocytes is consistent with the proposed role of ASPA in myelination, supporting the case for acetate supplementation as an immediate and inexpensive therapy for infants diagnosed with CD...
  12. ncbi Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology
    Hongna Pan
    Department of Neurology and Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Neurotoxicology 33:1219-29. 2012
    ..We also show that subcutaneous injection of α-linolenic acid shows greater neuroprotective efficacy compared with intravenous injection in a brain region-specific manner...
  13. ncbi Pooled ORF expression technology (POET): using proteomics to screen pools of open reading frames for protein expression
    William K Gillette
    Protein Expression Laboratory, Research Technology Program, SAIC-Frederick, Inc./NCI, National Institutes of Health, Frederick, Maryland 21702, USA
    Mol Cell Proteomics 4:1647-52. 2005
    ..Using POET, pools of ORFs can be constructed, and the pools of the resulting proteins can be analyzed and manipulated to rapidly acquire information about the attributes of hundreds of proteins simultaneously...