Lin Pei

Summary

Affiliation: Tularik Inc
Country: USA

Publications

  1. ncbi Transcriptional repressor of vasoactive intestinal peptide receptor mediates repression through interactions with TFIIB and TFIIEbeta
    L Pei
    Division of Endocrinology and Metabolism, Cedars Sinai Research Institute UCLA School of Medicine, 8700 Beverly Boulevard, Los Angeles, CA 90048, U S A
    Biochem J 360:633-8. 2001
  2. ncbi Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function
    Lin Pei
    Tularik Inc, 1120 Veterans Boulevard, South San Francisco, CA 94080, USA
    Proc Natl Acad Sci U S A 100:7803-7. 2003
  3. ncbi Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene
    David Mu
    Tularik Inc, Genomics Division, 266 E Pulaski Road, Greenlawn, NY 11740, USA
    Cancer Cell 3:297-302. 2003
  4. ncbi PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer
    Lin Pei
    Tularik Inc, South San Francisco, California 94080, USA
    Cancer Res 62:5420-4. 2002
  5. ncbi G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase
    Natalie Lavine
    Centre for Addiction and Mental Health, Department of Pharmacology, Institute of Medical Science, University of Toronto, Ontario M5T 1R8, Canada
    J Biol Chem 277:46010-9. 2002
  6. ncbi Control of synaptic strength, a novel function of Akt
    Qinghua Wang
    Programme in Brain and Behaviour Research, Research Institute of the Hospital for Sick Children, University of Toronto, 555 University Avenue, M5G 1X8, Toronto, Ontario, Canada
    Neuron 38:915-28. 2003
  7. ncbi Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors
    Lin Pei
    Department of Neuroscience, Centre for Addiction and Mental Health, Clarke Division, Toronto, Ontario, M5T 1R8 Canada
    J Neurosci 24:1149-58. 2004

Collaborators

Detail Information

Publications7

  1. ncbi Transcriptional repressor of vasoactive intestinal peptide receptor mediates repression through interactions with TFIIB and TFIIEbeta
    L Pei
    Division of Endocrinology and Metabolism, Cedars Sinai Research Institute UCLA School of Medicine, 8700 Beverly Boulevard, Los Angeles, CA 90048, U S A
    Biochem J 360:633-8. 2001
    ..My results indicate that VIPR-RP mediates transcriptional repression through direct interactions with the general transcription machinery...
  2. ncbi Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function
    Lin Pei
    Tularik Inc, 1120 Veterans Boulevard, South San Francisco, CA 94080, USA
    Proc Natl Acad Sci U S A 100:7803-7. 2003
    ..These results establish a direct link between the potassium channel activity of TASK3 and its oncogenic functions and imply that blockers for this potassium channel may have therapeutic potential for the treatment of cancers...
  3. ncbi Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene
    David Mu
    Tularik Inc, Genomics Division, 266 E Pulaski Road, Greenlawn, NY 11740, USA
    Cancer Cell 3:297-302. 2003
    ....
  4. ncbi PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer
    Lin Pei
    Tularik Inc, South San Francisco, California 94080, USA
    Cancer Res 62:5420-4. 2002
    ..The potent oncogenic activity of PRC17 is likely to influence the tumorigenic phenotype of these prostate cancers...
  5. ncbi G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase
    Natalie Lavine
    Centre for Addiction and Mental Health, Department of Pharmacology, Institute of Medical Science, University of Toronto, Ontario M5T 1R8, Canada
    J Biol Chem 277:46010-9. 2002
    ..The observation that several G protein-coupled receptors form stable complexes with their effectors suggests that this arrangement might be a general feature of G protein-coupled signal transduction...
  6. ncbi Control of synaptic strength, a novel function of Akt
    Qinghua Wang
    Programme in Brain and Behaviour Research, Research Institute of the Hospital for Sick Children, University of Toronto, 555 University Avenue, M5G 1X8, Toronto, Ontario, Canada
    Neuron 38:915-28. 2003
    ..This work also provides evidence for the rapid regulation of neurotransmitter receptor numbers in the postsynaptic domain by direct receptor phosphorylation as an important means of producing synaptic plasticity...
  7. ncbi Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors
    Lin Pei
    Department of Neuroscience, Centre for Addiction and Mental Health, Clarke Division, Toronto, Ontario, M5T 1R8 Canada
    J Neurosci 24:1149-58. 2004
    ....