Research Topics
| Thomas B ElliottSummaryAffiliation: Uniformed Services University of the Health Sciences Country: USA Publications
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Detail Information
Publications
Combined injury: factors with potential to impact radiation dose assessmentsG David Ledney
Scientific Research Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
Health Phys 98:145-52. 2010..Because trauma to irradiated personnel and medical countermeasures may affect biodosimetric measurements, it will be necessary to quickly determine radiation dose in order to implement appropriate therapy...
Antimicrobial therapies for pulmonary Klebsiella pneumoniae infection in B6D2F1/J mice immunocompromised by use of sublethal irradiationDavid E Bentzel
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814, USA
Comp Med 54:185-92. 2004..pneumoniae pneumonia using a third-generation cephalosporin, with or without an aminoglycoside...
Comparison of clarithromycin and ciprofloxacin therapy for Bacillus anthracis Sterne infection in mice with or without (60)Co gamma-photon irradiationItzhak Brook
Scientific Research Department, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
J Med Microbiol 54:1157-62. 2005..B. anthracis Sterne only was isolated from 25-50 % of treated mice with or without irradiation. Mixed infections with B. anthracis Sterne were present in 50-71 % of gamma-irradiated mice but only in 5-10 % of mice without irradiation...
Management of postirradiation infection: lessons learned from animal modelsItzhak Brook
Radiation Medicine Department, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889-5603, USA
Mil Med 169:194-7. 2004..Based on these findings, antimicrobial agents recommended for therapy of infection after exposure to irradiation are: ciprofloxacin, levofloxacin, ceftriaxone, cefepime, gentamicin +/- amoxicillin, or vancomycin...
Antimicrobial therapy for bacillus anthracis-induced polymicrobial infection in (60)Co gamma-irradiated miceThomas B Elliott
Nuclear, Biological, and Chemical Interactions and Countermeasures Research Team, Radiation Medicine Department, Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20889 5603, USA
Antimicrob Agents Chemother 46:3463-71. 2002..To limit mortality following nonlethal irradiation and challenge with B. anthracis spores, antimicrobial therapy needs to be initiated within a few hours after challenge and continued for up to 21 days...
Susceptibility of irradiated B6D2F1/J mice to Klebsiella pneumoniae administered intratracheally: a pulmonary infection model in an immunocompromised hostChristopher E Keller
Center of Laboratory Animal Medicine, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814-4799, USA
Comp Med 53:397-403. 2003..001). These results demonstrate that 7-Gy 60Co gamma-photon radiation in combination with intratracheal K. pneumoniae challenge induces a valid pulmonary infection model in immunocompromised female B6D2F1/J mice...
Wound trauma alters ionizing radiation dose assessmentJuliann G Kiang
Radiation Combined Injury Program, Armed Forces Radiobiology Research Institute, Bethesda, MD 20889 5603, USA
Cell Biosci 2:20. 2012..abstract:..
α-Tocopherol succinate protects mice against radiation-induced gastrointestinal injuryPankaj K Singh
Radiation Countermeasures Program, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Ave, Bethesda, MD 20889 5603, USA
Radiat Res 177:133-45. 2012..Our data suggest that α-TS protects mice from radiation-induced gastrointestinal damage by inhibiting apoptosis, promoting regeneration of crypt cells, and inhibiting translocation of gut bacteria...
Wound trauma increases radiation-induced mortality by activation of iNOS pathway and elevation of cytokine concentrations and bacterial infectionJuliann G Kiang
Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20889 5603, USA
Radiat Res 173:319-32. 2010..Agents that inhibit these responses may prove to be therapeutic for combined injury and may reduce related mortality...
Nuclear, biological, and chemical combined injuries and countermeasures on the battlefieldGregory B Knudson
Nuclear/Biological/Chemical Interactions and Countermeasures Research Team, Armed Forces Radiobiology Research Institute, 8901 Wisconsin Avenue, Bethesda, MD 20889-5603, USA
Mil Med 167:95-7. 2002..armed forces to accomplish military operations in NBC environments while optimizing both survival and military performance. Preserving combatants' health in an NBC environment will improve warfighting operations and mission capabilities...
