Hung Caohuy

Summary

Affiliation: Uniformed Services University of the Health Sciences
Country: USA

Publications

  1. pmc Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway
    Hung Caohuy
    Department of Anatomy, Physiology, and Genetics, Uniformed Services University School of Medicine, Bethesda, Maryland 20814, USA
    J Biol Chem 284:25241-53. 2009
  2. pmc Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor
    QingFeng Yang
    Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Proc Natl Acad Sci U S A 102:9631-6. 2005
  3. ncbi request reprint Amphiphilic pyridinium salts block TNF alpha/NF kappa B signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells
    Susanna Tchilibon
    Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem Pharmacol 70:381-93. 2005
  4. pmc Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells
    Meera Srivastava
    Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Bethesda, MD 20814, USA
    Proc Natl Acad Sci U S A 101:7693-8. 2004
  5. ncbi request reprint Protein kinase C and guanosine triphosphate combine to potentiate calcium-dependent membrane fusion driven by annexin 7
    Hung Caohuy
    Department of Anatomy, Physiology, and Genetics, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Biol Chem 277:25217-25. 2002

Collaborators

  • Meera Srivastava
  • Jian Zhang
  • Yong Lin
  • QingFeng Yang
  • Harvey B Pollard
  • Susanna Tchilibon
  • Catherine Jozwik
  • Bette S Pollard
  • Mirta Glasman
  • Dominic Esposito
  • James Hartley
  • Haksung Kim
  • William Gillette
  • Kenneth A Jacobson
  • Wei Huang
  • Ofer Eidelman

Detail Information

Publications5

  1. pmc Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway
    Hung Caohuy
    Department of Anatomy, Physiology, and Genetics, Uniformed Services University School of Medicine, Bethesda, Maryland 20814, USA
    J Biol Chem 284:25241-53. 2009
    ..These data suggest that the SGK1/Nedd4-2 signaling pathway regulates both CFTR and ENaC trafficking in CF epithelial cells...
  2. pmc Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor
    QingFeng Yang
    Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Proc Natl Acad Sci U S A 102:9631-6. 2005
    ..All other antiinflammatory effects of digitoxin on NF-kappaB and c-Jun N-terminal kinase pathways appear to follow from the blockade of this initial upstream signaling event...
  3. ncbi request reprint Amphiphilic pyridinium salts block TNF alpha/NF kappa B signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells
    Susanna Tchilibon
    Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem Pharmacol 70:381-93. 2005
    ....
  4. pmc Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells
    Meera Srivastava
    Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Bethesda, MD 20814, USA
    Proc Natl Acad Sci U S A 101:7693-8. 2004
    ..We therefore suggest that digitoxin, with its lengthy history of human use, deserves consideration as a candidate drug for suppressing IL-8-dependent lung inflammation in CF...
  5. ncbi request reprint Protein kinase C and guanosine triphosphate combine to potentiate calcium-dependent membrane fusion driven by annexin 7
    Hung Caohuy
    Department of Anatomy, Physiology, and Genetics, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Biol Chem 277:25217-25. 2002
    ..These results thus lead us to hypothesize that annexin 7 may serve as a common site of action for calcium, guanine nucleotide, and protein kinase C in the exocytotic membrane fusion process in chromaffin cells...