Research Topics
| Jonathan CorrenSummaryAffiliation: UCLA School of Medicine Country: USA Publications
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Detail Information
Publications
Protective effect of montelukast on lower and upper respiratory tract responses to short-term cat allergen exposureTamara T Perry
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ann Allergy Asthma Immunol 93:431-8. 2004..02), with an odds ratio of 2.24 (95% CI, 1.16-4.32) in favor of montelukast. CONCLUSIONS: Montelukast has a protective effect against both lower and upper airway responses during exposure to high levels of cat allergen...- The connection between allergic rhinitis and bronchial asthmaJonathan Corren
Allergy Research Foundation, Los Angeles, California 90025, USA
Curr Opin Pulm Med 13:13-8. 2007..The relationship between allergic rhinitis and asthma has intrigued practicing physicians since the turn of the century. Investigations during the past two decades have led to an increased understanding of this relationship... 
The relationship of rhinitis and asthma, sinusitis, food allergy, and eczemaRicardo A Tan
California Allergy and Asthma Medical Group, 11645 Wilshire Boulevard, Suite 1155, Los Angeles, CA 90025, USA
Immunol Allergy Clin North Am 31:481-91. 2011..Allergic rhinitis and asthma are now increasingly being approached diagnostically and therapeutically as the one-airway concept...- Evaluation and treatment of asthma: an overviewJonathan Corren
David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Am J Manag Care 11:S408-15; quiz S427-33. 2005..Asthma is a chronic, inflammatory condition that requires diligent long-term follow-up. This article will address the diagnostic evaluation of patients with asthma and present an overview of drugs commonly used in treatment... - Lebrikizumab treatment in adults with asthmaJonathan Corren
Allergy Medical Clinic, Los Angeles, California, USA
N Engl J Med 365:1088-98. 2011..We hypothesized that anti-interleukin-13 therapy would benefit patients with asthma who had a pretreatment profile consistent with interleukin-13 activity... - Use of mometasone furoate administered via a dry powder inhaler in the treatment of asthmaMichelle Zeidler
David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Curr Med Res Opin 26:1295-305. 2010..Mometasone furoate delivered via a dry powder inhaler (MF-DPI) is indicated for once-daily maintenance treatment of asthma in patients as young as 4 years old... - Anti-interleukin-5 antibody therapy in asthma and allergiesJonathan Corren
Allergy Medical Clinic, Los Angeles, California, USA
Curr Opin Allergy Clin Immunol 11:565-70. 2011.... - Twelve-week, randomized, placebo-controlled, multicenter study of the efficacy and tolerability of budesonide and formoterol in one metered-dose inhaler compared with budesonide alone and formoterol alone in adolescents and adults with asthmaJonathan Corren
Allergy Research Foundation, Los Angeles, CA 90025, USA
Clin Ther 29:823-43. 2007.... - Small airways disease in asthmaJonathan Corren
Allergy Research Foundation, University of California, Los Angeles, 11620 Wilshire Boulevard 200, Los Angeles, CA 90025, USA
Curr Allergy Asthma Rep 8:533-9. 2008..The recognition of small airways involvement in asthma has clinical relevance, as new formulations of inhaled corticosteroids with smaller particle aerosols may be more effective in addressing this component of asthma... - A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthmaJonathan Corren
Allergy Research Foundation, Los Angeles, CA 90025, USA
Am J Respir Crit Care Med 181:788-96. 2010..AMG 317 is a fully human monoclonal antibody to IL-4Ralpha that blocks both IL-4 and IL-13 pathways... - Review of azelastine nasal spray in the treatment of allergic and non-allergic rhinitisChristina Lee
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Section of Clinical Immunology and Allergy, University of California, Los Angeles, Los Angeles, CA, USA
Expert Opin Pharmacother 8:701-9. 2007..Given its unique pharmacologic properties and clinical profile, azelastine maintains an important role in the treatment of chronic rhinitis... - Omalizumab in the treatment of asthmaRicardo Tan
California Allergy and Asthma Medical Group Inc, 11645 Wilshire Boulevard, Suite 1155, Los Angeles, CA 90025, USA
Expert Rev Respir Med 5:747-56. 2011..In our opinion, omalizumab is well-tolerated and significantly improves pulmonary function, decreases clinical symptoms and improves the quality of life in patients with uncontrolled allergic asthma... - Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitisJonathan Corren
Allergy Research Foundation, Inc, Los Angeles, California 90025, USA
Clin Ther 27:543-53. 2005..Azelastine nasal spray and oral cetirizine are selective histamine H(1)-receptor antagonists that are approved in the United States for the treatment of seasonal allergic rhinitis (SAR)... - Effects of omalizumab on changes in pulmonary function induced by controlled cat room challengeJonathan Corren
Allergy Medical Clinic, Research Division, Los Angeles, CA, USA
J Allergy Clin Immunol 127:398-405. 2011..Environmental exposure to cat allergen is common, and sensitization to cat allergens is strongly associated with asthma... - Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapyJonathan Corren
Allergy Research Foundation, Los Angeles, CA 90025, USA
J Allergy Clin Immunol 121:506-11. 2008..It is not known whether stopping or reducing the dose of omalizumab maintains adequate suppression of free IgE levels and IgE-mediated mast cell activation... 
Clinical and biochemical effects of a combination botanical product (ClearGuard) for allergy: a pilot randomized double-blind placebo-controlled trialJonathan Corren
Allergy Research Foundation, Los Angeles, USA
Nutr J 7:20. 2008..The current study was conducted to determine the effects of these combined ingredients upon the nasal response to allergen challenge in patients with seasonal allergic rhinitis...- Safety of omalizumab in asthmaRicardo A Tan
California Allergy and Asthma Medical Group, 11645 Wilshire Blvd, Suite 1155, Los Angeles, CA 90025, USA
Expert Opin Drug Saf 10:463-71. 2011..As part of a relatively new class of agents, continued surveillance is needed as its indications expand and its use in the population continues to grow... - Cytokine inhibition in severe asthma: current knowledge and future directionsJonathan Corren
Research Division, Allergy Medical Clinic, Los Angeles, California 90025, USA
Curr Opin Pulm Med 17:29-33. 2011..Existing data from clinical trials of cytokine antagonists in asthmatic patients are then reviewed to determine the efficacy and safety of these compounds... - Budesonide/formoterol in the treatment of asthmaChristina Lee
Department of Medicine, Division of Allergy and Immunology, VA Greater Los Angeles Healthcare System University of California Los Angeles, Los Angeles, CA, USA
Expert Rev Respir Med 2:551-64. 2008..Use of this approach has resulted in studies evaluating SMART, demonstrating significantly lower rates of exacerbations and reliever medication use compared with fixed-dosing regimens in asthma... - Rhinitis therapy and the prevention of hospital care for asthma: a case-control studyJonathan Corren
Allergy Research Foundation, Los Angeles, CA 90025, USA
J Allergy Clin Immunol 113:415-9. 2004..19 to 0.73 and 0.22, 0.07 to 0.63). CONCLUSIONS: In patients with asthma, treatment of concomitant allergic rhinitis was associated with significant reductions in risk of emergency room treatment and hospitalization for asthma... - Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthmaMichelle Zeidler
Department of Pulmonary and Critical Care Medicine, University of California, Los Angeles, California 90025, USA
Treat Respir Med 3:35-44. 2004..Future studies, involving histopathologic and clinical endpoints, will be necessary to determine whether treatment with HFA solutions offers significant advantages over currently available therapies... - Relationship between nonallergic upper airway disease and asthmaJonathan Corren
Department of Medicine, University of California, Los Angeles, California, USA
Clin Allergy Immunol 19:101-14. 2007..Finally, given this complex relationship between localized and systemic inflammation, it behooves all physicians to assess and treat rhinitis and sinusitis when they are present in patients with asthma... - Immunomodulation of asthma: where do we stand?Jonathan Corren
Allergy Research Foundation, 11620 Wilshire Boulevard, Suite 200 210, Los Angeles, CA 90025, USA
Curr Allergy Asthma Rep 2:433-5. 2002 - Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthmaJonathan Corren
Allergy Research Foundation, Inc, Los Angeles, Calif 90025, USA
J Allergy Clin Immunol 111:87-90. 2003..25]; P <.01). CONCLUSION: Omalizumab reduces the rate of serious asthma exacerbations and the need for unscheduled outpatient visits, emergency room treatment, and hospitalization in patients with moderate-to-severe allergic asthma... - Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthmaJonathan Corren
Allergy Research Foundation, Inc, Los Angeles, California 90023, USA
Clin Ther 25:776-98. 2003..HFA replaces the chlorofluorocarbon (CFC) propellant of the previous formulation, producing aerosols of smaller average particle size... - Small airways response to naturalistic cat allergen exposure in subjects with asthmaMichelle R Zeidler
Division of Pulmonary, David Geffen School of Medicine and Allergy Research Foundation, University of California, Los Angeles, CA 90025, USA
J Allergy Clin Immunol 118:1075-81. 2006..It is currently unclear whether the small airways (diameter <2 microm) contribute significantly to late asthmatic reactions to inhaled allergen... - Efficacy of once-daily desloratadine/pseudoephedrine for relief of nasal congestionEric Schenkel
Valley Clinical Research Center, 3729 Easton-Nazareth Highway, Suite 202, Easton, PA 18045, USA
Allergy Asthma Proc 23:325-30. 2002..It was concluded that desloratadine/pseudoephedrine offers additional benefit to patients with moderate-to-severe SAR-associated nasal congestion compared with pseudoephedrine therapy alone... - The rhinitis-asthma link revisitedJonathan Corren
Ann Allergy Asthma Immunol 94:311-2. 2005 - Nasal response to natural cat allergen exposure is significantly greater in patients with rhinitis and asthma than in patients with rhinitis aloneJonathan Corren
J Allergy Clin Immunol 115:202-3. 2005 - A cumulative dose study of levalbuterol and racemic albuterol administered by hydrofluoroalkane-134a metered-dose inhaler in asthmatic subjectsKenneth Tripp
Sepracor, Inc, Marlborough, MA 01752, USA
J Allergy Clin Immunol 122:544-9. 2008..The short-acting beta(2)-agonists levalbuterol and racemic albuterol are available for administration through a hydrofluoroalkane-134a (HFA) metered-dose inhaler (MDI)... - Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadineCraig F LaForce
Carolina Allergy and Asthma Consultants, Raleigh, North Carolina 27607, USA
Ann Allergy Asthma Immunol 93:154-9. 2004..Currently available oral second-generation antihistamines do not provide adequate symptom relief for many allergy patients...